{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:18:48Z","timestamp":1790983128788,"version":"4.1.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,8]]},"DOI":"10.7759\/cureus.112287","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T17:25:02Z","timestamp":1783531502000},"source":"Crossref","is-referenced-by-count":1,"title":["When Clopidogrel Reaches the Lung: A Case of Diffuse Interstitial Lung Disease"],"prefix":"10.7759","author":[{"given":"Emane Mengue","family":"Phalex","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darius","family":"Mbina Nzienghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laktib","family":"Nabil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najoua","family":"Mouina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwane","family":"Ouhadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2017.1315101","article-title":"The risk of bleeding with the use of antiplatelet agents for the treatment of cardiovascular disease","volume":"16","author":"Nathan AS","year":"2017","unstructured":"Nathan AS, Sen S, Yeh RW. The risk of bleeding with the use of antiplatelet agents for the treatment of cardiovascular disease. Expert Opin Drug Saf. 2017, 16:561-72. 10.1080\/14740338.2017.1315101","journal-title":"Expert Opin Drug Saf"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(96)09457-3","article-title":"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee","volume":"348","year":"1996","unstructured":"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet. 1996, 348.1329-39. 10.1016\/s0140-6736(96)09457-3","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.28394","article-title":"Clopidogrel-associated interstitial lung disease: a case report and literature review","volume":"14","author":"Abro S","year":"2022","unstructured":"Abro S, Bikeyeva V, Naqvi WA, et al.. Clopidogrel-associated interstitial lung disease: a case report and literature review. Cureus. 2022, 14:e28394. 10.7759\/cureus.28394","journal-title":"Cureus"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/jcm7100356","article-title":"Drug-induced interstitial lung disease: a systematic review","volume":"7","author":"Skeoch S","year":"2018","unstructured":"Skeoch S, Weatherley N, Swift AJ, et al.. Drug-induced interstitial lung disease: a systematic review. J Clin Med. 2018, 7:10.3390\/jcm7100356","journal-title":"J Clin Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2024.2329612","article-title":"Drug-induced interstitial lung disease: a narrative review of a clinical conundrum","volume":"18","author":"Harrison M","year":"2024","unstructured":"Harrison M, Kavanagh G, Corte TJ, Troy LK. Drug-induced interstitial lung disease: a narrative review of a clinical conundrum. Expert Rev Respir Med. 2024, 18:23-39. 10.1080\/17476348.2024.2329612","journal-title":"Expert Rev Respir Med"},{"key":"ref6","article-title":"Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels","author":"New York Heart Association Criteria Committee","year":"1994","unstructured":"New York Heart Association Criteria Committee. Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels. Martin Dolgin (ed): Little, Brown & Co, Boston, MA; 1994."},{"key":"ref7","article-title":"Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France [Article in French]","volume":"40","author":"B\u00e9gaud B","year":"1985","unstructured":"B\u00e9gaud B, Evreux JC, Jouglard J, Lagier G. Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France [Article in French]. Therapie. 1985, 40:111-8.","journal-title":"Therapie"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S319077","article-title":"Clopidogrel-induced interstitial lung disease: a case report","volume":"17","author":"An J","year":"2021","unstructured":"An J, Lee SH, Chang B. Clopidogrel-induced interstitial lung disease: a case report. Ther Clin Risk Manag. 2021, 17:711-5. 10.2147\/TCRM.S319077","journal-title":"Ther Clin Risk Manag"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154","article-title":"A method for estimating the probability of adverse drug reactions","volume":"30","author":"Naranjo CA","year":"1981","unstructured":"Naranjo CA, Busto U, Sellers EM, et al.. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981, 30:239-45. 