{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T02:52:14Z","timestamp":1776048734583,"version":"3.50.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,12]]},"DOI":"10.7759\/cureus.106917","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T02:34:22Z","timestamp":1776047662000},"source":"Crossref","is-referenced-by-count":0,"title":["Orthognathic Surgery Using 1-Desamino-8-D-Arginine Vasopressin (DDAVP) in a Patient With Von Willebrand Disease: A Case Report"],"prefix":"10.7759","author":[{"given":"Satoshi","family":"Usuda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Shiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taneaki","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Asoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s10006-013-0415-4","article-title":"Intraoperative blood loss and blood transfusion requirements in patients undergoing orthognathic surgery","volume":"18","author":"Faverani LP","year":"2014","unstructured":"Faverani LP, Ramalho-Ferreira G, Fabris AL, et al.. Intraoperative blood loss and blood transfusion requirements in patients undergoing orthognathic surgery. Oral Maxillofac Surg. 2014, 18:305-10. 10.1007\/s10006-013-0415-4","journal-title":"Oral Maxillofac Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2012.077263","article-title":"Principles of care for the diagnosis and treatment of von Willebrand disease","volume":"98","author":"Castaman G","year":"2013","unstructured":"Castaman G, Goodeve A, Eikenboom J. Principles of care for the diagnosis and treatment of von Willebrand disease. Haematologica. 2013, 98:667-74. 10.3324\/haematol.2012.077263","journal-title":"Haematologica"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199801000-00006","article-title":"Perioperative management of von Willebrand's disease in otolaryngologic surgery","volume":"108","author":"Shah SB","year":"1998","unstructured":"Shah SB, Lalwani AK, Koerper MA. Perioperative management of von Willebrand's disease in otolaryngologic surgery. Laryngoscope. 1998, 108:32-6. 10.1097\/00005537-199801000-00006","journal-title":"Laryngoscope"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-10-462085","article-title":"Alloantibodies in von Willebrand disease","volume":"122","author":"James PD","year":"2013","unstructured":"James PD, Lillicrap D, Mannucci PM. Alloantibodies in von Willebrand disease. Blood. 2013, 122:636-40. 10.1182\/blood-2012-10-462085","journal-title":"Blood"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-09-455089","article-title":"VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease","volume":"121","author":"Eikenboom J","year":"2013","unstructured":"Eikenboom J, Federici AB, Dirven RJ, et al.. VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease. Blood. 2013, 121:2336-9. 10.1182\/blood-2012-09-455089","journal-title":"Blood"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s40902-022-00345-7","article-title":"Clinical investigation of patients with jaw deformity with comorbidities","volume":"44","author":"Kasahara K","year":"2022","unstructured":"Kasahara K, Hoshino T, Sugiura K, et al.. Clinical investigation of patients with jaw deformity with comorbidities. Maxillofac Plast Reconstr Surg. 2022, 44:15. 10.1186\/s40902-022-00345-7","journal-title":"Maxillofac Plast Reconstr Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3476(05)80384-1","article-title":"Prevalence of von Willebrand disease in children: a multiethnic study","volume":"123","author":"Werner EJ","year":"1993","unstructured":"Werner EJ, Broxson EH, Tucker EL, Giroux DS, Shults J, Abshire TC. Prevalence of von Willebrand disease in children: a multiethnic study. J Pediatr. 1993, 123:893-8. 10.1016\/s0022-3476(05)80384-1","journal-title":"J Pediatr"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12254","article-title":"Desmopressin (DDAVP) in the management of patients with congenital bleeding disorders","volume":"20","author":"Leissinger C","year":"2014","unstructured":"Leissinger C, Carcao M, Gill JC, Journeycake J, Singleton T, Valentino L. Desmopressin (DDAVP) in the management of patients with congenital bleeding disorders. Haemophilia. 2014, 20:158-67. 10.1111\/hae.12254","journal-title":"Haemophilia"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/s0266-4356(98)90178-4","article-title":"von Willebrand disease and its management in oral and maxillofacial surgery","volume":"36","author":"Wilde JT","year":"1998","unstructured":"Wilde JT, Cook RJ. von Willebrand disease and its management in oral and maxillofacial surgery. Br J Oral Maxillofac Surg. 1998, 36:112-8. 10.1016\/s0266-4356(98)90178-4","journal-title":"Br J Oral Maxillofac Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198310063091402","article-title":"Platelet aggregation induced by 1-desamino-8-D-arginine vasopressin (DDAVP) in type IIB von Willebrand's disease","volume":"309","author":"Holmberg L","year":"1983","unstructured":"Holmberg L, Nilsson IM, Borge L, Gunnarsson M, Sj\u00f6rin E. Platelet aggregation induced by 1-desamino-8-D-arginine vasopressin (DDAVP) in type IIB von Willebrand's disease. N Engl J Med. 1983, 309:816-21. 