{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:20:37Z","timestamp":1790234437882,"version":"4.1.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,8]]},"DOI":"10.7759\/cureus.103232","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T04:09:51Z","timestamp":1770610191000},"source":"Crossref","is-referenced-by-count":2,"title":["Predictive Value of the Triglyceride-Glucose Index (TyG Index) for Major Cardiac Events in Patients With Chronic Heart Failure and Type 2 Diabetes: A Prospective Observational Study"],"prefix":"10.7759","author":[{"given":"Md. Fakhrul","family":"Hasan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manzoor","family":"Mahmood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohmmad D","family":"Selim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu","family":"Salim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipal Krishna","family":"Adhikary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khurshid","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02783-9","article-title":"The predictive significance of the triglyceride-glucose index in forecasting adverse cardiovascular events among type 2 diabetes mellitus patients with co-existing hyperuricemia: a retrospective cohort study","volume":"24","author":"Zhao J","year":"2025","unstructured":"Zhao J, Li N, Li S, Dou J. The predictive significance of the triglyceride-glucose index in forecasting adverse cardiovascular events among type 2 diabetes mellitus patients with co-existing hyperuricemia: a retrospective cohort study. Cardiovasc Diabetol. 2025, 24:218. 10.1186\/s12933-025-02783-9","journal-title":"Cardiovasc Diabetol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02687-8","article-title":"Association of triglyceride-glucose index trajectories with the risk of worsening heart failure in elderly patients with chronic heart failure and type 2 diabetes: a competing risk analysis","volume":"24","author":"Lai Y","year":"2025","unstructured":"Lai Y, Lin C, Liu X, et al.. Association of triglyceride-glucose index trajectories with the risk of worsening heart failure in elderly patients with chronic heart failure and type 2 diabetes: a competing risk analysis. Cardiovasc Diabetol. 2025, 24:131. 10.1186\/s12933-025-02687-8","journal-title":"Cardiovasc Diabetol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-023-01895-4","article-title":"Association between the triglyceride-glucose index and the risk of mortality among patients with chronic heart failure: results from a retrospective cohort study in China","volume":"22","author":"Zhou Y","year":"2023","unstructured":"Zhou Y, Wang C, Che H, et al.. Association between the triglyceride-glucose index and the risk of mortality among patients with chronic heart failure: results from a retrospective cohort study in China. Cardiovasc Diabetol. 2023, 22:171. 10.1186\/s12933-023-01895-4","journal-title":"Cardiovasc Diabetol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02671-2","article-title":"Triglyceride glucose index predicts long-term mortality and major adverse cardiovascular events in patients with type 2 diabetes","volume":"24","author":"Sbriscia M","year":"2025","unstructured":"Sbriscia M, Colombaretti D, Giuliani A, et al.. Triglyceride glucose index predicts long-term mortality and major adverse cardiovascular events in patients with type 2 diabetes. Cardiovasc Diabetol. 2025, 24:115. 10.1186\/s12933-025-02671-2","journal-title":"Cardiovasc Diabetol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-40299-y","article-title":"Trends in baseline triglyceride-glucose index and association with predicted 10-year cardiovascular disease risk among type 2 diabetes patients in Thailand","volume":"13","author":"Lertsakulbunlue S","year":"2023","unstructured":"Lertsakulbunlue S, Mungthin M, Rangsin R, Kantiwong A, Sakboonyarat B. Trends in baseline triglyceride-glucose index and association with predicted 10-year cardiovascular disease risk among type 2 diabetes patients in Thailand. Sci Rep. 2023, 13:12960. 10.1038\/s41598-023-40299-y","journal-title":"Sci Rep"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02890-7","article-title":"Does diabetes status modify the association between the triglyceride-glucose index and major adverse cardiovascular events in patients with coronary heart disease? A systematic review and meta-analysis of longitudinal cohort studies","volume":"24","author":"Xu S","year":"2025","unstructured":"Xu S, Zhang Z, Li J, Ding Y, Chen Y, Zhou Y, Hu S. Does diabetes status modify the association between the triglyceride-glucose index and major adverse cardiovascular events in patients with coronary heart disease? A systematic review and meta-analysis of longitudinal cohort studies. Cardiovasc Diabetol. 2025, 24:317. 10.1186\/s12933-025-02890-7","journal-title":"Cardiovasc Diabetol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02937-9","article-title":"Triglyceride glucose index in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study","volume":"24","author":"Hu S","year":"2025","unstructured":"Hu S, Yan H, Sun Y, Wang D, Zeng H, Cui G. Triglyceride glucose index in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study. Cardiovasc Diabetol. 2025, 24:380. 10.1186\/s12933-025-02937-9","journal-title":"Cardiovasc Diabetol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02873-8","article-title":"Triglyceride glucose-weight-adjusted waist index as a cardiovascular mortality predictor: incremental value beyond the establishment of TyG-related indices","volume":"24","author":"Qiu J","year":"2025","unstructured":"Qiu J, Li J, Xu S, et al.. Triglyceride glucose-weight-adjusted waist index as a cardiovascular mortality predictor: incremental value beyond the establishment of TyG-related indices. Cardiovasc Diabetol. 