{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T12:21:00Z","timestamp":1774009260937,"version":"3.50.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,20]]},"DOI":"10.7759\/cureus.105545","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T10:24:41Z","timestamp":1774002281000},"source":"Crossref","is-referenced-by-count":0,"title":["Postpartum Ischemic Stroke As the First Manifestation of Late-Onset Preeclampsia: A Case Report"],"prefix":"10.7759","author":[{"given":"Iliass","family":"Benaini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meriam","family":"Azirar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amine","family":"Bensaid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Zakaria","family":"Bouayed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safaa","family":"Kachmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samia","family":"Berrichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houssam","family":"Bkiyar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2109523","article-title":"Preeclampsia","volume":"386","author":"Magee LA","year":"2022","unstructured":"Magee LA, Nicolaides KH, von Dadelszen P. Preeclampsia. N Engl J Med. 2022, 386:1817-32. 10.1056\/NEJMra2109523","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurol.2021.02.001","article-title":"Cerebrovascular events during pregnancy and puerperium","volume":"177","author":"Yger M","year":"2021","unstructured":"Yger M, Weisenburger-Lile D, Alamowitch S. Cerebrovascular events during pregnancy and puerperium. Rev Neurol (Paris). 2021, 177:203-14. 10.1016\/j.neurol.2021.02.001","journal-title":"Rev Neurol (Paris)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/858134","article-title":"Preeclampsia and stroke: Risks during and after pregnancy","volume":"2011","author":"Bushnell C","year":"2011","unstructured":"Bushnell C, Chireau M. Preeclampsia and stroke: Risks during and after pregnancy. Stroke Res Treat. 2011, 2011:858134. 10.4061\/2011\/858134","journal-title":"Stroke Res Treat"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004203","article-title":"Stroke in pregnancy: A focused update","volume":"130","author":"Miller EC","year":"2020","unstructured":"Miller EC, Leffert L. Stroke in pregnancy: A focused update. Anesth Analg. 2020, 130:1085-96. 10.1213\/ANE.0000000000004203","journal-title":"Anesth Analg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-019-2339-y","article-title":"Pregnancy-associated stroke -a systematic review of subsequent pregnancies and maternal health","volume":"19","author":"Karjalainen L","year":"2019","unstructured":"Karjalainen L, Tikkanen M, Rantanen K, Laivuori H, Gissler M, Ij\u00e4s P. Pregnancy-associated stroke -a systematic review of subsequent pregnancies and maternal health. BMC Pregnancy Childbirth. 2019, 19:187. 10.1186\/s12884-019-2339-y","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.6.1274","article-title":"Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis","volume":"31","author":"Lanska DJ","year":"2000","unstructured":"Lanska DJ, Kryscio RJ. Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke. 2000, 31:1274-82. 10.1161\/01.STR.31.6.1274","journal-title":"Stroke"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.018416","article-title":"Preeclampsia: Association with posterior reversible encephalopathy syndrome and stroke","volume":"49","author":"McDermott M","year":"2018","unstructured":"McDermott M, Miller EC, Rundek T, Hurn PD, Bushnell CD. Preeclampsia: Association with posterior reversible encephalopathy syndrome and stroke. Stroke. 2018, 49:524-30. 10.1161\/STROKEAHA.117.018416","journal-title":"Stroke"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.125241","article-title":"Cerebral perfusion pressure, and not cerebral blood flow, may be the critical determinant of intracranial injury in preeclampsia: a new hypothesis","volume":"187","author":"Belfort MA","year":"2002","unstructured":"Belfort MA, Varner MW, Dizon-Townson DS, Grunewald C, Nisell H. Cerebral perfusion pressure, and not cerebral blood flow, may be the critical determinant of intracranial injury in preeclampsia: a new hypothesis. Am J Obstet Gynecol. 2002, 187:626-34. 10.1067\/mob.2002.125241","journal-title":"Am J Obstet Gynecol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-015-0575-8","article-title":"Cerebrovascular dysfunction in preeclamptic pregnancies","volume":"17","author":"Hammer ES","year":"2015","unstructured":"Hammer ES, Cipolla MJ. Cerebrovascular dysfunction in preeclamptic pregnancies. Curr Hypertens Rep. 2015, 17:64. 10.1007\/s11906-015-0575-8","journal-title":"Curr Hypertens Rep"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fmedt.2022.748949","article-title":"Detection, diagnosis and treatment of acute ischemic stroke: Current and future perspectives","volume":"4","author":"Patil S","year":"2022","unstructured":"Patil S, Rossi R, Jabrah D, Doyle K. Detection, diagnosis and treatment of acute ischemic stroke: Current and future perspectives. Front Med Technol. 2022, 4:748949. 10.3389\/fmedt.2022.748949","journal-title":"Front Med Technol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59101707","article-title":"Stroke vs. preeclampsia: Dangerous liaisons of hypertension and pregnancy","volume":"59","author":"Lackovic M","year":"2023","unstructured":"Lackovic M, Nikolic D, Jankovic M, Rovcanin M, Mihajlovic S. Stroke vs. preeclampsia: Dangerous liaisons of hypertension and pregnancy. Medicina (Kaunas). 2023, 59:1707. 