{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T15:06:56Z","timestamp":1775920016802,"version":"3.50.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,21]]},"DOI":"10.7759\/cureus.10566","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T16:52:07Z","timestamp":1600707127000},"source":"Crossref","is-referenced-by-count":6,"title":["Adductor Canal Block Duration of Analgesia Successfully Prolonged With Perineural Dexmedetomidine and Dexamethasone in Addition to IPACK Block for Total Knee Arthroplasty"],"prefix":"10.7759","author":[{"given":"Jared","family":"Herman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Urits","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Eskander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Viswanath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-009-0834-6","article-title":"Future young patient demand for primary and revision joint replacement: national projections from 2010 to 2030","author":"Kurtz SM","year":"2009","unstructured":"Kurtz SM, Lau E, Ong K, Zhao K, Kelly M, Bozic KJ. Future young patient demand for primary and revision joint replacement: national projections from 2010 to 2030. Clinical Orthopaedics and Related Research. Springer, New York, NY; 2009. 467:2606-2612. 10.1007\/s11999-009-0834-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0666-9","article-title":"Does regional anesthesia improve outcome after total knee arthroplasty?","volume":"467","author":"MacFarlane AJR","year":"2009","unstructured":"MacFarlane AJR, Arun Prasad G, Chan VWS, Brull R. Does regional anesthesia improve outcome after total knee arthroplasty?. Clin Orthop Relat Res. 2009, 467:2379-2402. 10.1007\/s11999-008-0666-9","journal-title":"Clin Orthop Relat Res"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.trap.2015.10.011","article-title":"The adductor canal catheter and interspace between the popliteal artery and the posterior capsule of the knee for total knee arthroplasty","volume":"18","author":"Elliott CE","year":"2014","unstructured":"Elliott CE, Thobhani S. The adductor canal catheter and interspace between the popliteal artery and the posterior capsule of the knee for total knee arthroplasty. Tech Reg Anesth Pain Manag. 2014, 18:126-129. 10.1053\/j.trap.2015.10.011","journal-title":"Tech Reg Anesth Pain Manag"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2019.08.021","article-title":"Ambulatory knee replacements with IPACK block","volume":"60","author":"Jinadu S","year":"2020","unstructured":"Jinadu S, Pai P, Lai Y. Ambulatory knee replacements with IPACK block. J Clin Anesth. 2020, 60:55-56. 10.1016\/j.jclinane.2019.08.021","journal-title":"J Clin Anesth"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-018-2218-7","article-title":"Comparison of adductor canal block and IPACK block (interspace between the popliteal artery and the capsule of the posterior knee) with adductor canal block alone after total knee arthroplasty: a prospective control trial on pain and knee function in immediate postoperative period","volume":"28","author":"Sankineani SR","year":"2018","unstructured":"Sankineani SR, Reddy ARC, Eachempati KK, Jangale A, Gurava Reddy A V. Comparison of adductor canal block and IPACK block (interspace between the popliteal artery and the capsule of the posterior knee) with adductor canal block alone after total knee arthroplasty: a prospective control trial on pain and knee function in immediate postoperative period. Eur J Orthop Surg Traumatol. 2018, 28:1391-1395. 10.1007\/s00590-018-2218-7","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1700840","article-title":"Decreased opioid consumption and length of stay using an IPACK and adductor canal nerve block following total knee arthroplasty [Online ahead of print]","author":"Eccles CJ","year":"2019","unstructured":"Eccles CJ, Swiergosz AM, Smith AF, Bhimani SJ, Smith LS, Malkani AL. Decreased opioid consumption and length of stay using an IPACK and adductor canal nerve block following total knee arthroplasty [Online ahead of print]. J Knee Surg. 2019, 10.1055\/s-0039-1700840","journal-title":"J Knee Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4103\/ija.IJA_277_17","article-title":"Adductor canal block for post-operative analgesia after simultaneous bilateral total knee replacement: a randomised controlled trial to study the effect of addition of dexmedetomidine to ropivacaine","volume":"61","author":"Goyal R","year":"2017","unstructured":"Goyal R, Mittal G, Yadav AK, Sethi R, Chattopadhyay A. Adductor canal block for post-operative analgesia after simultaneous bilateral total knee replacement: a randomised controlled trial to study the effect of addition of dexmedetomidine to ropivacaine. Indian J Anaesth. 