{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T01:34:08Z","timestamp":1778981648313,"version":"3.51.4"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,14]]},"DOI":"10.7759\/cureus.105227","type":"journal-article","created":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T15:20:38Z","timestamp":1773501638000},"source":"Crossref","is-referenced-by-count":2,"title":["Dilute Hyaluronic Acid for Lipoatrophy: Three Cases and Literature Review"],"prefix":"10.7759","author":[{"given":"Juliana M","family":"O'Reilly","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S","family":"Kirwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis","family":"Frantz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willis","family":"Lyford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5114\/pdia.2014.40971","article-title":"Acquired facial lipoatrophy: pathogenesis and therapeutic options","volume":"32","author":"Szczerkowska-Dobosz A","year":"2015","unstructured":"Szczerkowska-Dobosz A, Olszewska B, Lema\u0144ska M, Purzycka-Bohdan D, Nowicki R. Acquired facial lipoatrophy: pathogenesis and therapeutic options. Postepy Dermatol Alergol. 2015, 32:127-33. 10.5114\/pdia.2014.40971","journal-title":"Postepy Dermatol Alergol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0b013e3181cc85b0","article-title":"Large particle hyaluronic acid gel for the treatment of lower eyelid retraction associated with radiation-induced lipoatrophy","volume":"26","author":"Peckinpaugh JL","year":"2010","unstructured":"Peckinpaugh JL, Reddy HS, Tower RN. Large particle hyaluronic acid gel for the treatment of lower eyelid retraction associated with radiation-induced lipoatrophy. Ophthalmic Plast Reconstr Surg. 2010, 26:377-9. 10.1097\/IOP.0b013e3181cc85b0","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2021.05.013","article-title":"Lipoatrophia semicircularis: clinical study and follow-up of 76 cases in Madrid, Spain. Classification proposal","volume":"113","author":"Bru-Gorraiz FJ","year":"2022","unstructured":"Bru-Gorraiz FJ, Comuni\u00f3n-Artieda A, Bordel-Nieto I, Martin-Gorgojo A. Lipoatrophia semicircularis: clinical study and follow-up of 76 cases in Madrid, Spain. Classification proposal. Actas Dermosifiliogr. 2022, 113:15-21. 10.1016\/j.ad.2021.05.013","journal-title":"Actas Dermosifiliogr"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-242964","article-title":"Acquired localised lipoatrophy secondary to transgluteal drainage","volume":"14","author":"Hamp A","year":"2021","unstructured":"Hamp A, Anderson J, Bal A, Hansen N. Acquired localised lipoatrophy secondary to transgluteal drainage. BMJ Case Rep. 2021, 14:10.1136\/bcr-2021-242964","journal-title":"BMJ Case Rep"},{"key":"ref5","article-title":"Poly-L-lactic acid for the treatment of trauma-induced facial lipoatrophy and asymmetry","volume":"81","author":"Rendon MI","year":"2008","unstructured":"Rendon MI, Keeling J. Poly-L-lactic acid for the treatment of trauma-induced facial lipoatrophy and asymmetry. Cutis. 2008, 81:218-22.","journal-title":"Cutis"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.131880","article-title":"The rheology of injectable hyaluronic acid hydrogels used as facial fillers: a review","volume":"268","author":"Perera GG","year":"2024","unstructured":"Perera GG, Argenta DF, Caon T. The rheology of injectable hyaluronic acid hydrogels used as facial fillers: a review. Int J Biol Macromol. 2024, 268:131880. 10.1016\/j.ijbiomac.2024.131880","journal-title":"Int J Biol Macromol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/ski2.290","article-title":"Square technique - a treatment for cellulite with large size particle hyaluronic acid","volume":"4","author":"de Matos Louren\u00e7o L","year":"2024","unstructured":"de Matos Louren\u00e7o L, Colla LA, Ortiz de Noronha MG, Izzo TR, Sigrist R. Square technique - a treatment for cellulite with large size particle hyaluronic acid. Skin Health Dis. 2024, 4:e290. 10.1002\/ski2.290","journal-title":"Skin Health Dis"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13454","article-title":"Long-term effectiveness of a hyaluronic acid soft tissue filler in patients with facial lipoatrophy, morphological asymmetry, or debilitating scars","volume":"19","author":"Grablowitz D","year":"2020","unstructured":"Grablowitz D, Ivezic-Schoenfeld Z, Federspiel IG, Gehl B, Kopera D, Prinz M. Long-term effectiveness of a hyaluronic acid soft tissue filler in patients with facial lipoatrophy, morphological asymmetry, or debilitating scars. J Cosmet Dermatol. 