{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T22:38:51Z","timestamp":1776638331107,"version":"3.51.2"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,19]]},"DOI":"10.7759\/cureus.107358","type":"journal-article","created":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T21:46:58Z","timestamp":1776635218000},"source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of Laparoscopic Versus Open Lateral Lymph Node Dissection Following Total Mesorectal Excision for Advanced Rectal Cancer: A Systematic Review and Meta-Analysis"],"prefix":"10.7759","author":[{"given":"Rubens","family":"Rigo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinnicius","family":"Duarte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo F","family":"Pompeu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Formiga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16081530","article-title":"Colorectal cancer: epidemiology, risk factors, and prevention","volume":"16","author":"Roshandel G","year":"2024","unstructured":"Roshandel G, Ghasemi-Kebria F, Malekzadeh R. Colorectal cancer: epidemiology, risk factors, and prevention. Cancers (Basel). 2024, 16:1530. 10.3390\/cancers16081530","journal-title":"Cancers (Basel)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2022-327736","article-title":"Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN","volume":"72","author":"Morgan E","year":"2023","unstructured":"Morgan E, Arnold M, Gini A, et al.. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut. 2023, 72:338-44. 10.1136\/gutjnl-2022-327736","journal-title":"Gut"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v13.i10.1412","article-title":"Lateral pelvic lymph nodes for rectal cancer: a review of diagnosis and management","volume":"13","author":"Ogawa S","year":"2021","unstructured":"Ogawa S, Itabashi M, Inoue Y, et al.. Lateral pelvic lymph nodes for rectal cancer: a review of diagnosis and management. World J Gastrointest Oncol. 2021, 13:1412-24. 10.4251\/wjgo.v13.i10.1412","journal-title":"World J Gastrointest Oncol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2020.0032","article-title":"NCCN guidelines insights: rectal cancer, version 6.2020","volume":"18","author":"Benson AB","year":"2020","unstructured":"Benson AB, Venook AP, Al-Hawary MM, et al.. NCCN guidelines insights: rectal cancer, version 6.2020. J Natl Compr Canc Netw. 2020, 18:806-15. 10.6004\/jnccn.2020.0032","journal-title":"J Natl Compr Canc Netw"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-019-01485-z","article-title":"Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer","volume":"25","author":"Hashiguchi Y","year":"2020","unstructured":"Hashiguchi Y, Muro K, Saito Y, et al.. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer. Int J Clin Oncol. 2020, 25:1-42. 10.1007\/s10147-019-01485-z","journal-title":"Int J Clin Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2020.06.010","article-title":"Postoperative morbidity and mortality after mesorectal excision with laparoscopic versus conventional open lateral lymph node dissection for advanced rectal cancer: a meta-analysis","volume":"44","author":"Du R","year":"2021","unstructured":"Du R, Zhou J, Li D, et al.. Postoperative morbidity and mortality after mesorectal excision with laparoscopic versus conventional open lateral lymph node dissection for advanced rectal cancer: a meta-analysis. Asian J Surg. 2021, 44:26-35. 10.1016\/j.asjsur.2020.06.010","journal-title":"Asian J Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.26633\/RPSP.2022.112","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews (Article in Portuguese)","volume":"46","author":"Page MJ","year":"2022","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, et al.. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews (Article in Portuguese). Rev Panam Salud Publica. 2022, 46:112. 10.26633\/RPSP.2022.112","journal-title":"Rev Panam Salud Publica"},{"key":"ref8","article-title":"Outcomes of laparoscopic versus open lateral lymph node dissection following total mesorectal excision for advanced rectal cancer: a systematic review and meta-analysis","author":"Duarte V","year":"2025","unstructured":"Duarte V, Alves LEBM, Rigo RSM, et al.. Outcomes of laparoscopic versus open lateral lymph node dissection following total mesorectal excision for advanced rectal cancer: a systematic review and meta-analysis. PROSPERO. 