{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T12:10:26Z","timestamp":1778242226663,"version":"3.51.4"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,8]]},"DOI":"10.7759\/cureus.108484","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T11:27:42Z","timestamp":1778239662000},"source":"Crossref","is-referenced-by-count":0,"title":["Improving Ventilator Care Quality Through a Structured Ventilator Pathway: A Retrospective Pre-Post Quality Improvement Study"],"prefix":"10.7759","author":[{"given":"Darshana","family":"Rathod","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kankana","family":"Samanta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piyali","family":"Chaudhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gauri","family":"Pathare","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shreyans","family":"Rai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayur","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"crossref","DOI":"10.3396\/ijic.v16i3.018.20","article-title":"Clinical usefulness of ventilator-associated events in predicting ventilator-associated pneumonia","volume":"16","author":"Havaldar AA","year":"2020","unstructured":"Havaldar AA, Rajgopalan N, Gupta V, Manjunath PH. Clinical usefulness of ventilator-associated events in predicting ventilator-associated pneumonia. Int J Infect Control. 2020, 16:","journal-title":"Int J Infect Control"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001871","article-title":"Incidence and characteristics of ventilator-associated events reported to the National Healthcare Safety Network in 2014","volume":"44","author":"Magill SS","year":"2016","unstructured":"Magill SS, Li Q, Gross C, Dudeck M, Allen-Bridson K, Edwards JR. Incidence and characteristics of ventilator-associated events reported to the National Healthcare Safety Network in 2014. Crit Care Med. 2016, 44:2154-62. 10.1097\/CCM.0000000000001871","journal-title":"Crit Care Med"},{"key":"ref3","article-title":"Assessing the efficacy of ventilator-associated event prevention bundle in the intensive care units: an intervention study","volume":"14","author":"Acun A","year":"2021","unstructured":"Acun A, Cali\u015fkan N. Assessing the efficacy of ventilator-associated event prevention bundle in the intensive care units: an intervention study. Int J Caring Sci. 2021, 14:1619.","journal-title":"Int J Caring Sci"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2018.10.54","article-title":"Ventilator-associated events versus ventilator-associated respiratory infections-moving into a new paradigm or merging both concepts, instead?","volume":"6","author":"Ramirez-Estrada S","year":"2018","unstructured":"Ramirez-Estrada S, Pe\u00f1a-Lopez Y, Kalwaje Eshwara V, Rello J. Ventilator-associated events versus ventilator-associated respiratory infections-moving into a new paradigm or merging both concepts, instead?. Ann Transl Med. 2018, 6:425. 10.21037\/atm.2018.10.54","journal-title":"Ann Transl Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2013893","article-title":"Developing a new, national approach to surveillance for ventilator-associated events","volume":"22","author":"Magill SS","year":"2013","unstructured":"Magill SS, Klompas M, Balk R, et al.. Developing a new, national approach to surveillance for ventilator-associated events. Am J Crit Care. 2013, 22:469-73. 10.4037\/ajcc2013893","journal-title":"Am J Crit Care"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics12010176","article-title":"Infection-related ventilator-associated complications in critically ill patients with trauma: a retrospective analysis","volume":"12","author":"Russo E","year":"2023","unstructured":"Russo E, Antonini MV, Sica A, et al.. Infection-related ventilator-associated complications in critically ill patients with trauma: a retrospective analysis. Antibiotics (Basel). 2023, 12:176. 10.3390\/antibiotics12010176","journal-title":"Antibiotics (Basel)"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics12020227","article-title":"The impact of care bundles on ventilator-associated pneumonia prevention in adult ICUs: a systematic review","volume":"12","author":"Mastrogianni M","year":"2023","unstructured":"Mastrogianni M, Katsoulas T, Galanis P, Korompeli A, Myrianthefs P. The impact of care bundles on ventilator-associated pneumonia prevention in adult ICUs: a systematic review. Antibiotics (Basel). 2023, 12:227. 10.3390\/antibiotics12020227","journal-title":"Antibiotics (Basel)"},{"key":"ref8","article-title":"Ventilator associated pneumonia (VAP): an impossible diagnosis? Call for a pragmatic approach","volume":"75","author":"Langer M","year":"2009","unstructured":"Langer M, Haeusler EA. Ventilator associated pneumonia (VAP): an impossible diagnosis? Call for a pragmatic approach. Minerva Anestesiol. 