{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:08:22Z","timestamp":1779361702806,"version":"3.51.4"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,21]]},"DOI":"10.7759\/cureus.109338","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:52:19Z","timestamp":1779360739000},"source":"Crossref","is-referenced-by-count":0,"title":["When Time Precludes Certainty: Intravenous Tenecteplase for Acute Global Aphasia in a Young Woman Along With Post-acute Diagnostic Reorientation"],"prefix":"10.7759","author":[{"given":"Adniel","family":"Garc\u00eda Cruz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jhonatan A","family":"Rojas Cristancho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gretel","family":"Pimentel Barreiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia M","family":"Ramirez Mendez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alena","family":"Arbos Aguilar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000402","article-title":"Identifying best practices to improve evaluation and management of in-hospital stroke: a scientific statement from the American Heart Association","volume":"53","author":"Nouh A","year":"2022","unstructured":"Nouh A, Amin-Hanjani S, Furie KL, et al.. Identifying best practices to improve evaluation and management of in-hospital stroke: a scientific statement from the American Heart Association. Stroke. 2022, 53:e165-75. 10.1161\/STR.0000000000000402","journal-title":"Stroke"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12227067","article-title":"Frequency and characteristics of non-neurological and neurological stroke mimics in the emergency department","volume":"12","author":"K\u00fchne Escol\u00e0 J","year":"2023","unstructured":"K\u00fchne Escol\u00e0 J, Bozkurt B, Brune B, et al.. Frequency and characteristics of non-neurological and neurological stroke mimics in the emergency department. J Clin Med. 2023, 12:7067. 10.3390\/jcm12227067","journal-title":"J Clin Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A7379","article-title":"Stroke mimics in the acute setting: role of multimodal CT protocol","volume":"43","author":"Prodi E","year":"2022","unstructured":"Prodi E, Danieli L, Manno C, et al.. Stroke mimics in the acute setting: role of multimodal CT protocol. AJNR Am J Neuroradiol. 2022, 43:216-22. 10.3174\/ajnr.A7379","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.5811\/westjem.39718","article-title":"The incidence of stroke mimics in the emergency department of a tertiary-care center in Lebanon","volume":"26","author":"Anan H","year":"2025","unstructured":"Anan H, Bizri M, Jomaa M, Ibrahim N, Mufarrij A. The incidence of stroke mimics in the emergency department of a tertiary-care center in Lebanon. West J Emerg Med. 2025, 26:943-50. 10.5811\/westjem.39718","journal-title":"West J Emerg Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2021.09.025","article-title":"Ischemic stroke mimics: a comprehensive review","volume":"93","author":"Pohl M","year":"2021","unstructured":"Pohl M, Hesszenberger D, Kapus K, et al.. Ischemic stroke mimics: a comprehensive review. J Clin Neurosci. 2021, 93:174-82. 10.1016\/j.jocn.2021.09.025","journal-title":"J Clin Neurosci"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30201-1","article-title":"Sex differences in the evaluation and treatment of acute ischaemic stroke","volume":"17","author":"Bushnell C","year":"2018","unstructured":"Bushnell C, Howard VJ, Lisabeth L, et al.. Sex differences in the evaluation and treatment of acute ischaemic stroke. Lancet Neurol. 2018, 17:641-50. 10.1016\/S1474-4422(18)30201-1","journal-title":"Lancet Neurol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.028821","article-title":"Value of vascular and non-vascular pattern on computed tomography perfusion in patients with acute isolated aphasia","volume":"51","author":"Rudilosso S","year":"2020","unstructured":"Rudilosso S, Rodr\u00edguez A, Amaro S, et al.. Value of vascular and non-vascular pattern on computed tomography perfusion in patients with acute isolated aphasia. Stroke. 2020, 51:2480-7. 10.1161\/STROKEAHA.120.028821","journal-title":"Stroke"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2017.10.013","article-title":"Isolated aphasia in the emergency department: the likelihood of ischemia is low","volume":"163","author":"Casella G","year":"2017","unstructured":"Casella G, Llinas RH, Marsh EB. Isolated aphasia in the emergency department: the likelihood of ischemia is low. Clin Neurol Neurosurg. 