{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T09:24:07Z","timestamp":1776849847233,"version":"3.51.2"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,22]]},"DOI":"10.7759\/cureus.107520","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T08:25:41Z","timestamp":1776846341000},"source":"Crossref","is-referenced-by-count":0,"title":["Cesarean Delivery in a Patient With Segawa Syndrome (Dopamine-Responsive Dystonia) Under Epidural Anesthesia: A Case Report"],"prefix":"10.7759","author":[{"given":"Eunkyung","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeonseung","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juhee","family":"Min","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deokhee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2010.10.015","article-title":"Hereditary progressive dystonia with marked diurnal fluctuation","volume":"33","author":"Segawa M","year":"2011","unstructured":"Segawa M. Hereditary progressive dystonia with marked diurnal fluctuation. Brain Dev. 2011, 33:195-201. 10.1016\/j.braindev.2010.10.015","journal-title":"Brain Dev"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25244","article-title":"The prevalence of primary dystonia: a systematic review and meta-analysis","volume":"27","author":"Steeves TD","year":"2012","unstructured":"Steeves TD, Day L, Dykeman J, Jette N, Pringsheim T. The prevalence of primary dystonia: a systematic review and meta-analysis. Mov Disord. 2012, 27:1789-96. 10.1002\/mds.25244","journal-title":"Mov Disord"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/8154006","article-title":"Segawa syndrome, a dramatic response to dopamine","volume":"2024","author":"Dhungel O","year":"2024","unstructured":"Dhungel O, Shrestha A, Sharma P, Sapkota N, Paudel R. Segawa syndrome, a dramatic response to dopamine. Case Rep Neurol Med. 2024, 2024:8154006. 10.1155\/2024\/8154006","journal-title":"Case Rep Neurol Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-8180(97)00225-0","article-title":"The choice of anesthesia in Segawa's syndrome","volume":"10","author":"Priscu V","year":"1998","unstructured":"Priscu V, Lurie S, Savir I, Rabinerson D, Hagay Z. The choice of anesthesia in Segawa's syndrome. J Clin Anesth. 1998, 10:153-5. 10.1016\/S0952-8180(97)00225-0","journal-title":"J Clin Anesth"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2008.07.003","article-title":"Anaesthesia for caesarean section in a patient with dopa-responsive dystonia or Segawa's syndrome","volume":"18","author":"Sinha A","year":"2009","unstructured":"Sinha A, Hartsilver EL. Anaesthesia for caesarean section in a patient with dopa-responsive dystonia or Segawa's syndrome. Int J Obstet Anesth. 2009, 18:67-72. 10.1016\/j.ijoa.2008.07.003","journal-title":"Int J Obstet Anesth"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2013.10.013","article-title":"Two cases of pregnancy in Parkinson's disease","volume":"20","author":"Lamichhane D","year":"2014","unstructured":"Lamichhane D, Narayanan NS, Gonzalez-Alegre P. Two cases of pregnancy in Parkinson's disease. Parkinsonism Relat Disord. 2014, 20:239-40. 10.1016\/j.parkreldis.2013.10.013","journal-title":"Parkinsonism Relat Disord"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1590\/s0004-282x2007000700026","article-title":"A novel missense mutation pattern of the GCH1 gene in dopa-responsive dystonia","volume":"65","author":"Scola RH","year":"2007","unstructured":"Scola RH, Carducci C, Amaral VG, Lorenzoni PJ, Teive HA, Giovanniello T, Werneck LC. A novel missense mutation pattern of the GCH1 gene in dopa-responsive dystonia. Arq Neuropsiquiatr. 2007, 65:1224-7. 10.1590\/s0004-282x2007000700026","journal-title":"Arq Neuropsiquiatr"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10630","article-title":"Autosomal dominant guanosine triphosphate cyclohydrolase I deficiency (Segawa disease)","volume":"54 Suppl 6","author":"Segawa M","year":"2003","unstructured":"Segawa M, Nomura Y, Nishiyama N. Autosomal dominant guanosine triphosphate cyclohydrolase I deficiency (Segawa disease). Ann Neurol. 2003, 54 Suppl 6:S32-45. 10.1002\/ana.10630","journal-title":"Ann Neurol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000021753","article-title":"Dopa-responsive dystonia caused by tyrosine hydroxylase deficiency: three cases report and literature review","volume":"99","author":"Dong HY","year":"2020","unstructured":"Dong HY, Feng JY, Yue XJ, Shan L, Jia FY. Dopa-responsive dystonia caused by tyrosine hydroxylase deficiency: three cases report and literature review. Medicine (Baltimore). 2020, 99:e21753. 