{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T03:08:47Z","timestamp":1779160127950,"version":"3.51.4"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,18]]},"DOI":"10.7759\/cureus.109148","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T02:47:21Z","timestamp":1779158841000},"source":"Crossref","is-referenced-by-count":0,"title":["Factor XIII Supplementation Suppresses Recurrent Hemorrhages Due to Acquired Factor XIII Deficiency Secondary to Severe Acute Pancreatitis: A Case Report"],"prefix":"10.7759","author":[{"given":"Tatsuya","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidenobu","family":"Ochiai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-019-0158-2","article-title":"New insights into acute pancreatitis","volume":"16","author":"Lee PJ","year":"2019","unstructured":"Lee PJ, Papachristou GI. New insights into acute pancreatitis. Nat Rev Gastroenterol Hepatol. 2019, 16:479-96. 10.1038\/s41575-019-0158-2","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12774","article-title":"Long-term mortality in acute pancreatitis-a population-based cohort study","volume":"13","author":"Selin D","year":"2025","unstructured":"Selin D, Maret-Ouda J, Oskarsson V, et al.. Long-term mortality in acute pancreatitis-a population-based cohort study. United European Gastroenterol J. 2025, 13:640-9. 10.1002\/ueg2.12774","journal-title":"United European Gastroenterol J"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.14701\/ahbps.2020.24.3.292","article-title":"Hemorrhage complicating the course of severe acute pancreatitis","volume":"24","author":"Gupta V","year":"2020","unstructured":"Gupta V, Krishna P, Kochhar R, et al.. Hemorrhage complicating the course of severe acute pancreatitis. Ann Hepatobiliary Pancreat Surg. 2020, 24:292-300. 10.14701\/ahbps.2020.24.3.292","journal-title":"Ann Hepatobiliary Pancreat Surg"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1160\/TH14-07-0625","article-title":"Coagulation factor XIII: a multifunctional transglutaminase with clinical potential in a range of conditions","volume":"113","author":"Dickneite G","year":"2015","unstructured":"Dickneite G, Herwald H, Korte W, Allanore Y, Denton CP, Matucci Cerinic M. Coagulation factor XIII: a multifunctional transglutaminase with clinical potential in a range of conditions. Thromb Haemost. 2015, 113:686-97. 10.1160\/TH14-07-0625","journal-title":"Thromb Haemost"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2018.10.013","article-title":"Acquired factor XIII deficiency: a review","volume":"57","author":"Yan MT","year":"2018","unstructured":"Yan MT, Rydz N, Goodyear D, Sholzberg M. Acquired factor XIII deficiency: a review. Transfus Apher Sci. 2018, 57:724-30. 10.1016\/j.transci.2018.10.013","journal-title":"Transfus Apher Sci"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18020354","article-title":"The interplay between inflammation, coagulation and endothelial injury in the early phase of acute pancreatitis: clinical implications","volume":"18","author":"Dumnicka P","year":"2017","unstructured":"Dumnicka P, Maduzia D, Ceranowicz P, Olszanecki R, Dro\u017cd\u017c R, Ku\u015bnierz-Cabala B. The interplay between inflammation, coagulation and endothelial injury in the early phase of acute pancreatitis: clinical implications. Int J Mol Sci. 2017, 18:10.3390\/ijms18020354","journal-title":"Int J Mol Sci"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-03940-2","article-title":"The impact of acquired coagulation factor XIII deficiency in traumatic bleeding and wound healing","volume":"26","author":"Kleber C","year":"2022","unstructured":"Kleber C, Sablotzki A, Casu S, et al.. The impact of acquired coagulation factor XIII deficiency in traumatic bleeding and wound healing. Crit Care. 2022, 26:69. 10.1186\/s13054-022-03940-2","journal-title":"Crit Care"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-018-1736-4","article-title":"Effect of early administration of coagulation factor XIII on fistula after pancreatic surgery: the FIPS randomized controlled trial","volume":"403","author":"Takeda Y","year":"2018","unstructured":"Takeda Y, Mise Y, Ishizuka N, et al.. Effect of early administration of coagulation factor XIII on fistula after pancreatic surgery: the FIPS randomized controlled trial. Langenbecks Arch Surg. 2018, 403:933-40. 10.1007\/s00423-018-1736-4","journal-title":"Langenbecks Arch Surg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjan.2017.11.004","article-title":"Factor XIII-guided treatment algorithm reduces blood transfusion in burn surgery (Article in Portuguese)","volume":"68","author":"Carneiro JM","year":"2018","unstructured":"Carneiro JM, Alves J, Conde P, et al.. Factor XIII-guided treatment algorithm reduces blood transfusion in burn surgery (Article in Portuguese). Braz J Anesthesiol. 2018, 68:238-43. 10.1016\/j.bjan.2017.11.004","journal-title":"Braz J Anesthesiol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/488914-factor-xiii-supplementation-suppresses-recurrent-hemorrhages-due-to-acquired-factor-xiii-deficiency-secondary-to-severe-acute-pancreatitis-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T02:47:22Z","timestamp":1779158842000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/488914-factor-xiii-supplementation-suppresses-recurrent-hemorrhages-due-to-acquired-factor-xiii-deficiency-secondary-to-severe-acute-pancreatitis-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,18]]},"references-count":9,"URL":"https:\/\/doi.org\/10.7759\/cureus.109148","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,18]]}}}