2017, 163:24-6. 10.1016\/j.clineuro.2017.10.013","journal-title":"Clin Neurol Neurosurg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.009012","article-title":"Safety of intravenous thrombolysis in stroke mimics: prospective 5-year study and comprehensive meta-analysis","volume":"46","author":"Tsivgoulis G","year":"2015","unstructured":"Tsivgoulis G, Zand R, Katsanos AH, et al.. Safety of intravenous thrombolysis in stroke mimics: prospective 5-year study and comprehensive meta-analysis. Stroke. 2015, 46:1281-7. 10.1161\/STROKEAHA.115.009012","journal-title":"Stroke"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/ene.13944","article-title":"Intravenous thrombolysis in stroke mimics: results from the SITS International Stroke Thrombolysis Register","volume":"26","author":"Keselman B","year":"2019","unstructured":"Keselman B, Cooray C, Vanhooren G, et al.. Intravenous thrombolysis in stroke mimics: results from the SITS International Stroke Thrombolysis Register. Eur J Neurol. 2019, 26:1091-7. 10.1111\/ene.13944","journal-title":"Eur J Neurol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/phar.70112","article-title":"Safety of tenecteplase in stroke mimics compared with acute ischemic stroke: a retrospective cohort study","volume":"46","author":"Rowe AS","year":"2026","unstructured":"Rowe AS, Wiseman B, Hamilton LA, Crowell S, McCampbell L, Ford D. Safety of tenecteplase in stroke mimics compared with acute ischemic stroke: a retrospective cohort study. Pharmacotherapy. 2026, 46:e70112. 10.1002\/phar.70112","journal-title":"Pharmacotherapy"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.19.5.604","article-title":"Interobserver agreement for the assessment of handicap in stroke patients","volume":"19","author":"van Swieten JC","year":"1988","unstructured":"van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJ, van Gijn J. Interobserver agreement for the assessment of handicap in stroke patients. Stroke. 1988, 19:604-7. 10.1161\/01.str.19.5.604","journal-title":"Stroke"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.20.7.864","article-title":"Measurements of acute cerebral infarction: a clinical examination scale","volume":"20","author":"Brott T","year":"1989","unstructured":"Brott T, Adams HP Jr, Olinger CP, et al.. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989, 20:864-70. 10.1161\/01.str.20.7.864","journal-title":"Stroke"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2013.08.003","article-title":"The CARE guidelines: consensus-based clinical case report guideline development","volume":"67","author":"Gagnier JJ","year":"2014","unstructured":"Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D. The CARE guidelines: consensus-based clinical case report guideline development. J Clin Epidemiol. 2014, 67:46-51. 10.1016\/j.jclinepi.2013.08.003","journal-title":"J Clin Epidemiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000513","article-title":"2026 guideline for the early management of patients with acute ischemic stroke: a guideline from the American Heart Association\/American Stroke Association","author":"Prabhakaran S","year":"2026","unstructured":"Prabhakaran S, Gonzalez NR, Zachrison KS, et al.. 2026 guideline for the early management of patients with acute ischemic stroke: a guideline from the American Heart Association\/American Stroke Association. Stroke. 2026, 10.1161\/STR.0000000000000513","journal-title":"Stroke"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/490344-when-time-precludes-certainty-intravenous-tenecteplase-for-acute-global-aphasia-in-a-young-woman-along-with-post-acute-diagnostic-reorientation","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:52:19Z","timestamp":1779360739000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/490344-when-time-precludes-certainty-intravenous-tenecteplase-for-acute-global-aphasia-in-a-young-woman-along-with-post-acute-diagnostic-reorientation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,21]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.109338","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,21]]}}}