{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T06:00:15Z","timestamp":1787032815383,"version":"build-2736575974"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,6]]},"DOI":"10.7759\/cureus.108398","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T05:23:33Z","timestamp":1778131413000},"source":"Crossref","is-referenced-by-count":1,"title":["Mammalian Diving Response in Humans: Inconsistently Beneficial for Survival"],"prefix":"10.7759","author":[{"given":"John","family":"Hayman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm","family":"Dodd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00515.2018","article-title":"The connection of life with respiration: Edmund Goodwyn\u2019s unexplored treasure of cardiopulmonary physiology","volume":"125","author":"Vega JL","year":"2018","unstructured":"Vega JL. The connection of life with respiration: Edmund Goodwyn\u2019s unexplored treasure of cardiopulmonary physiology. J Appl Physiol (1985). 2018, 125:1128-30. 10.1152\/japplphysiol.00515.2018","journal-title":"J Appl Physiol (1985)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00020.2013","article-title":"The mammalian diving response: an enigmatic reflex to preserve life?","volume":"28","author":"Panneton WM","year":"2013","unstructured":"Panneton WM. The mammalian diving response: an enigmatic reflex to preserve life?. Physiology (Bethesda). 2013, 28:284-97. 10.1152\/physiol.00020.2013","journal-title":"Physiology (Bethesda)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/0883073811415269","article-title":"The diving reflex in healthy infants in the first year of life","volume":"27","author":"Pedroso FS","year":"2012","unstructured":"Pedroso FS, Riesgo RS, Gatiboni T, Rotta NT. The diving reflex in healthy infants in the first year of life. J Child Neurol. 2012, 27:168-71. 10.1177\/0883073811415269","journal-title":"J Child Neurol"},{"key":"ref4","article-title":"Physiology, diving reflex","author":"Godek D","year":"2022","unstructured":"Godek D, Freeman AM. Physiology, diving reflex. StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL); 2022."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1988.tb08306.x","article-title":"The role of different facial areas in eliciting human diving bradycardia","volume":"132","author":"Schuitema K","year":"1988","unstructured":"Schuitema K, Holm B. The role of different facial areas in eliciting human diving bradycardia. Acta Physiol Scand. 1988, 132:119-20. 10.1111\/j.1748-1716.1988.tb08306.x","journal-title":"Acta Physiol Scand"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2021.w30039","article-title":"Heart rate profiles and heart rate variability during scuba diving","volume":"151","author":"Schaller C","year":"2021","unstructured":"Schaller C, F\u00fcmm A, Bachmann S, et al.. Heart rate profiles and heart rate variability during scuba diving. Swiss Med Wkly. 2021, 151:w30039. 10.4414\/smw.2021.w30039","journal-title":"Swiss Med Wkly"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/vetsci9080424","article-title":"Morphological structure of the aortic wall in deep diving cetacean species: evidence for diving adaptation","volume":"9","author":"Mompe\u00f3 B","year":"2022","unstructured":"Mompe\u00f3 B, Sacchini S, Quintana MD, Rivero M, Consoli F, Fern\u00e1ndez A, Bernaldo de Quir\u00f3s Y. Morphological structure of the aortic wall in deep diving cetacean species: evidence for diving adaptation. Vet Sci. 2022, 9:424. 10.3390\/vetsci9080424","journal-title":"Vet Sci"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.177212","article-title":"The caval sphincter in cetaceans and its predicted role in controlling venous flow during a dive","volume":"221","author":"Lillie MA","year":"2018","unstructured":"Lillie MA, Vogl AW, Raverty S, Haulena M, McLellan WA, Stenson GB, Shadwick RE. The caval sphincter in cetaceans and its predicted role in controlling venous flow during a dive. J Exp Biol. 2018, 221:jeb177212. 10.1242\/jeb.177212","journal-title":"J Exp Biol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1113\/JP271099","article-title":"The fetal brain sparing response to hypoxia: physiological mechanisms","volume":"594","author":"Giussani DA","year":"2016","unstructured":"Giussani DA. The fetal brain sparing response to hypoxia: physiological mechanisms. J Physiol. 2016, 594:1215-30. 