{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:58:14Z","timestamp":1791496694368,"version":"4.3.4"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,22]]},"DOI":"10.7759\/cureus.10603","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T06:38:05Z","timestamp":1600843085000},"source":"Crossref","is-referenced-by-count":12,"title":["Is Hyperthyroidism a Possible Etiology of Early Onset Dementia?"],"prefix":"10.7759","author":[{"given":"Christopher","family":"Joy Mathew","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merin Tresa","family":"Jose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abeer O","family":"Elshaikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Cancarevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00278-6","article-title":"Hyperthyroidism","volume":"388","author":"De Leo S","year":"2016","unstructured":"De Leo S, Lee SY, Braverman LE. Hyperthyroidism. Lancet. 2016, 388:906-918. 10.1016\/S0140-6736(16)00278-6","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4158\/EP12280.GL","article-title":"Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association","volume":"18","author":"Garber JR","year":"2012","unstructured":"Garber JR, Cobin RH, Gharib H, et al.. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr Pract. 2012, 18:988-1028. 10.4158\/EP12280.GL","journal-title":"Endocr Pract"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1323807","article-title":"Mental health status and factors that influence the course of Graves' disease and antithyroid treatments","volume":"120","author":"Chen DY","year":"2012","unstructured":"Chen DY, Schneider PF, Zhang XS, He ZM. Mental health status and factors that influence the course of Graves' disease and antithyroid treatments. Exp Clin Endocrinol Diabetes. 2012, 120:524-528. 10.1055\/s-0032-1323807","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2016.03.001","article-title":"2016 Alzheimer's disease facts and figures","volume":"12","author":"Alzheimer's Association","year":"2016","unstructured":"Alzheimer's Association. 2016 Alzheimer's disease facts and figures. Alzheimers Dement. 2016, 12:459-509. 10.1016\/j.jalz.2016.03.001","journal-title":"Alzheimers Dement"},{"key":"ref5","unstructured":"Dementia. (2019). Accessed. July 19, 2020: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dementia."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-804766-8.00024-8","article-title":"Chapter 24 - Neuropsychiatric symptoms in dementia","volume":"167","author":"Radue R","year":"2019","unstructured":"Radue R, Walaszek A, Asthana S. Chapter 24 - Neuropsychiatric symptoms in dementia. Handb Clin Neurol. 2019, 167:437-454. 10.1016\/B978-0-12-804766-8.00024-8","journal-title":"Handb Clin Neurol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2018.06.009","article-title":"Behavioral problems and dementia","volume":"34","author":"Volicer L","year":"2018","unstructured":"Volicer L. Behavioral problems and dementia. Clin Geriatr Med. 2018, 34:637-651. 10.1016\/j.cger.2018.06.009","journal-title":"Clin Geriatr Med"},{"key":"ref8","doi-asserted-by":"crossref","DOI":"10.1016\/S0749-0690(18)30290-8","article-title":"Hyperthyroidism in the elderly","volume":"11","author":"Gambert SR","year":"1995","unstructured":"Gambert SR. Hyperthyroidism in the elderly. Clin Geriatr Med. 1995, 11:181-188.","journal-title":"Clin Geriatr Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2105\/ajph.88.9.1337","article-title":"Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset","volume":"88","author":"Brookmeyer R","year":"1998","unstructured":"Brookmeyer R, Gray S, Kawas C. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health. 1998, 88:1337-1342. 10.2105\/ajph.88.9.1337","journal-title":"Am J Public Health"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj1954.35.585","article-title":"Effects of low dose L-triiodothyronine administration on mental, behavioral, and thyroid states in elderly subjects","volume":"35","author":"Mori T","year":"1988","unstructured":"Mori T, Inoue D, Kosugi S, et al.. Effects of low dose L-triiodothyronine administration on mental, behavioral, and thyroid states in elderly subjects. Endocrinol Jpn. 1988, 35:585-592. 