{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T18:15:15Z","timestamp":1780510515903,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,3]]},"DOI":"10.7759\/cureus.110186","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:41:43Z","timestamp":1780508503000},"source":"Crossref","is-referenced-by-count":0,"title":["Orbital Myeloid Sarcoma Masquerading as Orbital Cellulitis: A Diagnostic Challenge in an Adult Patient"],"prefix":"10.7759","author":[{"given":"Rahisha","family":"Maskey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharan","family":"Thapa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver W","family":"Spencer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Avila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-03-209262","article-title":"The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes","volume":"114","author":"Vardiman JW","year":"2009","unstructured":"Vardiman JW, Thiele J, Arber DA, et al.. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009, 114:937-51. 10.1182\/blood-2009-03-209262","journal-title":"Blood"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2017.02.027","article-title":"Myeloid sarcoma: presentation, diagnosis, and treatment","volume":"17","author":"Almond LM","year":"2017","unstructured":"Almond LM, Charalampakis M, Ford SJ, Gourevitch D, Desai A. Myeloid sarcoma: presentation, diagnosis, and treatment. Clin Lymphoma Myeloma Leuk. 2017, 17:263-7. 10.1016\/j.clml.2017.02.027","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2013.06.004","article-title":"Orbital extra-medullary granulocytic sarcoma: clinicopathologic correlation with immunohistochemical features","volume":"59","author":"Aggarwal E","year":"2014","unstructured":"Aggarwal E, Mulay K, Honavar SG. Orbital extra-medullary granulocytic sarcoma: clinicopathologic correlation with immunohistochemical features. Surv Ophthalmol. 2014, 59:232-5. 10.1016\/j.survophthal.2013.06.004","journal-title":"Surv Ophthalmol"},{"key":"ref4","article-title":"Acute myeloid leukemia presenting with sudden bilateral proptosis as a sole manifestation","volume":"38","author":"Swami G","year":"2001","unstructured":"Swami G, Arya A, Chowdhry B. Acute myeloid leukemia presenting with sudden bilateral proptosis as a sole manifestation. Indian Pediatr. 2001, 38:1199-200.","journal-title":"Indian Pediatr"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(75)90326-8","article-title":"Ophthalmologic manifestations of granulocytic sarcoma (myeloid sarcoma or chloroma)","volume":"80","author":"Zimmerman LE","year":"1975","unstructured":"Zimmerman LE, Font RL. Ophthalmologic manifestations of granulocytic sarcoma (myeloid sarcoma or chloroma). Am J Ophthalmol. 1975, 80:975-90. 10.1016\/0002-9394(75)90326-8","journal-title":"Am J Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/1756-8722-2-4","article-title":"Extramedullary leukemia in children presenting with proptosis","volume":"2","author":"Murthy R","year":"2009","unstructured":"Murthy R, Vemuganti GK, Honavar SG, Naik M, Reddy V. Extramedullary leukemia in children presenting with proptosis. J Hematol Oncol. 2009, 2:4. 10.1186\/1756-8722-2-4","journal-title":"J Hematol Oncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/395196","article-title":"Myeloid sarcoma: a rare case of an orbital mass mimicking orbital pseudotumor requiring neurosurgical intervention","volume":"2014","author":"Payne C","year":"2014","unstructured":"Payne C, Olivero WC, Wang B, Moon SJ, Farahvar A, Chen E, Wang H. Myeloid sarcoma: a rare case of an orbital mass mimicking orbital pseudotumor requiring neurosurgical intervention. Case Rep Neurol Med. 2014, 2014:395196. 10.1155\/2014\/395196","journal-title":"Case Rep Neurol Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199310000-00006","article-title":"Extramedullary myeloid cell tumors. An immunohistochemical and morphologic study of 28 cases","volume":"17","author":"Traweek ST","year":"1993","unstructured":"Traweek ST, Arber DA, Rappaport H, Brynes RK. Extramedullary myeloid cell tumors. An immunohistochemical and morphologic study of 28 cases. Am J Surg Pathol. 1993, 17:1011-9. 10.1097\/00000478-199310000-00006","journal-title":"Am J Surg Pathol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10399","article-title":"Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature","volume":"94","author":"Yamauchi K","year":"2002","unstructured":"Yamauchi K, Yasuda M. Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer. 2002, 94:1739-46. 10.1002\/cncr.10399","journal-title":"Cancer"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810915)48:6<1426::aid-cncr2820480626>3.0.co;2-g","article-title":"Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases","volume":"48","author":"Neiman RS","year":"1981","unstructured":"Neiman RS, Barcos M, Berard C, et al.. Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer. 1981, 48:1426-37. 