{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T12:05:45Z","timestamp":1776081945680,"version":"3.50.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,13]]},"DOI":"10.7759\/cureus.106942","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T11:23:47Z","timestamp":1776079427000},"source":"Crossref","is-referenced-by-count":0,"title":["Baclofen in Refractory Dyspepsia With Chronic Belching: A Case Report"],"prefix":"10.7759","author":[{"given":"Mariana","family":"Rocha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisete","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-307843","article-title":"Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis","volume":"64","author":"Ford AC","year":"2015","unstructured":"Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2015, 64:1049-57. 10.1136\/gutjnl-2014-307843","journal-title":"Gut"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.032","article-title":"Functional gastrointestinal disorders: history, pathophysiology, clinical features and Rome IV","volume":"4","author":"Drossman DA","year":"2016","unstructured":"Drossman DA. Functional gastrointestinal disorders: history, pathophysiology, clinical features and Rome IV. Gastroenterology. 2016, 4:14-6. 10.1053\/j.gastro.2016.02.032","journal-title":"Gastroenterology"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.11.279","article-title":"Neuromodulators for functional gastrointestinal disorders (disorders of gut-brain interaction): a Rome Foundation working team report","volume":"154","author":"Drossman DA","year":"2018","unstructured":"Drossman DA, Tack J, Ford AC, Szigethy E, T\u00f6rnblom H, Van Oudenhove L. Neuromodulators for functional gastrointestinal disorders (disorders of gut-brain interaction): a Rome Foundation working team report. Gastroenterology. 2018, 154:1140-71. 10.1053\/j.gastro.2017.11.279","journal-title":"Gastroenterology"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30469-4","article-title":"Functional dyspepsia","volume":"396","author":"Ford AC","year":"2020","unstructured":"Ford AC, Mahadeva S, Carbone MF, Lacy BE, Talley NJ. Functional dyspepsia. Lancet. 2020, 396:1689-02. 10.1016\/S0140-6736(20)30469-4","journal-title":"Lancet"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2023-331835","article-title":"Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis","volume":"73","author":"Porcari S","year":"2024","unstructured":"Porcari S, Ingrosso MR, Maida M, et al.. Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis. Gut. 2024, 73:1431-40. 10.1136\/gutjnl-2023-331835","journal-title":"Gut"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2022-327737","article-title":"British Society of Gastroenterology guidelines on the management of functional dyspepsia","volume":"71","author":"Black CJ","year":"2022","unstructured":"Black CJ, Paine PA, Agrawal A, et al.. British Society of Gastroenterology guidelines on the management of functional dyspepsia. Gut. 2022, 71:1697-723. 10.1136\/gutjnl-2022-327737","journal-title":"Gut"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4166\/kjg.2014.64.1.4","article-title":"Belching (eructation) (Article in Korean)","volume":"64","author":"Ryu HS","year":"2014","unstructured":"Ryu HS, Choi SC, Lee JS. Belching (eructation) (Article in Korean). Korean J Gastroenterol. 2014, 64:4-9. 10.4166\/kjg.2014.64.1.4","journal-title":"Korean J Gastroenterol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/apt.70189","article-title":"Functional dyspepsia and its subgroups: prevalence and impact in the Rome IV global epidemiology study","volume":"62","author":"Tack J","year":"2025","unstructured":"Tack J, Palsson OS, Bangdiwala SI, et al.. Functional dyspepsia and its subgroups: prevalence and impact in the Rome IV global epidemiology study. Aliment Pharmacol Ther. 2025, 62:330-9. 10.1111\/apt.70189","journal-title":"Aliment Pharmacol Ther"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.154","article-title":"ACG and CAG clinical guideline: management of dyspepsia","volume":"112","author":"Moayyedi P","year":"2017","unstructured":"Moayyedi P, Lacy BE, Andrews CN, Enns RA, Howden CW, Vakil N. ACG and CAG clinical guideline: management of dyspepsia. Am J Gastroenterol. 2017, 112:988-1013. 