{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T19:01:05Z","timestamp":1779217265052,"version":"3.51.4"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,21]]},"DOI":"10.7759\/cureus.105589","type":"journal-article","created":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T12:18:55Z","timestamp":1774095535000},"source":"Crossref","is-referenced-by-count":1,"title":["A Rare Case of Disseminated Mycobacterium avium Complex Disease in a Patient Living With HIV Presenting With Endobronchial Lesions"],"prefix":"10.7759","author":[{"given":"Mai","family":"Motojima-Muto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuta","family":"Nanjo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riko","family":"Fujioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenta","family":"Izumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akane","family":"Hashizume","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Namba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Nagashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhisa","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofx120","article-title":"Incidence, long-term outcomes, and healthcare utilization of patients with human immunodeficiency virus\/acquired immune deficiency syndrome and disseminated Mycobacterium avium complex from 1992-2015","volume":"4","author":"Collins LF","year":"2017","unstructured":"Collins LF, Clement ME, Stout JE. Incidence, long-term outcomes, and healthcare utilization of patients with human immunodeficiency virus\/acquired immune deficiency syndrome and disseminated Mycobacterium avium complex from 1992-2015. Open Forum Infect Dis. 2017, 4:2. 10.1093\/ofid\/ofx120","journal-title":"Open Forum Infect Dis"},{"key":"ref2","unstructured":"Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV. (2024). Accessed. March 4, 2026: https:\/\/clinicalinfo.hiv.gov\/en\/guidelines\/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections\/diss...."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.11150\/kansenshogakuzasshi1970.82.341","article-title":"AIDS-related Mycobacterium avium infection dissemination in a patient with endobronchial lesions associated with immune reconstitution inflammatory syndrome","volume":"82","author":"Ogawa E","year":"2008","unstructured":"Ogawa E, Murata M, Ohnishi H, Tatsukawa M, Sawayama Y, Furusyo N, Hayashi J. AIDS-related Mycobacterium avium infection dissemination in a patient with endobronchial lesions associated with immune reconstitution inflammatory syndrome. Kansenshogaku Zasshi. 2008, 82:341-6. 10.11150\/kansenshogakuzasshi1970.82.341","journal-title":"Kansenshogaku Zasshi"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2007.22.3.215","article-title":"Mycobacterium avium complex infection presenting as an endobronchial mass in a patient with acquired immune deficiency syndrome","volume":"22","author":"Kim HC","year":"2007","unstructured":"Kim HC, Bae IG, Ma JE, Lee JS, Jeon KN, Lee JD, Hwang YS. Mycobacterium avium complex infection presenting as an endobronchial mass in a patient with acquired immune deficiency syndrome. Korean J Intern Med. 2007, 22:215-9. 10.3904\/kjim.2007.22.3.215","journal-title":"Korean J Intern Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2009.009370","article-title":"Mycobacterium avium-intracellulare presenting as an endobronchial tumour due to immune reconstitution inflammatory syndrome","volume":"23","author":"Gulati A","year":"2012","unstructured":"Gulati A, Singh S, Moussa R, Promnitz DA. Mycobacterium avium-intracellulare presenting as an endobronchial tumour due to immune reconstitution inflammatory syndrome. Int J STD AIDS. 2012, 23:441-2. 10.1258\/ijsa.2009.009370","journal-title":"Int J STD AIDS"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-015-0063-2","article-title":"Immune reconstitution inflammatory syndrome due to Mycobacterium avium complex successfully followed up using 18\u2009F-fluorodeoxyglucose positron emission tomography-computed tomography in a patient with human immunodeficiency virus infection: A case report","volume":"15","author":"Namkoong H","year":"2015","unstructured":"Namkoong H, Fujiwara H, Ishii M, et al.. Immune reconstitution inflammatory syndrome due to Mycobacterium avium complex successfully followed up using 18\u2009F-fluorodeoxyglucose positron emission tomography-computed tomography in a patient with human immunodeficiency virus infection: A case report. BMC Med Imaging. 2015, 15:24. 10.1186\/s12880-015-0063-2","journal-title":"BMC Med Imaging"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70184-1","article-title":"Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings","volume":"8","author":"Meintjes G","year":"2008","unstructured":"Meintjes G, Lawn SD, Scano F, et al.. Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings. Lancet Infect Dis. 2008, 8:516-23. 10.1016\/S1473-3099(08)70184-1","journal-title":"Lancet Infect Dis"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000131375.21070.06","article-title":"Immune restoration disease after antiretroviral therapy","volume":"18","author":"French MA","year":"2004","unstructured":"French MA, Price P, Stone SF. Immune restoration disease after antiretroviral therapy. AIDS. 2004, 18:1615-27. 