{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T10:30:34Z","timestamp":1785148234094,"version":"3.55.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,7]]},"DOI":"10.7759\/cureus.110413","type":"journal-article","created":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T18:38:30Z","timestamp":1780857510000},"source":"Crossref","is-referenced-by-count":1,"title":["Heparin-Induced Anaphylaxis With Cardiac Arrest in a Patient With Alpha-Gal Syndrome: A Case Report"],"prefix":"10.7759","author":[{"given":"Ramtin","family":"Khanipour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reetom K","family":"Bera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idelisse","family":"Suarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arman","family":"Soltani Moghadam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jishanth","family":"Mattumpuram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3389\/falgy.2021.783279","article-title":"The \u03b1-gal syndrome and potential mechanisms","volume":"2","author":"Rom\u00e1n-Carrasco P","year":"2021","unstructured":"Rom\u00e1n-Carrasco P, Hemmer W, Cabezas-Cruz A, Hod\u017ei\u0107 A, de la Fuente J, Swoboda I. The \u03b1-gal syndrome and potential mechanisms. Front Allergy. 2021, 2:783279. 10.3389\/falgy.2021.783279","journal-title":"Front Allergy"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/s0300-9084(01)01294-9","article-title":"The \u03b1-Gal epitope (Gal\u03b11-3Gal\u03b21-4GlcNAc-R) in xenotransplantation","volume":"83","author":"Galili U","year":"2001","unstructured":"Galili U. The \u03b1-Gal epitope (Gal\u03b11-3Gal\u03b21-4GlcNAc-R) in xenotransplantation. Biochimie. 2001, 83:557-63. 10.1016\/s0300-9084(01)01294-9","journal-title":"Biochimie"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7230a2","article-title":"Geographic Distribution of suspected alpha-gal syndrome cases - United States, January 2017-December 2022","volume":"72","author":"Thompson JM","year":"2023","unstructured":"Thompson JM, Carpenter A, Kersh GJ, Wachs T, Commins SP, Salzer JS. Geographic Distribution of suspected alpha-gal syndrome cases - United States, January 2017-December 2022. MMWR Morb Mortal Wkly Rep. 2023, 72:815-20. 10.15585\/mmwr.mm7230a2","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s40629-016-0099-z","article-title":"Clinical spectrum of \u03b1-Gal syndrome: from immediate-type to delayed immediate-type reactions to mammalian innards and meat","volume":"25","author":"Fischer J","year":"2016","unstructured":"Fischer J, Yazdi AS, Biedermann T. Clinical spectrum of \u03b1-Gal syndrome: from immediate-type to delayed immediate-type reactions to mammalian innards and meat. Allergo J Int. 2016, 25:55-62. 10.1007\/s40629-016-0099-z","journal-title":"Allergo J Int"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2024.06.044","article-title":"Clinical presentation and outcomes of alpha-gal syndrome","volume":"23","author":"Lesmana E","year":"2025","unstructured":"Lesmana E, Rao S, Keehn A, Edwinson AL, Makol A, Grover M. Clinical presentation and outcomes of alpha-gal syndrome. Clin Gastroenterol Hepatol. 2025, 23:69-78. 10.1016\/j.cgh.2024.06.044","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.12890\/2023_003939","article-title":"Alpha-gal syndrome - a case report of tick-borne anaphylactic shock","volume":"10","author":"M\u00fcller J","year":"2023","unstructured":"M\u00fcller J, Radej J, Kriz M, Hunkova E, Kasparek J, Matejovic M. Alpha-gal syndrome - a case report of tick-borne anaphylactic shock. Eur J Case Rep Intern Med. 2023, 10:003939. 10.12890\/2023_003939","journal-title":"Eur J Case Rep Intern Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2020.07.050","article-title":"Safety of intravenous heparin for cardiac surgery in patients with alpha-gal syndrome","volume":"111","author":"Hawkins RB","year":"2021","unstructured":"Hawkins RB, Wilson JM, Mehaffey JH, Platts-Mills TA, Ailawadi G. Safety of intravenous heparin for cardiac surgery in patients with alpha-gal syndrome. Ann Thorac Surg. 2021, 111:1991-7. 10.1016\/j.athoracsur.2020.07.050","journal-title":"Ann Thorac Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2016-0010","article-title":"Kounis syndrome: an update on epidemiology, pathogenesis, diagnosis and therapeutic management","volume":"54","author":"Kounis NG","year":"2016","unstructured":"Kounis NG. Kounis syndrome: an update on epidemiology, pathogenesis, diagnosis and therapeutic management. Clin Chem Lab Med. 2016, 54:1545-59. 10.1515\/cclm-2016-0010","journal-title":"Clin Chem Lab Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2025-326599","article-title":"Allergic vasospastic angina: a systematic review [Online ahead of print]","author":"Quetsch M","year":"2025","unstructured":"Quetsch M, Kette F, Tavella R, Beltrame J. Allergic vasospastic angina: a systematic review [Online ahead of print]. Heart. 2025, 10.1136\/heartjnl-2025-326599","journal-title":"Heart"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2011.00225","article-title":"Arrhythmogenic effect of sympathetic histamine in mouse hearts subjected to acute ischemia","volume":"18","author":"He G","year":"2012","unstructured":"He G, Hu J, Li T, et al.. Arrhythmogenic effect of sympathetic histamine in mouse hearts subjected to acute ischemia. Mol Med. 2012, 18:1-9. 10.2119\/molmed.2011.00225","journal-title":"Mol Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2021.101869","article-title":"A retrospective evaluation of heparin product reactions in patients with alpha-gal allergies","volume":"13","author":"Nwamara U","year":"2022","unstructured":"Nwamara U, Kaplan MC, Mason N, Ingemi AI. A retrospective evaluation of heparin product reactions in patients with alpha-gal allergies. Ticks Tick Borne Dis. 2022, 13:101869. 10.1016\/j.ttbdis.2021.101869","journal-title":"Ticks Tick Borne Dis"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.26857","article-title":"Management of food allergies and food-related anaphylaxis","volume":"331","author":"Iglesia EG","year":"2024","unstructured":"Iglesia EG, Kwan M, Virkud YV, Iweala OI. Management of food allergies and food-related anaphylaxis. JAMA. 2024, 331:510-21. 10.1001\/jama.2023.26857","journal-title":"JAMA"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2020.1782745","article-title":"Diagnosis &amp; management of alpha-gal syndrome: lessons from 2,500 patients","volume":"16","author":"Commins SP","year":"2020","unstructured":"Commins SP. Diagnosis &amp;amp; management of alpha-gal syndrome: lessons from 2,500 patients. Expert Rev Clin Immunol. 2020, 16:667-77. 10.1080\/1744666X.2020.1782745","journal-title":"Expert Rev Clin Immunol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2023.08.491","article-title":"Alpha-gal syndrome: a novel and increasingly common cause of anaphylaxis","volume":"83","author":"Edlow JA","year":"2024","unstructured":"Edlow JA. Alpha-gal syndrome: a novel and increasingly common cause of anaphylaxis. Ann Emerg Med. 2024, 83:380-4. 10.1016\/j.annemergmed.2023.08.491","journal-title":"Ann Emerg Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/424887-heparin-induced-anaphylaxis-with-cardiac-arrest-in-a-patient-with-alpha-gal-syndrome-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T18:38:31Z","timestamp":1780857511000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/424887-heparin-induced-anaphylaxis-with-cardiac-arrest-in-a-patient-with-alpha-gal-syndrome-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,7]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.110413","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,7]]}}}