{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:47:41Z","timestamp":1782175661314,"version":"3.54.5"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,22]]},"DOI":"10.7759\/cureus.111313","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:26Z","timestamp":1782172826000},"source":"Crossref","is-referenced-by-count":0,"title":["Weight Loss Following Liraglutide Therapy in a Patient With Smith-Magenis Syndrome: A Case Report"],"prefix":"10.7759","author":[{"given":"Dave K","family":"Garg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2015.08.011","article-title":"Individuals with Smith-Magenis syndrome display profound neurodevelopmental behavioral deficiencies and exhibit food-related behaviors equivalent to Prader-Willi syndrome","volume":"47","author":"Alaimo JT","year":"2015","unstructured":"Alaimo JT, Barton LV, Mullegama SV, Wills RD, Foster RH, Elsea SH. Individuals with Smith-Magenis syndrome display profound neurodevelopmental behavioral deficiencies and exhibit food-related behaviors equivalent to Prader-Willi syndrome. Res Dev Disabil. 2015, 47:27-38. 10.1016\/j.ridd.2015.08.011","journal-title":"Res Dev Disabil"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206038","article-title":"Tirzepatide once weekly for the treatment of obesity","volume":"387","author":"Jastreboff AM","year":"2022","unstructured":"Jastreboff AM, Aronne LJ, Ahmad NN, et al.. Tirzepatide once weekly for the treatment of obesity. N Engl J Med. 2022, 387:205-16. 10.1056\/NEJMoa2206038","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s44162-026-00193-3","article-title":"Investigating food-related behaviors in Smith-Magenis syndrome: tailoring a questionnaire for a rare disease","volume":"5","author":"Elatrash C","year":"2026","unstructured":"Elatrash C, Wilson TA, Wood AC, Elsea SH, Sisley S. Investigating food-related behaviors in Smith-Magenis syndrome: tailoring a questionnaire for a rare disease. J Rare Dis (Berlin). 2026, 5:49. 10.1007\/s44162-026-00193-3","journal-title":"J Rare Dis (Berlin)"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s13679-023-00543-y","article-title":"A comprehensive review of syndromic forms of obesity: genetic etiology, clinical features and molecular diagnosis","volume":"13","author":"Carvalho LM","year":"2024","unstructured":"Carvalho LM, Jorge AA, Bertola DR, Krepischi AC, Rosenberg C. A comprehensive review of syndromic forms of obesity: genetic etiology, clinical features and molecular diagnosis. Curr Obes Rep. 2024, 13:313-37. 10.1007\/s13679-023-00543-y","journal-title":"Curr Obes Rep"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3390\/genes13020335","article-title":"Smith-Magenis syndrome-clinical review, biological background and related disorders","volume":"13","author":"Rinaldi B","year":"2022","unstructured":"Rinaldi B, Villa R, Sironi A, Garavelli L, Finelli P, Bedeschi MF. Smith-Magenis syndrome-clinical review, biological background and related disorders. Genes (Basel). 2022, 13:10.3390\/genes13020335","journal-title":"Genes (Basel)"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00125817-200205000-00004","article-title":"Hypercholesterolemia in children with Smith-Magenis syndrome: del (17) (p11.2p11.2)","volume":"4","author":"Smith AC","year":"2002","unstructured":"Smith AC, Gropman AL, Bailey-Wilson JE, et al.. Hypercholesterolemia in children with Smith-Magenis syndrome: del (17) (p11.2p11.2). Genet Med. 2002, 4:118-25. 10.1097\/00125817-200205000-00004","journal-title":"Genet Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.gimo.2024.101857","article-title":"Blind to the perils of pursuing food: behaviors of individuals with Smith-Magenis Syndrome","volume":"2","author":"Elatrash C","year":"2024","unstructured":"Elatrash C, Shi J, Wilson T, Elsea SH, Sisley S. Blind to the perils of pursuing food: behaviors of individuals with Smith-Magenis Syndrome. Genet Med Open. 2024, 2:10.1016\/j.gimo.2024.101857","journal-title":"Genet Med Open"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnaf004","article-title":"Antiobesity pharmacotherapy for patients with genetic obesity due to defects in the leptin-melanocortin pathway","volume":"46","author":"Welling MS","year":"2025","unstructured":"Welling MS, van Rossum EF, van den Akker EL. Antiobesity pharmacotherapy for patients with genetic obesity due to defects in the leptin-melanocortin pathway. Endocr Rev. 2025, 46:418-46. 10.1210\/endrev\/bnaf004","journal-title":"Endocr Rev"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.orcp.2024.07.001","article-title":"Investigation of setmelanotide, an MC4R agonist, for obesity in individuals with Smith-Magenis syndrome","volume":"18","author":"Lazareva J","year":"2024","unstructured":"Lazareva J, Sisley SR, Brady SM, et al.. Investigation of setmelanotide, an MC4R agonist, for obesity in individuals with Smith-Magenis syndrome. Obes Res Clin Pract. 2024, 18:301-7. 10.1016\/j.orcp.2024.07.001","journal-title":"Obes Res Clin Pract"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/oby.23385","article-title":"Critical review of bariatric surgical outcomes in patients with Prader-Willi syndrome and other hyperphagic disorders","volume":"30","author":"Gantz MG","year":"2022","unstructured":"Gantz MG, Driscoll DJ, Miller JL, et al.. Critical review of bariatric surgical outcomes in patients with Prader-Willi syndrome and other hyperphagic disorders. Obesity (Silver Spring). 2022, 30:973-81. 