{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T09:35:20Z","timestamp":1770370520979,"version":"3.49.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,5]]},"DOI":"10.7759\/cureus.103039","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T18:21:32Z","timestamp":1770315692000},"source":"Crossref","is-referenced-by-count":0,"title":["Perioperative Management of Immune Thrombocytopenic Purpura in Cardiac Surgery: A Systematic Review of the Literature in Urgent and Elective Settings"],"prefix":"10.7759","author":[{"given":"K","family":"Said","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hicham","family":"Kbiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakim","family":"El Baraka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noureddine","family":"El Fassiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayoub","family":"Bouchama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chakib","family":"Chouikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoufal","family":"Elghoul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassam","family":"Bencharfa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihane","family":"Bouzari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Fajri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hicham","family":"Sallahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Margad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adbelatif","family":"Benbouha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Redouane","family":"Roukhsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatim A","family":"El Ghadbane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aznag","family":"Mohamed Amine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Nabil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issam","family":"Serghini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza","family":"Najout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monsif","family":"Salek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdellatif","family":"Chlouchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amine","family":"Bentaher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramiz","family":"Ballouk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mourad","family":"Ababou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatim","family":"Belfquih","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najib","family":"Bouhabba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monsef","family":"Elabdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelmajid","family":"Bouzerda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Khatouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youssef","family":"Qamouss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Zyani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000966","article-title":"American Society of Hematology 2019 guidelines for immune thrombocytopenia","volume":"3","author":"Neunert C","year":"2019","unstructured":"Neunert C, Terrell DR, Arnold DM, et al.. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019, 3:3829-66. 10.1182\/bloodadvances.2019000966","journal-title":"Blood Adv"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000812","article-title":"Updated international consensus report on the investigation and management of primary immune thrombocytopenia","volume":"3","author":"Provan D","year":"2019","unstructured":"Provan D, Arnold DM, Bussel JB, et al.. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv. 2019, 3:3780-817. 10.1182\/bloodadvances.2019000812","journal-title":"Blood Adv"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6020016","article-title":"Pathogenesis\u00a0and\u00a0therapeutic\u00a0mechanisms\u00a0in immune\u00a0thrombocytopenia\u00a0(ITP)","volume":"6","author":"Zufferey A","year":"2017","unstructured":"Zufferey A, Kapur R, Semple JW. Pathogenesis\u00a0and\u00a0therapeutic\u00a0mechanisms\u00a0in immune\u00a0thrombocytopenia\u00a0(ITP). J Clin Med. 2017, 6:10.3390\/jcm6020016","journal-title":"J Clin Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.10.039","article-title":"Thrombocytopenia after cardiopulmonary bypass is associated with increased morbidity and mortality","volume":"110","author":"Griffin BR","year":"2020","unstructured":"Griffin BR, Bronsert M, Reece TB, et al.. Thrombocytopenia after cardiopulmonary bypass is associated with increased morbidity and mortality. Ann Thorac Surg. 2020, 110:50-7. 10.1016\/j.athoracsur.2019.10.039","journal-title":"Ann Thorac Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2021.03.033","article-title":"STS\/SCA\/AmSECT\/SABM update to the clinical practice guidelines on patient blood management","volume":"112","author":"Tibi P","year":"2021","unstructured":"Tibi P, McClure RS, Huang J, et al.. STS\/SCA\/AmSECT\/SABM update to the clinical practice guidelines on patient blood management. Ann Thorac Surg. 2021, 112:981-1004. 10.1016\/j.athoracsur.2021.03.033","journal-title":"Ann Thorac Surg"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2017.06.026","article-title":"2017 EACTS\/EACTA Guidelines on patient blood management for adult cardiac surgery","volume":"32","author":"Boer C","year":"2018","unstructured":"Boer C, Meesters MI, Milojevic M, et al.. 2017 EACTS\/EACTA Guidelines on patient blood management for adult cardiac surgery. J Cardiothorac Vasc Anesth. 2018, 32:88-120. 