2025, 24:306. 10.1186\/s12933-025-02873-8","journal-title":"Cardiovasc Diabetol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-024-02259-2","article-title":"Correlation between the triglyceride-glucose index and left ventricular global longitudinal strain in patients with chronic heart failure: a cross-sectional study","volume":"23","author":"Zhang S","year":"2024","unstructured":"Zhang S, Liu Y, Liu F, et al.. Correlation between the triglyceride-glucose index and left ventricular global longitudinal strain in patients with chronic heart failure: a cross-sectional study. Cardiovasc Diabetol. 2024, 23:182. 10.1186\/s12933-024-02259-2","journal-title":"Cardiovasc Diabetol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2025.1463647","article-title":"A meta-analysis of the prognostic value of the TyG index in heart failure","volume":"16","author":"Cai Y","year":"2025","unstructured":"Cai Y, Yang M, Ma S, Zhang J, Huang B, Yu B. A meta-analysis of the prognostic value of the TyG index in heart failure. Front Endocrinol. 2025, 16:1463647. 10.3389\/fendo.2025.1463647","journal-title":"Front Endocrinol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"Ponikowski P","year":"2016","unstructured":"Ponikowski P, Voors AA, Anker SD, et al.. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2016, 37:2129-200. 10.1093\/eurheartj\/ehw128","journal-title":"Eur Heart J"},{"key":"ref12","article-title":"The American Diabetes Association Releases \u201cStandards of Care in Diabetes\u20142026\u201d","author":"American Diabetes Association","year":"2025","unstructured":"American Diabetes Association. The American Diabetes Association Releases \u201cStandards of Care in Diabetes\u20142026\u201d. American Diabetes Association, Arlington, VA; 2025."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.704462","article-title":"Triglyceride-glucose index and extracellular volume fraction in patients with heart failure","volume":"8","author":"Yang S","year":"2021","unstructured":"Yang S, Du Y, Liu Z, Zhang R, Lin X, Ouyang Y, Chen H. Triglyceride-glucose index and extracellular volume fraction in patients with heart failure. Front Cardiovasc Med. 2021, 8:704462. 10.3389\/fcvm.2021.704462","journal-title":"Front Cardiovasc Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-018-0488-z","article-title":"Validity of triglyceride-glucose index as an indicator for metabolic syndrome in children and adolescents: the CASPIAN-V study","volume":"23","author":"Angoorani P","year":"2018","unstructured":"Angoorani P, Heshmat R, Ejtahed HS, et al.. Validity of triglyceride-glucose index as an indicator for metabolic syndrome in children and adolescents: the CASPIAN-V study. Eat Weight Disord. 2018, 23:877-83. 10.1007\/s40519-018-0488-z","journal-title":"Eat Weight Disord"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6891537","article-title":"The triglyceride\u2010glucose index predicts coronary artery disease severity and cardiovascular outcomes in patients with non\u2010ST\u2010segment elevation acute coronary syndrome","volume":"2019","author":"Mao Q","year":"2019","unstructured":"Mao Q, Zhou D, Li Y, Wang Y, Xu SC, Zhao XH. The triglyceride\u2010glucose index predicts coronary artery disease severity and cardiovascular outcomes in patients with non\u2010ST\u2010segment elevation acute coronary syndrome. Dis Markers. 2019, 2019:1-11. 10.1155\/2019\/6891537","journal-title":"Dis Markers"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0198144","article-title":"Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease","volume":"13","author":"Ramchand J","year":"2018","unstructured":"Ramchand J, Patel SK, Srivastava PM, Farouque O, Burrell LM. Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease. PLoS One. 2018, 13:0198144. 10.1371\/journal.pone.0198144","journal-title":"PLoS One"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-023-02060-7","article-title":"Prognostic value of triglyceride-glucose index in patients with chronic coronary syndrome undergoing percutaneous coronary intervention","volume":"22","author":"Tao S","year":"2023","unstructured":"Tao S, Yu L, Li J, et al.. Prognostic value of triglyceride-glucose index in patients with chronic coronary syndrome undergoing percutaneous coronary intervention. Cardiovasc Diabetol. 2023, 22:322. 10.1186\/s12933-023-02060-7","journal-title":"Cardiovasc Diabetol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-023-02018-9","article-title":"Association between the triglyceride-glucose index and 1-year major adverse cardiovascular events in patients with coronary heart disease and hypertension","volume":"22","author":"Tao S","year":"2023","unstructured":"Tao S, Yu L, Li J, et al.. Association between the triglyceride-glucose index and 1-year major adverse cardiovascular events in patients with coronary heart disease and hypertension. Cardiovasc Diabetol. 2023, 22:305. 10.1186\/s12933-023-02018-9","journal-title":"Cardiovasc Diabetol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/460054-predictive-value-of-the-triglyceride-glucose-index-tyg-index-for-major-cardiac-events-in-patients-with-chronic-heart-failure-and-type-2-diabetes-a-prospective-observational-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T04:09:52Z","timestamp":1770610192000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/460054-predictive-value-of-the-triglyceride-glucose-index-tyg-index-for-major-cardiac-events-in-patients-with-chronic-heart-failure-and-type-2-diabetes-a-prospective-observational-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,8]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.103232","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,8]]}}}