{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:51:33Z","timestamp":1777679493277,"version":"3.51.4"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,16]]},"DOI":"10.7759\/cureus.105347","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T03:47:31Z","timestamp":1773719251000},"source":"Crossref","is-referenced-by-count":1,"title":["Lacosamide-Responsive Paroxysmal Tonic Spasms Associated With a New Lateral Cerebral Peduncle Lesion in Multiple Sclerosis: A Case Report"],"prefix":"10.7759","author":[{"given":"M'hamed Riad","family":"Amanallah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza","family":"Benzakour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmina","family":"Zakaria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaoula","family":"Balili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Chraa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nissrine","family":"Louhab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrleng.2014.12.015","article-title":"Neuromyelitis optica: association with paroxysmal painful tonic spasms","volume":"31","author":"Contentti EC","year":"2016","unstructured":"Contentti EC, Leguizam\u00f3n F, Hryb JP, et al.. Neuromyelitis optica: association with paroxysmal painful tonic spasms. Neurologia. 2016, 31:511-5. 10.1016\/j.nrleng.2014.12.015","journal-title":"Neurologia"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1179\/1743132812Y.0000000082","article-title":"Multiple sclerosis and pain","volume":"34","author":"Nick ST","year":"2012","unstructured":"Nick ST, Roberts C, Billiodeaux S, et al.. Multiple sclerosis and pain. Neurol Res. 2012, 34:829-41. 10.1179\/1743132812Y.0000000082","journal-title":"Neurol Res"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0000000000000025","article-title":"Paroxysmal dystonia as a manifestation of multiple sclerosis","volume":"19","author":"Machado C","year":"2015","unstructured":"Machado C, Amorim JM, Rodrigues M, Cerqueira J, Louren\u00e7o E, Pinho J. Paroxysmal dystonia as a manifestation of multiple sclerosis. Neurologist. 2015, 19:132-4. 10.1097\/NRL.0000000000000025","journal-title":"Neurologist"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.pjnns.2014.07.009","article-title":"Symptomatology and pathogenesis of different types of pain in multiple sclerosis","volume":"48","author":"Brola W","year":"2014","unstructured":"Brola W, Mitosek-Szewczyk K, Opara J. Symptomatology and pathogenesis of different types of pain in multiple sclerosis. Neurol Neurochir Pol. 2014, 48:272-9. 10.1016\/j.pjnns.2014.07.009","journal-title":"Neurol Neurochir Pol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2013.02.007","article-title":"Movement disorders in multiple sclerosis and other demyelinating diseases","volume":"328","author":"Mehanna R","year":"2013","unstructured":"Mehanna R, Jankovic J. Movement disorders in multiple sclerosis and other demyelinating diseases. J Neurol Sci. 2013, 328:1-8. 10.1016\/j.jns.2013.02.007","journal-title":"J Neurol Sci"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9103100","article-title":"Paroxysmal symptoms in multiple sclerosis - a review of the literature","volume":"9","author":"Freiha J","year":"2020","unstructured":"Freiha J, Riachi N, Chalah MA, Zoghaib R, Ayache SS, Ahdab R. Paroxysmal symptoms in multiple sclerosis - a review of the literature. J Clin Med. 2020, 9:10.3390\/jcm9103100","journal-title":"J Clin Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-018-8989-2","article-title":"Lesion correlates of secondary paroxysmal dyskinesia in multiple sclerosis","volume":"265","author":"Fr\u00f6hlich K","year":"2018","unstructured":"Fr\u00f6hlich K, Winder K, Linker RA, et al.. Lesion correlates of secondary paroxysmal dyskinesia in multiple sclerosis. J Neurol. 2018, 265:2277-83. 10.1007\/s00415-018-8989-2","journal-title":"J Neurol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s100720100070","article-title":"Paroxysmal dystonia with thalamic lesion in multiple sclerosis","volume":"22","author":"Zenzola A","year":"2001","unstructured":"Zenzola A, De Mari M, De Blasi R, Carella A, Lamberti P. Paroxysmal dystonia with thalamic lesion in multiple sclerosis. Neurol Sci. 2001, 22:391-4. 10.1007\/s100720100070","journal-title":"Neurol Sci"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/life11080776","article-title":"Dystonia and cerebellum: from bench to bedside","volume":"11","author":"Morigaki R","year":"2021","unstructured":"Morigaki R, Miyamoto R, Matsuda T, Miyake K, Yamamoto N, Takagi Y. Dystonia and cerebellum: from bench to bedside. Life. 2021, 11:10.3390\/life11080776","journal-title":"Life"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X231167937","article-title":"Painful tonic spasms in a patient with neuromyelitis optica spectrum disorder: a case report","volume":"11","author":"Aryal R","year":"2023","unstructured":"Aryal R, Homagian S, Shrestha S, et al.. Painful tonic spasms in a patient with neuromyelitis optica spectrum disorder: a case report. SAGE Open Med Case Rep. 2023, 11:10.1177\/2050313X231167937","journal-title":"SAGE Open Med Case Rep"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2017.02.009","article-title":"Neuromyelitis optica spectrum disorder related tonic spasms responsive to lacosamide","volume":"13","author":"Baheerathan A","year":"2017","unstructured":"Baheerathan A, Brownlee WJ, Rugg-Gunn F, Chard DT, Trip SA. Neuromyelitis optica spectrum disorder related tonic spasms responsive to lacosamide. Mult Scler Relat Disord. 2017, 13:73-4. 10.1016\/j.msard.2017.02.009","journal-title":"Mult Scler Relat Disord"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.14802\/jmd.22016","article-title":"Multiple sclerosis-related paroxysmal kinesigenic dyskinesia: long term, favorable response to lacosamide","volume":"15","author":"Poulidou V","year":"2022","unstructured":"Poulidou V, Spilioti M, Moschou M, et al.. Multiple sclerosis-related paroxysmal kinesigenic dyskinesia: long term, favorable response to lacosamide. J Mov Disord. 2022, 15:286-9. 10.14802\/jmd.22016","journal-title":"J Mov Disord"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/469359-lacosamide-responsive-paroxysmal-tonic-spasms-associated-with-a-new-lateral-cerebral-peduncle-lesion-in-multiple-sclerosis-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T03:47:37Z","timestamp":1773719257000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/469359-lacosamide-responsive-paroxysmal-tonic-spasms-associated-with-a-new-lateral-cerebral-peduncle-lesion-in-multiple-sclerosis-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,16]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.105347","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,16]]}}}