{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:47:59Z","timestamp":1774745279658,"version":"3.50.1"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,28]]},"DOI":"10.7759\/cureus.106041","type":"journal-article","created":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:16:50Z","timestamp":1774743410000},"source":"Crossref","is-referenced-by-count":0,"title":["Acute Megakaryoblastic Leukemia With Myeloid Sarcoma in the Temporal Bone: A Case Report"],"prefix":"10.7759","author":[{"given":"Nozomi","family":"Fujisawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takefumi","family":"Kamakura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maki","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Yamasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Mishiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-103-3-460","article-title":"Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). A report of the French-American-British Cooperative Group","volume":"103","author":"Bennett JM","year":"1985","unstructured":"Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, Sultan C. Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). A report of the French-American-British Cooperative Group. Ann Intern Med. 1985, 103:460-2. 10.7326\/0003-4819-103-3-460","journal-title":"Ann Intern Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.v97.12.3727","article-title":"Biology and outcome of childhood acute megakaryoblastic leukemia: a single institution's experience","volume":"97","author":"Athale UH","year":"2001","unstructured":"Athale UH, Razzouk BI, Raimondi SC, et al.. Biology and outcome of childhood acute megakaryoblastic leukemia: a single institution's experience. Blood. 2001, 97:3727-32. 10.1182\/blood.v97.12.3727","journal-title":"Blood"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2450","article-title":"Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center","volume":"107","author":"Oki Y","year":"2006","unstructured":"Oki Y, Kantarjian HM, Zhou X, et al.. Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center. Blood. 2006, 107:880-4. 10.1182\/blood-2005-06-2450","journal-title":"Blood"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3772","article-title":"Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes","volume":"49","author":"de Rooij JD","year":"2017","unstructured":"de Rooij JD, Branstetter C, Ma J, et al.. Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes. Nat Genet. 2017, 49:451-6. 10.1038\/ng.3772","journal-title":"Nat Genet"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2350\/11-12-1124-CR.1","article-title":"Clinicopathological characteristics of extramedullary acute megakaryoblastic leukemia (AMKL): report of a case with initial mastoid presentation and review of literature to compare extramedullary AMKL and non-AMKL cases","volume":"15","author":"Liang C","year":"2012","unstructured":"Liang C, Chan KH, Yoon PJ, Lovell MA. Clinicopathological characteristics of extramedullary acute megakaryoblastic leukemia (AMKL): report of a case with initial mastoid presentation and review of literature to compare extramedullary AMKL and non-AMKL cases. Pediatr Dev Pathol. 2012, 15:385-92. 10.2350\/11-12-1124-CR.1","journal-title":"Pediatr Dev Pathol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.79.1.0128","article-title":"Megakaryoblastic leukemia presenting as a temporal bone granulocytic sarcoma. Case report","volume":"79","author":"Kaufman BA","year":"1993","unstructured":"Kaufman BA, Jones L, Zutter MM, Park TS. Megakaryoblastic leukemia presenting as a temporal bone granulocytic sarcoma. Case report. J Neurosurg. 1993, 79:128-31. 10.3171\/jns.1993.79.1.0128","journal-title":"J Neurosurg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.922662","article-title":"Clinical characteristics and prognosis of 27 patients with childhood acute megakaryoblastic leukemia","volume":"26","author":"Qi H","year":"2020","unstructured":"Qi H, Mao Y, Cao Q, et al.. Clinical characteristics and prognosis of 27 patients with childhood acute megakaryoblastic leukemia. Med Sci Monit. 2020, 26:e922662. 10.12659\/MSM.922662","journal-title":"Med Sci Monit"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2023.2231731","article-title":"Analysis 33 patients of non-DS-AMKL with or without acquired trisomy 21 from multiple centers and compared to 118 AML patients","volume":"28","author":"Zhang W","year":"2023","unstructured":"Zhang W, Dun J, Li H, et al.. Analysis 33 patients of non-DS-AMKL with or without acquired trisomy 21 from multiple centers and compared to 118 AML patients. Hematology. 2023, 28:2231731. 10.1080\/16078454.2023.2231731","journal-title":"Hematology"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-024-03766-z","article-title":"Myeloid sarcoma with RBM15::MRTFA (MKL1) mimicking vascular neoplasm","volume":"486","author":"G\u00fcndo\u011fdu F","year":"2025","unstructured":"G\u00fcndo\u011fdu F, Agaimy A, Ayta\u00e7 S, Hazar V, \u00dcner A, K\u00f6semehmeto\u011flu K. Myeloid sarcoma with RBM15::MRTFA (MKL1) mimicking vascular neoplasm. Virchows Arch. 2025, 486:405-10. 10.1007\/s00428-024-03766-z","journal-title":"Virchows Arch"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.12659\/ajcr.901855","article-title":"A novel variant t(1;22) translocation - ins(22;1)(q13;p13p31) - in a child with acute megakaryoblastic leukemia","volume":"18","author":"Margolskee E","year":"2017","unstructured":"Margolskee E, Saab J, Geyer JT, Aledo A, Mathew S. A novel variant t(1;22) translocation - ins(22;1)(q13;p13p31) - in a child with acute megakaryoblastic leukemia. Am J Case Rep. 2017, 18:422-6. 10.12659\/ajcr.901855","journal-title":"Am J Case Rep"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.246.141","article-title":"Myeloid sarcoma of the paranasal sinuses in a patient with acute myeloid leukemia","volume":"246","author":"Suzuki J","year":"2018","unstructured":"Suzuki J, Harazaki Y, Morita S, Kaga Y, Nomura K, Sugawara M, Katori Y. Myeloid sarcoma of the paranasal sinuses in a patient with acute myeloid leukemia. Tohoku J Exp Med. 2018, 246:141-6. 10.1620\/tjem.246.141","journal-title":"Tohoku J Exp Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/461862-acute-megakaryoblastic-leukemia-with-myeloid-sarcoma-in-the-temporal-bone-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:16:51Z","timestamp":1774743411000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/461862-acute-megakaryoblastic-leukemia-with-myeloid-sarcoma-in-the-temporal-bone-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,28]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.106041","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,28]]}}}