2025,","journal-title":"PROSPERO"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne JA","year":"2016","unstructured":"Sterne JA, Hern\u00e1n MA, Reeves BC, et al.. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016, 355:4919. 10.1136\/bmj.i4919","journal-title":"BMJ"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/codi.16223","article-title":"Short- and long-term outcomes of laparoscopic versus open selective lateral pelvic lymph node dissection for locally advanced middle-low rectal cancer: results of a multicentre lateral node study in China","volume":"24","author":"Tang J","year":"2022","unstructured":"Tang J, Zhou S, Zhao W, et al.. Short- and long-term outcomes of laparoscopic versus open selective lateral pelvic lymph node dissection for locally advanced middle-low rectal cancer: results of a multicentre lateral node study in China. Colorectal Dis. 2022, 24:1325-34. 10.1111\/codi.16223","journal-title":"Colorectal Dis"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrac068","article-title":"Laparoscopic versus open lateral pelvic lymph node dissection in locally advanced rectal cancer: multicentre retrospective cohort study","volume":"6","author":"Lim HK","year":"2022","unstructured":"Lim HK, Kim M, Park JW, et al.. Laparoscopic versus open lateral pelvic lymph node dissection in locally advanced rectal cancer: multicentre retrospective cohort study. BJS Open. 2022, 6:068. 10.1093\/bjsopen\/zrac068","journal-title":"BJS Open"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/ans.17252","article-title":"Open versus laparoscopic lateral lymph node dissection for mid- and low- rectal cancer: a propensity score matching study","volume":"91","author":"Zhang Y","year":"2021","unstructured":"Zhang Y, Yang X, Wang D, et al.. Open versus laparoscopic lateral lymph node dissection for mid- and low- rectal cancer: a propensity score matching study. ANZ J Surg. 2021, 91:2487-92. 10.1111\/ans.17252","journal-title":"ANZ J Surg"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-020-03609-8","article-title":"Laparoscopic versus open selective lateral pelvic lymph node dissection following total mesorectal excision for locally advanced low rectal cancer","volume":"35","author":"Yang B","year":"2020","unstructured":"Yang B, Huang J, Zhou S, Tan J, Zhong G, Gao H, Han F. Laparoscopic versus open selective lateral pelvic lymph node dissection following total mesorectal excision for locally advanced low rectal cancer. Int J Colorectal Dis. 2020, 35:1301-9. 10.1007\/s00384-020-03609-8","journal-title":"Int J Colorectal Dis"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000843","article-title":"Laparoscopic versus open lateral lymph node dissection for locally advanced low rectal cancer: a subgroup analysis of a large multicenter cohort study in Japan","volume":"60","author":"Yamaguchi T","year":"2017","unstructured":"Yamaguchi T, Konishi T, Kinugasa Y, et al.. Laparoscopic versus open lateral lymph node dissection for locally advanced low rectal cancer: a subgroup analysis of a large multicenter cohort study in Japan. Dis Colon Rectum. 2017, 60:954-64. 10.1097\/DCR.0000000000000843","journal-title":"Dis Colon Rectum"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.11927","article-title":"Clinical and oncological outcomes of laparoscopic lateral pelvic lymph node dissection in advanced lower rectal cancer: single-institution experience","volume":"37","author":"Nonaka T","year":"2017","unstructured":"Nonaka T, Fukuda A, Maekawa K, et al.. Clinical and oncological outcomes of laparoscopic lateral pelvic lymph node dissection in advanced lower rectal cancer: single-institution experience. Anticancer Res. 2017, 37:5095-100. 10.21873\/anticanres.11927","journal-title":"Anticancer Res"},{"key":"ref16","article-title":"Short-term outcomes of laparoscopic lateral dissection for lower rectal cancer","volume":"67","author":"Mohohashi H","year":"2016","unstructured":"Mohohashi H, Sakamoto Y, Ichinohe D, et al.. Short-term outcomes of laparoscopic lateral dissection for lower rectal cancer. Hirosaki Med J. 2016, 67:86-91.","journal-title":"Hirosaki Med J"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-5014-7","article-title":"A technique of laparoscopic lateral pelvic lymph node dissection based on vesicohypogastric fascia and ureterohypogastric nerve fascia for advanced low rectal cancer","volume":"31","author":"Matsumoto A","year":"2017","unstructured":"Matsumoto A, Arita K. A technique of laparoscopic lateral pelvic lymph node dissection based on vesicohypogastric fascia and ureterohypogastric nerve fascia for advanced low rectal cancer. Surg Endosc. 