10.1507\/endocrj1954.35.585","journal-title":"Endocrinol Jpn"},{"key":"ref11","article-title":"Vliv normalizace izolovan\u0115 zv\u00fdsen\u00e9ho TSH na neuropsychologick\u00fd profil pacient\u016f [Effect of normalization of an isolated increase in TSH on the neuropsychological profile of patients]","volume":"139","author":"Jensovsk\u00fd J","year":"2000","unstructured":"Jensovsk\u00fd J, Spackov\u00e1 N, Hejdukov\u00e1 B, R\u016fzicka E. Vliv normalizace izolovan\u0115 zv\u00fdsen\u00e9ho TSH na neuropsychologick\u00fd profil pacient\u016f [Effect of normalization of an isolated increase in TSH on the neuropsychological profile of patients]. Cas Lek Cesk. 2000, 139:313-316.","journal-title":"Cas Lek Cesk"},{"key":"ref12","article-title":"Preliminary study of the relationship between thyroid status and cognitive and neuropsychiatric functioning in euthyroid patients with Alzheimer dementia","volume":"17","author":"Stern RA","year":"2004","unstructured":"Stern RA, Davis JD, Rogers BL, et al.. Preliminary study of the relationship between thyroid status and cognitive and neuropsychiatric functioning in euthyroid patients with Alzheimer dementia. Cogn Behav Neurol. 2004, 17:219-223.","journal-title":"Cogn Behav Neurol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-2108","article-title":"Higher free thyroxine levels predict increased incidence of dementia in older men: the Health in Men Study","volume":"97","author":"Yeap BB","year":"2012","unstructured":"Yeap BB, Alfonso H, Chubb SA, et al.. Higher free thyroxine levels predict increased incidence of dementia in older men: the Health in Men Study. J Clin Endocrinol Metab. 2012, 97:2230-2237. 10.1210\/jc.2012-2108","journal-title":"J Clin Endocrinol Metab"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ15-0458","article-title":"Does low-normal serum TSH level adversely impact cognition in elderly adults and might methimazole therapy improve outcomes?","volume":"63","author":"Chachamovitz DS","year":"2016","unstructured":"Chachamovitz DS, Vig\u00e1rio Pdos S, Silva SO, et al.. Does low-normal serum TSH level adversely impact cognition in elderly adults and might methimazole therapy improve outcomes?. Endocr J. 2016, 63:495-505. 10.1507\/endocrj.EJ15-0458","journal-title":"Endocr J"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2016-2129","article-title":"Subclinical thyroid dysfunction and the risk of cognitive decline: a meta-analysis of prospective cohort studies","volume":"101","author":"Rieben C","year":"2016","unstructured":"Rieben C, Segna D, da Costa BR, et al.. Subclinical thyroid dysfunction and the risk of cognitive decline: a meta-analysis of prospective cohort studies. J Clin Endocrinol Metab. 2016, 101:4945-4954. 10.1210\/jc.2016-2129","journal-title":"J Clin Endocrinol Metab"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1677\/joe.1.06131","article-title":"Thyroid hormone in health and disease","volume":"187","author":"Boelaert K","year":"2005","unstructured":"Boelaert K, Franklyn JA. Thyroid hormone in health and disease. J Endocrinol. 2005, 187:1-15. 10.1677\/joe.1.06131","journal-title":"J Endocrinol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.14740\/jem588","article-title":"Association between thyroid dysfunction and incident dementia in the atherosclerosis risk in communities neurocognitive study","volume":"9","author":"George KM","year":"2019","unstructured":"George KM, Lutsey PL, Selvin E, et al.. Association between thyroid dysfunction and incident dementia in the atherosclerosis risk in communities neurocognitive study. J Endocrinol Metab. 2019, 9:82-89. 10.14740\/jem588","journal-title":"J Endocrinol Metab"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1996.d01-1558.x","article-title":"The prevalence of affective disorder and in particular of a rapid cycling of bipolar disorder in patients with abnormal thyroid function tests","volume":"45","author":"Oomen HA","year":"1996","unstructured":"Oomen HA, Schipperijn AJ, Drexhage HA. The prevalence of affective disorder and in particular of a rapid cycling of bipolar disorder in patients with abnormal thyroid function tests. Clin Endocrinol (Oxf). 1996, 45:215-223. 10.1046\/j.1365-2265.1996.d01-1558.x","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2000.01146.x","article-title":"Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study","volume":"53","author":"Kalmijn S","year":"2000","unstructured":"Kalmijn S, Mehta KM, Pols HA, et al.. Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study. Clin Endocrinol (Oxf). 2000, 53:733-737. 