{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T20:11:28Z","timestamp":1772741488586,"version":"3.50.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,5]]},"DOI":"10.7759\/cureus.104725","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T19:35:07Z","timestamp":1772739307000},"source":"Crossref","is-referenced-by-count":0,"title":["Brainstem Hemorrhage Following Eclampsia and HELLP Syndrome: A Case Report of an Unusual Neuro-Obstetric Complication"],"prefix":"10.7759","author":[{"given":"Marouane","family":"Jidal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youssra","family":"Kramchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achraf","family":"Jeddab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Slimani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilyass","family":"Hmadate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayoub","family":"Boubekri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rida","family":"Touab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si mohammed","family":"Andaloussi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil","family":"Mounir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelhamid","family":"Jaafari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-021-00958-z","article-title":"Neurology of preeclampsia and related disorders: an update in neuro-obstetrics","volume":"25","author":"Miller EC","year":"2021","unstructured":"Miller EC, Vollbracht S. Neurology of preeclampsia and related disorders: an update in neuro-obstetrics. Curr Pain Headache Rep. 2021, 25:40. 10.1007\/s11916-021-00958-z","journal-title":"Curr Pain Headache Rep"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59101707","article-title":"Stroke vs. Preeclampsia: dangerous liaisons of hypertension and pregnancy","volume":"59","author":"Lackovic M","year":"2023","unstructured":"Lackovic M, Nikolic D, Jankovic M, Rovcanin M, Mihajlovic S. Stroke vs. Preeclampsia: dangerous liaisons of hypertension and pregnancy. Medicina (Kaunas). 2023, 59:10.3390\/medicina59101707","journal-title":"Medicina (Kaunas)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/2396987317706600","article-title":"The incidence of first stroke in and around pregnancy: a population-based cohort study from Sweden","volume":"2","author":"Ban L","year":"2017","unstructured":"Ban L, Abdul Sultan A, Stephansson O, et al.. The incidence of first stroke in and around pregnancy: a population-based cohort study from Sweden. Eur Stroke J. 2017, 2:250-56. 10.1177\/2396987317706600","journal-title":"Eur Stroke J"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000172428.78411.b0","article-title":"Incidence and risk factors for stroke in pregnancy and the puerperium","volume":"106","author":"James AH","year":"2005","unstructured":"James AH, Bushnell CD, Jamison MG, Myers ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstet Gynecol. 2005, 106:509-16. 10.1097\/01.AOG.0000172428.78411.b0","journal-title":"Obstet Gynecol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000200944","article-title":"Incidence and time trends of pregnancy-related stroke between 2010 and 2018: the nationwide Conception study","volume":"99","author":"Martin A","year":"2022","unstructured":"Martin A, Lailler G, B\u00e9jot Y, et al.. Incidence and time trends of pregnancy-related stroke between 2010 and 2018: the nationwide Conception study. Neurology. 2022, 99:e1598-608. 10.1212\/WNL.0000000000200944","journal-title":"Neurology"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.034032","article-title":"Primary and secondary intracerebral hemorrhage in pregnant and nonpregnant young adults by smash-up criteria","volume":"13","author":"Sariyeva M","year":"2024","unstructured":"Sariyeva M, Haghighi N, Mitchell A, et al.. Primary and secondary intracerebral hemorrhage in pregnant and nonpregnant young adults by smash-up criteria. J Am Heart Assoc. 2024, 13:e034032. 10.1161\/JAHA.123.034032","journal-title":"J Am Heart Assoc"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-015-0575-8","article-title":"Cerebrovascular dysfunction in preeclamptic pregnancies","volume":"17","author":"Hammer ES","year":"2015","unstructured":"Hammer ES, Cipolla MJ. Cerebrovascular dysfunction in preeclamptic pregnancies. Curr Hypertens Rep. 2015, 17:64. 