10.1002\/1097-0142(19810915)48:6&lt;1426::aid-cncr2820480626&gt;3.0.co;2-g","journal-title":"Cancer"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx484","article-title":"Improved survival using specialized multidisciplinary board in sarcoma patients","volume":"28","author":"Blay JY","year":"2017","unstructured":"Blay JY, Soibinet P, Penel N, et al.. Improved survival using specialized multidisciplinary board in sarcoma patients. Ann Oncol. 2017, 28:2852-9. 10.1093\/annonc\/mdx484","journal-title":"Ann Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3390\/cimb47020111","article-title":"Diagnostic approaches in myeloid sarcoma","volume":"47","author":"Patkowska E","year":"2025","unstructured":"Patkowska E, Krzywdzinska A, Solarska I, Wojtas M, Prochorec-Sobieszek M. Diagnostic approaches in myeloid sarcoma. Curr Issues Mol Biol. 2025, 47:111. 10.3390\/cimb47020111","journal-title":"Curr Issues Mol Biol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2017.0116","article-title":"Acute myeloid leukemia, version 3.2017, NCCN clinical practice guidelines in oncology","volume":"15","author":"O'Donnell MR","year":"2017","unstructured":"O'Donnell MR, Tallman MS, Abboud CN, et al.. Acute myeloid leukemia, version 3.2017, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2017, 15:926-57. 10.6004\/jnccn.2017.0116","journal-title":"J Natl Compr Canc Netw"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159\/000253592","article-title":"Prognostic factors of treatment outcomes in patients with granulocytic sarcoma","volume":"122","author":"Lan TY","year":"2009","unstructured":"Lan TY, Lin DT, Tien HF, Yang RS, Chen CY, Wu K. Prognostic factors of treatment outcomes in patients with granulocytic sarcoma. Acta Haematol. 2009, 122:238-46. 10.1159\/000253592","journal-title":"Acta Haematol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13206154","article-title":"Myeloid sarcoma: novel advances regarding molecular pathogenesis, presentation and therapeutic options","volume":"13","author":"Diamantidis MD","year":"2024","unstructured":"Diamantidis MD. Myeloid sarcoma: novel advances regarding molecular pathogenesis, presentation and therapeutic options. J Clin Med. 2024, 13:6154. 10.3390\/jcm13206154","journal-title":"J Clin Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-023-05288-1","article-title":"Myeloid sarcoma: more and less than a distinct entity","volume":"102","author":"Loscocco GG","year":"2023","unstructured":"Loscocco GG, Vannucchi AM. Myeloid sarcoma: more and less than a distinct entity. Ann Hematol. 2023, 102:1973-84. 10.1007\/s00277-023-05288-1","journal-title":"Ann Hematol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2021.01.004","article-title":"Treatment outcomes of intracranial myeloid sarcomas: a meta-analysis","volume":"148","author":"Lee D","year":"2021","unstructured":"Lee D, Omofoye OA, Nu\u00f1o MA, Riestenberg RA, Shahlaie K. Treatment outcomes of intracranial myeloid sarcomas: a meta-analysis. World Neurosurg. 2021, 148:29-37. 10.1016\/j.wneu.2021.01.004","journal-title":"World Neurosurg"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23691","article-title":"Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia","volume":"113","author":"Tsimberidou AM","year":"2008","unstructured":"Tsimberidou AM, Kantarjian HM, Wen S, et al.. Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia. Cancer. 2008, 113:1370-8. 10.1002\/cncr.23691","journal-title":"Cancer"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergencyto.2008.04.016","article-title":"Preceding orbital granulocytic sarcoma in an adult patient with acute myelogenous leukemia with t(8;21): a case study and review of the literature","volume":"185","author":"Lee SG","year":"2008","unstructured":"Lee SG, Park TS, Cheong JW, et al.. Preceding orbital granulocytic sarcoma in an adult patient with acute myelogenous leukemia with t(8;21): a case study and review of the literature. Cancer Genet Cytogenet. 2008, 185:51-4. 10.1016\/j.cancergencyto.2008.04.016","journal-title":"Cancer Genet Cytogenet"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3389\/pore.2024.1611818","article-title":"Orbital myeloid sarcoma: a report of two rare cases and review of the literature","volume":"30","author":"Li Y","year":"2024","unstructured":"Li Y, Wang Y, He W. Orbital myeloid sarcoma: a report of two rare cases and review of the literature. Pathol Oncol Res. 2024, 30:1611818. 10.3389\/pore.2024.1611818","journal-title":"Pathol Oncol Res"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/490487-orbital-myeloid-sarcoma-masquerading-as-orbital-cellulitis-a-diagnostic-challenge-in-an-adult-patient","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:41:44Z","timestamp":1780508504000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/490487-orbital-myeloid-sarcoma-masquerading-as-orbital-cellulitis-a-diagnostic-challenge-in-an-adult-patient"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,3]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.110186","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,3]]}}}