{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T17:09:47Z","timestamp":1779469787658,"version":"3.53.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,22]]},"DOI":"10.7759\/cureus.109440","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T16:38:57Z","timestamp":1779467937000},"source":"Crossref","is-referenced-by-count":0,"title":["Type 1 Diabetes Mellitus in a Child With Genetically Confirmed Alstr\u00f6m Syndrome: An Unusual Autoimmune Phenotype"],"prefix":"10.7759","author":[{"given":"Ali S","family":"Alquraishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada","family":"Al Alammar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musa M","family":"Saad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruba A","family":"Alqahtani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2174\/138920211795677912","article-title":"Alstr\u00f6m syndrome: genetics and clinical overview","volume":"12","author":"Marshall JD","year":"2011","unstructured":"Marshall JD, Maffei P, Collin GB, Naggert JK. Alstr\u00f6m syndrome: genetics and clinical overview. Curr Genomics. 2011, 12:225-35. 10.2174\/138920211795677912","journal-title":"Curr Genomics"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-49","article-title":"Alstrom syndrome (OMIM 203800): a case report and literature review","volume":"2","author":"Joy T","year":"2007","unstructured":"Joy T, Cao H, Black G, Malik R, Charlton-Menys V, Hegele RA, Durrington PN. Alstrom syndrome (OMIM 203800): a case report and literature review. Orphanet J Rare Dis. 2007, 2:49. 10.1186\/1750-1172-2-49","journal-title":"Orphanet J Rare Dis"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-2633","article-title":"Syndromic obesity and diabetes: changes in body composition with age and mutation analysis of ALMS1 in 12 United Kingdom kindreds with Alstrom syndrome","volume":"91","author":"Minton JA","year":"2006","unstructured":"Minton JA, Owen KR, Ricketts CJ, et al.. Syndromic obesity and diabetes: changes in body composition with age and mutation analysis of ALMS1 in 12 United Kingdom kindreds with Alstrom syndrome. J Clin Endocrinol Metab. 2006, 91:3110-6. 10.1210\/jc.2005-2633","journal-title":"J Clin Endocrinol Metab"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006192","article-title":"Alstr\u00f6m syndrome: a novel mutation in Saudi girl with insulin-resistant diabetes","volume":"96","author":"Bakar AA","year":"2017","unstructured":"Bakar AA, Kamal NM, Alsaedi A, Turkistani R, Aldosari D. Alstr\u00f6m syndrome: a novel mutation in Saudi girl with insulin-resistant diabetes. Medicine (Baltimore). 2017, 96:e6192. 10.1097\/MD.0000000000006192","journal-title":"Medicine (Baltimore)"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.15406\/MOJCR.2017.06.00168","article-title":"Inappropriate treatment of diabetes in an adult patient with alstr\u00f6m syndrome: effect of adding metformin","volume":"6","author":"Ucan B","year":"2017","unstructured":"Ucan B, Kizilgul M, Erten R, et al.. Inappropriate treatment of diabetes in an adult patient with alstr\u00f6m syndrome: effect of adding metformin. MOJ Clin Med Case Rep. 2017, 6:90-2. 10.15406\/MOJCR.2017.06.00168","journal-title":"MOJ Clin Med Case Rep"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1210\/jcemcr\/luac012","article-title":"Alstr\u00f6m syndrome: a rare cause of severe insulin resistance","volume":"1","author":"Radi S","year":"2023","unstructured":"Radi S, Binmahfooz S, Nawar S, Malaikah H. Alstr\u00f6m syndrome: a rare cause of severe insulin resistance. JCEM Case Rep. 2023, 1:luac012. 10.1210\/jcemcr\/luac012","journal-title":"JCEM Case Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8227(02)00004-9","article-title":"Evaluation of insulin resistant diabetes mellitus in Alstr\u00f6m syndrome: a long-term prospective follow-up of three siblings","volume":"56","author":"Satman I","year":"2002","unstructured":"Satman I, Yilmaz MT, G\u00fcrsoy N, et al.. Evaluation of insulin resistant diabetes mellitus in Alstr\u00f6m syndrome: a long-term prospective follow-up of three siblings. Diabetes Res Clin Pract. 2002, 56:189-96. 10.1016\/S0168-8227(02)00004-9","journal-title":"Diabetes Res Clin Pract"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.18502\/crcp.v9i6.18944","article-title":"A rare syndromic report of a young patient with type 2 diabetes mellitus: Alstrom syndrome","volume":"9","author":"Suran A","year":"2025","unstructured":"Suran A, Khare J. A rare syndromic report of a young patient with type 2 diabetes mellitus: Alstrom syndrome. Case Rep Clin Pract. 2025, 9:10.18502\/crcp.v9i6.18944","journal-title":"Case Rep Clin Pract"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2011.00789.x","article-title":"The progression from obesity to type 2 diabetes in Alstr\u00f6m syndrome","volume":"13","author":"Bettini V","year":"2012","unstructured":"Bettini V, Maffei P, Pagano C, et al.. The progression from obesity to type 2 diabetes in Alstr\u00f6m syndrome. Pediatr Diabetes. 2012, 13:59-67. 10.1111\/j.1399-5448.2011.00789.x","journal-title":"Pediatr Diabetes"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-S317","article-title":"Beta-cell protection and therapy for latent autoimmune diabetes in adults","volume":"32 Suppl 2","author":"Cernea S","year":"2009","unstructured":"Cernea S, Buzzetti R, Pozzilli P. Beta-cell protection and therapy for latent autoimmune diabetes in adults. Diabetes Care. 2009, 32 Suppl 2:S246-52. 10.2337\/dc09-S317","journal-title":"Diabetes Care"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1530\/EDM-21-0212","article-title":"The coexistence of autoimmune diabetes and maturity-onset diabetes of the young (MODY): a case series","volume":"2022","author":"O'Donovan EM","year":"2022","unstructured":"O'Donovan EM, Sanchez-Lechuga B, Prehn E, Byrne MM. The coexistence of autoimmune diabetes and maturity-onset diabetes of the young (MODY): a case series. Endocrinol Diabetes Metab Case Rep. 2022, 2022:10.1530\/EDM-21-0212","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgad277","article-title":"Autoimmune diabetes from childhood to adulthood: the role of pancreatic autoantibodies and HLA-DRB1 genotype","volume":"108","author":"Urrutia I","year":"2023","unstructured":"Urrutia I, Mart\u00ednez R, Calvo B, et al.. Autoimmune diabetes from childhood to adulthood: the role of pancreatic autoantibodies and HLA-DRB1 genotype. J Clin Endocrinol Metab. 2023, 108:e1341-6. 10.1210\/clinem\/dgad277","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/496181-type-1-diabetes-mellitus-in-a-child-with-genetically-confirmed-alstrm-syndrome-an-unusual-autoimmune-phenotype","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T16:38:58Z","timestamp":1779467938000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/496181-type-1-diabetes-mellitus-in-a-child-with-genetically-confirmed-alstrm-syndrome-an-unusual-autoimmune-phenotype"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.109440","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,22]]}}}