{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T07:04:47Z","timestamp":1784012687990,"version":"3.55.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,13]]},"DOI":"10.7759\/cureus.112626","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T06:18:11Z","timestamp":1784009891000},"source":"Crossref","is-referenced-by-count":0,"title":["Current Tobacco\/Nicotine Use and Pelvic Pain and Urgency\/Frequency (PUF)-Defined Urinary Symptom Burden Among Lebanese University-Aged Adults: A Cross-Sectional Study"],"prefix":"10.7759","author":[{"given":"Aoumar G","family":"Chamma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Saliba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Nasr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Chamma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"World Health Organization. tobacco and nicotine. (2026). Accessed: July 4, 2026: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/tobacco."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2003.00413.x","article-title":"Tobacco use by university students, Lebanon, 2001","volume":"98","author":"Tamim H","year":"2003","unstructured":"Tamim H, Terro A, Kassem H, Ghazi A, Khamis TA, Hay MM, Musharrafieh U. Tobacco use by university students, Lebanon, 2001. Addiction. 2003, 98:933-9. 10.1046\/j.1360-0443.2003.00413.x","journal-title":"Addiction"},{"key":"ref3","article-title":"Smoking: Its impact on urologic health","volume":"17","author":"Mobley D","year":"2015","unstructured":"Mobley D, Baum N. Smoking: Its impact on urologic health. Rev Urol. 2015, 17:220-5.","journal-title":"Rev Urol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.04.097","article-title":"Evidence of the impact of diet, fluid intake, caffeine, alcohol and tobacco on lower urinary tract symptoms: a systematic review","volume":"198","author":"Bradley CS","year":"2017","unstructured":"Bradley CS, Erickson BA, Messersmith EE, et al.. Evidence of the impact of diet, fluid intake, caffeine, alcohol and tobacco on lower urinary tract symptoms: a systematic review. J Urol. 2017, 198:1010-20. 10.1016\/j.juro.2017.04.097","journal-title":"J Urol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10052","article-title":"The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society","volume":"21","author":"Abrams P","year":"2002","unstructured":"Abrams P, Cardozo L, Fall M, et al.. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn. 2002, 21:167-78. 10.1002\/nau.10052","journal-title":"Neurourol Urodyn"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.9734\/BJMMR\/2016\/26472","article-title":"Prevalence of lower urinary tract symptoms in apparently healthy young Nigerian women","volume":"16","author":"Oyelade B","year":"2016","unstructured":"Oyelade B, Jemilohun A. Prevalence of lower urinary tract symptoms in apparently healthy young Nigerian women. Br J Med Med Res. 2016, 16:1-7. 10.9734\/BJMMR\/2016\/26472","journal-title":"Br J Med Med Res"},{"key":"ref7","article-title":"Prevalence, risk factors and bother associated with lower urinary tract symptoms among young adults in Al-Qassim, Saudi Arabia","volume":"7","author":"Alzammam AM","year":"2017","unstructured":"Alzammam AM, Almurais RA, Alahmad RM, et al.. Prevalence, risk factors and bother associated with lower urinary tract symptoms among young adults in Al-Qassim, Saudi Arabia. Ann Med Health Sci Res. 2017, 7:418-27.","journal-title":"Ann Med Health Sci Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-013-2057-3","article-title":"Interstitial cystitis\/bladder pain syndrome: diagnosis and management","volume":"24","author":"Offiah I","year":"2013","unstructured":"Offiah I, McMahon SB, O'Reilly BA. Interstitial cystitis\/bladder pain syndrome: diagnosis and management. Int Urogynecol J. 2013, 24:1243-56. 10.1007\/s00192-013-2057-3","journal-title":"Int Urogynecol J"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.03.064","article-title":"AUA guideline for the diagnosis and treatment of interstitial cystitis\/bladder pain syndrome","volume":"185","author":"Hanno PM","year":"2011","unstructured":"Hanno PM, Burks DA, Clemens JQ, et al.. AUA guideline for the diagnosis and treatment of interstitial cystitis\/bladder pain syndrome. J Urol. 2011, 185:2162-70. 