10.1113\/JP271099","journal-title":"J Physiol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.00097","article-title":"Sudden unexpected death and the mammalian dive response: catastrophic failure of a complex tightly coupled system","volume":"10","author":"Vincenzi FF","year":"2019","unstructured":"Vincenzi FF. Sudden unexpected death and the mammalian dive response: catastrophic failure of a complex tightly coupled system. Front Physiol. 2019, 10:97. 10.3389\/fphys.2019.00097","journal-title":"Front Physiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.28920\/dhm54.3.188-195","article-title":"Arterial dissection in scuba divers: a potential adverse manifestation of the physiological effects of immersion","volume":"54","author":"Pollock NW","year":"2024","unstructured":"Pollock NW, Lippmann J, Pearn J, Hayman J. Arterial dissection in scuba divers: a potential adverse manifestation of the physiological effects of immersion. Diving Hyperb Med. 2024, 54:188-95. 10.28920\/dhm54.3.188-195","journal-title":"Diving Hyperb Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(89)91426-8","article-title":"Cold-induced pulmonary oedema in scuba divers and swimmers and subsequent development of hypertension","volume":"14","author":"Wilmshurst PT","year":"1989","unstructured":"Wilmshurst PT, Nuri M, Crowther A, Webb-Peploe MM. Cold-induced pulmonary oedema in scuba divers and swimmers and subsequent development of hypertension. Lancet. 1989, 14:62-5. 10.1016\/s0140-6736(89)91426-8","journal-title":"Lancet"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3109\/00313028609059488","article-title":"Fatal dissecting aneurysm of the aorta in a diver","volume":"18","author":"James R","year":"1986","unstructured":"James R, Hayman JA. Fatal dissecting aneurysm of the aorta in a diver. Pathology. 1986, 18:345-7. 10.3109\/00313028609059488","journal-title":"Pathology"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1113\/EP093047","article-title":"Carotid artery dissection linked to intermittent apnoeic swimming: a case-control study","volume":"26","author":"Bailey DM","year":"2025","unstructured":"Bailey DM, Davies RG, Gwilym BL, et al.. Carotid artery dissection linked to intermittent apnoeic swimming: a case-control study. Exp Physiol. 2025, 26:1-13. 10.1113\/EP093047","journal-title":"Exp Physiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccase.2010.08.001","article-title":"Aortic dissection and rupture in an 11-year-old child: a case report","volume":"3","author":"Eun LY","year":"2011","unstructured":"Eun LY, Cho DK, Cho YH, Byun KH. Aortic dissection and rupture in an 11-year-old child: a case report. J Cardiol Cases. 2011, 3:e46-9. 10.1016\/j.jccase.2010.08.001","journal-title":"J Cardiol Cases"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2009.202234","article-title":"Acute aortic dissection occurring during the butterfly stroke in a 12-year-old boy","volume":"9","author":"Uchida K","year":"2009","unstructured":"Uchida K, Imoto K, Yanagi H, Date K. Acute aortic dissection occurring during the butterfly stroke in a 12-year-old boy. Interact Cardiovasc Thorac Surg. 2009, 9:366-7. 10.1510\/icvts.2009.202234","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.28920\/dhm50.2.98-104","article-title":"Medical conditions in scuba diving fatality victims in Australia, 2001 to 2013","volume":"50","author":"Lippmann J","year":"2020","unstructured":"Lippmann J, Taylor DM. Medical conditions in scuba diving fatality victims in Australia, 2001 to 2013. Diving Hyperb Med. 2020, 50:98-104. 10.28920\/dhm50.2.98-104","journal-title":"Diving Hyperb Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2003.98.1.0180","article-title":"Barotrauma as a possible cause of aneurysmal subarachnoid hemorrhage. Case report","volume":"98","author":"Reichardt KA","year":"2003","unstructured":"Reichardt KA, Nabavi A, Barth H, Mehdorn HM, Bl\u00f6mer U. Barotrauma as a possible cause of aneurysmal subarachnoid hemorrhage. Case report. J Neurosurg. 2003, 98:180-2. 10.3171\/jns.2003.98.1.0180","journal-title":"J Neurosurg"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.06.030","article-title":"Nonaneurysmal subarachnoid hemorrhage in scuba diving","volume":"141","author":"Piper K","year":"2020","unstructured":"Piper K, Screven R, Agazzi S, Guerrero WR, Dombrowski K. Nonaneurysmal subarachnoid hemorrhage in scuba diving. World Neurosurg. 2020, 141:153-6. 10.1016\/j.wneu.2020.06.030","journal-title":"World Neurosurg"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1177\/1941874415573024","article-title":"Diving into the ice bucket challenge: intraparenchymal hemorrhage and the mammalian diving reflex","volume":"5","author":"McKee K","year":"2015","unstructured":"McKee K, Nelson S, Batra A, Klein JP, Henderson GV. Diving into the ice bucket challenge: intraparenchymal hemorrhage and the mammalian diving reflex. Neurohospitalist. 