10.1046\/j.1365-2265.2000.01146.x","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref20","article-title":"Subclinical hyperthyroidism in dementia and correlation of the metabolic index in FDG-PET","volume":"30","author":"D\u00f6bert N","year":"2003","unstructured":"D\u00f6bert N, Hamscho N, Menzel C, et al.. Subclinical hyperthyroidism in dementia and correlation of the metabolic index in FDG-PET. Acta Med Austriaca. 2003, 30:130-133.","journal-title":"Acta Med Austriaca"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-10-298","article-title":"Subclinical hyperthyroidism and dementia: the Sao Paulo Ageing & Health Study (SPAH)","volume":"10","author":"Bense\u00f1or IM","year":"2010","unstructured":"Bense\u00f1or IM, Lotufo PA, Menezes PR, Scazufca M. Subclinical hyperthyroidism and dementia: the Sao Paulo Ageing &amp; Health Study (SPAH). BMC Public Health. 2010, 10:298. 10.1186\/1471-2458-10-298","journal-title":"BMC Public Health"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-2284","article-title":"The thyroid in mind: cognitive function and low thyrotropin in older people","volume":"97","author":"Gan EH","year":"2012","unstructured":"Gan EH, Pearce SH. The thyroid in mind: cognitive function and low thyrotropin in older people. J Clin Endocrinol Metab. 2012, 97:3438-3449. 10.1210\/jc.2012-2284","journal-title":"J Clin Endocrinol Metab"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-3385","article-title":"Lower-but-normal serum TSH level is associated with the development or progression of cognitive impairment in elderly: Korean Longitudinal Study on Health and Aging (KLoSHA)","volume":"99","author":"Moon JH","year":"2014","unstructured":"Moon JH, Park YJ, Kim TH, et al.. Lower-but-normal serum TSH level is associated with the development or progression of cognitive impairment in elderly: Korean Longitudinal Study on Health and Aging (KLoSHA). J Clin Endocrinol Metab. 2014, 99:424-432. 10.1210\/jc.2013-3385","journal-title":"J Clin Endocrinol Metab"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.4103\/0972-2327.116916","article-title":"A cross-sectional study on thyroid status in North Indian elderly outpatients with dementia","volume":"16","author":"Agarwal R","year":"2013","unstructured":"Agarwal R, Kushwaha S, Chhillar N, et al.. A cross-sectional study on thyroid status in North Indian elderly outpatients with dementia. Ann Indian Acad Neurol. 2013, 16:333-337. 10.4103\/0972-2327.116916","journal-title":"Ann Indian Acad Neurol"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1038\/srep31975","article-title":"Higher FT4 or TSH below the normal range are associated with increased risk of dementia: a meta-analysis of 11 studies","volume":"6","author":"Wu Y","year":"2016","unstructured":"Wu Y, Pei Y, Wang F, Xu D, Cui W. Higher FT4 or TSH below the normal range are associated with increased risk of dementia: a meta-analysis of 11 studies. Sci Rep. 2016, 6:31975. 10.1038\/srep31975","journal-title":"Sci Rep"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.46.30366","article-title":"Thyroid hormone negatively regulates the transcriptional activity of the beta-amyloid precursor protein gene","volume":"273","author":"Belandia B","year":"1998","unstructured":"Belandia B, Latasa MJ, Villa A, Pascual A. Thyroid hormone negatively regulates the transcriptional activity of the beta-amyloid precursor protein gene. J Biol Chem. 1998, 273:30366-30371. 10.1074\/jbc.273.46.30366","journal-title":"J Biol Chem"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1210\/endo.139.6.6033","article-title":"Thyroid hormones regulate beta-amyloid gene splicing and protein secretion in neuroblastoma cell","volume":"139","author":"Latasa MJ","year":"1998","unstructured":"Latasa MJ, Belandia B, Pascual A. Thyroid hormones regulate beta-amyloid gene splicing and protein secretion in neuroblastoma cell. Endocrinology. 1998, 139:2692-2698.  10.1210\/endo.139.6.6033","journal-title":"Endocrinology"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2006.16.1207","article-title":"Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models","volume":"16","author":"O\u2019Barr SA","year":"2006","unstructured":"O\u2019Barr SA, Oh JS, Ma C, Brent GA, Schultz JJ. Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models. Thyroid. 2006, 16:1207-1213.  