10.1016\/j.juro.2011.03.064","journal-title":"J Urol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1080\/15360288.2018.1476433","article-title":"Interstitial cystitis: an update on the disease process and treatment","volume":"32","author":"Daniels AM","year":"2018","unstructured":"Daniels AM, Schulte AR, Herndon CM. Interstitial cystitis: an update on the disease process and treatment. J Pain Palliat Care Pharmacother. 2018, 32:49-58. 10.1080\/15360288.2018.1476433","journal-title":"J Pain Palliat Care Pharmacother"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s0090-4295(02)01829-0","article-title":"Increased prevalence of interstitial cystitis: previously unrecognized cases identified using a new symptom questionnaire and intravesical potassium sensitivity","volume":"60","author":"Parsons CL","year":"2002","unstructured":"Parsons CL, Dell J, Stanford EJ, et al.. Increased prevalence of interstitial cystitis: previously unrecognized cases identified using a new symptom questionnaire and intravesical potassium sensitivity. Urology. 2002, 60:573-8. 10.1016\/s0090-4295(02)01829-0","journal-title":"Urology"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.03.035","article-title":"Efficiency of questionnaires used to screen for interstitial cystitis","volume":"176","author":"Kushner L","year":"2006","unstructured":"Kushner L, Moldwin RM. Efficiency of questionnaires used to screen for interstitial cystitis. J Urol. 2006, 176:587-92. 10.1016\/j.juro.2006.03.035","journal-title":"J Urol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13177","article-title":"Cigarette smoke-induced urothelial cell damage: potential role of platelet-activating factor","volume":"5","author":"Kispert SE","year":"2017","unstructured":"Kispert SE, Marentette J, Campian EC, Isbell TS, Kuenzel H, McHowat J. Cigarette smoke-induced urothelial cell damage: potential role of platelet-activating factor. Physiol Rep. 2017, 5:e13177. 10.14814\/phy2.13177","journal-title":"Physiol Rep"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.88.5.2149","article-title":"Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults","volume":"88","author":"Celermajer DS","year":"1993","unstructured":"Celermajer DS, Sorensen KE, Georgakopoulos D, Bull C, Thomas O, Robinson J, Deanfield JE. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation. 1993, 88:2149-55. 10.1161\/01.cir.88.5.2149","journal-title":"Circulation"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.12.047","article-title":"The pathophysiology of cigarette smoking and cardiovascular disease: an update","volume":"43","author":"Ambrose JA","year":"2004","unstructured":"Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol. 2004, 43:1731-7. 10.1016\/j.jacc.2003.12.047","journal-title":"J Am Coll Cardiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/1557988315601724","article-title":"Impact of cigarette smoking on serum pro- and anti-inflammatory cytokines and growth factors","volume":"11","author":"Daloee MH","year":"2017","unstructured":"Daloee MH, Avan A, Mirhafez SR, et al.. Impact of cigarette smoking on serum pro- and anti-inflammatory cytokines and growth factors. Am J Mens Health. 2017, 11:1169-73. 10.1177\/1557988315601724","journal-title":"Am J Mens Health"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2010.02.011","article-title":"The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses","volume":"92","author":"Yost CC","year":"2010","unstructured":"Yost CC, Weyrich AS, Zimmerman GA. The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses. Biochimie. 2010, 92:692-7. 10.1016\/j.biochi.2010.02.011","journal-title":"Biochimie"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/s0029-7844(00)00808-5","article-title":"Dietary caffeine intake and the risk for detrusor instability: a case-control study","volume":"96","author":"Arya LA","year":"2000","unstructured":"Arya LA, Myers DL, Jackson ND. Dietary caffeine intake and the risk for detrusor instability: a case-control study. Obstet Gynecol. 2000, 96:85-9. 