2015, 5:182-4. 10.1177\/1941874415573024","journal-title":"Neurohospitalist"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.855449","article-title":"Case report: a first case of spontaneous coronary artery dissection potentially associated with scuba diving","volume":"9","author":"Mahendiran T","year":"2022","unstructured":"Mahendiran T, Desgraz B, Antiochos P, Rubimbura V. Case report: a first case of spontaneous coronary artery dissection potentially associated with scuba diving. Front Cardiovasc Med. 2022, 9:855449. 10.3389\/fcvm.2022.855449","journal-title":"Front Cardiovasc Med"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0b013e328356a5f2","article-title":"Pathology of plaque haemorrhage and neovascularization of coronary artery","volume":"13","author":"Kodama T","year":"2012","unstructured":"Kodama T, Narula N, Agozzino M, Arbustini E. Pathology of plaque haemorrhage and neovascularization of coronary artery. J Cardiovasc Med (Hagerstown). 2012, 13:620-7. 10.2459\/JCM.0b013e328356a5f2","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1947.02890020007003","article-title":"Sustained hypertension; predisposing factors and causes of disability and death","volume":"135","author":"Levy RL","year":"1947","unstructured":"Levy RL, White PD, Stroud WD, Hillman CC. Sustained hypertension; predisposing factors and causes of disability and death. J Am Med Assoc. 1947, 135:77-80. 10.1001\/jama.1947.02890020007003","journal-title":"J Am Med Assoc"},{"key":"ref24","article-title":"Sudden infant death syndrome: an overview","author":"Duncan JR","year":"2018","unstructured":"Duncan JR, Byard RW.. Sudden infant death syndrome: an overview. SIDS Sudden Infant and Early Childhood Death: The Past, the Present and the Future. Duncan JR, Byard RW (ed): University of Adelaide Press, Adelaide; 2018."},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61662-6","article-title":"Sudden infant death syndrome","volume":"370","author":"Moon RY","year":"2007","unstructured":"Moon RY, Horne RSC, Hauck FR. Sudden infant death syndrome. Lancet. 2007, 370:1578-87. 10.1016\/S0140-6736(07)61662-6","journal-title":"Lancet"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2004.020867","article-title":"Sudden infant death triggered by dive reflex","volume":"58","author":"Matturri L","year":"2005","unstructured":"Matturri L, Ottaviani G, Lavezzi AM. Sudden infant death triggered by dive reflex. J Clin Pathol. 2005, 58:77-80. 10.1136\/jcp.2004.020867","journal-title":"J Clin Pathol"},{"key":"ref27","doi-asserted-by":"crossref","DOI":"10.1001\/jama.1995.03520340039033","article-title":"The contribution of changes in the prevalence of prone sleeping position to the decline in sudden infant death syndrome in Tasmania","volume":"273","author":"Dwyer T","year":"1995","unstructured":"Dwyer T, Ponsonby AL, Blizzard L, Newman NM, Cochrane JA. The contribution of changes in the prevalence of prone sleeping position to the decline in sudden infant death syndrome in Tasmania. JAMA. 1995, 273:783-789.","journal-title":"JAMA"},{"key":"ref28","article-title":"Pathological findings in SIDS","volume":"45","author":"Berry PJ","year":"1992","unstructured":"Berry PJ. Pathological findings in SIDS. J Clin Pathol. 1992, 45:11-6.","journal-title":"J Clin Pathol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/66.3.526","article-title":"Brain-stem and adrenal abnormalities in the sudden-infant-death syndrome","volume":"66","author":"Naeye RL","year":"1976","unstructured":"Naeye RL. Brain-stem and adrenal abnormalities in the sudden-infant-death syndrome. Am J Clin Pathol. 1976, 66:526-30. 10.1093\/ajcp\/66.3.526","journal-title":"Am J Clin Pathol"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00041.2010","article-title":"Hypoxic pulmonary vasoconstriction","volume":"92","author":"Sylvester JT","year":"2012","unstructured":"Sylvester JT, Shimoda LA, Aaronson PI, Ward JP. Hypoxic pulmonary vasoconstriction. Physiol Rev. 2012, 92:367-520. 10.1152\/physrev.00041.2010","journal-title":"Physiol Rev"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-014-0502-4","article-title":"Sudden unexpected death in epilepsy: addressing the challenges","volume":"14","author":"Smithson WH","year":"2014","unstructured":"Smithson WH, Colwell B, Hanna J. Sudden unexpected death in epilepsy: addressing the challenges. Curr Neurol Neurosci Rep. 2014, 14:502. 