{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T16:09:55Z","timestamp":1778602195981,"version":"3.51.4"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,12]]},"DOI":"10.7759\/cureus.108725","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T15:24:03Z","timestamp":1778599443000},"source":"Crossref","is-referenced-by-count":0,"title":["Acanthamoeba Keratitis After Laser-Assisted In Situ Keratomileusis (LASIK) Successfully Treated With Polyhexamethylene Biguanide (PHMB) 0.08% Monotherapy: A Case Report"],"prefix":"10.7759","author":[{"given":"Diya","family":"Baker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanellina","family":"Kanellopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Kopsachilis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanxing","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_826_17","article-title":"Non-contact lens related Acanthamoeba keratitis","volume":"65","author":"Garg P","year":"2017","unstructured":"Garg P, Kalra P, Joseph J. Non-contact lens related Acanthamoeba keratitis. Indian J Ophthalmol. 2017, 65:1079-86. 10.4103\/ijo.IJO_826_17","journal-title":"Indian J Ophthalmol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.07.011","article-title":"Infectious keratitis in 204 586 LASIK procedures","volume":"117","author":"Llovet F","year":"2010","unstructured":"Llovet F, de Rojas V, Interlandi E, Mart\u00edn C, Cobo-Soriano R, Ortega-Usobiaga J, Baviera J. Infectious keratitis in 204 586 LASIK procedures. Ophthalmology. 2010, 117:232-8.e1-4. 10.1016\/j.ophtha.2009.07.011","journal-title":"Ophthalmology"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/03000605231206054","article-title":"Post-laser refractive surgery keratitis: a concise narrative review","volume":"51","author":"Soltani Shahgoli S","year":"2023","unstructured":"Soltani Shahgoli S, Cheraqpour K, Soleimani M, et al.. Post-laser refractive surgery keratitis: a concise narrative review. J Int Med Res. 2023, 51:3000605231206054. 10.1177\/03000605231206054","journal-title":"J Int Med Res"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-019-1165-3","article-title":"Corneal biomechanical properties after SMILE versus FLEX, LASIK, LASEK, or PRK: a systematic review and meta-analysis","volume":"19","author":"Guo H","year":"2019","unstructured":"Guo H, Hosseini-Moghaddam SM, Hodge W. Corneal biomechanical properties after SMILE versus FLEX, LASIK, LASEK, or PRK: a systematic review and meta-analysis. BMC Ophthalmol. 2019, 19:167. 10.1186\/s12886-019-1165-3","journal-title":"BMC Ophthalmol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177\/1120672120973606","article-title":"Topical corticosteroids in Acanthamoeba keratitis: friend or foe?","volume":"32","author":"Wouters KA","year":"2022","unstructured":"Wouters KA, Verhoekx JS, van Rooij J, Wubbels R, van Goor AT. Topical corticosteroids in Acanthamoeba keratitis: friend or foe?. Eur J Ophthalmol. 2022, 32:170-5. 10.1177\/1120672120973606","journal-title":"Eur J Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2023.09.031","article-title":"The Orphan Drug for Acanthamoeba Keratitis (ODAK) trial: PHMB 0.08% (polihexanide) and placebo versus PHMB 0.02% and propamidine 0.1","volume":"131","author":"Dart JK","year":"2024","unstructured":"Dart JK, Papa V, Rama P, et al.. The Orphan Drug for Acanthamoeba Keratitis (ODAK) trial: PHMB 0.08% (polihexanide) and placebo versus PHMB 0.02% and propamidine 0.1. Ophthalmology. 2024, 131:277-87. 10.1016\/j.ophtha.2023.09.031","journal-title":"Ophthalmology"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-023-02689-z","article-title":"Diagnostic accuracy of confocal scan in detecting acanthamoeba keratitis and fungal keratitis: a systematic review and meta-analysis","volume":"43","author":"Moshtaghion SM","year":"2023","unstructured":"Moshtaghion SM, Abolhosseini M, Yaseri M, Hosseini SB, Kanavi MR. Diagnostic accuracy of confocal scan in detecting acanthamoeba keratitis and fungal keratitis: a systematic review and meta-analysis. Int Ophthalmol. 2023, 43:3011-22. 10.1007\/s10792-023-02689-z","journal-title":"Int Ophthalmol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/11206721241299470","article-title":"Treatment of Acanthamoeba keratitis with high dose PHMB (0.08%) monotherapy in clinical practice: a case series","volume":"35","author":"Franch A","year":"2025","unstructured":"Franch A, Knutsson KA, Pedrotti E, et al.. Treatment of Acanthamoeba keratitis with high dose PHMB (0.08%) monotherapy in clinical practice: a case series. Eur J Ophthalmol. 2025, 35:1235-41. 10.1177\/11206721241299470","journal-title":"Eur J Ophthalmol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/life15060933","article-title":"Navigating the challenges of Acanthamoeba keratitis: current trends and future directions","volume":"15","author":"Fu L","year":"2025","unstructured":"Fu L, Wasielica-Poslednik J, Geerling G, et al.. Navigating the challenges of Acanthamoeba keratitis: current trends and future directions. Life (Basel). 2025, 15:933. 10.3390\/life15060933","journal-title":"Life (Basel)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2025.03.008","article-title":"Acanthamoeba keratitis treatment outcomes compared for drug delivery by protocol versus physician's individualised treatment","volume":"38","author":"Dart JK","year":"2025","unstructured":"Dart JK, Papa V, Rama P, et al.. Acanthamoeba keratitis treatment outcomes compared for drug delivery by protocol versus physician's individualised treatment. Ocul Surf. 2025, 38:132-41. 10.1016\/j.jtos.2025.03.008","journal-title":"Ocul Surf"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/471941-acanthamoeba-keratitis-after-laser-assisted-in-situ-keratomileusis-lasik-successfully-treated-with-polyhexamethylene-biguanide-phmb-008-monotherapy-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T15:24:04Z","timestamp":1778599444000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/471941-acanthamoeba-keratitis-after-laser-assisted-in-situ-keratomileusis-lasik-successfully-treated-with-polyhexamethylene-biguanide-phmb-008-monotherapy-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,12]]},"references-count":10,"URL":"https:\/\/doi.org\/10.7759\/cureus.108725","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,12]]}}}