10.1007\/s11906-015-0575-8","journal-title":"Curr Hypertens Rep"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-019-0961-8","article-title":"Pathophysiology of cerebral vascular dysfunction in pregnancy-induced hypertension","volume":"21","author":"Younes ST","year":"2019","unstructured":"Younes ST, Ryan MJ. Pathophysiology of cerebral vascular dysfunction in pregnancy-induced hypertension. Curr Hypertens Rep. 2019, 21:52. 10.1007\/s11906-019-0961-8","journal-title":"Curr Hypertens Rep"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2021.03.017","article-title":"Cerebral perfusion pressure and autoregulation in eclampsia-a case control study","volume":"225","author":"Bergman L","year":"2021","unstructured":"Bergman L, Cluver C, Carlberg N, Belfort M, Tolcher MC, Panerai RB, van Veen T. Cerebral perfusion pressure and autoregulation in eclampsia-a case control study. Am J Obstet Gynecol. 2021, 225:185.e1-9. 10.1016\/j.ajog.2021.03.017","journal-title":"Am J Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-9-8","article-title":"The HELLP syndrome: clinical issues and management. A Review","volume":"9","author":"Haram K","year":"2009","unstructured":"Haram K, Svendsen E, Abildgaard U. The HELLP syndrome: clinical issues and management. A Review. BMC Pregnancy Childbirth. 2009, 9:8. 10.1186\/1471-2393-9-8","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1258\/om.2012.110030","article-title":"Beware of delayed severe brain swelling after intracerebral haematoma in HELLP syndrome","volume":"6","author":"Gioffr\u00e8 G","year":"2013","unstructured":"Gioffr\u00e8 G, Bodkin PA, Labram EK, Shetty A. Beware of delayed severe brain swelling after intracerebral haematoma in HELLP syndrome. Obstet Med. 2013, 6:129-31. 10.1258\/om.2012.110030","journal-title":"Obstet Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.727962","article-title":"Primary brainstem hemorrhage: a review of prognostic factors and surgical management","volume":"12","author":"Chen D","year":"2021","unstructured":"Chen D, Tang Y, Nie H, et al.. Primary brainstem hemorrhage: a review of prognostic factors and surgical management. Front Neurol. 2021, 12:727962. 10.3389\/fneur.2021.727962","journal-title":"Front Neurol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003891","article-title":"Gestational hypertension and preeclampsia: acog practice bulletin, number 222","volume":"135","year":"2020","unstructured":"Gestational hypertension and preeclampsia. acog practice bulletin, number 222. Obstet Gynecol. 2020, 135:e237-60. 10.1097\/AOG.0000000000003891","journal-title":"Obstet Gynecol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e31829bdc5c","article-title":"A proposal for a new method of evaluation of the newborn infant","volume":"120","author":"Apgar V","year":"2015","unstructured":"Apgar V. A proposal for a new method of evaluation of the newborn infant. Anesth Analg. 2015, 120:1056-59. 10.1213\/ANE.0b013e31829bdc5c","journal-title":"Anesth Analg"},{"key":"ref15","article-title":"Kidney Disease: Improving Global Outcomes (KDIGO)","volume":"2","author":"Acute Kidney Injury Work Group","year":"2012","unstructured":"Acute Kidney Injury Work Group. Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int Suppl. 2012, 2:1-138.","journal-title":"Kidney Int Suppl"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20611","article-title":"Validation of a new coma scale: The FOUR score","volume":"58","author":"Wijdicks EF","year":"2005","unstructured":"Wijdicks EF, Bamlet WR, Maramattom BV, Manno EM, McClelland RL. Validation of a new coma scale: The FOUR score. Ann Neurol. 2005, 58:585-93. 10.1002\/ana.20611","journal-title":"Ann Neurol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.02.033","article-title":"The JFK Coma Recovery Scale-Revised: measurement characteristics and diagnostic utility","volume":"85","author":"Giacino JT","year":"2004","unstructured":"Giacino JT, Kalmar K, Whyte J. The JFK Coma Recovery Scale-Revised: measurement characteristics and diagnostic utility. Arch Phys Med Rehabil. 2004, 85:2020-29. 