10.1053\/j.jvca.2017.06.026","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezae352","article-title":"2024 EACTS\/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP","volume":"67","author":"Casselman FP","year":"2025","unstructured":"Casselman FP, Lance MD, Ahmed A, et al.. 2024 EACTS\/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP. Eur J Cardiothorac Surg. 2025, 67:10.1093\/ejcts\/ezae352","journal-title":"Eur J Cardiothorac Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0003-4975(97)00763-7","article-title":"Coronary artery bypass grafting in immune thrombocytopenic purpura","volume":"64","author":"Mathew TC","year":"1997","unstructured":"Mathew TC, Vasudevan R, Leb L, Pezzella SM, Pezzella AT. Coronary artery bypass grafting in immune thrombocytopenic purpura. Ann Thorac Surg. 1997, 64:1059-62. 10.1016\/s0003-4975(97)00763-7","journal-title":"Ann Thorac Surg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9784.109774","article-title":"Cardiac surgery in a patient with immunological thrombocytopenic purpura: complications and precautions","volume":"16","author":"Chowdhry V","year":"2013","unstructured":"Chowdhry V, Mohanty BB, Probodh D. Cardiac surgery in a patient with immunological thrombocytopenic purpura: complications and precautions. Ann Card Anaesth. 2013, 16:147-50. 10.4103\/0971-9784.109774","journal-title":"Ann Card Anaesth"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.18310","article-title":"Aggressive perioperative management for immune thrombocytopenic purpura in a patient undergoing open heart surgery: a correct strategy in an emergent patient?","volume":"13","author":"Mallick H","year":"2021","unstructured":"Mallick H, Siddiqui ST, Khan Y, Ahmad I, Shahabuddin S. Aggressive perioperative management for immune thrombocytopenic purpura in a patient undergoing open heart surgery: a correct strategy in an emergent patient?. Cureus. 2021, 13:e18310. 10.7759\/cureus.18310","journal-title":"Cureus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.xjon.2022.08.016","article-title":"Successful type A aortic dissection repair in the setting of severe immune thrombocytopenia","volume":"13","author":"Yasin A","year":"2023","unstructured":"Yasin A, Medina MG, Dunn TJ, Watkins AC. Successful type A aortic dissection repair in the setting of severe immune thrombocytopenia. JTCVS Open. 2023, 13:49-50. 10.1016\/j.xjon.2022.08.016","journal-title":"JTCVS Open"},{"key":"ref12","article-title":"Coronary artery bypass grafting in idiopathic thrombocytopenia: use of thromboelastometry without platelet transfusion","volume":"37","author":"Rossi M","year":"2010","unstructured":"Rossi M, Lewis M, Hutchinson N. Coronary artery bypass grafting in idiopathic thrombocytopenia: use of thromboelastometry without platelet transfusion. Tex Heart Inst J. 2010, 37:361-4.","journal-title":"Tex Heart Inst J"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(20)30227-1","article-title":"Perioperative oral eltrombopag versus intravenous immunoglobulin in patients with immune thrombocytopenia: a non-inferiority, multicentre, randomised trial","volume":"7","author":"Arnold DM","year":"2020","unstructured":"Arnold DM, Heddle NM, Cook RJ, et al.. Perioperative oral eltrombopag versus intravenous immunoglobulin in patients with immune thrombocytopenia: a non-inferiority, multicentre, randomised trial. Lancet Haematol. 2020, 7:e640-8. 10.1016\/S2352-3026(20)30227-1","journal-title":"Lancet Haematol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.09.061","article-title":"The Society of Thoracic Surgeons, The Society of Cardiovascular Anesthesiologists, and The American Society of ExtraCorporeal Technology: clinical practice guidelines-anticoagulation during cardiopulmonary bypass","volume":"105","author":"Shore-Lesserson L","year":"2018","unstructured":"Shore-Lesserson L, Baker RA, Ferraris VA, Greilich PE, Fitzgerald D, Roman P, Hammon JW. The Society of Thoracic Surgeons, The Society of Cardiovascular Anesthesiologists, and The American Society of ExtraCorporeal Technology: clinical practice guidelines-anticoagulation during cardiopulmonary bypass. Ann Thorac Surg. 2018, 105:650-62. 10.1016\/j.athoracsur.2017.09.061","journal-title":"Ann Thorac Surg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjae.2022.12.003","article-title":"Anticoagulation for cardiopulmonary bypass: part one","volume":"23","author":"Cartwright B","year":"2023","unstructured":"Cartwright B, Mundell N. Anticoagulation for cardiopulmonary bypass: part one. BJA Educ. 2023, 23:110-6. 10.1016\/j.bjae.2022.12.003","journal-title":"BJA Educ"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/02676591231221708","article-title":"Bivalirudin anticoagulation for cardiopulmonary bypass during cardiac surgery","volume":"40","author":"Meshulami N","year":"2025","unstructured":"Meshulami N, Murthy R, Meyer M, Meyer AD, Kaushik S. Bivalirudin anticoagulation for cardiopulmonary bypass during cardiac surgery. Perfusion. 2025, 40:7-19. 10.1177\/02676591231221708","journal-title":"Perfusion"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606424","article-title":"Tranexamic acid in patients undergoing coronary-artery surgery","volume":"376","author":"Myles PS","year":"2017","unstructured":"Myles PS, Smith JA, Forbes A, et al.. Tranexamic acid in patients undergoing coronary-artery surgery. N Engl J Med. 2017, 376:136-48. 10.1056\/NEJMoa1606424","journal-title":"N Engl J Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/461836-perioperative-management-of-immune-thrombocytopenic-purpura-in-cardiac-surgery-a-systematic-review-of-the-literature-in-urgent-and-elective-settings","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T18:21:32Z","timestamp":1770315692000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/461836-perioperative-management-of-immune-thrombocytopenic-purpura-in-cardiac-surgery-a-systematic-review-of-the-literature-in-urgent-and-elective-settings"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,5]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.103039","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,5]]}}}