10.1056\/NEJM198310063091402","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-08-551960","article-title":"How I treat type 2 variant forms of von Willebrand disease","volume":"125","author":"Tosetto A","year":"2015","unstructured":"Tosetto A, Castaman G. How I treat type 2 variant forms of von Willebrand disease. Blood. 2015, 125:907-14. 10.1182\/blood-2014-08-551960","journal-title":"Blood"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2002.121431","article-title":"Management of dental extractions in patients with bleeding disorders","volume":"93","author":"Piot B","year":"2002","unstructured":"Piot B, Sigaud-Fiks M, Huet P, Fressinaud E, Trossa\u00ebrt M, Mercier J. Management of dental extractions in patients with bleeding disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002, 93:247-50. 10.1067\/moe.2002.121431","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12809","article-title":"Von Willebrand disease - the 'dos' and 'don'ts' in surgery","volume":"98","author":"Miesbach W","year":"2017","unstructured":"Miesbach W, Berntorp E. Von Willebrand disease - the 'dos' and 'don'ts' in surgery. Eur J Haematol. 2017, 98:121-7. 10.1111\/ejh.12809","journal-title":"Eur J Haematol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/0266-4356(90)90038-m","article-title":"Correction of facial deformities in patients with mild bleeding disorders: a report of three cases","volume":"28","author":"Ilankovan V","year":"1990","unstructured":"Ilankovan V, Blesing NE, Moos KF, Davidson JF. Correction of facial deformities in patients with mild bleeding disorders: a report of three cases. Br J Oral Maxillofac Surg. 1990, 28:398-400. 10.1016\/0266-4356(90)90038-m","journal-title":"Br J Oral Maxillofac Surg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(92)90314-g","article-title":"Preoperative laboratory assessment of hemostasis for orthognathic surgery","volume":"73","author":"Holtzman LS","year":"1992","unstructured":"Holtzman LS, Burns ER, Kraut RA. Preoperative laboratory assessment of hemostasis for orthognathic surgery. Oral Surg Oral Med Oral Pathol. 1992, 73:403-6. 10.1016\/0030-4220(92)90314-g","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.57305","article-title":"Orthognathic surgery in patients with von Willebrand\u2019s disease: a report of four cases and literature review","volume":"16","author":"Sato M","year":"2024","unstructured":"Sato M, Hamada H, Hasegawa O, Kawase-Koga Y, Chikazu D. Orthognathic surgery in patients with von Willebrand\u2019s disease: a report of four cases and literature review. Cureus. 2024, 16:57305. 10.7759\/cureus.57305","journal-title":"Cureus"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V90.7.2515","article-title":"Desmopressin (DDAVP) in the treatment of bleeding disorders: the first 20 years","volume":"90","author":"Mannucci PM","year":"1997","unstructured":"Mannucci PM. Desmopressin (DDAVP) in the treatment of bleeding disorders: the first 20 years. Blood. 1997, 90:2515-21. 10.1182\/blood.V90.7.2515","journal-title":"Blood"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2015.05.031","article-title":"Prevention of bleeding in orthognathic surgery-a systematic review and meta-analysis of randomized controlled trials","volume":"74","author":"Olsen JJ","year":"2016","unstructured":"Olsen JJ, Skov J, Ingerslev J, Thorn JJ, Pinholt EM. Prevention of bleeding in orthognathic surgery-a systematic review and meta-analysis of randomized controlled trials. J Oral Maxillofac Surg. 2016, 74:139-50. 10.1016\/j.joms.2015.05.031","journal-title":"J Oral Maxillofac Surg"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2010.07.019","article-title":"Blood loss in orthognathic surgery: a systematic review","volume":"69","author":"Pi\u00f1eiro-Aguilar A","year":"2011","unstructured":"Pi\u00f1eiro-Aguilar A, Somoza-Mart\u00edn M, Gandara-Rey JM, Garc\u00eda-Garc\u00eda A. Blood loss in orthognathic surgery: a systematic review. J Oral Maxillofac Surg. 2011, 69:885-92. 10.1016\/j.joms.2010.07.019","journal-title":"J Oral Maxillofac Surg"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.02.085","article-title":"Factors that determine intraoperative blood loss in bimaxillary osteotomies and the need for preoperative blood preparation","volume":"69","author":"Rummasak D","year":"2011","unstructured":"Rummasak D, Apipan B, Kaewpradup P. Factors that determine intraoperative blood loss in bimaxillary osteotomies and the need for preoperative blood preparation. J Oral Maxillofac Surg. 2011, 69:456-60. 10.1016\/j.joms.2011.02.085","journal-title":"J Oral Maxillofac Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/389132-orthognathic-surgery-using-1-desamino-8-d-arginine-vasopressin-ddavp-in-a-patient-with-von-willebrand-disease-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T02:34:25Z","timestamp":1776047665000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/389132-orthognathic-surgery-using-1-desamino-8-d-arginine-vasopressin-ddavp-in-a-patient-with-von-willebrand-disease-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,12]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.106917","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,12]]}}}