{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T17:05:55Z","timestamp":1779901555510,"version":"3.53.1"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,27]]},"DOI":"10.7759\/cureus.109751","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:43:47Z","timestamp":1779900227000},"source":"Crossref","is-referenced-by-count":0,"title":["Computed Tomography-Guided and Magnetic Resonance-Guided Adaptive Radiotherapy for Gynecological Stereotactic Body Radiotherapy Treatments: A Dosimetry and Workflow Analysis"],"prefix":"10.7759","author":[{"given":"Dishane C","family":"Luximon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rojine T","family":"Ariani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Charters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan","family":"O'Connell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puja","family":"Venkat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-018-0310-8","article-title":"Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: improving patient selection for adjuvant therapy","volume":"119","author":"Wortman BG","year":"2018","unstructured":"Wortman BG, Creutzberg CL, Putter H, et al.. Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: improving patient selection for adjuvant therapy. Br J Cancer. 2018, 119:1067-74. 10.1038\/s41416-018-0310-8","journal-title":"Br J Cancer"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2020-001199","article-title":"External beam radiotherapy versus vaginal brachytherapy in patients with stage II endometrial cancer: a systematic review and meta-analysis","volume":"30","author":"Narasimhulu DM","year":"2020","unstructured":"Narasimhulu DM, Cope A, Riaz IB, et al.. External beam radiotherapy versus vaginal brachytherapy in patients with stage II endometrial cancer: a systematic review and meta-analysis. Int J Gynecol Cancer. 2020, 30:797-805. 10.1136\/ijgc-2020-001199","journal-title":"Int J Gynecol Cancer"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1136357","article-title":"Expanding radiotherapy access in Sub-Saharan Africa: an analysis of travel burdens and patient-related benefits of hypofractionation","volume":"13","author":"Patel S","year":"2023","unstructured":"Patel S, Olatunji E, Mallum A, et al.. Expanding radiotherapy access in Sub-Saharan Africa: an analysis of travel burdens and patient-related benefits of hypofractionation. Front Oncol. 2023, 13:1136357. 10.3389\/fonc.2023.1136357","journal-title":"Front Oncol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13112802","article-title":"Interfractional geometric variations and dosimetric benefits of stereotactic MRI guided online adaptive radiotherapy (SMART) of prostate bed after radical prostatectomy: post-hoc analysis of a phase II trial","volume":"13","author":"Cao M","year":"2021","unstructured":"Cao M, Gao Y, Yoon SM, et al.. Interfractional geometric variations and dosimetric benefits of stereotactic MRI guided online adaptive radiotherapy (SMART) of prostate bed after radical prostatectomy: post-hoc analysis of a phase II trial. Cancers (Basel). 2021, 13:2802. 10.3390\/cancers13112802","journal-title":"Cancers (Basel)"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2017.07.028","article-title":"Fast and robust online adaptive planning in stereotactic MR-guided adaptive radiation therapy (SMART) for pancreatic cancer","volume":"125","author":"Bohoudi O","year":"2017","unstructured":"Bohoudi O, Bruynzeel AM, Senan S, Cuijpers JP, Slotman BJ, Lagerwaard FJ, Palacios MA. Fast and robust online adaptive planning in stereotactic MR-guided adaptive radiation therapy (SMART) for pancreatic cancer. Radiother Oncol. 2017, 125:439-44. 10.1016\/j.radonc.2017.07.028","journal-title":"Radiother Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2017.11.032","article-title":"Phase I trial of stereotactic MR-guided online adaptive radiation therapy (SMART) for the treatment of oligometastatic or unresectable primary malignancies of the abdomen","volume":"126","author":"Henke L","year":"2018","unstructured":"Henke L, Kashani R, Robinson C, et al.. Phase I trial of stereotactic MR-guided online adaptive radiation therapy (SMART) for the treatment of oligometastatic or unresectable primary malignancies of the abdomen. Radiother Oncol. 2018, 126:519-26. 10.1016\/j.radonc.2017.11.032","journal-title":"Radiother Oncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2024.07.014","article-title":"Moderated hypofractionated online adaptive radiotherapy in locally advanced cervical cancer: a prospective 1 clinical trial","volume":"120","author":"Zeng Z","year":"2024","unstructured":"Zeng Z, Zhang F, Yan J. Moderated hypofractionated online adaptive radiotherapy in locally advanced cervical cancer: a prospective 1 clinical trial. Int J Radiat Oncol Biol Phys. 2024, 120:S17-8. 