10.1016\/j.apmr.2004.02.033","journal-title":"Arch Phys Med Rehabil"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/1747493017723271","article-title":"The incidence of pregnancy-related stroke: a systematic review and meta-analysis","volume":"12","author":"Swartz RH","year":"2017","unstructured":"Swartz RH, Cayley ML, Foley N, et al.. The incidence of pregnancy-related stroke: a systematic review and meta-analysis. Int J Stroke. 2017, 12:687-97. 10.1177\/1747493017723271","journal-title":"Int J Stroke"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.018416","article-title":"Preeclampsia: association with posterior reversible encephalopathy syndrome and stroke","volume":"49","author":"McDermott M","year":"2018","unstructured":"McDermott M, Miller EC, Rundek T, Hurn PD, Bushnell CD. Preeclampsia: association with posterior reversible encephalopathy syndrome and stroke. Stroke. 2018, 49:524-30. 10.1161\/STROKEAHA.117.018416","journal-title":"Stroke"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7772","article-title":"Life-threatening pontine hemorrhage secondary to HELLP syndrome","volume":"11","author":"Ali S","year":"2023","unstructured":"Ali S, Fazal SA, Monawwer SA, Anan M. Life-threatening pontine hemorrhage secondary to HELLP syndrome. Clin Case Rep. 2023, 11:e7772. 10.1002\/ccr3.7772","journal-title":"Clin Case Rep"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2017.27.266.12288","article-title":"Haemorrhagic stroke of the brainstem secondary to postpartum eclampsia: about a case and literature review","volume":"27","author":"Ennaqui K","year":"2017","unstructured":"Ennaqui K, Makayssi A, Boufettal H, Samouh N. Haemorrhagic stroke of the brainstem secondary to postpartum eclampsia: about a case and literature review. Pan Afr Med J. 2017, 27:266. 10.11604\/pamj.2017.27.266.12288","journal-title":"Pan Afr Med J"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.7.1150","article-title":"Lethal pontine hemorrhage in postpartum syndrome of hemolysis, elevated liver enzyme levels, and low platelet count","volume":"62","author":"Zeidman LA","year":"2005","unstructured":"Zeidman LA, Videnovic A, Bernstein LP, Pellar CA. Lethal pontine hemorrhage in postpartum syndrome of hemolysis, elevated liver enzyme levels, and low platelet count. Arch Neurol. 2005, 62:1150-53. 10.1001\/archneur.62.7.1150","journal-title":"Arch Neurol"},{"key":"ref23","article-title":"Pontine hematoma associated with eclampsia: case report","volume":"7","author":"\u00c7obanassis A","year":"2012","unstructured":"\u00c7obanassis A, Bebekassoc N, \u00c7oban O, et al.. Pontine hematoma associated with eclampsia: case report. Turkiye Klinikleri J Neur. 2012, 7:36-40.","journal-title":"Turkiye Klinikleri J Neur"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1080\/01658107.2024.2303708","article-title":"Millard-Gubler syndrome in a patient with preeclampsia. Case report and review of combined intra- and extra-axial facial and abducens nerve injuries","volume":"48","author":"S\u00e1nchez Moscoso PA","year":"2024","unstructured":"S\u00e1nchez Moscoso PA, Bautista Torres AM, Bonilla-Escobar FJ, Salamanca Libreros OF. Millard-Gubler syndrome in a patient with preeclampsia. Case report and review of combined intra- and extra-axial facial and abducens nerve injuries. Neuroophthalmology. 2024, 48:294-98. 10.1080\/01658107.2024.2303708","journal-title":"Neuroophthalmology"},{"key":"ref25","article-title":"Pontine hemorrhage after spinal anesthesia in a pregnant woman with HELLP syndrome","volume":"3","author":"Yao H-Y","year":"2018","unstructured":"Yao H-Y, Chen Y-M. Pontine hemorrhage after spinal anesthesia in a pregnant woman with HELLP syndrome. Intensive Care Med. 2018, 3:44-48.","journal-title":"Intensive Care Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/466172-brainstem-hemorrhage-following-eclampsia-and-hellp-syndrome-a-case-report-of-an-unusual-neuro-obstetric-complication","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T19:35:08Z","timestamp":1772739308000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/466172-brainstem-hemorrhage-following-eclampsia-and-hellp-syndrome-a-case-report-of-an-unusual-neuro-obstetric-complication"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,5]]},"references-count":25,"URL":"https:\/\/doi.org\/10.7759\/cureus.104725","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,5]]}}}