{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T08:10:38Z","timestamp":1775117438648,"version":"3.50.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,2]]},"DOI":"10.7759\/cureus.106308","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T07:35:03Z","timestamp":1775115303000},"source":"Crossref","is-referenced-by-count":0,"title":["Knowledge, Attitudes, and Prescribing Practices of Primary Healthcare Physicians Regarding Proton Pump Inhibitor Use in the United Arab Emirates: A Cross-Sectional Study"],"prefix":"10.7759","author":[{"given":"Zainab M","family":"Alameeri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alya R","family":"Alshemeili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar A","family":"Alhajri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem M","family":"Alketbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra M","family":"Sajwani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2021.04.033","article-title":"Use of proton pump inhibitors: an exploration of awareness, attitude and behavior of health care professionals of Riyadh, Saudi Arabia","volume":"29","author":"Asdaq SM","year":"2021","unstructured":"Asdaq SM, ALbasha M, Almutairi A, et al.. Use of proton pump inhibitors: an exploration of awareness, attitude and behavior of health care professionals of Riyadh, Saudi Arabia. Saudi Pharm J. 2021, 29:713-8. 10.1016\/j.jsps.2021.04.033","journal-title":"Saudi Pharm J"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1592\/phco.23.13.74s.31929","article-title":"Pharmacologic properties of proton pump inhibitors","volume":"23","author":"Welage LS","year":"2003","unstructured":"Welage LS. Pharmacologic properties of proton pump inhibitors. Pharmacotherapy. 2003, 23:74S-80S. 10.1592\/phco.23.13.74s.31929","journal-title":"Pharmacotherapy"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp060393","article-title":"Stress ulcer prophylaxis in hospitalized patients not in intensive care units","volume":"64","author":"Grube RR","year":"2007","unstructured":"Grube RR, May DB. Stress ulcer prophylaxis in hospitalized patients not in intensive care units. Am J Health Syst Pharm. 2007, 64:1396-400. 10.2146\/ajhp060393","journal-title":"Am J Health Syst Pharm"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.12759","article-title":"Adverse effects associated with proton pump inhibitor use","volume":"13","author":"Yibirin M","year":"2021","unstructured":"Yibirin M, De Oliveira D, Valera R, Plitt AE, Lutgen S. Adverse effects associated with proton pump inhibitor use. Cureus. 2021, 13:e12759. 10.7759\/cureus.12759","journal-title":"Cureus"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v28.i24.2667","article-title":"Rebuilding trust in proton pump inhibitor therapy","volume":"28","author":"Turshudzhyan A","year":"2022","unstructured":"Turshudzhyan A, Samuel S, Tawfik A, Tadros M. Rebuilding trust in proton pump inhibitor therapy. World J Gastroenterol. 2022, 28:2667-79. 10.3748\/wjg.v28.i24.2667","journal-title":"World J Gastroenterol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4236\/pp.2018.96012","article-title":"Evaluation of appropriateness of proton pump inhibitors (PPIs) use in the region of Sharjah, United Arab Emirates (UAE)","volume":"9","author":"Mohamed Ibrahim OH","year":"2018","unstructured":"Mohamed Ibrahim OH, Rashrash MEA, Albasha R, et al.. Evaluation of appropriateness of proton pump inhibitors (PPIs) use in the region of Sharjah, United Arab Emirates (UAE). Pharmacology Pharm. 2018, 9:149-56. 10.4236\/pp.2018.96012","journal-title":"Pharmacology Pharm"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1383698","article-title":"Physicians' perceptions and awareness of adverse effects of proton pump inhibitors and impact on prescribing patterns","volume":"15","author":"Awad A","year":"2024","unstructured":"Awad A, Al-Tunaib A, Al-Saraf S. Physicians' perceptions and awareness of adverse effects of proton pump inhibitors and impact on prescribing patterns. Front Pharmacol. 2024, 15:1383698. 10.3389\/fphar.2024.1383698","journal-title":"Front Pharmacol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.5742\/MEWFM.2021.94184","article-title":"Proton pump inhibitors awareness among physicians and pharmacists in primary healthcare centres in Abha, Saudi Arabia","volume":"19","author":"Alasmari IH","year":"2021","unstructured":"Alasmari IH, Al Saleh MM, Alahmari MA, et al.. Proton pump inhibitors awareness among physicians and pharmacists in primary healthcare centres in Abha, Saudi Arabia. World Fam Med. 2021, 19:80-7. 10.5742\/MEWFM.2021.94184","journal-title":"World Fam Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13023","article-title":"Side effects of long-term proton pump inhibitor use: a review","volume":"123","author":"Haastrup PF","year":"2018","unstructured":"Haastrup PF, Thompson W, S\u00f8ndergaard J, Jarb\u00f8l DE. Side effects of long-term proton pump inhibitor use: a review. Basic Clin Pharmacol Toxicol. 2018, 123:114-21. 10.1111\/bcpt.13023","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15385","article-title":"Proton-pump inhibitors and long-term risk of community-acquired pneumonia in older adults","volume":"66","author":"Zirk-Sadowski J","year":"2018","unstructured":"Zirk-Sadowski J, Masoli JA, Delgado J, et al.. Proton-pump inhibitors and long-term risk of community-acquired pneumonia in older adults. J Am Geriatr Soc. 2018, 66:1332-8. 