2020, 19:2536-41. 10.1111\/jocd.13454","journal-title":"J Cosmet Dermatol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13813","article-title":"Saline in dermatology: a literature review","volume":"20","author":"El-Amawy HS","year":"2021","unstructured":"El-Amawy HS, Sarsik SM. Saline in dermatology: a literature review. J Cosmet Dermatol. 2021, 20:2040-51. 10.1111\/jocd.13813","journal-title":"J Cosmet Dermatol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2022.37.e37","article-title":"Treatment of human immunodeficiency virus-associated facial lipoatrophy with hyaluronic acid filler mixed with micronized cross-linked acellular dermal matrix","volume":"37","author":"Kim J","year":"2022","unstructured":"Kim J, Song SY, Lee SG, Choi S, Lee YI, Choi JY, Lee JH. Treatment of human immunodeficiency virus-associated facial lipoatrophy with hyaluronic acid filler mixed with micronized cross-linked acellular dermal matrix. J Korean Med Sci. 2022, 37:e37. 10.3346\/jkms.2022.37.e37","journal-title":"J Korean Med Sci"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-011-9771-3","article-title":"High-density hyaluronic acid for the treatment of HIV-related facial lipoatrophy","volume":"36","author":"Pignatti M","year":"2012","unstructured":"Pignatti M, Pedone A, Baccarani A, Guaraldi G, Orlando G, Lombardi M, De Santis G. High-density hyaluronic acid for the treatment of HIV-related facial lipoatrophy. Aesthetic Plast Surg. 2012, 36:180-5. 10.1007\/s00266-011-9771-3","journal-title":"Aesthetic Plast Surg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-023-03465-1","article-title":"Adverse events associated with hyaluronic acid filler injection for non-surgical facial aesthetics: a systematic review of high level of evidence studies","volume":"48","author":"Kyriazidis I","year":"2024","unstructured":"Kyriazidis I, Spyropoulou GA, Zambacos G, et al.. Adverse events associated with hyaluronic acid filler injection for non-surgical facial aesthetics: a systematic review of high level of evidence studies. Aesthetic Plast Surg. 2024, 48:719-41. 10.1007\/s00266-023-03465-1","journal-title":"Aesthetic Plast Surg"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002184","article-title":"Global Aesthetics consensus: avoidance and management of complications from hyaluronic acid fillers-evidence- and opinion-based review and consensus recommendations","volume":"137","author":"Signorini M","year":"2016","unstructured":"Signorini M, Liew S, Sundaram H, et al.. Global Aesthetics consensus: avoidance and management of complications from hyaluronic acid fillers-evidence- and opinion-based review and consensus recommendations. Plast Reconstr Surg. 2016, 137:961e-71e. 10.1097\/PRS.0000000000002184","journal-title":"Plast Reconstr Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002208","article-title":"Analysis of U.S. Food and Drug Administration data on soft-tissue filler complications","volume":"46","author":"Ortiz AE","year":"2020","unstructured":"Ortiz AE, Ahluwalia J, Song SS, Avram MM. Analysis of U.S. Food and Drug Administration data on soft-tissue filler complications. Dermatol Surg. 2020, 46:958-61. 10.1097\/DSS.0000000000002208","journal-title":"Dermatol Surg"},{"key":"ref15","article-title":"Should hyaluronic acid fillers be diluted?","volume":"13","author":"Smith KJ","year":"2014","unstructured":"Smith KJ. Should hyaluronic acid fillers be diluted?. J Drugs Dermatol. 2014, 13:1437-8.","journal-title":"J Drugs Dermatol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/1090820X10391214","article-title":"A technique for filling the temples with highly diluted hyaluronic acid: the \"dilution solution\"","volume":"31","author":"Lambros V","year":"2011","unstructured":"Lambros V. A technique for filling the temples with highly diluted hyaluronic acid: the \"dilution solution\". Aesthet Surg J. 2011, 31:89-94. 10.1177\/1090820X10391214","journal-title":"Aesthet Surg J"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/427256-dilute-hyaluronic-acid-for-lipoatrophy-three-cases-and-literature-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T15:20:38Z","timestamp":1773501638000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/427256-dilute-hyaluronic-acid-for-lipoatrophy-three-cases-and-literature-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,14]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.105227","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,14]]}}}