10.1016\/s0029-7844(00)00808-5","journal-title":"Obstet Gynecol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7796.75862","article-title":"Effect of caffeine on bladder function in patients with overactive bladder symptoms","volume":"3","author":"Lohsiriwat S","year":"2011","unstructured":"Lohsiriwat S, Hirunsai M, Chaiyaprasithi B. Effect of caffeine on bladder function in patients with overactive bladder symptoms. Urol Ann. 2011, 3:14-8. 10.4103\/0974-7796.75862","journal-title":"Urol Ann"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.03.020","article-title":"Effect of comestibles on symptoms of interstitial cystitis","volume":"178","author":"Shorter B","year":"2007","unstructured":"Shorter B, Lesser M, Moldwin RM, Kushner L. Effect of comestibles on symptoms of interstitial cystitis. J Urol. 2007, 178:145-52. 10.1016\/j.juro.2007.03.020","journal-title":"J Urol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.541782.AD","article-title":"Strengthening the reporting of OBservational studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"335","author":"von Elm E","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. Strengthening the reporting of OBservational studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. BMJ. 2007, 335:806-8. 10.1136\/bmj.39335.541782.AD","journal-title":"BMJ"},{"key":"ref22","unstructured":"Tobacco questions for surveys (TQS). a subset of key questions from the Global Adult Tobacco Survey (GATS) 2nd edition. (2011). Accessed: July 13, 2026: https:\/\/www.who.int\/publications\/i\/item\/9789241500951."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-3-21","article-title":"Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio","volume":"3","author":"Barros AJ","year":"2003","unstructured":"Barros AJ, Hirakata VN. Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. BMC Med Res Methodol. 2003, 3:21. 10.1186\/1471-2288-3-21","journal-title":"BMC Med Res Methodol"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.22037\/uj.v12i6.2981","article-title":"Smoking and lower urinary tract symptoms","volume":"12","author":"Bolat M","year":"2015","unstructured":"Bolat M, Akdeniz E, Ozkaya S, et al.. Smoking and lower urinary tract symptoms. Urol J. 2015, 12:2447-53. 10.22037\/uj.v12i6.2981","journal-title":"Urol J"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-77223-7","article-title":"The impact of smoking on male lower urinary tract symptoms (LUTS)","volume":"10","author":"Kawahara T","year":"2020","unstructured":"Kawahara T, Ito H, Uemura H. The impact of smoking on male lower urinary tract symptoms (LUTS). Sci Rep. 2020, 10:20212. 10.1038\/s41598-020-77223-7","journal-title":"Sci Rep"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.12.072","article-title":"Influence of smoking, coffee, and tea consumption on bladder pain syndrome in female twins","volume":"77","author":"Tettamanti G","year":"2011","unstructured":"Tettamanti G, Nyman-Iliadou A, Pedersen NL, Bellocco R, Milsom I, Altman D. Influence of smoking, coffee, and tea consumption on bladder pain syndrome in female twins. Urology. 2011, 77:1313-7. 10.1016\/j.urology.2010.12.072","journal-title":"Urology"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1136\/tobaccocontrol-2014-051903","article-title":"The global epidemiology of waterpipe smoking","volume":"24","author":"Maziak W","year":"2015","unstructured":"Maziak W, Taleb ZB, Bahelah R, Islam F, Jaber R, Auf R, Salloum RG. The global epidemiology of waterpipe smoking. Tob Control. 2015, 24:i3-12. 10.1136\/tobaccocontrol-2014-051903","journal-title":"Tob Control"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/432404-current-tobacconicotine-use-and-pelvic-pain-and-urgencyfrequency-puf-defined-urinary-symptom-burden-among-lebanese-university-aged-adults-a-cross-sectional-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T06:18:13Z","timestamp":1784009893000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/432404-current-tobacconicotine-use-and-pelvic-pain-and-urgencyfrequency-puf-defined-urinary-symptom-burden-among-lebanese-university-aged-adults-a-cross-sectional-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":27,"URL":"https:\/\/doi.org\/10.7759\/cureus.112626","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,13]]}}}