{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T17:12:18Z","timestamp":1773853938820,"version":"3.50.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,18]]},"DOI":"10.7759\/cureus.105425","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:44:50Z","timestamp":1773830690000},"source":"Crossref","is-referenced-by-count":0,"title":["Antimitochondrial Antibody-Negative Primary Biliary Cholangitis: A Diagnostic Challenge in a Sri Lankan Patient"],"prefix":"10.7759","author":[{"given":"Chathura Madhushan Angulugaha","family":"Angulugaha Gamage","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhupawani Wijayasuriya","family":"Wijayasuriya Arachchige","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vajira","family":"Samarawickrama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22906","article-title":"Primary biliary cirrhosis","volume":"50","author":"Lindor KD","year":"2009","unstructured":"Lindor KD, Gershwin ME, Poupon R, Kaplan M, Bergasa NV, Heathcote EJ. Primary biliary cirrhosis. Hepatology. 2009, 50:291-308. 10.1002\/hep.22906","journal-title":"Hepatology"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra043898","article-title":"Primary biliary cirrhosis","volume":"353","author":"Kaplan MM","year":"2005","unstructured":"Kaplan MM, Gershwin ME. Primary biliary cirrhosis. N Engl J Med. 2005, 353:1261-73. 10.1056\/NEJMra043898","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.03.022","article-title":"EASL Clinical Practice Guidelines: the diagnosis and management of patients with primary biliary cholangitis","volume":"67","author":"European Association for the Study of the Liver","year":"2017","unstructured":"European Association for the Study of the Liver. EASL Clinical Practice Guidelines: the diagnosis and management of patients with primary biliary cholangitis. J Hepatol. 2017, 67:145-72. 10.1016\/j.jhep.2017.03.022","journal-title":"J Hepatol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v7.i7.926","article-title":"Primary biliary cirrhosis: pathophysiology, clinical presentation and therapy","volume":"7","author":"Purohit T","year":"2015","unstructured":"Purohit T, Cappell MS. Primary biliary cirrhosis: pathophysiology, clinical presentation and therapy. World J Hepatol. 2015, 7:926-41. 10.4254\/wjh.v7.i7.926","journal-title":"World J Hepatol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2011.03853.x","article-title":"Inflammatory disease of the bile ducts-cholangiopathies: liver biopsy challenge and clinicopathological correlation","volume":"60","author":"Portmann B","year":"2012","unstructured":"Portmann B, Zen Y. Inflammatory disease of the bile ducts-cholangiopathies: liver biopsy challenge and clinicopathological correlation. Histopathology. 2012, 60:236-48. 10.1111\/j.1365-2559.2011.03853.x","journal-title":"Histopathology"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21583","article-title":"A sensitive bead assay for antimitochondrial antibodies: chipping away at AMA-negative primary biliary cirrhosis","volume":"45","author":"Oertelt S","year":"2007","unstructured":"Oertelt S, Rieger R, Selmi C, et al.. A sensitive bead assay for antimitochondrial antibodies: chipping away at AMA-negative primary biliary cirrhosis. Hepatology. 2007, 45:659-65. 10.1002\/hep.21583","journal-title":"Hepatology"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.12.005","article-title":"Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid","volume":"148","author":"Hirschfield GM","year":"2015","unstructured":"Hirschfield GM, Mason A, Luketic V, et al.. Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid. Gastroenterology. 2015, 148:751-61. 10.1053\/j.gastro.2014.12.005","journal-title":"Gastroenterology"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2011.02.031","article-title":"Early primary biliary cirrhosis: biochemical response to treatment and prediction of long-term outcome","volume":"55","author":"Corpechot C","year":"2011","unstructured":"Corpechot C, Chazouill\u00e8res O, Poupon R. Early primary biliary cirrhosis: biochemical response to treatment and prediction of long-term outcome. J Hepatol. 2011, 55:1361-7. 10.1016\/j.jhep.2011.02.031","journal-title":"J Hepatol"},{"key":"ref9","article-title":"Antimitochondrial antibody-negative primary biliary cirrhosis","volume":"90","author":"Lacerda MA","year":"1995","unstructured":"Lacerda MA, Ludwig J, Dickson ER, Jorgensen RA, Lindor KD. Antimitochondrial antibody-negative primary biliary cirrhosis. Am J Gastroenterol. 1995, 90:247-9.","journal-title":"Am J Gastroenterol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2147\/HMER.S135337","article-title":"Biomarkers for primary biliary cholangitis: current perspectives","volume":"10","author":"Kouroumalis E","year":"2018","unstructured":"Kouroumalis E, Samonakis D, Voumvouraki A. Biomarkers for primary biliary cholangitis: current perspectives. Hepat Med. 2018, 10:43-53. 10.2147\/HMER.S135337","journal-title":"Hepat Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/473577-antimitochondrial-antibody-negative-primary-biliary-cholangitis-a-diagnostic-challenge-in-a-sri-lankan-patient","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:44:51Z","timestamp":1773830691000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/473577-antimitochondrial-antibody-negative-primary-biliary-cholangitis-a-diagnostic-challenge-in-a-sri-lankan-patient"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,18]]},"references-count":10,"URL":"https:\/\/doi.org\/10.7759\/cureus.105425","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,18]]}}}