10.1038\/clpt.1981.154","journal-title":"Clin Pharmacol Ther"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2025.102343","article-title":"A case of clopidogrel-induced organizing pneumonia evaluated by lung biopsy and confirmed by accidental re-administration","volume":"58","author":"Toyama S","year":"2025","unstructured":"Toyama S, Tanizawa K, Ouchi M, et al.. A case of clopidogrel-induced organizing pneumonia evaluated by lung biopsy and confirmed by accidental re-administration. Respir Med Case Rep. 2025, 58:102343. 10.1016\/j.rmcr.2025.102343","journal-title":"Respir Med Case Rep"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0306-3623(89)90007-4","article-title":"Effects of acetylsalicylic acid on the phagocytic function of human polymorphonuclear leukocytes in vitro","volume":"20","author":"Rodriguez AB","year":"1989","unstructured":"Rodriguez AB, Barriga C, de la Fuente M. Effects of acetylsalicylic acid on the phagocytic function of human polymorphonuclear leukocytes in vitro. Gen Pharmacol. 1989, 20:151-5. 10.1016\/0306-3623(89)90007-4","journal-title":"Gen Pharmacol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/bio.1170100204","article-title":"Ticlopidine augments luminol-dependent chemiluminescence in human neutrophils","volume":"10","author":"Bednar MM","year":"1995","unstructured":"Bednar MM, Dooley RH, Tapanes R, Lublin JC, Gross CE. Ticlopidine augments luminol-dependent chemiluminescence in human neutrophils. J Biolumin Chemilumin. 1995, 10:85-9. 10.1002\/bio.1170100204","journal-title":"J Biolumin Chemilumin"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.6.1963","article-title":"Ticlopidine-induced interstitial pulmonary disease: a case report","volume":"119","author":"Persoz CF","year":"2001","unstructured":"Persoz CF, Cornella F, Kaeser P, Rochat T. Ticlopidine-induced interstitial pulmonary disease: a case report. Chest. 2001, 119:1963-5. 10.1378\/chest.119.6.1963","journal-title":"Chest"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1253\/circj.66.773","article-title":"Interstitial pneumonia induced by ticlopidine","volume":"66","author":"Nakamura R","year":"2002","unstructured":"Nakamura R, Imamura T, Onitsuka H, et al.. Interstitial pneumonia induced by ticlopidine. Circ J. 2002, 66:773-6. 10.1253\/circj.66.773","journal-title":"Circ J"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-244564","article-title":"Clopidogrel-induced pneumonia","volume":"14","author":"Tomoda Y","year":"2021","unstructured":"Tomoda Y, Miyajima T, Nagasawa C, Awaya Y. Clopidogrel-induced pneumonia. BMJ Case Rep. 2021, 14:10.1136\/bcr-2021-244564","journal-title":"BMJ Case Rep"},{"key":"ref16","article-title":"A case of drug-induced pneumonia caused by clopidogrel [Article in Japanese]","volume":"48","author":"Tamagaki G","year":"2010","unstructured":"Tamagaki G, Matsushita H, Suzumura T, Watanabe T, Yamada S, Hirata K. A case of drug-induced pneumonia caused by clopidogrel [Article in Japanese]. Nihon Kokyuki Gakkai Zasshi. 2010, 48:404-8.","journal-title":"Nihon Kokyuki Gakkai Zasshi"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/s0828-282x(07)70788-2","article-title":"Noncardiogenic pulmonary edema associated with clopidogrel: a serious but unexpected side effect of clopidogrel","volume":"23","author":"Erdinler IC","year":"2007","unstructured":"Erdinler IC, Ucer E, Eksik A, Akyol A, Yazici S. Noncardiogenic pulmonary edema associated with clopidogrel: a serious but unexpected side effect of clopidogrel. Can J Cardiol. 2007, 23:478-80. 10.1016\/s0828-282x(07)70788-2","journal-title":"Can J Cardiol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-135-4-200108210-00028","article-title":"Severe hypersensitivity associated with clopidogrel","volume":"135","author":"Sarrot-Reynauld F","year":"2001","unstructured":"Sarrot-Reynauld F, Bouillet L, Bourrain JL. Severe hypersensitivity associated with clopidogrel. Ann Intern Med. 2001, 135:305-6. 10.7326\/0003-4819-135-4-200108210-00028","journal-title":"Ann Intern Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/509513-when-clopidogrel-reaches-the-lung-a-case-of-diffuse-interstitial-lung-disease","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T17:25:03Z","timestamp":1783531503000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/509513-when-clopidogrel-reaches-the-lung-a-case-of-diffuse-interstitial-lung-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,8]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.112287","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,8]]}}}