10.1007\/s11910-014-0502-4","journal-title":"Curr Neurol Neurosci Rep"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.1077624","article-title":"Analysis of forensic autopsy cases associated with epilepsy: comparison between sudden unexpected death in epilepsy (SUDEP) and not-SUDEP groups","volume":"13","author":"Zhang X","year":"2022","unstructured":"Zhang X, Zhang J, Wang J, Zou D, Li Z. Analysis of forensic autopsy cases associated with epilepsy: comparison between sudden unexpected death in epilepsy (SUDEP) and not-SUDEP groups. Front Neurol. 2022, 13:1077624. 10.3389\/fneur.2022.1077624","journal-title":"Front Neurol"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00677","article-title":"Ictal mammalian dive response: a likely cause of sudden unexpected death in epilepsy","volume":"9","author":"Vega JL","year":"2018","unstructured":"Vega JL. Ictal mammalian dive response: a likely cause of sudden unexpected death in epilepsy. Front Neurol. 2018, 9:677. 10.3389\/fneur.2018.00677","journal-title":"Front Neurol"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2024.10.005","article-title":"Sudden unexpected atraumatic arterial dissection-related death after seizures","volume":"123","author":"Vega JL","year":"2024","unstructured":"Vega JL, Karim N, Hall C. Sudden unexpected atraumatic arterial dissection-related death after seizures. Seizure. 2024, 123:43-8. 10.1016\/j.seizure.2024.10.005","journal-title":"Seizure"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00185","article-title":"Neuroimaging of sudden unexpected death in epilepsy (SUDEP): insights from structural and resting-state functional MRI studies","volume":"10","author":"Allen LA","year":"2019","unstructured":"Allen LA, Harper RM, Lhatoo S, Lemieux L, Diehl B. Neuroimaging of sudden unexpected death in epilepsy (SUDEP): insights from structural and resting-state functional MRI studies. Front Neurol. 2019, 10:185. 10.3389\/fneur.2019.00185","journal-title":"Front Neurol"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.28920\/dhm54.4.344-349","article-title":"Joint position statement on immersion pulmonary oedema and diving from the South Pacific Underwater Medicine Society (SPUMS) and the United Kingdom Diving Medical Committee (UKDMC) 2024","volume":"54","author":"Banham N","year":"2024","unstructured":"Banham N, Smart D, Wilmshurst P, Mitchell SJ, Turner MS, Bryson P. Joint position statement on immersion pulmonary oedema and diving from the South Pacific Underwater Medicine Society (SPUMS) and the United Kingdom Diving Medical Committee (UKDMC) 2024. Diving Hyperb Med. 2024, 54:344-9. 10.28920\/dhm54.4.344-349","journal-title":"Diving Hyperb Med"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/261404","article-title":"Immersion pulmonary edema in female triathletes","volume":"2011","author":"Carter EA","year":"2011","unstructured":"Carter EA, Koehle MS. Immersion pulmonary edema in female triathletes. Pulm Med. 2011, 2011:261404. 10.1155\/2011\/261404","journal-title":"Pulm Med"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.59392","article-title":"Swimming-induced pulmonary edema masquerading as acute respiratory distress syndrome: a case report","volume":"16","author":"Pokhrel M","year":"2024","unstructured":"Pokhrel M, Sharma NR, Lamichhane S, et al.. Swimming-induced pulmonary edema masquerading as acute respiratory distress syndrome: a case report. Cureus. 2024, 16:e59392. 10.7759\/cureus.59392","journal-title":"Cureus"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.019464","article-title":"Swimming-induced pulmonary edema: pathophysiology and risk reduction with sildenafil","volume":"133","author":"Moon RE","year":"2016","unstructured":"Moon RE, Martina SD, Peacher DF, et al.. Swimming-induced pulmonary edema: pathophysiology and risk reduction with sildenafil. Circulation. 2016, 133:988-96. 10.1161\/CIRCULATIONAHA.115.019464","journal-title":"Circulation"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/471315-mammalian-diving-response-in-humans-inconsistently-beneficial-for-survival","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T05:23:34Z","timestamp":1778131414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/471315-mammalian-diving-response-in-humans-inconsistently-beneficial-for-survival"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,6]]},"references-count":39,"URL":"https:\/\/doi.org\/10.7759\/cureus.108398","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,6]]}}}