2009, 75:584-90.","journal-title":"Minerva Anestesiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1086\/677144","article-title":"Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update","volume":"35","author":"Klompas M","year":"2014","unstructured":"Klompas M, Branson R, Eichenwald EC, et al.. Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014, 35:915-36. 10.1086\/677144","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2013.09.007","article-title":"Efficacy of ventilator-associated pneumonia care bundle for prevention of ventilator-associated pneumonia in the surgical intensive care units of a medical center","volume":"48","author":"Lim KP","year":"2015","unstructured":"Lim KP, Kuo SW, Ko WJ, et al.. Efficacy of ventilator-associated pneumonia care bundle for prevention of ventilator-associated pneumonia in the surgical intensive care units of a medical center. J Microbiol Immunol Infect. 2015, 48:316-21. 10.1016\/j.jmii.2013.09.007","journal-title":"J Microbiol Immunol Infect"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-019-03596-x","article-title":"Factors associated with ventilator-associated events: an international multicenter prospective cohort study","volume":"38","author":"Rello J","year":"2019","unstructured":"Rello J, Ram\u00edrez-Estrada S, Romero A, et al.. Factors associated with ventilator-associated events: an international multicenter prospective cohort study. Eur J Clin Microbiol Infect Dis. 2019, 38:1693-9. 10.1007\/s10096-019-03596-x","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2004.5.237","article-title":"Is ventilator-associated pneumonia in trauma patients an epiphenomenon or a cause of death?","volume":"5","author":"Magnotti LJ","year":"2004","unstructured":"Magnotti LJ, Croce MA, Fabian TC. Is ventilator-associated pneumonia in trauma patients an epiphenomenon or a cause of death?. Surg Infect (Larchmt). 2004, 5:237-42. 10.1089\/sur.2004.5.237","journal-title":"Surg Infect (Larchmt)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-020-0624-6","article-title":"Accuracy of ventilator-associated events for the diagnosis of ventilator-associated lower respiratory tract infections","volume":"10","author":"Pouly O","year":"2020","unstructured":"Pouly O, Lecailtel S, Six S, Pr\u00e9au S, Wallet F, Nseir S, Rouz\u00e9 A. Accuracy of ventilator-associated events for the diagnosis of ventilator-associated lower respiratory tract infections. Ann Intensive Care. 2020, 10:6. 10.1186\/s13613-020-0624-6","journal-title":"Ann Intensive Care"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-93314-5","article-title":"The impact of infection complications after trauma differs according to trauma severity","volume":"11","author":"Komori A","year":"2021","unstructured":"Komori A, Iriyama H, Kainoh T, Aoki M, Naito T, Abe T. The impact of infection complications after trauma differs according to trauma severity. Sci Rep. 2021, 11:13803. 10.1038\/s41598-021-93314-5","journal-title":"Sci Rep"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70081-1","article-title":"Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies","volume":"13","author":"Melsen WG","year":"2013","unstructured":"Melsen WG, Rovers MM, Groenwold RHH, et al.. Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies. Lancet Infect Dis. 2013, 13:665-71. 10.1016\/S1473-3099(13)70081-1","journal-title":"Lancet Infect Dis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e3181c1c1bc","article-title":"Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia","volume":"67","author":"Cohen MJ","year":"2009","unstructured":"Cohen MJ, Bir N, Rahn P, et al.. Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia. J Trauma. 2009, 67:1176-81. 10.1097\/TA.0b013e3181c1c1bc","journal-title":"J Trauma"},{"key":"ref17","unstructured":"Centers for Disease Control and Prevention. National Healthcare Safety Network (NHSN) patient safety component manual. Ventilator-associated event (VAE) module. (2025). Accessed. n.d: https:\/\/www.cdc.gov\/nhsn\/pdfs\/pscmanual\/10-vae_final.pdf."},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198510000-00009","article-title":"APACHE II. A severity of disease classification system","volume":"13","author":"Knaus WA","year":"1985","unstructured":"Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II. A severity of disease classification system. Crit Care Med. 1985, 13:818-29. 10.1097\/00003246-198510000-00009","journal-title":"Crit Care Med"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.21.2703","article-title":"Delirium in mechanically ventilated patients. Validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU)","volume":"286","author":"Ely EW","year":"2001","unstructured":"Ely EW, Inouye SK, Bernard GR, et al.. Delirium in mechanically ventilated patients. Validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA. 2001, 286:2703-10. 