{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T20:18:03Z","timestamp":1774037883974,"version":"3.50.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,20]]},"DOI":"10.7759\/cureus.105566","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T18:33:02Z","timestamp":1774031582000},"source":"Crossref","is-referenced-by-count":0,"title":["Acute-on-Chronic Liver Failure in a 13-Year-Old Patient With Wilson\u2019s Disease Due to Dengue Virus Infection: A Case Report"],"prefix":"10.7759","author":[{"given":"Ernesto","family":"Balmaceda Araya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari\u00e1ngeles","family":"Murillo Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Osawa Pivovarov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Robles Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Taylor Rold\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1914900","article-title":"Acute-on-chronic liver failure","volume":"382","author":"Arroyo V","year":"2020","unstructured":"Arroyo V, Moreau R, Jalan R. Acute-on-chronic liver failure. N Engl J Med. 2020, 382:2137-45. 10.1056\/NEJMra1914900","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.04.021","article-title":"EASL Clinical Practice Guidelines on acute-on-chronic liver failure","volume":"79","year":"2023","unstructured":"EASL Clinical Practice Guidelines on acute-on-chronic liver failure. J Hepatol. 2023, 79.461-91. 10.1016\/j.jhep.2023.04.021","journal-title":"J Hepatol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-019-09946-3","article-title":"Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update","volume":"13","author":"Sarin SK","year":"2019","unstructured":"Sarin SK, Choudhury A, Sharma MK, et al.. Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update. Hepatol Int. 2019, 13:353-90. 10.1007\/s12072-019-09946-3","journal-title":"Hepatol Int"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/liv.15927","article-title":"Prognosis algorithms for acute decompensation of cirrhosis and ACLF","volume":"45","author":"Valainathan SR","year":"2025","unstructured":"Valainathan SR, Xie Q, Arroyo V, Rautou PE. Prognosis algorithms for acute decompensation of cirrhosis and ACLF. Liver Int. 2025, 45:e15927. 10.1111\/liv.15927","journal-title":"Liver Int"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v13.i10.1289","article-title":"Acute-on-chronic liver failure in children","volume":"13","author":"Islek A","year":"2021","unstructured":"Islek A, Tumgor G. Acute-on-chronic liver failure in children. World J Hepatol. 2021, 13:1289-98. 10.4254\/wjh.v13.i10.1289","journal-title":"World J Hepatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-025-06987-1","article-title":"Revolutionizing Wilson disease prognosis: a machine learning approach to predict acute-on-chronic liver failure","volume":"23","author":"Rao Z","year":"2025","unstructured":"Rao Z, Yang W, Yang Y, et al.. Revolutionizing Wilson disease prognosis: a machine learning approach to predict acute-on-chronic liver failure. J Transl Med. 2025, 23:999. 10.1186\/s12967-025-06987-1","journal-title":"J Transl Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcli.2022.12.016","article-title":"Wilson's disease: overview","volume":"160","author":"Lucena-Valera A","year":"2023","unstructured":"Lucena-Valera A, Ruz-Zafra P, Ampuero J. Wilson's disease: overview. Med Clin (Barc). 2023, 160:261-7. 10.1016\/j.medcli.2022.12.016","journal-title":"Med Clin (Barc)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2019.02.006","article-title":"Wilson disease presenting with acute on chronic liver failure: a single-center experience of outcome and predictors of mortality in 68 patients","volume":"9","author":"Devarbhavi H","year":"2019","unstructured":"Devarbhavi H, Reddy VV, Singh R. Wilson disease presenting with acute on chronic liver failure: a single-center experience of outcome and predictors of mortality in 68 patients. J Clin Exp Hepatol. 2019, 9:569-73. 10.1016\/j.jceh.2019.02.006","journal-title":"J Clin Exp Hepatol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v13.i12.1968","article-title":"Dengue hemorrhagic fever and the liver","volume":"13","author":"Leowattana W","year":"2021","unstructured":"Leowattana W, Leowattana T. Dengue hemorrhagic fever and the liver. World J Hepatol. 2021, 13:1968-76. 10.4254\/wjh.v13.i12.1968","journal-title":"World J Hepatol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-7-568","article-title":"Dengue haemorrhagic fever presenting with cholestatic hepatitis: two case reports and a review of literature","volume":"7","author":"Yudhishdran J","year":"2014","unstructured":"Yudhishdran J, Navinan R, Ratnatilaka A, Jeyalakshmy S. Dengue haemorrhagic fever presenting with cholestatic hepatitis: two case reports and a review of literature. BMC Res Notes. 2014, 7:568. 