{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T16:04:57Z","timestamp":1770825897882,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,11]]},"DOI":"10.7759\/cureus.103422","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:09:16Z","timestamp":1770822556000},"source":"Crossref","is-referenced-by-count":0,"title":["Splenic Rupture Due to Metastasis of Breast Cancer: A Report of a Rare Case and Focused Literature Review"],"prefix":"10.7759","author":[{"given":"Kayra","family":"Cangoz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammed Bahadir","family":"Avci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isil","family":"Karabulut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firathan","family":"Sarialtin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Atas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015016","article-title":"Synchronous isolated splenic metastasis from cancer of hepatic flexure of colon: a case report","volume":"98","author":"Zhao H","year":"2019","unstructured":"Zhao H, Zhong W, Chen D, Cheng X. Synchronous isolated splenic metastasis from cancer of hepatic flexure of colon: a case report. Medicine (Baltimore). 2019, 98:e15016. 10.1097\/MD.0000000000015016","journal-title":"Medicine (Baltimore)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1177\/10732748241310578","article-title":"Clinicopathological features and prognoses of patients with splenic metastases from breast cancer: a single-centre, retrospective study","volume":"32","author":"Xie X","year":"2025","unstructured":"Xie X, Ma M, Bai X, et al.. Clinicopathological features and prognoses of patients with splenic metastases from breast cancer: a single-centre, retrospective study. Cancer Control. 2025, 32:10732748241310578. 10.1177\/10732748241310578","journal-title":"Cancer Control"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v8.i15.3320","article-title":"Isolated metachronous splenic multiple metastases after colon cancer surgery: a case report and literature review","volume":"8","author":"Hu L","year":"2020","unstructured":"Hu L, Zhu JY, Fang L, Yu XC, Yan ZL. Isolated metachronous splenic multiple metastases after colon cancer surgery: a case report and literature review. World J Clin Cases. 2020, 8:3320-8. 10.12998\/wjcc.v8.i15.3320","journal-title":"World J Clin Cases"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-017-9992-z","article-title":"Isolated metachronous splenic metastasis from colon cancer: possible explanations for this rare entity","volume":"50","author":"Rizzo F","year":"2019","unstructured":"Rizzo F, Calamia S, Mingoia G, Fulfaro F, Grassi N, Cipolla C. Isolated metachronous splenic metastasis from colon cancer: possible explanations for this rare entity. J Gastrointest Cancer. 2019, 50:143-6. 10.1007\/s12029-017-9992-z","journal-title":"J Gastrointest Cancer"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjaf751","article-title":"Isolated splenic metastasis presenting at diagnosis of HER2-positive de novo metastatic breast cancer: a case report","volume":"2025","author":"Yoshioka M","year":"2025","unstructured":"Yoshioka M, Shimoda M, Abe K, et al.. Isolated splenic metastasis presenting at diagnosis of HER2-positive de novo metastatic breast cancer: a case report. J Surg Case Rep. 2025, 2025:rjaf751. 10.1093\/jscr\/rjaf751","journal-title":"J Surg Case Rep"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-223453","article-title":"Splenectomy for breast carcinoma diffusely metastatic to the spleen presenting as severe transfusion-dependent anaemia and thrombocytopaenia","volume":"11","author":"Hasadia R","year":"2018","unstructured":"Hasadia R, Kazarin O, Sofer O, Shulman K, Troitsa A, Alfici R, Ashkenazi I. Splenectomy for breast carcinoma diffusely metastatic to the spleen presenting as severe transfusion-dependent anaemia and thrombocytopaenia. BMJ Case Rep. 2018, 11:10.1136\/bcr-2017-223453","journal-title":"BMJ Case Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/omcr\/omx069","article-title":"Breast cancer metastasis to the spleen: a case report and literature review","volume":"2017","author":"El Fadli M","year":"2017","unstructured":"El Fadli M, Kerrou K, Alaoui Mhamdi H, et al.. Breast cancer metastasis to the spleen: a case report and literature review. Oxf Med Case Reports. 