{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T06:49:04Z","timestamp":1782110944070,"version":"3.54.5"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,21]]},"DOI":"10.7759\/cureus.111266","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T06:24:26Z","timestamp":1782109466000},"source":"Crossref","is-referenced-by-count":0,"title":["From Granulomas to Malignancy: Validating the Sydney System in a Tuberculosis-Endemic Landscape"],"prefix":"10.7759","author":[{"given":"Joyeeta","family":"Mandal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sona","family":"Pathak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arpana S","family":"Tirkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susruta","family":"Sen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minakshi","family":"Karmakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirmalya","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudip","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivedita","family":"Bhattacharjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.18203\/issn.2454-5929.ijohns20171176","article-title":"Cervical lymphadenopathy: a clinicopathological study","volume":"3","author":"Motiwala MA","year":"2017","unstructured":"Motiwala MA, Dalmia D, Behara SK. Cervical lymphadenopathy: a clinicopathological study. Int J Otorhinolaryngol Head Neck Surg. 2017, 3:210-5. 10.18203\/issn.2454-5929.ijohns20171176","journal-title":"Int J Otorhinolaryngol Head Neck Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000550408","article-title":"The critical role of ancillary testing in fine-needle aspiration of lymph nodes, thymus, and spleen","author":"Baptista DA","year":"2026","unstructured":"Baptista DA, Barroca H, Schmitt FC. The critical role of ancillary testing in fine-needle aspiration of lymph nodes, thymus, and spleen. Acta Cytol. 2026, 1-12. 10.1159\/000550408","journal-title":"Acta Cytol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2025.108125","article-title":"Incidence of tubercular lymphadenitis in cases of cervical lymphadenopathy by fine needle aspiration cytology-a single center study","volume":"161","author":"Chand V","year":"2025","unstructured":"Chand V, Katara A, Chand S, Vishwakarma S, Chaudhry V, Chandra H. Incidence of tubercular lymphadenitis in cases of cervical lymphadenopathy by fine needle aspiration cytology-a single center study. Int J Infect Dis. 2025, 161:108125. 10.1016\/j.ijid.2025.108125","journal-title":"Int J Infect Dis"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159\/000506497","article-title":"A proposal for the performance, classification, and reporting of lymph node fine-needle aspiration cytopathology: the Sydney system","volume":"64","author":"Al-Abbadi MA","year":"2020","unstructured":"Al-Abbadi MA, Barroca H, Bode-Lesniewska B, et al.. A proposal for the performance, classification, and reporting of lymph node fine-needle aspiration cytopathology: the Sydney system. Acta Cytol. 2020, 64:306-22. 10.1159\/000506497","journal-title":"Acta Cytol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000548199","article-title":"The World Health Organization reporting system for lymph node, spleen, and thymus cytopathology: part 1 - lymph node","volume":"70","author":"Cozzolino I","year":"2026","unstructured":"Cozzolino I, Ehinger M, Calaminici M, et al.. The World Health Organization reporting system for lymph node, spleen, and thymus cytopathology: part 1 - lymph node. Acta Cytol. 2026, 70:185-200. 10.1159\/000548199","journal-title":"Acta Cytol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.14218\/jctp.2023.00044","article-title":"Introduction of the WHO reporting system for lymph node cytopathology","volume":"4","author":"Gao Y","year":"2023","unstructured":"Gao Y, Monaco SE, Katz RL, Zhang H. Introduction of the WHO reporting system for lymph node cytopathology. J Clin Transl Pathol. 2023, 4:36-43. 10.14218\/jctp.2023.00044","journal-title":"J Clin Transl Pathol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2023.07.066","article-title":"Evaluation of the Sydney system for reporting lymph node cytology - a retrospective study from Northern India","volume":"12","author":"Gupta A","year":"2023","unstructured":"Gupta A, Mehendiratta O, Awasthi N, Singh P, Sachan R. Evaluation of the Sydney system for reporting lymph node cytology - a retrospective study from Northern India. J Am Soc Cytopathol. 2023, 12:37-8. 10.1016\/j.jasc.2023.07.066","journal-title":"J Am Soc Cytopathol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/joc.joc_20_24","article-title":"Evaluation of fine-needle aspiration of lymph nodes and assessment of risk of malignancy based on the Sydney system of reporting lymph node cytology","volume":"42","author":"Ghosh S","year":"2024","unstructured":"Ghosh S, Guha P, Verma S, Gupta N, Vimal JK, Prasad P, Pant G. Evaluation of fine-needle aspiration of lymph nodes and assessment of risk of malignancy based on the Sydney system of reporting lymph node cytology. J Cytol. 2024, 42:11-9. 10.4103\/joc.joc_20_24","journal-title":"J Cytol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.18203\/2320-6012.ijrms20252886","article-title":"Application of the Sydney system for classification and reporting lymph node cytopathology: a retrospective analysis at a tertiary centre","volume":"13","author":"Kummari AT","year":"2025","unstructured":"Kummari AT, Pamu PK, Ganna KK, Jyothi P, Sadashivudu. Application of the Sydney system for classification and reporting lymph node cytopathology: a retrospective analysis at a tertiary centre. Int J Res Med Sci. 2025, 13:4029-34. 