{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T07:04:26Z","timestamp":1784012666264,"version":"3.55.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,13]]},"DOI":"10.7759\/cureus.112625","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T06:13:34Z","timestamp":1784009614000},"source":"Crossref","is-referenced-by-count":0,"title":["Occult Metastatic Prostate Carcinoma Presenting With Decompensated Heart Failure and Bicytopenia"],"prefix":"10.7759","author":[{"given":"Ravi","family":"Krishnegowda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinidhi","family":"Rao V R","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramangouda","family":"Malipatil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2022.02.010","article-title":"2022 ACC\/AHA\/HFSA guideline for the management of heart failure","volume":"28","year":"2022","unstructured":"2022 ACC\/AHA\/HFSA guideline for the management of heart failure. J Card Fail. 2022, 28.e1-167. 10.1016\/j.cardfail.2022.02.010","journal-title":"J Card Fail"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13699","article-title":"Thrombocytopenia in intensive care unit patients: a scoping review","volume":"65","author":"Jonsson AB","year":"2021","unstructured":"Jonsson AB, Ryg\u00e5rd SL, Hildebrandt T, Perner A, M\u00f8ller MH, Russell L. Thrombocytopenia in intensive care unit patients: a scoping review. Acta Anaesthesiol Scand. 2021, 65:2-14. 10.1111\/aas.13699","journal-title":"Acta Anaesthesiol Scand"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra030831","article-title":"Mechanisms of bone metastasis","volume":"350","author":"Roodman GD","year":"2004","unstructured":"Roodman GD. Mechanisms of bone metastasis. N Engl J Med. 2004, 350:1655-64. 10.1056\/NEJMra030831","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1528","article-title":"Osteoblasts in prostate cancer metastasis to bone","volume":"5","author":"Logothetis CJ","year":"2005","unstructured":"Logothetis CJ, Lin SH. Osteoblasts in prostate cancer metastasis to bone. Nat Rev Cancer. 2005, 5:21-8. 10.1038\/nrc1528","journal-title":"Nat Rev Cancer"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1053\/hp.2000.6698","article-title":"Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients","volume":"31","author":"Bubendorf L","year":"2000","unstructured":"Bubendorf L, Sch\u00f6pfer A, Wagner U, et al.. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol. 2000, 31:578-83. 10.1053\/hp.2000.6698","journal-title":"Hum Pathol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2013.08.003","article-title":"The CARE guidelines: consensus-based clinical case report guideline development","volume":"67","author":"Gagnier JJ","year":"2014","unstructured":"Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D. The CARE guidelines: consensus-based clinical case report guideline development. J Clin Epidemiol. 2014, 67:46-51. 10.1016\/j.jclinepi.2013.08.003","journal-title":"J Clin Epidemiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2025.03.038","article-title":"Updated definition and scoring of disseminated intravascular coagulation in 2025: communication from the ISTH SSC Subcommittee on Disseminated Intravascular Coagulation","volume":"23","author":"Iba T","year":"2025","unstructured":"Iba T, Levy JH, Maier CL, et al.. Updated definition and scoring of disseminated intravascular coagulation in 2025: communication from the ISTH SSC Subcommittee on Disseminated Intravascular Coagulation. J Thromb Haemost. 2025, 23:2356-62. 10.1016\/j.jtha.2025.03.038","journal-title":"J Thromb Haemost"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2007.02313.x","article-title":"The scoring system of the Scientific and Standardisation Committee on Disseminated Intravascular Coagulation of the International Society on Thrombosis and Haemostasis: a 5-year overview","volume":"5","author":"Toh CH","year":"2007","unstructured":"Toh CH, Hoots WK. The scoring system of the Scientific and Standardisation Committee on Disseminated Intravascular Coagulation of the International Society on Thrombosis and Haemostasis: a 5-year overview. J Thromb Haemost. 2007, 5:604-6. 10.1111\/j.1538-7836.2007.02313.x","journal-title":"J Thromb Haemost"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e6cbf3","article-title":"NKX3.1 as a marker of prostatic origin in metastatic tumors","volume":"34","author":"Gurel B","year":"2010","unstructured":"Gurel B, Ali TZ, Montgomery EA, et al.. NKX3.1 as a marker of prostatic origin in metastatic tumors. Am J Surg Pathol. 2010, 34:1097-105. 