10.3390\/medicina59101707","journal-title":"Medicina (Kaunas)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-229635","article-title":"Ischaemic stroke and pre-eclampsia in the third trimester of pregnancy: A diagnostic and therapeutic challenge","volume":"12","author":"Grammatis AL","year":"2019","unstructured":"Grammatis AL, Catton HL, Hilton D. Ischaemic stroke and pre-eclampsia in the third trimester of pregnancy: A diagnostic and therapeutic challenge. BMJ Case Rep. 2019, 12:e229635. 10.1136\/bcr-2019-229635","journal-title":"BMJ Case Rep"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.9975","article-title":"Postpartum ischemic stroke: A rare case","volume":"12","author":"Farooque U","year":"2020","unstructured":"Farooque U, Cheema O, Karimi S, Pillai B, Liaquat MT. Postpartum ischemic stroke: A rare case. Cureus. 2020, 12:e9975. 10.7759\/cureus.9975","journal-title":"Cureus"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/jcvs.jcvs_20_23","article-title":"Ischaemic stroke in pregnancy: Case report and review of literature","volume":"11","author":"Mnaili MA","year":"2023","unstructured":"Mnaili MA. Ischaemic stroke in pregnancy: Case report and review of literature. J Cerebrovasc Sci. 2023, 11:97-99. 10.4103\/jcvs.jcvs_20_23","journal-title":"J Cerebrovasc Sci"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci11010070","article-title":"Hypertensive crisis in acute cerebrovascular diseases presenting at the emergency department: A narrative review","volume":"11","author":"Cantone M","year":"2021","unstructured":"Cantone M, Lanza G, Puglisi V, et al.. Hypertensive crisis in acute cerebrovascular diseases presenting at the emergency department: A narrative review. Brain Sci. 2021, 11:70. 10.3390\/brainsci11010070","journal-title":"Brain Sci"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003891","article-title":"Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222","volume":"135","author":"American College of Obstetricians and Gynecologists","year":"2020","unstructured":"American College of Obstetricians and Gynecologists. Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222. Obstet Gynecol. 2020, 135:e237-60. 10.1097\/AOG.0000000000003891","journal-title":"Obstet Gynecol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.07862","article-title":"The CHIPS randomized controlled trial (control of hypertension in pregnancy study): Is severe hypertension just an elevated blood pressure?","volume":"68","author":"Magee LA","year":"2016","unstructured":"Magee LA, von Dadelszen P, Singer J, et al.. The CHIPS randomized controlled trial (control of hypertension in pregnancy study): Is severe hypertension just an elevated blood pressure?. Hypertension. 2016, 68:1153-9. 10.1161\/HYPERTENSIONAHA.116.07862","journal-title":"Hypertension"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2024.101153","article-title":"Optimal treatment for women with acute hypertension in pregnancy; a randomized trial comparing intravenous labetalol versus nicardipine","volume":"38","author":"Bij de Weg JM","year":"2024","unstructured":"Bij de Weg JM, de Boer MA, Gravesteijn BY, et al.. Optimal treatment for women with acute hypertension in pregnancy; a randomized trial comparing intravenous labetalol versus nicardipine. Pregnancy Hypertens. 2024, 38:101153. 10.1016\/j.preghy.2024.101153","journal-title":"Pregnancy Hypertens"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110196","article-title":"Methyldopa as an inductor of postpartum depression and maternal blues: A review","volume":"127","author":"Wici\u0144ski M","year":"2020","unstructured":"Wici\u0144ski M, Malinowski B, Puk O, Socha M, S\u0142upski M. Methyldopa as an inductor of postpartum depression and maternal blues: A review. Biomed Pharmacother. 2020, 127:110196. 10.1016\/j.biopha.2020.110196","journal-title":"Biomed Pharmacother"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.14744\/SEMB.2020.56650","article-title":"Adverse outcomes of preeclampsia in previous and subsequent pregnancies and the risk of recurrence","volume":"55","author":"Coban U","year":"2021","unstructured":"Coban U, Takmaz T, Unyeli OD, Ozdemir S. Adverse outcomes of preeclampsia in previous and subsequent pregnancies and the risk of recurrence. Sisli Etfal Hastan Tip Bul. 2021, 55:426-31. 10.14744\/SEMB.2020.56650","journal-title":"Sisli Etfal Hastan Tip Bul"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-28078-3","article-title":"Early initiation of low-dose aspirin for the prevention of pre-eclampsia in high-risk pregnancies","volume":"16","author":"Alsulami FT","year":"2026","unstructured":"Alsulami FT, Hamed EM. Early initiation of low-dose aspirin for the prevention of pre-eclampsia in high-risk pregnancies. Sci Rep. 2026, 16:1761. 10.1038\/s41598-025-28078-3","journal-title":"Sci Rep"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines13102337","article-title":"Low-molecular-weight heparin in preeclampsia: Effects on biomarkers and Prevention: A narrative review","volume":"13","author":"Baroutis D","year":"2025","unstructured":"Baroutis D, Koukoumpanis K, Tzanis AA, et al.. Low-molecular-weight heparin in preeclampsia: Effects on biomarkers and Prevention: A narrative review. Biomedicines. 2025, 13:2337. 10.3390\/biomedicines13102337","journal-title":"Biomedicines"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/472342-postpartum-ischemic-stroke-as-the-first-manifestation-of-late-onset-preeclampsia-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T10:24:42Z","timestamp":1774002282000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/472342-postpartum-ischemic-stroke-as-the-first-manifestation-of-late-onset-preeclampsia-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,20]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.105545","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,20]]}}}