10.1001\/jama.286.21.2703","journal-title":"JAMA"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2107138","article-title":"The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients","volume":"166","author":"Sessler CN","year":"2002","unstructured":"Sessler CN, Gosnell MS, Grap MJ, et al.. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002, 166:1338-44. 10.1164\/rccm.2107138","journal-title":"Am J Respir Crit Care Med"},{"key":"ref21","unstructured":"Agency for Healthcare Research and Quality. Coordinated spontaneous awakening and breathing trials (SAT\/SBT). AHRQ safety program for mechanically ventilated patients. (n.d). Accessed. n.d: https:\/\/www.ahrq.gov\/hai\/tools\/mvp\/modules\/technical\/sat-sbt-protocol.html."},{"key":"ref22","unstructured":"Centers for Disease Control and Prevention. National Healthcare Safety Network (NHSN). Ventilator-associated event (VAE) calculator. (n.d). Accessed. n.d: https:\/\/www.cdc.gov\/nhsn\/vae-calculator\/index.html."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2023.10.002","article-title":"Effects of ventilatory bundles on patient outcomes among ICU patients: a systematic review and meta-analysis","volume":"63","author":"Thapa D","year":"2024","unstructured":"Thapa D, Chair SY, Chong MS, Poudel RR, Melesse TG, Choi KC, Tam HL. Effects of ventilatory bundles on patient outcomes among ICU patients: a systematic review and meta-analysis. Heart Lung. 2024, 63:98-107. 10.1016\/j.hrtlng.2023.10.002","journal-title":"Heart Lung"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/s12912-022-00997-w","article-title":"Relationship between ventilator bundle compliance and the occurrence of ventilator-associated events: a prospective cohort study","volume":"21","author":"Hassan EA","year":"2022","unstructured":"Hassan EA, Elsaman SE. Relationship between ventilator bundle compliance and the occurrence of ventilator-associated events: a prospective cohort study. BMC Nurs. 2022, 21:207. 10.1186\/s12912-022-00997-w","journal-title":"BMC Nurs"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.07059","article-title":"Ventilator-associated events: what they are and what they are not","volume":"64","author":"Klompas M","year":"2019","unstructured":"Klompas M. Ventilator-associated events: what they are and what they are not. Respir Care. 2019, 64:953-61. 10.4187\/respcare.07059","journal-title":"Respir Care"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.62675\/2965-2774.20250128","article-title":"Protocolized strategies to encourage early mobilization of critical care patients: challenges and success","volume":"37","author":"Sep\u00falveda P","year":"2025","unstructured":"Sep\u00falveda P, Gallardo A, Arriagada R, Gonz\u00e1lez E, Rocco PR, Battaglini D. Protocolized strategies to encourage early mobilization of critical care patients: challenges and success. Crit Care Sci. 2025, 37:e20250128. 10.62675\/2965-2774.20250128","journal-title":"Crit Care Sci"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2018.05.50","article-title":"Effects of patient positioning on respiratory mechanics in mechanically ventilated ICU patients","volume":"6","author":"Mezidi M","year":"2018","unstructured":"Mezidi M, Gu\u00e9rin C. Effects of patient positioning on respiratory mechanics in mechanically ventilated ICU patients. Ann Transl Med. 2018, 6:384. 10.21037\/atm.2018.05.50","journal-title":"Ann Transl Med"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2019.08.031","article-title":"Communication with patients' families in the intensive care unit: a point prevalence study","volume":"54","author":"Au SS","year":"2019","unstructured":"Au SS, Roze des Ordons AL, Amir Ali A, Soo A, Stelfox HT. Communication with patients' families in the intensive care unit: a point prevalence study. J Crit Care. 2019, 54:235-8. 10.1016\/j.jcrc.2019.08.031","journal-title":"J Crit Care"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003173","article-title":"Rethinking ventilator bundles","volume":"46","author":"Klompas M","year":"2018","unstructured":"Klompas M, Kalil AC. Rethinking ventilator bundles. Crit Care Med. 2018, 46:1201-3. 10.1097\/CCM.0000000000003173","journal-title":"Crit Care Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/483890-improving-ventilator-care-quality-through-a-structured-ventilator-pathway-a-retrospective-pre-post-quality-improvement-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T11:27:45Z","timestamp":1778239665000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/483890-improving-ventilator-care-quality-through-a-structured-ventilator-pathway-a-retrospective-pre-post-quality-improvement-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,8]]},"references-count":29,"URL":"https:\/\/doi.org\/10.7759\/cureus.108484","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,8]]}}}