10.1002\/oby.23385","journal-title":"Obesity (Silver Spring)"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-016-3874-y","article-title":"GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial","volume":"59","author":"Farr OM","year":"2016","unstructured":"Farr OM, Sofopoulos M, Tsoukas MA, et al.. GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial. Diabetologia. 2016, 59:954-65. 10.1007\/s00125-016-3874-y","journal-title":"Diabetologia"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113537","article-title":"Neuroprotective effects of GLP-1 receptor agonists in neurodegenerative disorders: a large-scale propensity-matched cohort study","volume":"143","author":"Siddeeque N","year":"2024","unstructured":"Siddeeque N, Hussein MH, Abdelmaksoud A, et al.. Neuroprotective effects of GLP-1 receptor agonists in neurodegenerative disorders: a large-scale propensity-matched cohort study. Int Immunopharmacol. 2024, 143:113537. 10.1016\/j.intimp.2024.113537","journal-title":"Int Immunopharmacol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-022-03064-1","article-title":"Intensive management of obesity in people with Prader-Willi syndrome","volume":"77","author":"Nolan BJ","year":"2022","unstructured":"Nolan BJ, Proietto J, Sumithran P. Intensive management of obesity in people with Prader-Willi syndrome. Endocrine. 2022, 77:57-62. 10.1007\/s12020-022-03064-1","journal-title":"Endocrine"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12546","article-title":"Weight loss with glucagon-like peptide-1 receptor agonists in Bardet-Biedl syndrome","volume":"12","author":"Ganawa S","year":"2022","unstructured":"Ganawa S, Santhosh SH, Parry L, Syed AA. Weight loss with glucagon-like peptide-1 receptor agonists in Bardet-Biedl syndrome. Clin Obes. 2022, 12:e12546. 10.1111\/cob.12546","journal-title":"Clin Obes"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.05.008","article-title":"Patients with obesity caused by melanocortin-4 receptor mutations can be treated with a glucagon-like peptide-1 receptor agonist","volume":"28","author":"Iepsen EW","year":"2018","unstructured":"Iepsen EW, Zhang J, Thomsen HS, et al.. Patients with obesity caused by melanocortin-4 receptor mutations can be treated with a glucagon-like peptide-1 receptor agonist. Cell Metab. 2018, 28:23-32.e3. 10.1016\/j.cmet.2018.05.008","journal-title":"Cell Metab"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1528457","article-title":"Case report: long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review","volume":"15","author":"Koceva A","year":"2024","unstructured":"Koceva A, Mleku\u0161 Kozamernik K, Jane\u017e A, Herman R, Ferjan S, Jensterle M. Case report: long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review. Front Endocrinol (Lausanne). 2024, 15:1528457. 10.3389\/fendo.2024.1528457","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/cen.14583","article-title":"The effects of glucagon-like peptide (GLP)-1 receptor agonists on weight and glycaemic control in Prader-Willi syndrome: a systematic review","volume":"96","author":"Ng NB","year":"2022","unstructured":"Ng NB, Low YW, Rajgor DD, Low JM, Lim YY, Loke KY, Lee YS. The effects of glucagon-like peptide (GLP)-1 receptor agonists on weight and glycaemic control in Prader-Willi syndrome: a systematic review. Clin Endocrinol (Oxf). 2022, 96:144-54. 10.1111\/cen.14583","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1210\/jcemcr\/luaf094","article-title":"Weight management in a patient with Smith-Magenis syndrome: the role of GLP-1 receptor agonists","volume":"3","author":"Correia JC","year":"2025","unstructured":"Correia JC, Frayling T, Pataky Z. Weight management in a patient with Smith-Magenis syndrome: the role of GLP-1 receptor agonists. JCEM Case Rep. 2025, 3:luaf094. 10.1210\/jcemcr\/luaf094","journal-title":"JCEM Case Rep"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.2337\/dc24-1678","article-title":"Efficacy of GLP-1 receptor agonists on weight loss, BMI, and waist circumference for patients with obesity or overweight: a systematic review, meta-analysis, and meta-regression of 47 randomized controlled trials","volume":"48","author":"Wong HJ","year":"2025","unstructured":"Wong HJ, Sim B, Teo YH, et al.. Efficacy of GLP-1 receptor agonists on weight loss, BMI, and waist circumference for patients with obesity or overweight: a systematic review, meta-analysis, and meta-regression of 47 randomized controlled trials. Diabetes Care. 2025, 48:292-300. 10.2337\/dc24-1678","journal-title":"Diabetes Care"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/53.6.1404","article-title":"The transient hypercholesterolemia of major weight loss","volume":"53","author":"Phinney SD","year":"1991","unstructured":"Phinney SD, Tang AB, Waggoner CR, Tezanos-Pinto RG, Davis PA. The transient hypercholesterolemia of major weight loss. Am J Clin Nutr. 1991, 53:1404-10. 10.1093\/ajcn\/53.6.1404","journal-title":"Am J Clin Nutr"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/503553-weight-loss-following-liraglutide-therapy-in-a-patient-with-smith-magenis-syndrome-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:27Z","timestamp":1782172827000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/503553-weight-loss-following-liraglutide-therapy-in-a-patient-with-smith-magenis-syndrome-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,22]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.111313","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,22]]}}}