10.1016\/j.ijrobp.2024.07.014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/cancers18071112","article-title":"Preliminary results regarding the feasibility and outcomes of MR-Linac adaptive stereotactic body radiotherapy combined with systemic treatment among patients with pelvic-abdominal recurrent or metastatic gynecological malignancies: a single-institution experience","volume":"18","author":"Yang X","year":"2026","unstructured":"Yang X, Zhao S, Liu Z, et al.. Preliminary results regarding the feasibility and outcomes of MR-Linac adaptive stereotactic body radiotherapy combined with systemic treatment among patients with pelvic-abdominal recurrent or metastatic gynecological malignancies: a single-institution experience. Cancers (Basel). 2026, 18:1112. 10.3390\/cancers18071112","journal-title":"Cancers (Basel)"},{"key":"ref9","unstructured":"ClinicalTrials.gov. Hypofractionated external beam radiotherapy with adaptive planning for endometrial and cervical cancers (HERA). (2025). https.\/\/clinicaltrials.gov\/study\/NCT06538337."},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14923","article-title":"FIGO staging of endometrial cancer: 2023","volume":"162","author":"Berek JS","year":"2023","unstructured":"Berek JS, Matias-Guiu X, Creutzberg C, et al.. FIGO staging of endometrial cancer: 2023. Int J Gynaecol Obstet. 2023, 162:383-94. 10.1002\/ijgo.14923","journal-title":"Int J Gynaecol Obstet"},{"key":"ref11","article-title":"The clinical evaluation of chemotherapeutic agents in cancer","author":"Karnofsky DA","year":"1949","unstructured":"Karnofsky DA, Burchenal JH. The clinical evaluation of chemotherapeutic agents in cancer. Evaluation of Chemotherapeutic Agents. MacLeod CM (ed): Columbia University Press, New York, NY; 1949. 191-205."},{"key":"ref12","article-title":"Toxicity and response criteria of the Eastern Cooperative Oncology Group","volume":"5","author":"Oken MM","year":"1982","unstructured":"Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982, 5:649-56.","journal-title":"Am J Clin Oncol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.13539","article-title":"Assessment of efficacy in automated plan generation for Varian Ethos intelligent optimization engine","volume":"23","author":"Pokharel S","year":"2022","unstructured":"Pokharel S, Pacheco A, Tanner S. Assessment of efficacy in automated plan generation for Varian Ethos intelligent optimization engine. J Appl Clin Med Phys. 2022, 23:e13539. 10.1002\/acm2.13539","journal-title":"J Appl Clin Med Phys"},{"key":"ref14","article-title":"Making on-line adaptive radiotherapy possible using artificial intelligence and machine learning for efficient daily re-planning","volume":"8","author":"Archambault Y","year":"2020","unstructured":"Archambault Y, Boylan C, Bullock D, et al.. Making on-line adaptive radiotherapy possible using artificial intelligence and machine learning for efficient daily re-planning. Med Phys Int J. 2020, 8:77-82.","journal-title":"Med Phys Int J"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.12551","article-title":"Geometric and dosimetric impact of anatomical changes for MR-only radiation therapy for the prostate","volume":"20","author":"Nejad-Davarani SP","year":"2019","unstructured":"Nejad-Davarani SP, Sevak P, Moncion M, et al.. Geometric and dosimetric impact of anatomical changes for MR-only radiation therapy for the prostate. J Appl Clin Med Phys. 2019, 20:10-7. 10.1002\/acm2.12551","journal-title":"J Appl Clin Med Phys"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2023.12.035","article-title":"Quantifying intrafraction motion and the impact of gating for magnetic resonance imaging-guided stereotactic radiation therapy for prostate cancer: analysis of the magnetic resonance imaging arm from the MIRAGE phase 3 randomized trial","volume":"118","author":"Neylon J","year":"2024","unstructured":"Neylon J, Ma TM, Savjani R, et al.. Quantifying intrafraction motion and the impact of gating for magnetic resonance imaging-guided stereotactic radiation therapy for prostate cancer: analysis of the magnetic resonance imaging arm from the MIRAGE phase 3 randomized trial. Int J Radiat Oncol Biol Phys. 2024, 118:1181-91. 10.1016\/j.ijrobp.2023.12.035","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctro.2023.100661","article-title":"Initial clinical experience building a dual CT- and MR-guided adaptive radiotherapy program","volume":"42","author":"Price AT","year":"2023","unstructured":"Price AT, Schiff JP, Laugeman E, et al.. Initial clinical experience building a dual CT- and MR-guided adaptive radiotherapy program. Clin Transl Radiat Oncol. 2023, 42:100661. 10.1016\/j.ctro.2023.100661","journal-title":"Clin Transl Radiat Oncol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/490988-computed-tomography-guided-and-magnetic-resonance-guided-adaptive-radiotherapy-for-gynecological-stereotactic-body-radiotherapy-treatments-a-dosimetry-and-workflow-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:43:48Z","timestamp":1779900228000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/490988-computed-tomography-guided-and-magnetic-resonance-guided-adaptive-radiotherapy-for-gynecological-stereotactic-body-radiotherapy-treatments-a-dosimetry-and-workflow-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,27]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.109751","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,27]]}}}