2017, 31:945-8. 10.1007\/s00464-016-5014-7","journal-title":"Surg Endosc"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-020-07943-4","article-title":"Short- and long-term outcomes of laparoscopic versus open lateral lymph node dissection for locally advanced middle\/lower rectal cancer using a propensity score-matched analysis","volume":"35","author":"Watanabe J","year":"2021","unstructured":"Watanabe J, Ishibe A, Suwa Y, et al.. Short- and long-term outcomes of laparoscopic versus open lateral lymph node dissection for locally advanced middle\/lower rectal cancer using a propensity score-matched analysis. Surg Endosc. 2021, 35:4427-35. 10.1007\/s00464-020-07943-4","journal-title":"Surg Endosc"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7689082","article-title":"Laparoscopic versus open surgery in lateral lymph node dissection for advanced rectal cancer: a meta-analysis","volume":"2019","author":"Ouyang M","year":"2019","unstructured":"Ouyang M, Liao T, Lu Y, et al.. Laparoscopic versus open surgery in lateral lymph node dissection for advanced rectal cancer: a meta-analysis. Gastroenterol Res Pract. 2019, 2019:7689082. 10.1155\/2019\/7689082","journal-title":"Gastroenterol Res Pract"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2025.08.192","article-title":"Laparoscopic lateral lymph node dissection for locally advanced low rectal cancers: a technical note with video vignette","volume":"48","author":"Kyo K","year":"2025","unstructured":"Kyo K. Laparoscopic lateral lymph node dissection for locally advanced low rectal cancers: a technical note with video vignette. Asian J Surg. 2025, 48:6699-701. 10.1016\/j.asjsur.2025.08.192","journal-title":"Asian J Surg"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.94939","article-title":"Hemostasis in laparoscopic renal surgery","volume":"28","author":"Hassouna HA","year":"2012","unstructured":"Hassouna HA, Manikandan R. Hemostasis in laparoscopic renal surgery. Indian J Urol. 2012, 28:3-8. 10.4103\/0970-1591.94939","journal-title":"Indian J Urol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/01.TA.0000022460.21283.53","article-title":"Allogeneic blood transfusion increases the risk of postoperative bacterial infection: a meta-analysis","volume":"54","author":"Hill GE","year":"2003","unstructured":"Hill GE, Frawley WH, Griffith KE, Forestner JE, Minei JP. Allogeneic blood transfusion increases the risk of postoperative bacterial infection: a meta-analysis. J Trauma. 2003, 54:908-14. 10.1097\/01.TA.0000022460.21283.53","journal-title":"J Trauma"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13855","article-title":"Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness","volume":"57","author":"Muszynski JA","year":"2017","unstructured":"Muszynski JA, Spinella PC, Cholette JM, et al.. Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness. Transfusion. 2017, 57:195-206. 10.1111\/trf.13855","journal-title":"Transfusion"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2018.1.585","article-title":"TACO and TRALI: biology, risk factors, and prevention strategies","volume":"2018","author":"Roubinian N","year":"2018","unstructured":"Roubinian N. TACO and TRALI: biology, risk factors, and prevention strategies. Hematology Am Soc Hematol Educ Program. 2018, 2018:585-94. 10.1182\/asheducation-2018.1.585","journal-title":"Hematology Am Soc Hematol Educ Program"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/477693-outcomes-of-laparoscopic-versus-open-lateral-lymph-node-dissection-following-total-mesorectal-excision-for-advanced-rectal-cancer-a-systematic-review-and-meta-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T21:46:59Z","timestamp":1776635219000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/477693-outcomes-of-laparoscopic-versus-open-lateral-lymph-node-dissection-following-total-mesorectal-excision-for-advanced-rectal-cancer-a-systematic-review-and-meta-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,19]]},"references-count":24,"URL":"https:\/\/doi.org\/10.7759\/cureus.107358","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,19]]}}}