{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T15:51:34Z","timestamp":1781970694570,"version":"3.54.5"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,20]]},"DOI":"10.7759\/cureus.111198","type":"journal-article","created":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T15:21:12Z","timestamp":1781968872000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes of Robotic Stereotactic Accelerated Partial Breast Irradiation: A Structured Literature Review"],"prefix":"10.7759","author":[{"given":"Yuri A","family":"Gerasimov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina V","family":"Mazurok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin","family":"Nikitin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentin A","family":"Vaskovskii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia Y","family":"Germanovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anatoliy Y","family":"Popov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.00650","article-title":"Accelerated partial-breast irradiation compared with whole-breast irradiation for early breast cancer: long-term results of the randomized phase III APBI-IMRT-Florence trial","volume":"38","author":"Meattini I","year":"2020","unstructured":"Meattini I, Marrazzo L, Saieva C, et al.. Accelerated partial-breast irradiation compared with whole-breast irradiation for early breast cancer: long-term results of the randomized phase III APBI-IMRT-Florence trial. J Clin Oncol. 2020, 38:4175-83. 10.1200\/JCO.20.00650","journal-title":"J Clin Oncol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32515-2","article-title":"External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial","volume":"394","author":"Whelan TJ","year":"2019","unstructured":"Whelan TJ, Julian JA, Berrang TS, et al.. External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial. Lancet. 2019, 394:2165-72. 10.1016\/S0140-6736(19)32515-2","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31145-5","article-title":"Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial","volume":"390","author":"Coles CE","year":"2017","unstructured":"Coles CE, Griffin CL, Kirby AM, et al.. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet. 2017, 390:1048-60. 10.1016\/S0140-6736(17)31145-5","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.00451","article-title":"Partial breast irradiation versus whole breast irradiation for early breast cancer patients in a randomized phase III trial: the Danish breast cancer group partial breast irradiation trial","volume":"40","author":"Offersen BV","year":"2022","unstructured":"Offersen BV, Alsner J, Nielsen HM, et al.. Partial breast irradiation versus whole breast irradiation for early breast cancer patients in a randomized phase III trial: the Danish breast cancer group partial breast irradiation trial. J Clin Oncol. 2022, 40:4189-97. 10.1200\/JCO.22.00451","journal-title":"J Clin Oncol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2023.11.001","article-title":"Partial breast irradiation for patients with early-stage invasive breast cancer or ductal carcinoma in situ: an ASTRO clinical practice guideline","volume":"14","author":"Shaitelman SF","year":"2024","unstructured":"Shaitelman SF, Anderson BM, Arthur DW, et al.. Partial breast irradiation for patients with early-stage invasive breast cancer or ductal carcinoma in situ: an ASTRO clinical practice guideline. Pract Radiat Oncol. 2024, 14:112-32. 10.1016\/j.prro.2023.11.001","journal-title":"Pract Radiat Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.tipsro.2023.100219","article-title":"ESTRO-ACROP guideline for positioning, immobilisation and setup verification for local and loco-regional photon breast cancer irradiation","volume":"28","author":"Mast ME","year":"2023","unstructured":"Mast ME, Leong A, Korreman SS, Lee G, Probst H, Scherer P, Tsang Y. ESTRO-ACROP guideline for positioning, immobilisation and setup verification for local and loco-regional photon breast cancer irradiation. Tech Innov Patient Support Radiat Oncol. 2023, 28:100219. 10.1016\/j.tipsro.2023.100219","journal-title":"Tech Innov Patient Support Radiat Oncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2024.0035","article-title":"Breast cancer, version 3.2024, NCCN clinical practice guidelines in oncology","volume":"22","author":"Gradishar WJ","year":"2024","unstructured":"Gradishar WJ, Moran MS, Abraham J, et al.. Breast cancer, version 3.2024, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2024, 22:331-57. 