2017, 61:903-909. 10.4103\/ija.IJA_277_17","journal-title":"Indian J Anaesth"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000100680.77978.66","article-title":"Adding dexmedetomidine to lidocaine for intravenous regional anesthesia","volume":"98","author":"Memi\u015f D","year":"2004","unstructured":"Memi\u015f D, Turan A, Karamanlio\u011flu B, Pamuk\u00e7u Z, Kurt I. Adding dexmedetomidine to lidocaine for intravenous regional anesthesia. Anesth Analg. 2004, 98:835-840. 10.1213\/01.ane.0000100680.77978.66","journal-title":"Anesth Analg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200408000-00031","article-title":"Clonidine prolongation of lidocaine analgesia after sciatic nerve block in rats is mediated via the hyperpolarization-activated cation current, not by \u03b1-adrenoreceptors","volume":"101","author":"Kroin JS","year":"2004","unstructured":"Kroin JS, Buvanendran A, Beck DR, Topic JE, Watts DE, Tuman KJ. Clonidine prolongation of lidocaine analgesia after sciatic nerve block in rats is mediated via the hyperpolarization-activated cation current, not by \u03b1-adrenoreceptors. Anesthesiology. 2004, 101:488-494. 10.1097\/00000542-200408000-00031","journal-title":"Anesthesiology"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1042\/cs0940557","article-title":"Anti-inflammatory actions of glucocorticoids: molecular mechanisms","volume":"94","author":"Barnes PJ","year":"1998","unstructured":"Barnes PJ. Anti-inflammatory actions of glucocorticoids: molecular mechanisms. J Biogeogr. 1998, 94:557-572. 10.1042\/cs0940557","journal-title":"J Biogeogr"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1292","article-title":"Ultrasound-guided adductor canal block after arthroscopic anterior cruciate ligament reconstruction: effect of adding dexamethasone to bupivacaine, a randomized controlled trial","volume":"23","author":"Ibrahim AS","year":"2019","unstructured":"Ibrahim AS, Aly MG, Farrag WS, Gad EL-Rab NA, Said HG, Saad AH. Ultrasound-guided adductor canal block after arthroscopic anterior cruciate ligament reconstruction: effect of adding dexamethasone to bupivacaine, a randomized controlled trial. Eur J Pain (United Kingdom). 2019, 23:135-141. 10.1002\/ejp.1292","journal-title":"Eur J Pain (United Kingdom)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4103\/aer.aer_77_18","article-title":"Caudal analgesia for hypospadias in pediatrics: Comparative evaluation of adjuvants dexamethasone and dexmedetomidine combination versus dexamethasone or dexmedetomidine to bupivacaine: a prospective, double-blinded, randomized comparative study","volume":"12","author":"Hassan P","year":"2018","unstructured":"Hassan P, Hassan A, Elmetwally S. Caudal analgesia for hypospadias in pediatrics: Comparative evaluation of adjuvants dexamethasone and dexmedetomidine combination versus dexamethasone or dexmedetomidine to bupivacaine: a prospective, double-blinded, randomized comparative study. Anesth Essays Res. 2018, 12: 644-650. 10.4103\/aer.aer_77_18","journal-title":"Anesth Essays Res"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/38111-adductor-canal-block-duration-of-analgesia-successfully-prolonged-with-perineural-dexmedetomidine-and-dexamethasone-in-addition-to-ipack-block-for-total-knee-arthroplasty","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:26:48Z","timestamp":1707506808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/38111-adductor-canal-block-duration-of-analgesia-successfully-prolonged-with-perineural-dexmedetomidine-and-dexamethasone-in-addition-to-ipack-block-for-total-knee-arthroplasty"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,21]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.10566","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9,21]]}}}