10.1186\/1756-0500-7-568","journal-title":"BMC Res Notes"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.5501\/wjv.v13.i1.91457","article-title":"Dengue induced acute liver failure: a meta summary of case reports","volume":"13","author":"Juneja D","year":"2024","unstructured":"Juneja D, Jain R, Nasa P. Dengue induced acute liver failure: a meta summary of case reports. World J Virol. 2024, 13:91457. 10.5501\/wjv.v13.i1.91457","journal-title":"World J Virol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.14712\/23362936.2020.11","article-title":"Dengue infection: a hidden cause of acute insult in a case of acute on chronic liver failure in endemic area","volume":"121","author":"Paul J","year":"2020","unstructured":"Paul J. Dengue infection: a hidden cause of acute insult in a case of acute on chronic liver failure in endemic area. Prague Med Rep. 2020, 121:118-23. 10.14712\/23362936.2020.11","journal-title":"Prague Med Rep"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-012-0295-9","article-title":"Etiology, clinical profile, and inhospital mortality of acute-on-chronic liver failure: a prospective study","volume":"32","author":"Jha AK","year":"2013","unstructured":"Jha AK, Nijhawan S, Rai RR, Nepalia S, Jain P, Suchismita A. Etiology, clinical profile, and inhospital mortality of acute-on-chronic liver failure: a prospective study. Indian J Gastroenterol. 2013, 32:108-14. 10.1007\/s12664-012-0295-9","journal-title":"Indian J Gastroenterol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.11.047","article-title":"Acute-on-chronic liver failure: a distinct clinical syndrome","volume":"75 Suppl 1","author":"Moreau R","year":"2021","unstructured":"Moreau R, Gao B, Papp M, Ba\u00f1ares R, Kamath PS. Acute-on-chronic liver failure: a distinct clinical syndrome. J Hepatol. 2021, 75 Suppl 1:S27-35. 10.1016\/j.jhep.2020.11.047","journal-title":"J Hepatol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29773","article-title":"NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis","volume":"67","author":"O'Leary JG","year":"2018","unstructured":"O'Leary JG, Reddy KR, Garcia-Tsao G, et al.. NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis. Hepatology. 2018, 67:2367-74. 10.1002\/hep.29773","journal-title":"Hepatology"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.4038\/cmj.v61i1.8260","article-title":"Predicting acute liver failure in dengue infection","volume":"61","author":"Kumarasena RS","year":"2016","unstructured":"Kumarasena RS, Niriella MA, Ranawaka CK, Miththinda JK, de Silva AP, Dassanayaka AS, de Silva HJ. Predicting acute liver failure in dengue infection. Ceylon Med J. 2016, 61:35-6. 10.4038\/cmj.v61i1.8260","journal-title":"Ceylon Med J"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-023-04717-3","article-title":"Pediatric acute-on-chronic liver failure","volume":"91","author":"Alam S","year":"2024","unstructured":"Alam S, Lal BB. Pediatric acute-on-chronic liver failure. Indian J Pediatr. 2024, 91:374-82. 10.1007\/s12098-023-04717-3","journal-title":"Indian J Pediatr"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3389\/ti.2025.14752","article-title":"Liver transplantation in the context of acute-on-chronic liver failure (ACLF): where do we stand in 2025?","volume":"38","author":"L'Hermite S","year":"2025","unstructured":"L'Hermite S, Coirier V, Artru F. Liver transplantation in the context of acute-on-chronic liver failure (ACLF): where do we stand in 2025?. Transpl Int. 2025, 38:14752. 10.3389\/ti.2025.14752","journal-title":"Transpl Int"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2024.06.039","article-title":"Long-term outcome following liver transplantation of patients with ACLF grade 3","volume":"82","author":"Artru F","year":"2025","unstructured":"Artru F, Sacleux SC, Ursic-Bedoya J, et al.. Long-term outcome following liver transplantation of patients with ACLF grade 3. J Hepatol. 2025, 82:62-71. 10.1016\/j.jhep.2024.06.039","journal-title":"J Hepatol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-023-07149-x","article-title":"Intensive care management of acute-on-chronic liver failure","volume":"49","author":"Perricone G","year":"2023","unstructured":"Perricone G, Artzner T, De Martin E, Jalan R, Wendon J, Carbone M. Intensive care management of acute-on-chronic liver failure. Intensive Care Med. 2023, 49:903-21. 10.1007\/s00134-023-07149-x","journal-title":"Intensive Care Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/471231-acute-on-chronic-liver-failure-in-a-13-year-old-patient-with-wilsons-disease-due-to-dengue-virus-infection-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T18:33:02Z","timestamp":1774031582000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/471231-acute-on-chronic-liver-failure-in-a-13-year-old-patient-with-wilsons-disease-due-to-dengue-virus-infection-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,20]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.105566","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,20]]}}}