10.1097\/MD.0000000000021753","journal-title":"Medicine (Baltimore)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/humu.22565","article-title":"Functional studies of tyrosine hydroxylase missense variants reveal distinct patterns of molecular defects in dopa-responsive dystonia","volume":"35","author":"Fossbakk A","year":"2014","unstructured":"Fossbakk A, Kleppe R, Knappskog PM, Martinez A, Haavik J. Functional studies of tyrosine hydroxylase missense variants reveal distinct patterns of molecular defects in dopa-responsive dystonia. Hum Mutat. 2014, 35:880-90. 10.1002\/humu.22565","journal-title":"Hum Mutat"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aef268","article-title":"Parkinson's disease and anaesthesia","volume":"89","author":"Nicholson G","year":"2002","unstructured":"Nicholson G, Pereira AC, Hall GM. Parkinson's disease and anaesthesia. Br J Anaesth. 2002, 89:904-16. 10.1093\/bja\/aef268","journal-title":"Br J Anaesth"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-198403000-00002","article-title":"Pharmacokinetics of levodopa","volume":"7","author":"Nutt JG","year":"1984","unstructured":"Nutt JG, Fellman JH. Pharmacokinetics of levodopa. Clin Neuropharmacol. 1984, 7:35-49. 10.1097\/00002826-198403000-00002","journal-title":"Clin Neuropharmacol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-024-06937-7","article-title":"Effect of crystalloid\u00a0solution co-loading infusion rate on the dose requirements of prophylactic phenylephrine for preventing hypotension following combined spinal-epidural anesthesia for cesarean delivery","volume":"24","author":"Zhang XM","year":"2024","unstructured":"Zhang XM, Qian J, Liu L, Shen YP, Xiao F. Effect of crystalloid\u00a0solution co-loading infusion rate on the dose requirements of prophylactic phenylephrine for preventing hypotension following combined spinal-epidural anesthesia for cesarean delivery. BMC Pregnancy Childbirth. 2024, 24:743. 10.1186\/s12884-024-06937-7","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200204000-00028","article-title":"A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery","volume":"94","author":"Lee A","year":"2002","unstructured":"Lee A, Ngan Kee WD, Gin T. A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg. 2002, 94:920-6, table of contents. 10.1097\/00000539-200204000-00028","journal-title":"Anesth Analg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000111","article-title":"Phenylephrine infusions for maintaining blood pressure during spinal anesthesia for cesarean delivery: finding the shoe that fits","volume":"118","author":"Ngan Kee WD","year":"2014","unstructured":"Ngan Kee WD. Phenylephrine infusions for maintaining blood pressure during spinal anesthesia for cesarean delivery: finding the shoe that fits. Anesth Analg. 2014, 118:496-8. 10.1213\/ANE.0000000000000111","journal-title":"Anesth Analg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.4103\/sja.SJA_809_19","article-title":"Anesthetic nuances in Segawa's syndrome: a case report and review of the literature","volume":"14","author":"Kaur M","year":"2020","unstructured":"Kaur M, Sharma U, Solanki RK. Anesthetic nuances in Segawa's syndrome: a case report and review of the literature. Saudi J Anaesth. 2020, 14:524-7. 10.4103\/sja.SJA_809_19","journal-title":"Saudi J Anaesth"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2008.00956.x","article-title":"Successful management of pregnancy in a patient with Segawa disease: case report and literature review","volume":"35","author":"Watanabe T","year":"2009","unstructured":"Watanabe T, Matsubara S, Baba Y, Tanaka H, Suzuki T, Suzuki M. Successful management of pregnancy in a patient with Segawa disease: case report and literature review. J Obstet Gynaecol Res. 2009, 35:562-4. 10.1111\/j.1447-0756.2008.00956.x","journal-title":"J Obstet Gynaecol Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2004.06.005","article-title":"Movement disorders in pregnancy","volume":"22","author":"Smith MS","year":"2004","unstructured":"Smith MS, Evatt ML. Movement disorders in pregnancy. Neurol Clin. 2004, 22:783-98. 10.1016\/j.ncl.2004.06.005","journal-title":"Neurol Clin"},{"key":"ref19","article-title":"British National Formulary","year":"2007","unstructured":"British National Formulary. BMJ Publishing Group, London; 2007."}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/484816-cesarean-delivery-in-a-patient-with-segawa-syndrome-dopamine-responsive-dystonia-under-epidural-anesthesia-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T08:25:48Z","timestamp":1776846348000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/484816-cesarean-delivery-in-a-patient-with-segawa-syndrome-dopamine-responsive-dystonia-under-epidural-anesthesia-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,22]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.107520","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,22]]}}}