10.1038\/ajg.2017.154","journal-title":"Am J Gastroenterol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.09.019","article-title":"American Gastroenterological Association medical position statement: evaluation of dyspepsia","volume":"129","author":"Talley NJ","year":"2005","unstructured":"Talley NJ. American Gastroenterological Association medical position statement: evaluation of dyspepsia. Gastroenterology. 2005, 129:1753-5. 10.1053\/j.gastro.2005.09.019","journal-title":"Gastroenterology"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011194.pub3","article-title":"Proton pump inhibitors for functional dyspepsia","volume":"11","author":"Pinto-Sanchez MI","year":"2017","unstructured":"Pinto-Sanchez MI, Yuan Y, Hassan A, Bercik P, Moayyedi P. Proton pump inhibitors for functional dyspepsia. Cochrane Database Syst Rev. 2017, 11:CD011194. 10.1002\/14651858.CD011194.pub3","journal-title":"Cochrane Database Syst Rev"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9343(99)00299-5","article-title":"Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis","volume":"108","author":"Jackson JL","year":"2000","unstructured":"Jackson JL, O'Malley PG, Tomkins G, Balden E, Santoro J, Kroenke K. Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis. Am J Med. 2000, 108:65-72. 10.1016\/s0002-9343(99)00299-5","journal-title":"Am J Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301897","article-title":"Diagnosis and management of patients with reflux symptoms refractory to proton pump inhibitors","volume":"61","author":"Sifrim D","year":"2012","unstructured":"Sifrim D, Zerbib F. Diagnosis and management of patients with reflux symptoms refractory to proton pump inhibitors. Gut. 2012, 61:1340-54. 10.1136\/gutjnl-2011-301897","journal-title":"Gut"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.10.042","article-title":"Baclofen improves symptoms and reduces postprandial flow events in patients with rumination and supragastric belching","volume":"10","author":"Blondeau K","year":"2012","unstructured":"Blondeau K, Boecxstaens V, Rommel N, et al.. Baclofen improves symptoms and reduces postprandial flow events in patients with rumination and supragastric belching. Clin Gastroenterol Hepatol. 2012, 10:379-84. 10.1016\/j.cgh.2011.10.042","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-020-00276-0","article-title":"Chronic burping and belching","volume":"18","author":"Zad M","year":"2020","unstructured":"Zad M, Bredenoord AJ. Chronic burping and belching. Curr Treat Options Gastroenterol. 2020, 18:33-42. 10.1007\/s11938-020-00276-0","journal-title":"Curr Treat Options Gastroenterol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/pcn.12223","article-title":"Successful treatment of excessive supragastric belching by combination of pregabalin and baclofen","volume":"69","author":"Kunte H","year":"2015","unstructured":"Kunte H, Kronenberg G, Fink K, Harms L, Hellweg R. Successful treatment of excessive supragastric belching by combination of pregabalin and baclofen. Psychiatry Clin Neurosci. 2015, 69:124-5. 10.1111\/pcn.12223","journal-title":"Psychiatry Clin Neurosci"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2023.101831","article-title":"Role of Low-FODMAP diet in functional dyspepsia: \"Why\", \"When\", and \"to Whom\"","volume":"62","author":"Rettura F","year":"2023","unstructured":"Rettura F, Lambiase C, Grosso A, Rossi A, Tedeschi R, Ceccarelli L, Bellini M. Role of Low-FODMAP diet in functional dyspepsia: \"Why\", \"When\", and \"to Whom\". Best Pract Res Clin Gastroenterol. 2023, 62:101831. 10.1016\/j.bpg.2023.101831","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.01.045","article-title":"Best practice update: incorporating psychogastroenterology into management of digestive disorders","volume":"154","author":"Keefer L","year":"2018","unstructured":"Keefer L, Palsson OS, Pandolfino JE. Best practice update: incorporating psychogastroenterology into management of digestive disorders. Gastroenterology. 2018, 154:1249-57. 10.1053\/j.gastro.2018.01.045","journal-title":"Gastroenterology"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/476406-baclofen-in-refractory-dyspepsia-with-chronic-belching-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T11:23:48Z","timestamp":1776079428000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/476406-baclofen-in-refractory-dyspepsia-with-chronic-belching-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,13]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.106942","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,13]]}}}