{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T01:13:27Z","timestamp":1783646007805,"version":"3.55.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,9]]},"DOI":"10.7759\/cureus.112365","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:24:03Z","timestamp":1783643043000},"source":"Crossref","is-referenced-by-count":0,"title":["When Safety Barriers Fail: Paracetamol-Induced Anaphylaxis Under General Anesthesia Despite Multiple Allergy Warnings"],"prefix":"10.7759","author":[{"given":"Norihiro","family":"Sakai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Michino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2020.09.021","article-title":"Emerging causes of drug-induced anaphylaxis: a review of anaphylaxis-associated reports in the FDA Adverse Event Reporting System (FAERS)","volume":"9","author":"Yu RJ","year":"2021","unstructured":"Yu RJ, Krantz MS, Phillips EJ, Stone CA Jr. Emerging causes of drug-induced anaphylaxis: a review of anaphylaxis-associated reports in the FDA Adverse Event Reporting System (FAERS). J Allergy Clin Immunol Pract. 2021, 9:819-829.e2. 10.1016\/j.jaip.2020.09.021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00315581","article-title":"Anaphylactic shock induced by paracetamol","volume":"38","author":"Van Diem L","year":"1990","unstructured":"Van Diem L, Grilliat JP. Anaphylactic shock induced by paracetamol. Eur J Clin Pharmacol. 1990, 38:389-90. 10.1007\/BF00315581","journal-title":"Eur J Clin Pharmacol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/pharmacy7010012","article-title":"Hypersensitivity reactions in serious adverse events reported for paracetamol in the EudraVigilance database, 2007\u207b2018","volume":"7","author":"Popio\u0142ek I","year":"2019","unstructured":"Popio\u0142ek I, Piotrowicz-W\u00f3jcik K, Porebski G. Hypersensitivity reactions in serious adverse events reported for paracetamol in the EudraVigilance database, 2007\u207b2018. Pharmacy (Basel). 2019, 7:12. 10.3390\/pharmacy7010012","journal-title":"Pharmacy (Basel)"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002674","article-title":"Impact of the World Health Organization Surgical Safety Checklist on patient safety","volume":"131","author":"Haugen AS","year":"2019","unstructured":"Haugen AS, Sevdalis N, S\u00f8fteland E. Impact of the World Health Organization Surgical Safety Checklist on patient safety. Anesthesiology. 2019, 131:420-5. 10.1097\/ALN.0000000000002674","journal-title":"Anesthesiology"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa0810119","article-title":"A surgical safety checklist to reduce morbidity and mortality in a global population","volume":"360","author":"Haynes AB","year":"2009","unstructured":"Haynes AB, Weiser TG, Berry WR, et al.. A surgical safety checklist to reduce morbidity and mortality in a global population. N Engl J Med. 2009, 360:491-9. 10.1056\/NEJMsa0810119","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7237.768","article-title":"Human error: models and management","volume":"320","author":"Reason J","year":"2000","unstructured":"Reason J. Human error: models and management. BMJ. 2000, 320:768-70. 10.1136\/bmj.320.7237.768","journal-title":"BMJ"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.apergo.2013.04.023","article-title":"Human factors systems approach to healthcare quality and patient safety","volume":"45","author":"Carayon P","year":"2014","unstructured":"Carayon P, Wetterneck TB, Rivera-Rodriguez AJ, Hundt AS, Hoonakker P, Holden R, Gurses AP. Human factors systems approach to healthcare quality and patient safety. Appl Ergon. 2014, 45:14-25. 10.1016\/j.apergo.2013.04.023","journal-title":"Appl Ergon"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-27099-5_3","article-title":"Patch testing methodology","author":"Lachapelle JM","year":"2020","unstructured":"Lachapelle JM, Maibach HI. Patch testing methodology. Patch Testing and Prick Testing. Lachapelle JM, Maibach HI.  (ed): Springer, Cham; 2020. 39-84. 10.1007\/978-3-030-27099-5_3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2013.02.036","article-title":"Unexpected death: anaphylactic intraoperative death due to thymoglobulin carbohydrate excipient","volume":"228","author":"Roncati L","year":"2013","unstructured":"Roncati L, Barbolini G, Scacchetti AT, Busani S, Maiorana A. Unexpected death: anaphylactic intraoperative death due to thymoglobulin carbohydrate excipient. Forensic Sci Int. 2013, 228:e28-32. 10.1016\/j.forsciint.2013.02.036","journal-title":"Forensic Sci Int"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X1504300617","article-title":"Anaphylaxis following intravenous paracetamol: the problem is the solution","volume":"43","author":"Jain SS","year":"2015","unstructured":"Jain SS, Green S, Rose M. Anaphylaxis following intravenous paracetamol: the problem is the solution. Anaesth Intensive Care. 2015, 43:779-81. 10.1177\/0310057X1504300617","journal-title":"Anaesth Intensive Care"},{"key":"ref11","article-title":"The Checklist Manifesto: How to Get Things Right","author":"Gawande A","year":"2009","unstructured":"Gawande A. The Checklist Manifesto: How to Get Things Right. Picador, New York City, NY; 2009."}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/324868-when-safety-barriers-fail-paracetamol-induced-anaphylaxis-under-general-anesthesia-despite-multiple-allergy-warnings","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:24:04Z","timestamp":1783643044000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/324868-when-safety-barriers-fail-paracetamol-induced-anaphylaxis-under-general-anesthesia-despite-multiple-allergy-warnings"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,9]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.112365","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,9]]}}}