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(Article in Spanish)","volume":"3","author":"S\u00e1nchez-Duque JA","year":"2025","unstructured":"S\u00e1nchez-Duque JA, Manrique-Hern\u00e1ndez E, Pantoja-Molina AD, Morales-Ceballos LX, Manrique-Hern\u00e1ndez KT, Acosta-Quevedo EA. Approach to opioid-induced constipation in cancer patients: a narrative review. (Article in Spanish). Rev Col Cancerol. 2025, 3:89-102. 10.35509\/01239015.1116","journal-title":"Rev Col Cancerol"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1310455","article-title":"The preventive effects of ondansetron on chemotherapy-induced nausea and vomiting in adult cancer patients: systematic review from ClinicalTrials.gov","volume":"14","author":"Ashour AM","year":"2023","unstructured":"Ashour AM. The preventive effects of ondansetron on chemotherapy-induced nausea and vomiting in adult cancer patients: systematic review from ClinicalTrials.gov. 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Oncologist. 2019, 24:e347-57. 10.1634\/theoncologist.2018-0140","journal-title":"Oncologist"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2021.05.017","article-title":"Mirtazapine in cancer-associated anorexia and cachexia: a double-blind placebo-controlled randomized trial","volume":"62","author":"Hunter CN","year":"2021","unstructured":"Hunter CN, Abdel-Aal HH, Elsherief WA, Farag DE, Riad NM, Alsirafy SA. Mirtazapine in cancer-associated anorexia and cachexia: a double-blind placebo-controlled randomized trial. J Pain Symptom Manage. 2021, 62:1207-15. 10.1016\/j.jpainsymman.2021.05.017","journal-title":"J Pain Symptom Manage"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.2007.01778.x","article-title":"Effectiveness of mirtazapine for nausea and insomnia in cancer patients with depression","volume":"62","author":"Kim SW","year":"2008","unstructured":"Kim SW, Shin IS, Kim JM, et al.. Effectiveness of mirtazapine for nausea and insomnia in cancer patients with depression. Psychiatry Clin Neurosci. 2008, 62:75-83. 10.1111\/j.1440-1819.2007.01778.x","journal-title":"Psychiatry Clin Neurosci"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012555.pub2","article-title":"Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults","volume":"9","author":"Sutherland A","year":"2018","unstructured":"Sutherland A, Naessens K, Plugge E, Ware L, Head K, Burton MJ, Wee B. Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults. Cochrane Database Syst Rev. 2018, 9:CD012555. 10.1002\/14651858.CD012555.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.83118","article-title":"Olanzapine versus aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis","volume":"17","author":"Sarma I","year":"2025","unstructured":"Sarma I, Buragohain S, Lahon J, et al.. Olanzapine versus aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis. Cureus. 2025, 17:e83118. 10.7759\/cureus.83118","journal-title":"Cureus"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdl347","article-title":"Antiemetic activity of corticosteroids in patients receiving cancer chemotherapy: dosing, efficacy, and tolerability analysis","volume":"18","author":"Grunberg SM","year":"2007","unstructured":"Grunberg SM. 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