10.1089\/thy.2006.16.1207","journal-title":"Thyroid"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000172914.08967.dc","article-title":"Aggregation of vascular risk factors and risk of incident Alzheimer\u2019s disease","volume":"65","author":"Luchsinger JA","year":"2005","unstructured":"Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R. Aggregation of vascular risk factors and risk of incident Alzheimer\u2019s disease. Neurology. 2005, 65:545-551. 10.1212\/01.wnl.0000172914.08967.dc","journal-title":"Neurology"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53360.x","article-title":"Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort","volume":"53","author":"Newman AB","year":"2005","unstructured":"Newman AB, Fitzpatrick AL, Lopez O, et al.. Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort. J Am Geriatr Soc. 2005, 53:1101-1107. 10.1111\/j.1532-5415.2005.53360.x","journal-title":"J Am Geriatr Soc"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.21.2467","article-title":"Subclinical thyroid dysfunction as a risk factor for cardiovascular disease","volume":"165","author":"Walsh JP","year":"2005","unstructured":"Walsh JP, Bremner AP, Bulsara MK, et al.. Subclinical thyroid dysfunction as a risk factor for cardiovascular disease. Arch Intern Med. 2005, 165:2467-2472. 10.1001\/archinte.165.21.2467","journal-title":"Arch Intern Med"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-132-4-200002150-00004","article-title":"Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam study","volume":"132","author":"Hak AE","year":"2000","unstructured":"Hak AE, Pols HAP, Visser TJ, Drexhage HA, Hofman A, Witteman JC. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam study. Ann Intern Med. 2000, 132:270-278. 10.7326\/0003-4819-132-4-200002150-00004","journal-title":"Ann Intern Med"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1136\/heart.84.4.455","article-title":"Thyroid disease and the heart","volume":"84","author":"Toft AD","year":"2000","unstructured":"Toft AD, Boon NA. Thyroid disease and the heart. Heart. 2000, 84:455-460. 10.1136\/heart.84.4.455","journal-title":"Heart"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1331","article-title":"The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe","volume":"92","author":"de Jong FJ","year":"2007","unstructured":"de Jong FJ, Peeters RP, den Heijer T, et al.. The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe. J Clin Endocrinol Metab. 2007, 92:636-640. 10.1210\/jc.2006-1331","journal-title":"J Clin Endocrinol Metab"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-978808","article-title":"Oxidative stress and anti-oxidant metabolites in patients with hyperthyroidism: effect of treatment","volume":"31","author":"Bianchi G","year":"1999","unstructured":"Bianchi G, Solaroli E, Zaccheroni V, et al.. Oxidative stress and anti-oxidant metabolites in patients with hyperthyroidism: effect of treatment. Horm Metab Res. 1999, 31:620-624. 10.1055\/s-2007-978808","journal-title":"Horm Metab Res"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2008.05.008","article-title":"Thyroid function and cognitive decline in the MRC Cognitive Function and Ageing Study","volume":"33","author":"Hogervorst E","year":"2008","unstructured":"Hogervorst E, Huppert F, Matthews FE, Brayne C. Thyroid function and cognitive decline in the MRC Cognitive Function and Ageing Study. Psychoneuroendocrinology. 2008, 33:1013-1022. 10.1016\/j.psyneuen.2008.05.008","journal-title":"Psychoneuroendocrinology"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2009-0991","article-title":"Thyroid function and Alzheimer's disease","volume":"16","author":"Tan ZS","year":"2009","unstructured":"Tan ZS, Vasan RS. Thyroid function and Alzheimer's disease. J Alzheimers Dis. 2009, 16:503-507. 10.3233\/JAD-2009-0991","journal-title":"J Alzheimers Dis"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2013.08.010","article-title":"Neuroserpin up-regulation in the Alzheimer's disease brain is associated with elevated thyroid hormone receptor-\u03b21 and HuD expression","volume":"63","author":"Subhadra B","year":"2013","unstructured":"Subhadra B, Schaller K, Seeds NW. Neuroserpin up-regulation in the Alzheimer's disease brain is associated with elevated thyroid hormone receptor-\u03b21 and HuD expression. Neurochem Int. 2013, 63:476-481. 10.1016\/j.neuint.2013.08.010","journal-title":"Neurochem Int"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.31531\/2581-4745.1000104","article-title":"Thyroid hormone enhances neurite outgrowth in neuroscreen 1 cells","volume":"1","author":"Oldham CE","year":"2018","unstructured":"Oldham CE, Wooten CJ, Williams AB, Dixon S, Lopez D. Thyroid hormone enhances neurite outgrowth in neuroscreen 1 cells. Int J Biomed Investig. 