10.1111\/jgs.15385","journal-title":"J Am Geriatr Soc"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-015-3365-x","article-title":"Proton-pump inhibitors and risk of fractures: an update meta-analysis","volume":"27","author":"Zhou B","year":"2016","unstructured":"Zhou B, Huang Y, Li H, Sun W, Liu J. Proton-pump inhibitors and risk of fractures: an update meta-analysis. Osteoporos Int. 2016, 27:339-47. 10.1007\/s00198-015-3365-x","journal-title":"Osteoporos Int"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.20452\/pamw.15997","article-title":"Side effects of long-term use of proton pump inhibitors: practical considerations","volume":"131","author":"Castellana C","year":"2021","unstructured":"Castellana C, Pecere S, Furnari M, Telese A, Matteo MV, Haidry R, Eusebi LH. Side effects of long-term use of proton pump inhibitors: practical considerations. Pol Arch Intern Med. 2021, 131:541-9. 10.20452\/pamw.15997","journal-title":"Pol Arch Intern Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.179","article-title":"Clostridium difficile-associated diarrhea and proton pump inhibitor therapy: a meta-analysis","volume":"107","author":"Janarthanan S","year":"2012","unstructured":"Janarthanan S, Ditah I, Adler DG, Ehrinpreis MN. Clostridium difficile-associated diarrhea and proton pump inhibitor therapy: a meta-analysis. Am J Gastroenterol. 2012, 107:1001-10. 10.1038\/ajg.2012.179","journal-title":"Am J Gastroenterol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-014-0554-0","article-title":"Risk of dementia in elderly patients with the use of proton pump inhibitors","volume":"265","author":"Haenisch B","year":"2015","unstructured":"Haenisch B, von Holt K, Wiese B, et al.. Risk of dementia in elderly patients with the use of proton pump inhibitors. Eur Arch Psychiatry Clin Neurosci. 2015, 265:419-28. 10.1007\/s00406-014-0554-0","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2018.08.035","article-title":"Use of proton pump inhibitors and risk of ischemic events in the general population","volume":"277","author":"Casula M","year":"2018","unstructured":"Casula M, Scotti L, Galimberti F, Mozzanica F, Tragni E, Corrao G, Catapano AL. Use of proton pump inhibitors and risk of ischemic events in the general population. Atherosclerosis. 2018, 277:123-9. 10.1016\/j.atherosclerosis.2018.08.035","journal-title":"Atherosclerosis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.18-584","article-title":"Real-world relationship between proton pump inhibitors and cerebro-cardiovascular outcomes independent of clopidogrel: a meta-analysis of observational studies","volume":"60","author":"Li S","year":"2019","unstructured":"Li S, Liu F, Chen C, et al.. Real-world relationship between proton pump inhibitors and cerebro-cardiovascular outcomes independent of clopidogrel: a meta-analysis of observational studies. Int Heart J. 2019, 60:910-8. 10.1536\/ihj.18-584","journal-title":"Int Heart J"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v28i6.15","article-title":"Factors influencing prescribing decisions of physicians: a review","volume":"28","author":"Davari M","year":"2018","unstructured":"Davari M, Khorasani E, Tigabu BM. Factors influencing prescribing decisions of physicians: a review. Ethiop J Health Sci. 2018, 28:795-804. 10.4314\/ejhs.v28i6.15","journal-title":"Ethiop J Health Sci"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-019-4725-6","article-title":"Awareness, attitude and behavior regarding proton pump inhibitor among medical staff in the Southwest of China","volume":"19","author":"Luo H","year":"2019","unstructured":"Luo H, Fan Q, Bian T, et al.. Awareness, attitude and behavior regarding proton pump inhibitor among medical staff in the Southwest of China. BMC Health Serv Res. 2019, 19:880. 10.1186\/s12913-019-4725-6","journal-title":"BMC Health Serv Res"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.37184\/lnjpc.2707-3521.7.26","article-title":"Knowledge, attitudes, and practices regarding proton pump inhibitor utilization among primary care doctors in Muscat Governorate, Oman","volume":"7","author":"Al\u2011Jassasi K","year":"2025","unstructured":"Al\u2011Jassasi K, Al\u2011Hosni M, Al-Ghafri M, et al.. Knowledge, attitudes, and practices regarding proton pump inhibitor utilization among primary care doctors in Muscat Governorate, Oman. Liaquat Natl J Prim Care. 2025, 7:91-8. 10.37184\/lnjpc.2707-3521.7.26","journal-title":"Liaquat Natl J Prim Care"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/479799-knowledge-attitudes-and-prescribing-practices-of-primary-healthcare-physicians-regarding-proton-pump-inhibitor-use-in-the-united-arab-emirates-a-cross-sectional-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T07:35:04Z","timestamp":1775115304000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/479799-knowledge-attitudes-and-prescribing-practices-of-primary-healthcare-physicians-regarding-proton-pump-inhibitor-use-in-the-united-arab-emirates-a-cross-sectional-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,2]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.106308","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,2]]}}}