{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T19:26:57Z","timestamp":1783279617099,"version":"3.54.6"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,5]]},"DOI":"10.7759\/cureus.112100","type":"journal-article","created":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T18:23:18Z","timestamp":1783275798000},"source":"Crossref","is-referenced-by-count":0,"title":["Cryoglobulinemic Vasculitis: Clinical Analysis of a Case and Its Diagnostic Relevance"],"prefix":"10.7759","author":[{"given":"Valeria Janet","family":"Mart\u00ednez Evangelista","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola V","family":"Rosales Verduzco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Cid-Puente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Laura","family":"Rodr\u00edguez Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Arreola Sevilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-3-25","article-title":"Mixed cryoglobulinemia","volume":"3","author":"Ferri C","year":"2008","unstructured":"Ferri C. Mixed cryoglobulinemia. Orphanet J Rare Dis. 2008, 3:25. 10.1186\/1750-1172-3-25","journal-title":"Orphanet J Rare Dis"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0009-4","article-title":"Cryoglobulinaemia","volume":"4","author":"Roccatello D","year":"2018","unstructured":"Roccatello D, Saadoun D, Ramos-Casals M, et al.. Cryoglobulinaemia. Nat Rev Dis Primers. 2018, 4:11. 10.1038\/s41572-018-0009-4","journal-title":"Nat Rev Dis Primers"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-219768","article-title":"Mixed cryoglobulinemia: a diagnostic and therapeutic challenge","volume":"2017","author":"T\u00falio M","year":"2017","unstructured":"T\u00falio M, Carvalho L, Bana e Costa T, Chagas C. Mixed cryoglobulinemia: a diagnostic and therapeutic challenge. BMJ Case Rep. 2017, 2017:bcr-2017-219768. 10.1136\/bcr-2017-219768","journal-title":"BMJ Case Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000346","article-title":"Approach to cutaneous vasculitides with special emphasis on small vessel vasculitis: histopathology and direct immunofluorescence","volume":"29","author":"Demirkesen C","year":"2017","unstructured":"Demirkesen C. Approach to cutaneous vasculitides with special emphasis on small vessel vasculitis: histopathology and direct immunofluorescence. Curr Opin Rheumatol. 2017, 29:39-44. 10.1097\/BOR.0000000000000346","journal-title":"Curr Opin Rheumatol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28297","article-title":"Treatment of hepatitis C virus-associated mixed cryoglobulinemia with direct-acting antiviral agents","volume":"63","author":"Sise ME","year":"2016","unstructured":"Sise ME, Bloom AK, Wisocky J, et al.. Treatment of hepatitis C virus-associated mixed cryoglobulinemia with direct-acting antiviral agents. Hepatology. 2016, 63:408-17. 10.1002\/hep.28297","journal-title":"Hepatology"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-09-719773","article-title":"How I treat cryoglobulinemia","volume":"129","author":"Muchtar E","year":"2017","unstructured":"Muchtar E, Magen H, Gertz MA. How I treat cryoglobulinemia. Blood. 2017, 129:289-98. 10.1182\/blood-2016-09-719773","journal-title":"Blood"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2011.150755","article-title":"Preliminary classification criteria for the cryoglobulinaemic vasculitis","volume":"70","author":"De Vita S","year":"2011","unstructured":"De Vita S, Soldano F, Isola M, et al.. Preliminary classification criteria for the cryoglobulinaemic vasculitis. Ann Rheum Dis. 2011, 70:1183-90. 10.1136\/ard.2011.150755","journal-title":"Ann Rheum Dis"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/joim.70042","article-title":"Cryoglobulinemia: an update on classification, pathophysiology, clinical presentation, and management","volume":"299","author":"Zignego AL","year":"2026","unstructured":"Zignego AL, Gragnani L, Visentini M, et al.. Cryoglobulinemia: an update on classification, pathophysiology, clinical presentation, and management. J Intern Med. 2026, 299:196-215. 10.1111\/joim.70042","journal-title":"J Intern Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2009.03443.x","article-title":"The histological assessment of cutaneous vasculitis","volume":"56","author":"Carlson JA","year":"2010","unstructured":"Carlson JA. The histological assessment of cutaneous vasculitis. Histopathology. 2010, 56:3-23. 10.1111\/j.1365-2559.2009.03443.x","journal-title":"Histopathology"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.20517\/2574-1209.2023.105","article-title":"Nonviral cryoglobulinemic vasculitis: an updated review for clinical practice","volume":"7","author":"N\u00fa\u00f1ez-Conde A","year":"2023","unstructured":"N\u00fa\u00f1ez-Conde A, de la Hera Fern\u00e1ndez J, Garc\u00eda-M\u00e9ndez S, et al.. Nonviral cryoglobulinemic vasculitis: an updated review for clinical practice. Vessel Plus. 2023, 7:22. 10.20517\/2574-1209.2023.105","journal-title":"Vessel Plus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/art.37715","article-title":"2012 revised International Chapel Hill consensus conference nomenclature of vasculitides","volume":"65","author":"Jennette JC","year":"2013","unstructured":"Jennette JC, Falk RJ, Bacon PA, et al.. 2012 revised International Chapel Hill consensus conference nomenclature of vasculitides. Arthritis Rheum. 2013, 65:1-11. 10.1002\/art.37715","journal-title":"Arthritis Rheum"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.04.031","article-title":"ANCA-associated vasculitis: core curriculum 2020","volume":"75","author":"Geetha D","year":"2020","unstructured":"Geetha D, Jefferson JA. ANCA-associated vasculitis: core curriculum 2020. Am J Kidney Dis. 2020, 75:124-37. 10.1053\/j.ajkd.2019.04.031","journal-title":"Am J Kidney Dis"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.02.003","article-title":"IgA vasculitis (Henoch-Sh\u00f6nlein purpura) in adults: diagnostic and therapeutic aspects","volume":"14","author":"Audemard-Verger A","year":"2015","unstructured":"Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B. IgA vasculitis (Henoch-Sh\u00f6nlein purpura) in adults: diagnostic and therapeutic aspects. Autoimmun Rev. 2015, 14:579-85. 10.1016\/j.autrev.2015.02.003","journal-title":"Autoimmun Rev"},{"key":"ref14","article-title":"Drug-induced cutaneous vasculitis: a study of 466 patients","volume":"93","author":"Ortiz-Sanju\u00e1n F","year":"2014","unstructured":"Ortiz-Sanju\u00e1n F, Blanco R, Hern\u00e1ndez JL, et al.. Drug-induced cutaneous vasculitis: a study of 466 patients. Medicine (Baltimore). 2014, 93:194.","journal-title":"Medicine (Baltimore)"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e318288925c","article-title":"The spectrum of type I cryoglobulinemia vasculitis: new insights based on 64 cases","volume":"92","author":"Terrier B","year":"2013","unstructured":"Terrier B, Karras A, Kahn JE, et al.. The spectrum of type I cryoglobulinemia vasculitis: new insights based on 64 cases. Medicine (Baltimore). 2013, 92:61-8. 10.1097\/MD.0b013e318288925c","journal-title":"Medicine (Baltimore)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/508476-cryoglobulinemic-vasculitis-clinical-analysis-of-a-case-and-its-diagnostic-relevance","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T18:23:19Z","timestamp":1783275799000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/508476-cryoglobulinemic-vasculitis-clinical-analysis-of-a-case-and-its-diagnostic-relevance"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,5]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.112100","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,5]]}}}