2018, 1:104. 10.31531\/2581-4745.1000104","journal-title":"Int J Biomed Investig"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2020.135003","article-title":"Serum tau levels are increased in patients with hyperthyroidism","volume":"729","author":"Li LX","year":"2020","unstructured":"Li LX, Yang T, Guo L, et al.. Serum tau levels are increased in patients with hyperthyroidism. Neurosci Lett. 2020, 729:135003. 10.1016\/j.neulet.2020.135003","journal-title":"Neurosci Lett"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.1979.11715283","article-title":"Thyrotoxicosis as a mimic of dementia and\/or stroke-like syndrome","volume":"66","author":"Portnoi VA","year":"1979","unstructured":"Portnoi VA. Thyrotoxicosis as a mimic of dementia and\/or stroke-like syndrome. Postgrad Med. 1979, 66:219-221. 10.1080\/00325481.1979.11715283","journal-title":"Postgrad Med"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1990.tb03063.x","article-title":"An investigation of dementia among elderly outpatients","volume":"82","author":"Cunha UG","year":"1990","unstructured":"Cunha UG. An investigation of dementia among elderly outpatients. Acta Psychiatr Scand. 1990, 82:261-263. 10.1111\/j.1600-0447.1990.tb03063.x","journal-title":"Acta Psychiatr Scand"},{"key":"ref43","doi-asserted-by":"crossref","DOI":"10.5694\/j.1326-5377.1996.tb94135.x","article-title":"Hyperthyroidism in elderly hospitalised patients: clinical features and treatment outcomes","volume":"164","author":"Martin FI","year":"1996","unstructured":"Martin FI, Deam DR. Hyperthyroidism in elderly hospitalised patients: clinical features and treatment outcomes. Med J Aust. 1996, 164:200-203.","journal-title":"Med J Aust"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-510x(00)00487-1","article-title":"Hyperthyroid dementia: clinicoradiological findings and response to treatment","volume":"184","author":"Fukui T","year":"2001","unstructured":"Fukui T, Hasegawa Y, Takenaka H. Hyperthyroid dementia: clinicoradiological findings and response to treatment. J Neurol Sci. 2001, 184:81-88. 10.1016\/s0022-510x(00)00487-1","journal-title":"J Neurol Sci"},{"key":"ref45","article-title":"Transient dementia during hyperthyroidism of painless thyroiditis: a case report","volume":"43","author":"Ii Y","year":"2003","unstructured":"Ii Y, Ohira T, Narita Y, Kuzuhara S. Transient dementia during hyperthyroidism of painless thyroiditis: a case report. Rinsho Shinkeigaku. 2003, 43:341-344.","journal-title":"Rinsho Shinkeigaku"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.2298\/sarh05s1088z","article-title":"Autoimmune thyroid disease and brain","volume":"133","author":"Zarkovi\u0107 M","year":"2005","unstructured":"Zarkovi\u0107 M. Autoimmune thyroid disease and brain. Srp Arh Celok Lek. 2005, 133:88-91. 10.2298\/sarh05s1088z","journal-title":"Srp Arh Celok Lek"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.3390\/nu11122900","article-title":"Vitamin E supplementation and mitochondria in experimental and functional hyperthyroidism: a mini-review","volume":"11","author":"Napolitano G","year":"2019","unstructured":"Napolitano G, Fasciolo G, Di Meo S, Venditti P. Vitamin E supplementation and mitochondria in experimental and functional hyperthyroidism: a mini-review. Nutrients. 2019, 11:2900. 10.3390\/nu11122900","journal-title":"Nutrients"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ando.2020.03.003","article-title":"\"Is there any reason to treat subclinical hypo and hyperthyroidism?\"","volume":"S0003-4266","author":"Biondi B","year":"2020","unstructured":"Biondi B. \"Is there any reason to treat subclinical hypo and hyperthyroidism?\". Ann Endocrinol (Paris). 2020, S0003-4266:30038-X. 10.1016\/j.ando.2020.03.003","journal-title":"Ann Endocrinol (Paris)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/40950-is-hyperthyroidism-a-possible-etiology-of-early-onset-dementia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:26:32Z","timestamp":1707506792000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/40950-is-hyperthyroidism-a-possible-etiology-of-early-onset-dementia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,22]]},"references-count":48,"URL":"https:\/\/doi.org\/10.7759\/cureus.10603","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9,22]]}}}