{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T06:45:49Z","timestamp":1782801949967,"version":"3.54.5"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,29]]},"DOI":"10.7759\/cureus.111779","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T06:17:01Z","timestamp":1782800221000},"source":"Crossref","is-referenced-by-count":0,"title":["Gilteritinib-Associated Hypertriglyceridemia During Acute Myeloid Leukemia Triplet Therapy in a 52-Year-Old Man: A Case Report"],"prefix":"10.7759","author":[{"given":"Bhargav","family":"Vuppumalla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karna","family":"Jagatheeswaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhath Surya","family":"Katta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaitanya Kumar","family":"Javvaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Analysis of correlation between serum thymidine kinase 1 and acute myeloid leukemia [Article in Chinese]","volume":"21","author":"Wang TJ","year":"2013","unstructured":"Wang TJ, Sun AN, Wu DP, Li WY, Liang JY. Analysis of correlation between serum thymidine kinase 1 and acute myeloid leukemia [Article in Chinese]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013, 21:1095-8.","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000040565","article-title":"Acute myeloid leukemia treatment outcomes with isocitrate dehydrogenase mutations: a systematic review and meta-analysis","volume":"103","author":"Qin H","year":"2024","unstructured":"Qin H, Xu R, Yang Y. Acute myeloid leukemia treatment outcomes with isocitrate dehydrogenase mutations: a systematic review and meta-analysis. Medicine (Baltimore). 2024, 103:e40565. 10.1097\/MD.0000000000040565","journal-title":"Medicine (Baltimore)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.5644\/ama2006-124.453","article-title":"The role of FLT3-ITD mutation, PI3K\/AKT pathway, and leukemia stem cells in D3A7 induction therapy - the outcomes of adult Indonesian patients with acute myeloid leukemia","volume":"53","author":"Arwanih EY","year":"2024","unstructured":"Arwanih EY, Rinaldi I, Wanandi SI, Louisa M. The role of FLT3-ITD mutation, PI3K\/AKT pathway, and leukemia stem cells in D3A7 induction therapy - the outcomes of adult Indonesian patients with acute myeloid leukemia. Acta Med Acad. 2024, 53:165-75. 10.5644\/ama2006-124.453","journal-title":"Acta Med Acad"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1254\/fpj.20050","article-title":"Pharmacological and clinical profile of gilteritinib (Xospata(\u00ae) tablets 40\u2005mg), a therapeutic agent for relapsed or refractory FLT3-mutated acute myeloid leukemia [Article in Japanese]","volume":"156","author":"Mori M","year":"2021","unstructured":"Mori M, Hidaka K. Pharmacological and clinical profile of gilteritinib (Xospata(\u00ae) tablets 40\u2005mg), a therapeutic agent for relapsed or refractory FLT3-mutated acute myeloid leukemia [Article in Japanese]. Nihon Yakurigaku Zasshi. 2021, 156:37-46. 10.1254\/fpj.20050","journal-title":"Nihon Yakurigaku Zasshi"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2020.21.10.2827","article-title":"Prognostic significance of FMS-like tyrosine kinase 3 internal tandem duplication mutation in non-transplant adult patients with acute myeloblastic leukemia: a systematic review and meta-analysis","volume":"21","author":"Rinaldi I","year":"2020","unstructured":"Rinaldi I, Louisa M, Wiguna FI, Budiani E, Mahardhika JC, Hukmi K. Prognostic significance of FMS-like tyrosine kinase 3 internal tandem duplication mutation in non-transplant adult patients with acute myeloblastic leukemia: a systematic review and meta-analysis. Asian Pac J Cancer Prev. 2020, 21:2827-36. 10.31557\/APJCP.2020.21.10.2827","journal-title":"Asian Pac J Cancer Prev"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.775128","article-title":"Leukemic stem cells: from leukemic niche biology to treatment opportunities","volume":"12","author":"Marchand T","year":"2021","unstructured":"Marchand T, Pinho S. Leukemic stem cells: from leukemic niche biology to treatment opportunities. Front Immunol. 2021, 12:775128. 10.3389\/fimmu.2021.775128","journal-title":"Front Immunol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-019-1062-3","article-title":"Gilteritinib: first global approval","volume":"79","author":"Dhillon S","year":"2019","unstructured":"Dhillon S. Gilteritinib: first global approval. Drugs. 2019, 79:331-9. 10.1007\/s40265-019-1062-3","journal-title":"Drugs"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/jof6040324","article-title":"Isavuconazole: mechanism of action, clinical efficacy, and resistance","volume":"6","author":"Ellsworth M","year":"2020","unstructured":"Ellsworth M, Ostrosky-Zeichner L. Isavuconazole: mechanism of action, clinical efficacy, and resistance. J Fungi (Basel). 2020, 6:10.3390\/jof6040324","journal-title":"J Fungi (Basel)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c05666","article-title":"Effects of the fungicide prothioconazole on lipid metabolism in mice: whitening alterations of brown adipose tissue","volume":"58","author":"Song SL","year":"2024","unstructured":"Song SL, Chen XY, Zhao J, et al.. Effects of the fungicide prothioconazole on lipid metabolism in mice: whitening alterations of brown adipose tissue. Environ Sci Technol. 2024, 58:18155-66. 10.1021\/acs.est.4c05666","journal-title":"Environ Sci Technol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2024.286427","article-title":"Venetoclax in combination with a pediatric-inspired regimen for the treatment of newly diagnosed adults with Philadelphia chromosome-negative acute lymphoblastic leukemia","volume":"110","author":"Aldoss I","year":"2025","unstructured":"Aldoss I, Zhang J, Shimamoto K, et al.. Venetoclax in combination with a pediatric-inspired regimen for the treatment of newly diagnosed adults with Philadelphia chromosome-negative acute lymphoblastic leukemia. Haematologica. 2025, 110:1105-14. 10.3324\/haematol.2024.286427","journal-title":"Haematologica"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.577796","article-title":"Hypertriglyceridemia in newly diagnosed\u00a0acute promyelocytic leukemia","volume":"10","author":"Sun J","year":"2020","unstructured":"Sun J, Lou Y, Zhu J, et al.. Hypertriglyceridemia in newly diagnosed\u00a0acute promyelocytic leukemia. Front Oncol. 2020, 10:577796. 10.3389\/fonc.2020.577796","journal-title":"Front Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0000000000001470","article-title":"Gilteritinib-induced severe immune-related enteritis: a possible case report","volume":"34","author":"Luo P","year":"2023","unstructured":"Luo P, Qiu H, Yang Y, et al.. Gilteritinib-induced severe immune-related enteritis: a possible case report. Anticancer Drugs. 2023, 34:896-900. 10.1097\/CAD.0000000000001470","journal-title":"Anticancer Drugs"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154","article-title":"A method for estimating the probability of adverse drug reactions","volume":"30","author":"Naranjo CA","year":"1981","unstructured":"Naranjo CA, Busto U, Sellers EM, et al.. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981, 30:239-45. 10.1038\/clpt.1981.154","journal-title":"Clin Pharmacol Ther"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/498611-gilteritinib-associated-hypertriglyceridemia-during-acute-myeloid-leukemia-triplet-therapy-in-a-52-year-old-man-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T06:17:01Z","timestamp":1782800221000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/498611-gilteritinib-associated-hypertriglyceridemia-during-acute-myeloid-leukemia-triplet-therapy-in-a-52-year-old-man-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,29]]},"references-count":13,"URL":"https:\/\/doi.org\/10.7759\/cureus.111779","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,29]]}}}