10.1097\/01.aids.0000131375.21070.06","journal-title":"AIDS"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-009-0298-5","article-title":"Usefulness of F-18 FDG PET\/CT in the assessment of disseminated Mycobacterium avium complex infection","volume":"23","author":"Sato M","year":"2009","unstructured":"Sato M, Hiyama T, Kaito K, Hayashi Y, Okumura T. Usefulness of F-18 FDG PET\/CT in the assessment of disseminated Mycobacterium avium complex infection. Ann Nucl Med. 2009, 23:757-62. 10.1007\/s12149-009-0298-5","journal-title":"Ann Nucl Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10020497","article-title":"Endobronchial lesions in a non-AIDS patient with disseminated Mycobacterium avium-intracellulare infection","volume":"10","author":"Shih JY","year":"1997","unstructured":"Shih JY, Wang HC, Chiang IP, Yang PC, Luh KT. Endobronchial lesions in a non-AIDS patient with disseminated Mycobacterium avium-intracellulare infection. Eur Respir J. 1997, 10:497-9. 10.1183\/09031936.97.10020497","journal-title":"Eur Respir J"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000056323","article-title":"Disseminated Mycobacterium intracellulare infection in an HIV-negative, nonimmunosuppressed patient with multiple endobronchial polyps","volume":"69","author":"Asano T","year":"2002","unstructured":"Asano T, Itoh G, Itoh M. Disseminated Mycobacterium intracellulare infection in an HIV-negative, nonimmunosuppressed patient with multiple endobronchial polyps. Respiration. 2002, 69:175-7. 10.1159\/000056323","journal-title":"Respiration"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2169\/naika.90.1345","article-title":"Pulmonary Kaposi's sarcoma successfully diagnosed by transbronchial lung biopsy","volume":"90","author":"Ishizuka S","year":"2001","unstructured":"Ishizuka S, Kunisawa A, Minemura K, Kasuga I, Utsumi K, Miyazawa K, Ohyashiki K. Pulmonary Kaposi's sarcoma successfully diagnosed by transbronchial lung biopsy. Nihon Naika Gakkai Zasshi. 2001, 90:1345-7. 10.2169\/naika.90.1345","journal-title":"Nihon Naika Gakkai Zasshi"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2005.20.4.290","article-title":"Clinical and bronchoscopic findings in Ugandans with pulmonary Kaposi's sarcoma","volume":"20","author":"Yoo DJ","year":"2005","unstructured":"Yoo DJ, Lee KH, Munderi P, Shin KC, Lee JK. Clinical and bronchoscopic findings in Ugandans with pulmonary Kaposi's sarcoma. Korean J Intern Med. 2005, 20:290-4. 10.3904\/kjim.2005.20.4.290","journal-title":"Korean J Intern Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMicm2407099","article-title":"Endobronchial Kaposi's sarcoma","volume":"392","author":"Eika F","year":"2025","unstructured":"Eika F, Al-Saad S. Endobronchial Kaposi's sarcoma. N Engl J Med. 2025, 392:e15. 10.1056\/NEJMicm2407099","journal-title":"N Engl J Med"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309163291202","article-title":"Two controlled trials of rifabutin prophylaxis against Mycobacterium avium complex infection in AIDS","volume":"329","author":"Nightingale SD","year":"1993","unstructured":"Nightingale SD, Cameron DW, Gordin FM, et al.. Two controlled trials of rifabutin prophylaxis against Mycobacterium avium complex infection in AIDS. N Engl J Med. 1993, 329:828-33. 10.1056\/NEJM199309163291202","journal-title":"N Engl J Med"},{"key":"ref16","unstructured":"MYCOBUTIN (rifabutin) capsules. Prescribing information. (2023). Accessed. March 2, 2026: https:\/\/labeling.pfizer.com\/showlabeling.aspx?id=635."},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.66339","article-title":"Rifabutin-induced thrombocytopenia in a patient with uncontrolled HIV: a case report","volume":"16","author":"Tamr A","year":"2024","unstructured":"Tamr A, Kabbani D, Weinberger JJ. Rifabutin-induced thrombocytopenia in a patient with uncontrolled HIV: a case report. Cureus. 2024, 16:e66339. 10.7759\/cureus.66339","journal-title":"Cureus"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/875512251202800203","article-title":"Rifabutin-induced thrombocytopenia from concurrent use of high-dose fluconazole","volume":"28","author":"Frumin J","year":"2012","unstructured":"Frumin J, Yunker N. Rifabutin-induced thrombocytopenia from concurrent use of high-dose fluconazole. J Pharm Technol. 2012, 28:51-7. 10.1177\/875512251202800203","journal-title":"J Pharm Technol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/460246-a-rare-case-of-disseminated-mycobacterium-avium-complex-disease-in-a-patient-living-with-hiv-presenting-with-endobronchial-lesions","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T12:18:55Z","timestamp":1774095535000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/460246-a-rare-case-of-disseminated-mycobacterium-avium-complex-disease-in-a-patient-living-with-hiv-presenting-with-endobronchial-lesions"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,21]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.105589","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,21]]}}}