10.1097\/PAS.0b013e3181e6cbf3","journal-title":"Am J Surg Pathol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18061151","article-title":"Sensitivity of HOXB13 as a diagnostic immunohistochemical marker of prostatic origin in prostate cancer metastases: comparison to PSA, prostein, androgen receptor, ERG, NKX3.1, PSAP, and PSMA","volume":"18","author":"Kristiansen I","year":"2017","unstructured":"Kristiansen I, Stephan C, Jung K, Dietel M, Rieger A, Tolkach Y, Kristiansen G. Sensitivity of HOXB13 as a diagnostic immunohistochemical marker of prostatic origin in prostate cancer metastases: comparison to PSA, prostein, androgen receptor, ERG, NKX3.1, PSAP, and PSMA. Int J Mol Sci. 2017, 18:1151. 10.3390\/ijms18061151","journal-title":"Int J Mol Sci"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2024.03.027","article-title":"EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines on prostate cancer-2024 update. Part I: screening, diagnosis, and local treatment with curative intent","volume":"86","author":"Cornford P","year":"2024","unstructured":"Cornford P, van den Bergh RC, Briers E, et al.. EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines on prostate cancer-2024 update. Part I: screening, diagnosis, and local treatment with curative intent. Eur Urol. 2024, 86:148-63. 10.1016\/j.eururo.2024.03.027","journal-title":"Eur Urol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2024.04.010","article-title":"EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines on prostate cancer. Part II-2024 update: treatment of relapsing and metastatic prostate cancer","volume":"86","author":"Tilki D","year":"2024","unstructured":"Tilki D, van den Bergh RC, Briers E, et al.. EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines on prostate cancer. Part II-2024 update: treatment of relapsing and metastatic prostate cancer. Eur Urol. 2024, 86:164-82. 10.1016\/j.eururo.2024.04.010","journal-title":"Eur Urol"},{"key":"ref13","unstructured":"NCCN Guidelines. (2026). Accessed. 2026: https:\/\/www.nccn.org\/guidelines\/guidelines-detail?category=1&id=1459."},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503747","article-title":"Chemohormonal therapy in metastatic hormone-sensitive prostate cancer","volume":"373","author":"Sweeney CJ","year":"2015","unstructured":"Sweeney CJ, Chen YH, Carducci M, et al.. Chemohormonal therapy in metastatic hormone-sensitive prostate cancer. N Engl J Med. 2015, 373:737-46. 10.1056\/NEJMoa1503747","journal-title":"N Engl J Med"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704174","article-title":"Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer","volume":"377","author":"Fizazi K","year":"2017","unstructured":"Fizazi K, Tran N, Fein L, et al.. Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer. N Engl J Med. 2017, 377:352-60. 10.1056\/NEJMoa1704174","journal-title":"N Engl J Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.07600.x","article-title":"Guidelines for the diagnosis and management of disseminated intravascular coagulation","volume":"145","author":"Levi M","year":"2009","unstructured":"Levi M, Toh CH, Thachil J, Watson HG. Guidelines for the diagnosis and management of disseminated intravascular coagulation. Br J Haematol. 2009, 145:24-33. 10.1111\/j.1365-2141.2009.07600.x","journal-title":"Br J Haematol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0270956","article-title":"Bone marrow involvement in patients with metastatic castration sensitive prostate cancer","volume":"17","author":"Shahait M","year":"2022","unstructured":"Shahait M, Abu-Hijlih R, Salamat A, Abou Heidar N, Sharaf B, Abuhijla F, Salah S. Bone marrow involvement in patients with metastatic castration sensitive prostate cancer. PLoS One. 2022, 17:e0270956. 10.1371\/journal.pone.0270956","journal-title":"PLoS One"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.3320","article-title":"Clinicopathological characteristics of localized prostate cancer in younger men aged\u00a0\u2264\u00a050\u00a0years treated with radical prostatectomy in the PSA era: a systematic review and meta-analysis","volume":"9","author":"Zheng Y","year":"2020","unstructured":"Zheng Y, Lin SX, Wu S, et al.. Clinicopathological characteristics of localized prostate cancer in younger men aged\u00a0\u2264\u00a050\u00a0years treated with radical prostatectomy in the PSA era: a systematic review and meta-analysis. Cancer Med. 2020, 9:6473-84. 10.1002\/cam4.3320","journal-title":"Cancer Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/501402-occult-metastatic-prostate-carcinoma-presenting-with-decompensated-heart-failure-and-bicytopenia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T06:13:35Z","timestamp":1784009615000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/501402-occult-metastatic-prostate-carcinoma-presenting-with-decompensated-heart-failure-and-bicytopenia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.112625","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,13]]}}}