{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T17:55:51Z","timestamp":1781805351260,"version":"3.54.5"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,18]]},"DOI":"10.7759\/cureus.111100","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T17:27:23Z","timestamp":1781803643000},"source":"Crossref","is-referenced-by-count":0,"title":["Simultaneous High-Grade Upper-Tract Urothelial Carcinoma and Xanthogranulomatous Pyelonephritis"],"prefix":"10.7759","author":[{"given":"Sohail","family":"Nakhuda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adedeji","family":"Fatuga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laxmi","family":"Radhakrishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ata","family":"Jaffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000282924","article-title":"Xanthogranulomatous pyelonephritis associated with transitional cell carcinoma of the renal pelvis","volume":"57","author":"Val-Bernal JF","year":"1996","unstructured":"Val-Bernal JF, Castro F. Xanthogranulomatous pyelonephritis associated with transitional cell carcinoma of the renal pelvis. Urol Int. 1996, 57:240-5. 10.1159\/000282924","journal-title":"Urol Int"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2016.11.018","article-title":"High-grade transitional cell carcinoma masquerading as a xanthogranulomatous pyelonephritis and perinephric abscess","volume":"12","author":"Ordones FV","year":"2017","unstructured":"Ordones FV, Das K, Prowse S, Cohen P, Brook NR. High-grade transitional cell carcinoma masquerading as a xanthogranulomatous pyelonephritis and perinephric abscess. Radiol Case Rep. 2017, 12:281-4. 10.1016\/j.radcr.2016.11.018","journal-title":"Radiol Case Rep"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/6021178","article-title":"Concurrent xanthogranulomatous pyelonephritis and upper urinary tract transitional cell carcinoma","volume":"2023","author":"Guglin A","year":"2023","unstructured":"Guglin A, Weiss R, Singh A, Mittal A, Hwang T, Shah A. Concurrent xanthogranulomatous pyelonephritis and upper urinary tract transitional cell carcinoma. Case Rep Urol. 2023, 2023:6021178. 10.1155\/2023\/6021178","journal-title":"Case Rep Urol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2019.11.22","article-title":"Epidemiology, clinical presentation, and evaluation of upper-tract urothelial carcinoma","volume":"9","author":"Petros FG","year":"2020","unstructured":"Petros FG. Epidemiology, clinical presentation, and evaluation of upper-tract urothelial carcinoma. Transl Androl Urol. 2020, 9:1794-8. 10.21037\/tau.2019.11.22","journal-title":"Transl Androl Urol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.09292sc","article-title":"Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells","volume":"112","author":"Nishioku T","year":"2010","unstructured":"Nishioku T, Matsumoto J, Dohgu S, et al.. Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells. J Pharmacol Sci. 2010, 112:251-4. 10.1254\/jphs.09292sc","journal-title":"J Pharmacol Sci"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.21967","article-title":"Xanthogranulomatous pyelonephritis presenting as a psoas abscess","volume":"14","author":"Mendon\u00e7a C","year":"2022","unstructured":"Mendon\u00e7a C, Freitas S, Jesus S. Xanthogranulomatous pyelonephritis presenting as a psoas abscess. Cureus. 2022, 14:e21967. 10.7759\/cureus.21967","journal-title":"Cureus"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-021-00800-z","article-title":"Xanthogranulomatous pyelonephritis: a focus on microbiological and antibiotic resistance profiles","volume":"21","author":"Artiles-Medina A","year":"2021","unstructured":"Artiles-Medina A, Laso-Garc\u00eda I, Lorca-\u00c1lvaro J, et al.. Xanthogranulomatous pyelonephritis: a focus on microbiological and antibiotic resistance profiles. BMC Urol. 2021, 21:56. 10.1186\/s12894-021-00800-z","journal-title":"BMC Urol"},{"key":"ref8","unstructured":"Medscape. Xanthogranulomatous pyelonephritis. (2024). Accessed. November 2025: https:\/\/emedicine.medscape.com\/article\/2050430-overview#?form=fpf.."},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(85)90197-9","article-title":"Simultaneous occurrence of transitional cell carcinoma and urothelial adenocarcinoma associated with xanthogranulomatous pyelonephritis","volume":"26","author":"Godec CJ","year":"1985","unstructured":"Godec CJ, Murrah VA. Simultaneous occurrence of transitional cell carcinoma and urothelial adenocarcinoma associated with xanthogranulomatous pyelonephritis. Urology. 1985, 26:412-5. 10.1016\/0090-4295(85)90197-9","journal-title":"Urology"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-13-310","article-title":"Risk of bladder cancer in patients with diabetes mellitus: an updated meta-analysis of 36 observational studies","volume":"13","author":"Zhu Z","year":"2013","unstructured":"Zhu Z, Wang X, Shen Z, Lu Y, Zhong S, Xu C. Risk of bladder cancer in patients with diabetes mellitus: an updated meta-analysis of 36 observational studies. BMC Cancer. 2013, 13:310. 10.1186\/1471-2407-13-310","journal-title":"BMC Cancer"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-020-00632-3","article-title":"Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review","volume":"20","author":"Ding X","year":"2020","unstructured":"Ding X, Wang G, Wang T, Ma X, Wang Y. Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review. BMC Urol. 2020, 20:63. 10.1186\/s12894-020-00632-3","journal-title":"BMC Urol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4103\/iju.IJU_173_20","article-title":"Upper tract transitional cell carcinoma clinically mimicking inflammatory renal pathology: a report of three cases","volume":"37","author":"Jena R","year":"2021","unstructured":"Jena R, Sureka SK, Singh UP. Upper tract transitional cell carcinoma clinically mimicking inflammatory renal pathology: a report of three cases. Indian J Urol. 2021, 37:169-72. 10.4103\/iju.IJU_173_20","journal-title":"Indian J Urol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/467076-simultaneous-high-grade-upper-tract-urothelial-carcinoma-and-xanthogranulomatous-pyelonephritis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T17:27:24Z","timestamp":1781803644000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/467076-simultaneous-high-grade-upper-tract-urothelial-carcinoma-and-xanthogranulomatous-pyelonephritis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,18]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.111100","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,18]]}}}