10.6004\/jnccn.2024.0035","journal-title":"J Natl Compr Canc Netw"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2218-676X.2014.07.06","article-title":"CyberKnife stereotactic body radiotherapy and CyberKnife accelerated partial breast irradiation for the treatment of early breast cancer","volume":"3","author":"Vermeulen SS","year":"2014","unstructured":"Vermeulen SS, Haas JA. CyberKnife stereotactic body radiotherapy and CyberKnife accelerated partial breast irradiation for the treatment of early breast cancer. Transl Cancer Res. 2014, 3:295-302. 10.3978\/j.issn.2218-676X.2014.07.06","journal-title":"Transl Cancer Res"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2016.00129","article-title":"Stereotactic accelerated partial breast irradiation for early-stage breast cancer: rationale, feasibility, and early experience using the CyberKnife radiosurgery delivery platform","volume":"6","author":"Obayomi-Davies O","year":"2016","unstructured":"Obayomi-Davies O, Kole TP, Oppong B, et al.. Stereotactic accelerated partial breast irradiation for early-stage breast cancer: rationale, feasibility, and early experience using the CyberKnife radiosurgery delivery platform. Front Oncol. 2016, 6:129. 10.3389\/fonc.2016.00129","journal-title":"Front Oncol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2017.01.020","article-title":"Preliminary results of a phase 1 dose-escalation trial for early-stage breast cancer using 5-fraction stereotactic body radiation therapy for partial-breast irradiation","volume":"98","author":"Rahimi A","year":"2017","unstructured":"Rahimi A, Thomas K, Spangler A, et al.. Preliminary results of a phase 1 dose-escalation trial for early-stage breast cancer using 5-fraction stereotactic body radiation therapy for partial-breast irradiation. Int J Radiat Oncol Biol Phys. 2017, 98:196-205.e2. 10.1016\/j.ijrobp.2017.01.020","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-018-0991-4","article-title":"Partial breast irradiation with CyberKnife after breast conserving surgery: a pilot study in early breast cancer","volume":"13","author":"Lozza L","year":"2018","unstructured":"Lozza L, Fariselli L, Sandri M, et al.. Partial breast irradiation with CyberKnife after breast conserving surgery: a pilot study in early breast cancer. Radiat Oncol. 2018, 13:49. 10.1186\/s13014-018-0991-4","journal-title":"Radiat Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2022.101095","article-title":"Robotic stereotactic body radiation therapy for the adjuvant treatment of early-stage breast cancer: outcomes of a large single-institution study","volume":"8","author":"Jaysing A","year":"2023","unstructured":"Jaysing A, Lischalk JW, Sanchez A, et al.. Robotic stereotactic body radiation therapy for the adjuvant treatment of early-stage breast cancer: outcomes of a large single-institution study. Adv Radiat Oncol. 2023, 8:101095. 10.1016\/j.adro.2022.101095","journal-title":"Adv Radiat Oncol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2023.05.018","article-title":"Cosmetic outcome and toxicity after stereotactic accelerated partial breast irradiation in early breast cancer: a prospective observational cohort study","volume":"117","author":"Byun HK","year":"2023","unstructured":"Byun HK, Chang JS, Kim H, et al.. Cosmetic outcome and toxicity after stereotactic accelerated partial breast irradiation in early breast cancer: a prospective observational cohort study. Int J Radiat Oncol Biol Phys. 2023, 117:690-700. 10.1016\/j.ijrobp.2023.05.018","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2024.103796","article-title":"Stereotactic body radiotherapy using CyberKnife versus interstitial brachytherapy in accelerated partial breast irradiation on left-sided breast: a comparison of dosimetric characteristics and preliminary clinical results","volume":"78","author":"Wei TN","year":"2024","unstructured":"Wei TN, Lin JF, Cheng MC, Yeh HL. Stereotactic body radiotherapy using CyberKnife versus interstitial brachytherapy in accelerated partial breast irradiation on left-sided breast: a comparison of dosimetric characteristics and preliminary clinical results. Breast. 2024, 78:103796. 10.1016\/j.breast.2024.103796","journal-title":"Breast"},{"key":"ref15","unstructured":"Accuray Incorporated. CyberKnife System. (2024). https.\/\/cyberknife.com\/cyberknife-technology\/."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page MJ","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, et al.. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021, 372:n71. 10.1136\/bmj.n71","journal-title":"BMJ"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s12253-020-00821-3","article-title":"Implementation of stereotactic accelerated partial breast irradiation using Cyber-Knife - technical considerations and early experiences of a phase II clinical study","volume":"26","author":"M\u00e9sz\u00e1ros N","year":"2020","unstructured":"M\u00e9sz\u00e1ros N, Smanyk\u00f3 V, Major T, et al.. Implementation of stereotactic accelerated partial breast irradiation using Cyber-Knife - technical considerations and early experiences of a phase II clinical study. Pathol Oncol Res. 2020, 26:2307-13. 