{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T01:34:39Z","timestamp":1773106479370,"version":"3.50.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,9]]},"DOI":"10.7759\/cureus.104914","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T14:09:11Z","timestamp":1773065351000},"source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Plaque Imaging Techniques for Calcified Lesions Using MRI Termed Modified Liver Acquisition With Volume Acceleration (mLAVA)"],"prefix":"10.7759","author":[{"given":"Yoshiaki","family":"Kitazawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyofumi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kisaki","family":"Amemiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Morita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroharu","family":"Kataoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000189204","article-title":"Human carotid plaque calcification and vulnerability. Relationship between degree of plaque calcification, fibrous cap inflammatory gene expression and symptomatology","volume":"27","author":"Wahlgren CM","year":"2009","unstructured":"Wahlgren CM, Zheng W, Shaalan W, Tang J, Bassiouny HS. Human carotid plaque calcification and vulnerability. Relationship between degree of plaque calcification, fibrous cap inflammatory gene expression and symptomatology. Cerebrovasc Dis. 2009, 27:193-200. 10.1159\/000189204","journal-title":"Cerebrovasc Dis"},{"key":"ref2","article-title":"The correlation between calcification in carotid plaque and stroke: calcification may be a risk factor for stroke","volume":"12","author":"Kan Y","year":"2019","unstructured":"Kan Y, He W, Ning B, Li H, Wei S, Yu T. The correlation between calcification in carotid plaque and stroke: calcification may be a risk factor for stroke. Int J Clin Exp Pathol. 2019, 12:750-8.","journal-title":"Int J Clin Exp Pathol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A7443","article-title":"Reassessing the carotid artery plaque \"rim sign\" on CTA: a new analysis with histopathologic confirmation","volume":"43","author":"Benson JC","year":"2022","unstructured":"Benson JC, Nardi V, Madhavan AA, et al.. Reassessing the carotid artery plaque \"rim sign\" on CTA: a new analysis with histopathologic confirmation. AJNR Am J Neuroradiol. 2022, 43:429-34. 10.3174\/ajnr.A7443","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-024-03788-9","article-title":"Prevalence and clinical implications of calcification in internal carotid artery stenosis: a retrospective study","volume":"24","author":"Fu F","year":"2024","unstructured":"Fu F, Liu X, Zhang R, et al.. Prevalence and clinical implications of calcification in internal carotid artery stenosis: a retrospective study. BMC Neurol. 2024, 24:279. 10.1186\/s12883-024-03788-9","journal-title":"BMC Neurol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25320","article-title":"Projection MR imaging of peripheral arterial calcifications","volume":"73","author":"Edelman RR","year":"2015","unstructured":"Edelman RR, Flanagan O, Grodzki D, Giri S, Gupta N, Koktzoglou I. Projection MR imaging of peripheral arterial calcifications. Magn Reson Med. 2015, 73:1939-45. 10.1002\/mrm.25320","journal-title":"Magn Reson Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009030287","article-title":"Carotid endarterectomy benefits patients with CKD and symptomatic high-grade stenosis","volume":"21","author":"Mathew A","year":"2010","unstructured":"Mathew A, Eliasziw M, Devereaux PJ, Merino JG, Barnett HJ, Garg AX. Carotid endarterectomy benefits patients with CKD and symptomatic high-grade stenosis. J Am Soc Nephrol. 2010, 21:145-52. 10.1681\/ASN.2009030287","journal-title":"J Am Soc Nephrol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21956","article-title":"Liver parenchymal enhancement of hepatocyte-phase images in Gd-EOB-DTPA-enhanced MR imaging: which biological markers of the liver function affect the enhancement?","volume":"30","author":"Motosugi U","year":"2009","unstructured":"Motosugi U, Ichikawa T, Sou H, Sano K, Tominaga L, Kitamura T, Araki T. Liver parenchymal enhancement of hepatocyte-phase images in Gd-EOB-DTPA-enhanced MR imaging: which biological markers of the liver function affect the enhancement?. J Magn Reson Imaging. 2009, 30:1042-6. 10.1002\/jmri.21956","journal-title":"J Magn Reson Imaging"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.22.6.711","article-title":"North American Symptomatic Carotid Endarterectomy Trial. Methods, patient characteristics, and progress","volume":"22","year":"1991","unstructured":"North American Symptomatic Carotid Endarterectomy Trial. Methods, patient characteristics, and progress. Stroke. 1991, 22.711-20. 10.1161\/01.str.22.6.711","journal-title":"Stroke"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.19.5.604","article-title":"Interobserver agreement for the assessment of handicap in stroke patients","volume":"19","author":"van Swieten JC","year":"1988","unstructured":"van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJ, van Gijn J. Interobserver agreement for the assessment of handicap in stroke patients. Stroke. 