2017, 2017:omx069. 10.1093\/omcr\/omx069","journal-title":"Oxf Med Case Reports"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.5798\/diclemedj.0921.2012.01.0108","article-title":"Approach to hypersplenism due to splenic metastasis of breast cancer: a case report","volume":"39","author":"K\u00fc\u00e7\u00fck\u00f6ner M","year":"2012","unstructured":"K\u00fc\u00e7\u00fck\u00f6ner M, Kaplan MA, \u0130nal A, et al.. Approach to hypersplenism due to splenic metastasis of breast cancer: a case report. Dicle Med J. 2012, 39:117-20. 10.5798\/diclemedj.0921.2012.01.0108","journal-title":"Dicle Med J"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.5858\/2007-131-965-SMCPDD","article-title":"Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis","volume":"131","author":"Comp\u00e9rat E","year":"2007","unstructured":"Comp\u00e9rat E, Bardier-Dupas A, Camparo P, Capron F, Charlotte F. Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis. Arch Pathol Lab Med. 2007, 131:965-9. 10.5858\/2007-131-965-SMCPDD","journal-title":"Arch Pathol Lab Med"},{"key":"ref10","article-title":"Splenic metastases. Frequencies and patterns","volume":"82","author":"Berge T","year":"1974","unstructured":"Berge T. Splenic metastases. Frequencies and patterns. Acta Pathol Microbiol Scand A. 1974, 82:499-506.","journal-title":"Acta Pathol Microbiol Scand A"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010601)91:11<2001::aid-cncr1225>3.0.co;2-3","article-title":"The spleen as a diagnostic specimen: a review of 10 years' experience at two tertiary care institutions","volume":"91","author":"Kraus MD","year":"2001","unstructured":"Kraus MD, Fleming MD, Vonderheide RH. The spleen as a diagnostic specimen: a review of 10 years' experience at two tertiary care institutions. Cancer. 2001, 91:2001-9. 10.1002\/1097-0142(20010601)91:11&lt;2001::aid-cncr1225&gt;3.0.co;2-3","journal-title":"Cancer"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1997.16.11.743","article-title":"Isolated splenic metastases","volume":"16","author":"Ishida H","year":"1997","unstructured":"Ishida H, Konno K, Ishida J, et al.. Isolated splenic metastases. J Ultrasound Med. 1997, 16:743-9. 10.7863\/jum.1997.16.11.743","journal-title":"J Ultrasound Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/cas.16396","article-title":"Micropapillary structure: a natural tumor collective invasion model with enhanced stem-like properties","volume":"116","author":"Li S","year":"2025","unstructured":"Li S, Gao S, Qin L, et al.. Micropapillary structure: a natural tumor collective invasion model with enhanced stem-like properties. Cancer Sci. 2025, 116:308-21. 10.1111\/cas.16396","journal-title":"Cancer Sci"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1177\/03000605231195468","article-title":"Identifying the optimal cutoff point of Ki-67 in breast cancer: a single-center experience","volume":"51","author":"Li W","year":"2023","unstructured":"Li W, Lu N, Chen C, Lu X. Identifying the optimal cutoff point of Ki-67 in breast cancer: a single-center experience. J Int Med Res. 2023, 51:3000605231195468. 10.1177\/03000605231195468","journal-title":"J Int Med Res"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000488764","article-title":"Ipsilateral breast tumor reappearance and contralateral breast cancer after primary breast cancer treatment: a comprehensive retrospective study of 15,168 patients","volume":"95","author":"Corso G","year":"2018","unstructured":"Corso G, Maisonneuve P, Santomauro GI, et al.. Ipsilateral breast tumor reappearance and contralateral breast cancer after primary breast cancer treatment: a comprehensive retrospective study of 15,168 patients. Oncology. 2018, 95:147-55. 10.1159\/000488764","journal-title":"Oncology"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/456232-splenic-rupture-due-to-metastasis-of-breast-cancer-a-report-of-a-rare-case-and-focused-literature-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:09:20Z","timestamp":1770822560000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/456232-splenic-rupture-due-to-metastasis-of-breast-cancer-a-report-of-a-rare-case-and-focused-literature-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,11]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.103422","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,11]]}}}