10.1007\/s12253-020-00821-3","journal-title":"Pathol Oncol Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.2147\/BCTT.S555446","article-title":"Stereotactic accelerated partial breast irradiation using CyberKnife with non-invasive skin fiducial marker tracking in early-stage breast cancer: a retrospective study of feasibility, dosimetry, and early outcomes","volume":"17","author":"Wei CW","year":"2025","unstructured":"Wei CW, Cheng MC, Yeh HL. Stereotactic accelerated partial breast irradiation using CyberKnife with non-invasive skin fiducial marker tracking in early-stage breast cancer: a retrospective study of feasibility, dosimetry, and early outcomes. Breast Cancer (Dove Med Press). 2025, 17:997-1004. 10.2147\/BCTT.S555446","journal-title":"Breast Cancer (Dove Med Press)"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1118\/1.4757616","article-title":"Dosimetric investigation of accelerated partial breast irradiation (APBI) using CyberKnife","volume":"39","author":"Xu Q","year":"2012","unstructured":"Xu Q, Chen Y, Grimm J, et al.. Dosimetric investigation of accelerated partial breast irradiation (APBI) using CyberKnife. Med Phys. 2012, 39:6621-8. 10.1118\/1.4757616","journal-title":"Med Phys"},{"key":"ref20","article-title":"Five-year outcomes of robotic stereotactic accelerated partial breast irradiation for early-stage breast cancer","author":"Sherman T","year":"2025","unstructured":"Sherman T. Five-year outcomes of robotic stereotactic accelerated partial breast irradiation for early-stage breast cancer. ASTRO Poster Library. American Society for Radiation Oncology, Arlington, VA; 2025."},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1017\/S146039692000120X","article-title":"Stereotactic body radiotherapy in Cyberknife\u00ae for partial breast irradiation: a review","volume":"21","author":"De la Pinta C","year":"2022","unstructured":"De la Pinta C, Fern\u00e1ndez-Lizarbe E. Stereotactic body radiotherapy in Cyberknife\u00ae for partial breast irradiation: a review. J Radiother Pract. 2022, 21:411-5. 10.1017\/S146039692000120X","journal-title":"J Radiother Pract"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.5603\/RPOR.a2022.0011","article-title":"CyberKnife versus multicatheter interstitial brachytherapy for accelerated partial breast irradiation: a dosimetrical assessment with focus on organs at risk","volume":"27","author":"Herein A","year":"2022","unstructured":"Herein A, Stelczer G, Peszny\u00e1k C, et al.. CyberKnife versus multicatheter interstitial brachytherapy for accelerated partial breast irradiation: a dosimetrical assessment with focus on organs at risk. Rep Pract Oncol Radiother. 2022, 27:152-60. 10.5603\/RPOR.a2022.0011","journal-title":"Rep Pract Oncol Radiother"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1177\/1533034615601280","article-title":"Dosimetric comparison between 3-dimensional conformal and robotic SBRT treatment plans for accelerated partial breast radiotherapy","volume":"15","author":"Goggin LM","year":"2016","unstructured":"Goggin LM, Descovich M, McGuinness C, Shiao S, Pouliot J, Park C. Dosimetric comparison between 3-dimensional conformal and robotic SBRT treatment plans for accelerated partial breast radiotherapy. Technol Cancer Res Treat. 2016, 15:437-45. 10.1177\/1533034615601280","journal-title":"Technol Cancer Res Treat"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2012.09.020","article-title":"Five-year outcomes and toxicities using 3-dimensional conformal external beam radiation therapy to deliver accelerated partial breast irradiation","volume":"13","author":"Shah C","year":"2013","unstructured":"Shah C, Wilkinson JB, Lanni T, et al.. Five-year outcomes and toxicities using 3-dimensional conformal external beam radiation therapy to deliver accelerated partial breast irradiation. Clin Breast Cancer. 2013, 13:206-11. 10.1016\/j.clbc.2012.09.020","journal-title":"Clin Breast Cancer"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/467082-clinical-outcomes-of-robotic-stereotactic-accelerated-partial-breast-irradiation-a-structured-literature-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T15:21:16Z","timestamp":1781968876000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/467082-clinical-outcomes-of-robotic-stereotactic-accelerated-partial-breast-irradiation-a-structured-literature-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,20]]},"references-count":24,"URL":"https:\/\/doi.org\/10.7759\/cureus.111198","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,20]]}}}