{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T09:46:24Z","timestamp":1782639984657,"version":"3.54.5"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,28]]},"DOI":"10.7759\/cureus.111646","type":"journal-article","created":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T09:43:07Z","timestamp":1782639787000},"source":"Crossref","is-referenced-by-count":0,"title":["Recurrent Fever and Biliary Ectasia Leading to the Diagnosis of Caroli Syndrome: A Diagnostic Challenge"],"prefix":"10.7759","author":[{"given":"Muhammad","family":"Usman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Basit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal Ahmad","family":"Buttar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Aftab","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laiba","family":"Murtaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Caroli disease","author":"Kyalwazi B","year":"2026","unstructured":"Kyalwazi B, Kudaravalli P, John S. Caroli disease. StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL); 2026."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2024.00119","article-title":"Heritable chronic cholestatic liver diseases: a review","volume":"12","author":"Tidwell J","year":"2024","unstructured":"Tidwell J, Wu GY. Heritable chronic cholestatic liver diseases: a review. J Clin Transl Hepatol. 2024, 12:726-38. 10.14218\/JCTH.2024.00119","journal-title":"J Clin Transl Hepatol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-020-01442-5","article-title":"Factors contributing to diagnostic delay of Caroli syndrome: a single-center, retrospective study","volume":"20","author":"Shi W","year":"2020","unstructured":"Shi W, Huang XM, Feng YL, Wang FD, Gao XX, Jiao Y. Factors contributing to diagnostic delay of Caroli syndrome: a single-center, retrospective study. BMC Gastroenterol. 2020, 20:317. 10.1186\/s12876-020-01442-5","journal-title":"BMC Gastroenterol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/livers1030012","article-title":"Congenital hepatic fibrosis as a cause of recurrent cholangitis: a case report and review of the literature","volume":"1","author":"Palomba E","year":"2021","unstructured":"Palomba E, Maggioni M, Viero G, et al.. Congenital hepatic fibrosis as a cause of recurrent cholangitis: a case report and review of the literature. Livers. 2021, 1:132-7. 10.3390\/livers1030012","journal-title":"Livers"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2017.00114","article-title":"A challenging case of hepatoblastoma concomitant with autosomal recessive polycystic kidney disease and Caroli syndrome: review of the literature","volume":"5","author":"Kadakia N","year":"2017","unstructured":"Kadakia N, Lobritto SJ, Ovchinsky N, Remotti HE, Yamashiro DJ, Emond JC, Martinez M. A challenging case of hepatoblastoma concomitant with autosomal recessive polycystic kidney disease and Caroli syndrome: review of the literature. Front Pediatr. 2017, 5:114. 10.3389\/fped.2017.00114","journal-title":"Front Pediatr"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-022-01242-3","article-title":"Cystic liver lesions: a pictorial review","volume":"13","author":"Chenin M","year":"2022","unstructured":"Chenin M, Paisant A, Lebigot J, et al.. Cystic liver lesions: a pictorial review. Insights Imaging. 2022, 13:116. 10.1186\/s13244-022-01242-3","journal-title":"Insights Imaging"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v26.i31.4718","article-title":"Risk of malignancy in Caroli disease and syndrome: a systematic review","volume":"26","author":"Fahrner R","year":"2020","unstructured":"Fahrner R, Dennler SG, Inderbitzin D. Risk of malignancy in Caroli disease and syndrome: a systematic review. World J Gastroenterol. 2020, 26:4718-28. 10.3748\/wjg.v26.i31.4718","journal-title":"World J Gastroenterol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.1998","article-title":"Rare variants in PKHD1 associated with Caroli syndrome: two case reports","volume":"10","author":"Giacobbe C","year":"2022","unstructured":"Giacobbe C, Di Dato F, Palma D, Amitrano M, Iorio R, Fortunato G. Rare variants in PKHD1 associated with Caroli syndrome: two case reports. Mol Genet Genomic Med. 2022, 10:e1998. 10.1002\/mgg3.1998","journal-title":"Mol Genet Genomic Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2025.12.573","article-title":"Adult-onset Caroli syndrome: a diagnostic challenge","volume":"371","author":"Gatiganti A","year":"2026","unstructured":"Gatiganti A, Fitzgerald C. Adult-onset Caroli syndrome: a diagnostic challenge. Am J Med Sci. 2026, 371:355. 10.1016\/j.amjms.2025.12.573","journal-title":"Am J Med Sci"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/499408-recurrent-fever-and-biliary-ectasia-leading-to-the-diagnosis-of-caroli-syndrome-a-diagnostic-challenge","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T09:43:08Z","timestamp":1782639788000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/499408-recurrent-fever-and-biliary-ectasia-leading-to-the-diagnosis-of-caroli-syndrome-a-diagnostic-challenge"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,28]]},"references-count":9,"URL":"https:\/\/doi.org\/10.7759\/cureus.111646","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,28]]}}}