10.18203\/2320-6012.ijrms20252886","journal-title":"Int J Res Med Sci"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/dc.70053","article-title":"Assessment of risk of malignancy using the Sydney system for reporting head and neck lymph node cytopathology: an institutional experience","volume":"54","author":"Sushma B","year":"2026","unstructured":"Sushma B, Renu S, Manupriya S, Potdar P. Assessment of risk of malignancy using the Sydney system for reporting head and neck lymph node cytopathology: an institutional experience. Diagn Cytopathol. 2026, 54:125-34. 10.1002\/dc.70053","journal-title":"Diagn Cytopathol"},{"key":"ref11","unstructured":"Global tuberculosis reports, 1997 to 2025. (2024). Accessed. March 20, 2026: https:\/\/www.who.int\/teams\/global-programme-on-tuberculosis-and-lung-health\/tb-reports."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.14744\/nci.2016.20982","article-title":"Diagnostic challenges in cervical tuberculous lymphadenitis: a review","volume":"3","author":"Deveci HS","year":"2016","unstructured":"Deveci HS, Kule M, Kule ZA, Habesoglu TE. Diagnostic challenges in cervical tuberculous lymphadenitis: a review. North Clin Istanb. 2016, 3:150-5. 10.14744\/nci.2016.20982","journal-title":"North Clin Istanb"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmic.2024.100116","article-title":"Diagnosis of tuberculous lymphadenitis by molecular and immunological tools","volume":"22","author":"Kumar N","year":"2024","unstructured":"Kumar N, Khan A, Boora S, et al.. Diagnosis of tuberculous lymphadenitis by molecular and immunological tools. Med Microecol. 2024, 22:100116. 10.1016\/j.medmic.2024.100116","journal-title":"Med Microecol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22432","article-title":"Assessment of risk of malignancy by application of the proposed Sydney system for classification and reporting lymph node cytopathology","volume":"129","author":"Gupta P","year":"2021","unstructured":"Gupta P, Gupta N, Kumar P, et al.. Assessment of risk of malignancy by application of the proposed Sydney system for classification and reporting lymph node cytopathology. Cancer Cytopathol. 2021, 129:701-18. 10.1002\/cncy.22432","journal-title":"Cancer Cytopathol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14161801","article-title":"Sydney reporting system for lymph node fine-needle aspiration and malignancy risk stratification: is it of clinical value?","volume":"14","author":"Alqaidy D","year":"2024","unstructured":"Alqaidy D, Althomali H, Almaghrabi A. Sydney reporting system for lymph node fine-needle aspiration and malignancy risk stratification: is it of clinical value?. Diagnostics (Basel). 2024, 14:1801. 10.3390\/diagnostics14161801","journal-title":"Diagnostics (Basel)"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.143.1.7063747","article-title":"The meaning and use of the area under a receiver operating characteristic (ROC) curve","volume":"143","author":"Hanley JA","year":"1982","unstructured":"Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982, 143:29-36. 10.1148\/radiology.143.1.7063747","journal-title":"Radiology"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1177\/001316446002000104","article-title":"A coefficient of agreement for nominal scales","volume":"20","author":"Cohen J","year":"1960","unstructured":"Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas. 1960, 20:37-46. 10.1177\/001316446002000104","journal-title":"Educ Psychol Meas"},{"key":"ref18","doi-asserted-by":"crossref","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis JR","year":"1977","unstructured":"Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977, 33:159-74.","journal-title":"Biometrics"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.51.3.197","article-title":"Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia","volume":"51","author":"Stewart CJ","year":"1998","unstructured":"Stewart CJ, Duncan JA, Farquharson M, Richmond J. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. J Clin Pathol. 1998, 51:197-203. 10.1136\/jcp.51.3.197","journal-title":"J Clin Pathol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.52.1","article-title":"Granulomatous lymphadenitis","volume":"52","author":"Asano S","year":"2012","unstructured":"Asano S. Granulomatous lymphadenitis. J Clin Exp Hematop. 2012, 52:1-16. 10.3960\/jslrt.52.1","journal-title":"J Clin Exp Hematop"},{"key":"ref21","article-title":"INDEX-TB Guidelines: Guidelines on Extra-pulmonary Tuberculosis for India (2023 update)","author":"World Health Organization","year":"2023","unstructured":"World Health Organization. INDEX-TB Guidelines: Guidelines on Extra-pulmonary Tuberculosis for India. World Health Organization, Geneva, Switzerland; 2023. https:\/\/tbcindia.mohfw.gov.in\/wp-content\/uploads\/2023\/05\/5585665076Index-TB-Guidelines.pdf."}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/496176-from-granulomas-to-malignancy-validating-the-sydney-system-in-a-tuberculosis-endemic-landscape","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T06:24:33Z","timestamp":1782109473000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/496176-from-granulomas-to-malignancy-validating-the-sydney-system-in-a-tuberculosis-endemic-landscape"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,21]]},"references-count":21,"URL":"https:\/\/doi.org\/10.7759\/cureus.111266","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,21]]}}}