{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T15:22:40Z","timestamp":1769700160579,"version":"3.49.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,25]]},"DOI":"10.7759\/cureus.102277","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T04:08:31Z","timestamp":1769400511000},"source":"Crossref","is-referenced-by-count":0,"title":["A Case of Antibody-Mediated Recurrent Hypoglycemia in a Patient With Mixed Connective Tissue Disease"],"prefix":"10.7759","author":[{"given":"Niyati","family":"Patel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza","family":"Choudhry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehra","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaitlyn N","family":"Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payal","family":"Shooliz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2018.07.32","article-title":"Insulin autoimmune syndrome: from diagnosis to clinical management","volume":"6","author":"Censi S","year":"2018","unstructured":"Censi S, Mian C, Betterle C. Insulin autoimmune syndrome: from diagnosis to clinical management. Ann Transl Med. 2018, 6:335. 10.21037\/atm.2018.07.32","journal-title":"Ann Transl Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S219438","article-title":"Insulin autoimmune syndrome (Hirata disease): a comprehensive review fifty years after its first description","volume":"13","author":"Cappellani D","year":"2020","unstructured":"Cappellani D, Macchia E, Falorni A, Marchetti P. Insulin autoimmune syndrome (Hirata disease): a comprehensive review fifty years after its first description. Diabetes Metab Syndr Obes. 2020, 13:963-978. 10.2147\/DMSO.S219438","journal-title":"Diabetes Metab Syndr Obes"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/agm2.70007","article-title":"Insulin autoimmune syndrome: a Chinese expert consensus statement","volume":"8","author":"Zhang H","year":"2025","unstructured":"Zhang H, Yuan MX, Pan Q. Insulin autoimmune syndrome: a Chinese expert consensus statement. Aging Med (Milton). 2025, 8:e70007. 10.1002\/agm2.70007","journal-title":"Aging Med (Milton)"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2020.03.011","article-title":"Hypoglycemia induced by hydroxychloroquine sulfate in a patient treated for connective tissue disease without diabetes mellitus","volume":"42","author":"Dai Y","year":"2020","unstructured":"Dai Y, Lin G, Shi D. Hypoglycemia induced by hydroxychloroquine sulfate in a patient treated for connective tissue disease without diabetes mellitus. Clin Ther. 2020, 42:940-945. 10.1016\/j.clinthera.2020.03.011","journal-title":"Clin Ther"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(01)01221-3","article-title":"The inhibition of gluconeogenesis by chloroquine contributes to its hypoglycaemic action","volume":"428","author":"Jarzyna R","year":"2001","unstructured":"Jarzyna R, Kiersztan A, Lisowa O, et al.. The inhibition of gluconeogenesis by chloroquine contributes to its hypoglycaemic action. European J Pharmacol. 2001, 428:381-388. 10.1016\/S0014-2999(01)01221-3","journal-title":"European J Pharmacol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/cen.14987","article-title":"Low-dose diazoxide is safe and effective in infants with transient hyperinsulinism","volume":"100","author":"Malhotra N","year":"2024","unstructured":"Malhotra N, Yau D, Cunjamalay A, et al.. Low-dose diazoxide is safe and effective in infants with transient hyperinsulinism. Clin Endocrinol (Oxf). 2024, 100:132-137. 10.1111\/cen.14987","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2337\/dci18-0033","article-title":"Management of hyperglycemia in type 2 diabetes, 2018: a consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)","volume":"41","author":"Davies MJ","year":"2018","unstructured":"Davies MJ, D'Alessio DA, Fradkin J, et al.. Management of hyperglycemia in type 2 diabetes, 2018: a consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2018, 41:2669-2701. 10.2337\/dci18-0033","journal-title":"Diabetes Care"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/1225676","article-title":"Insulin autoimmune syndrome: a systematic review","volume":"2023","author":"Lin M","year":"2023","unstructured":"Lin M, Chen Y, Ning J. Insulin autoimmune syndrome: a systematic review. Int J Endocrinol. 2023, 2023:1225676. 10.1155\/2023\/1225676","journal-title":"Int J Endocrinol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jecr.2016.05.003","article-title":"Hypoglycemia due to insulin autoimmune syndrome: a rare cause not to be forgotten","volume":"2","author":"Alam S","year":"2016","unstructured":"Alam S, Ozair M, Ahmad J. Hypoglycemia due to insulin autoimmune syndrome: a rare cause not to be forgotten. J Clin Transl Endocrinol Case Rep. 2016, 2:7-9. 10.1016\/j.jecr.2016.05.003","journal-title":"J Clin Transl Endocrinol Case Rep"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.64130","article-title":"Insulin autoimmune syndrome: a case report highlighting diagnostic pitfalls","volume":"16","author":"Okumura H","year":"2024","unstructured":"Okumura H, Inaba S, Kawashima A, Shimizu T. Insulin autoimmune syndrome: a case report highlighting diagnostic pitfalls. Cureus. 2024, 16:e64130. 10.7759\/cureus.64130","journal-title":"Cureus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2337\/diab.45.10.1427","article-title":"Diazoxide treatment at onset preserves residual insulin secretion in adults with autoimmune diabetes","volume":"45","author":"Bj\u00f6rk E","year":"1996","unstructured":"Bj\u00f6rk E, Berne C, K\u00e4mpe O, Wibell L, Oskarsson P, Karlsson FA. Diazoxide treatment at onset preserves residual insulin secretion in adults with autoimmune diabetes. Diabetes. 1996, 45:1427-1430. 10.2337\/diab.45.10.1427","journal-title":"Diabetes"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4158\/ACCR-2018-0258","article-title":"Glucose changes in a patient with insulin autoimmune syndrome demonstrated by continuous glucose monitoring","volume":"5","author":"Lin SD","year":"2019","unstructured":"Lin SD, Hsu SR. Glucose changes in a patient with insulin autoimmune syndrome demonstrated by continuous glucose monitoring. AACE Clin Case Rep. 2019, 5:e35-e39. 10.4158\/ACCR-2018-0258","journal-title":"AACE Clin Case Rep"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/390164-a-case-of-antibody-mediated-recurrent-hypoglycemia-in-a-patient-with-mixed-connective-tissue-disease","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T04:08:33Z","timestamp":1769400513000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/390164-a-case-of-antibody-mediated-recurrent-hypoglycemia-in-a-patient-with-mixed-connective-tissue-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,25]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.102277","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,25]]}}}