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Vitamin D receptor gene polymorphisms among Emirati patients with type 2 diabetes mellitus. J Steroid Biochem Mol Biol. 2018, 175:119-24. 10.1016\/j.jsbmb.2017.03.012","journal-title":"J Steroid Biochem Mol Biol"},{"key":"ref54","article-title":"Vitamin D receptor gene polymorphisms and vitamin D status and susceptibility to type 2 diabetes mellitus in Moroccan patients","volume":"4","author":"Errouagui A","year":"2014","unstructured":"Errouagui A, Benrahma H, Charoute H, Barakat H, Kandil M, Rouba H. Vitamin D receptor gene polymorphisms and vitamin D status and susceptibility to type 2 diabetes mellitus in Moroccan patients. Int J Sci Res Publ. 2014, 4:1-8.","journal-title":"Int J Sci Res Publ"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2013.02.002","article-title":"Vitamin D receptor gene polymorphisms and type 2 diabetes: a meta-analysis","volume":"44","author":"Li L","year":"2013","unstructured":"Li L, Wu B, Liu JY, Yang LB. Vitamin D receptor gene polymorphisms and type 2 diabetes: a meta-analysis. Arch Med Res. 2013, 44:235-41. 10.1016\/j.arcmed.2013.02.002","journal-title":"Arch Med Res"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1515\/dmdi-2020-0178","article-title":"Association of genetic polymorphisms in vitamin D receptor (ApaI, TaqI and FokI) with vitamin D and glycemic status in type 2 diabetes patients from Southern India","volume":"36","author":"Selvarajan S","year":"2021","unstructured":"Selvarajan S, Srinivasan A, Surendran D, Mathaiyan J, Kamalanathan S. Association of genetic polymorphisms in vitamin D receptor (ApaI, TaqI and FokI) with vitamin D and glycemic status in type 2 diabetes patients from Southern India. Drug Metab Pers Ther. 2021, 36:183-7. 10.1515\/dmdi-2020-0178","journal-title":"Drug Metab Pers Ther"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.3390\/biology9080222","article-title":"Artificial neural networks model for predicting type 2 diabetes mellitus based on VDR gene FokI polymorphism, lipid profile and demographic data","volume":"9","author":"Hatmal MM","year":"2020","unstructured":"Hatmal MM, Abderrahman SM, Nimer W, et al.. Artificial neural networks model for predicting type 2 diabetes mellitus based on VDR gene FokI polymorphism, lipid profile and demographic data. Biology (Basel). 2020, 9:222. 10.3390\/biology9080222","journal-title":"Biology (Basel)"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-012-1805-7","article-title":"Quantitative assessment of the associations between four polymorphisms (FokI, ApaI, BsmI, TaqI) of vitamin D receptor gene and risk of diabetes mellitus","volume":"39","author":"Wang Q","year":"2012","unstructured":"Wang Q, Xi B, Reilly KH, Liu M, Fu M. Quantitative assessment of the associations between four polymorphisms (FokI, ApaI, BsmI, TaqI) of vitamin D receptor gene and risk of diabetes mellitus. Mol Biol Rep. 2012, 39:9405-14. 10.1007\/s11033-012-1805-7","journal-title":"Mol Biol Rep"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-023-04503-2","article-title":"The effect of BsmI (rs1544410) single nucleotide polymorphism of vitamin D receptor (VDR) on insulin resistance in healthy children and adolescents: a cross-sectional study","volume":"24","author":"Gholami A","year":"2024","unstructured":"Gholami A, Montazeri-Najafabady N, Karimzadeh I, Dabbaghmanesh MH, Talei E. The effect of BsmI (rs1544410) single nucleotide polymorphism of vitamin D receptor (VDR) on insulin resistance in healthy children and adolescents: a cross-sectional study. BMC Pediatr. 2024, 24:54. 10.1186\/s12887-023-04503-2","journal-title":"BMC Pediatr"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.41718","article-title":"The effect of vitamin D supplementation on the glycemic status and the percentage of body fat mass in adults with prediabetes: a randomized clinical trial","volume":"19","author":"Zarrin R","year":"2024","unstructured":"Zarrin R, Ayremlou P, Ghassemi F. The effect of vitamin D supplementation on the glycemic status and the percentage of body fat mass in adults with prediabetes: a randomized clinical trial. Iranian Red Crescent Med J. 2024, 19:1-8. 10.5812\/ircmj.41718","journal-title":"Iranian Red Crescent Med J"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.871571","article-title":"Severe 25-hydroxyvitamin D deficiency may predict poor renal outcomes in patients with biopsy-proven diabetic nephropathy","volume":"13","author":"Zhou T","year":"2022","unstructured":"Zhou T, Shen L, Li Z, et al.. Severe 25-hydroxyvitamin D deficiency may predict poor renal outcomes in patients with biopsy-proven diabetic nephropathy. 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