1988, 19:604-7. 10.1161\/01.str.19.5.604","journal-title":"Stroke"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.02.016","article-title":"Eruptive calcified nodules as a potential mechanism of acute coronary thrombosis and sudden death","volume":"77","author":"Torii S","year":"2021","unstructured":"Torii S, Sato Y, Otsuka F, et al.. Eruptive calcified nodules as a potential mechanism of acute coronary thrombosis and sudden death. J Am Coll Cardiol. 2021, 77:1599-611. 10.1016\/j.jacc.2021.02.016","journal-title":"J Am Coll Cardiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4765","article-title":"Prediction of carotid intraplaque hemorrhage using adventitial calcification and plaque thickness on CTA","volume":"37","author":"Eisenmenger LB","year":"2016","unstructured":"Eisenmenger LB, Aldred BW, Kim SE, et al.. Prediction of carotid intraplaque hemorrhage using adventitial calcification and plaque thickness on CTA. AJNR Am J Neuroradiol. 2016, 37:1496-503. 10.3174\/ajnr.A4765","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X231225463","article-title":"Risk factors for recurrent ischemic events in symptomatic carotid artery stenosis on CT angiography","volume":"29","author":"Tsutsui T","year":"2024","unstructured":"Tsutsui T, Yamada K, Ikedo T, et al.. Risk factors for recurrent ischemic events in symptomatic carotid artery stenosis on CT angiography. Vasc Med. 2024, 29:211-2. 10.1177\/1358863X231225463","journal-title":"Vasc Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.20.5.1262","article-title":"Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions","volume":"20","author":"Virmani R","year":"2000","unstructured":"Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 2000, 20:1262-75. 10.1161\/01.atv.20.5.1262","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.01.017","article-title":"Sex differences in coronary artery disease: pathological observations","volume":"239","author":"Yahagi K","year":"2015","unstructured":"Yahagi K, Davis HR, Arbustini E, Virmani R. Sex differences in coronary artery disease: pathological observations. Atherosclerosis. 2015, 239:260-7. 10.1016\/j.atherosclerosis.2015.01.017","journal-title":"Atherosclerosis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X251324159","article-title":"Pathological and clinical findings of calcified nodules in carotid artery stenosis: a study of 508 consecutive carotid endarterectomies","volume":"30","author":"Yamada K","year":"2025","unstructured":"Yamada K, Hatakeyama K, Amemiya K, et al.. Pathological and clinical findings of calcified nodules in carotid artery stenosis: a study of 508 consecutive carotid endarterectomies. Vasc Med. 2025, 30:485-7. 10.1177\/1358863X251324159","journal-title":"Vasc Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.03.009","article-title":"Impact of eruptive vs noneruptive calcified nodule morphology on acute and long-term outcomes after stenting","volume":"16","author":"Sato T","year":"2023","unstructured":"Sato T, Matsumura M, Yamamoto K, et al.. Impact of eruptive vs noneruptive calcified nodule morphology on acute and long-term outcomes after stenting. JACC Cardiovasc Interv. 2023, 16:1024-35. 10.1016\/j.jcin.2023.03.009","journal-title":"JACC Cardiovasc Interv"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2024.03.032","article-title":"Calcified nodule in percutaneous coronary intervention: therapeutic challenges","volume":"17","author":"Shin D","year":"2024","unstructured":"Shin D, Karimi Galougahi K, Spratt JC, et al.. Calcified nodule in percutaneous coronary intervention: therapeutic challenges. JACC Cardiovasc Interv. 2024, 17:1187-99. 10.1016\/j.jcin.2024.03.032","journal-title":"JACC Cardiovasc Interv"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.46233","article-title":"Difficulties in carotid artery stenting due to calcified nodules: a case report","volume":"15","author":"Sakurada K","year":"2023","unstructured":"Sakurada K, Yamada K, Amemiya K, Yamaguchi E, Kataoka H. Difficulties in carotid artery stenting due to calcified nodules: a case report. Cureus. 2023, 15:e46233. 10.7759\/cureus.46233","journal-title":"Cureus"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1088\/0952-4746\/28\/2\/R02","article-title":"New ICRP recommendations","volume":"28","author":"Wrixon AD","year":"2008","unstructured":"Wrixon AD. New ICRP recommendations. J Radiol Prot. 2008, 28:161-8. 10.1088\/0952-4746\/28\/2\/R02","journal-title":"J Radiol Prot"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/458152-evaluation-of-plaque-imaging-techniques-for-calcified-lesions-using-mri-termed-modified-liver-acquisition-with-volume-acceleration-mlava","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T14:09:12Z","timestamp":1773065352000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/458152-evaluation-of-plaque-imaging-techniques-for-calcified-lesions-using-mri-termed-modified-liver-acquisition-with-volume-acceleration-mlava"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,9]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.104914","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,9]]}}}