{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:04:30Z","timestamp":1784307870246,"version":"3.55.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,17]]},"DOI":"10.7759\/cureus.112867","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:18:16Z","timestamp":1784305096000},"source":"Crossref","is-referenced-by-count":0,"title":["Necrotizing Otitis Externa Due to Scedosporium sp.: A Case Report"],"prefix":"10.7759","author":[{"given":"Chaimaa","family":"Boujloud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakaria","family":"Essamhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adil","family":"Maleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azzedine","family":"Lachkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aziza","family":"Hami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24440","article-title":"Central skull base osteomyelitis: an emerging clinical entity","volume":"124","author":"Johnson AK","year":"2014","unstructured":"Johnson AK, Batra PS. Central skull base osteomyelitis: an emerging clinical entity. Laryngoscope. 2014, 124:1083-7. 10.1002\/lary.24440","journal-title":"Laryngoscope"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mmcr.2016.04.002","article-title":"Scedosporium apiospermum as a rare cause of central skull base osteomyelitis","volume":"11","author":"Jalava-Karvinen P","year":"2016","unstructured":"Jalava-Karvinen P, Nyman M, Gardberg M, Harju I, Hohenthal U, Oksi J. Scedosporium apiospermum as a rare cause of central skull base osteomyelitis. Med Mycol Case Rep. 2016, 11:28-30. 10.1016\/j.mmcr.2016.04.002","journal-title":"Med Mycol Case Rep"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.mmcr.2016.11.001","article-title":"Rapid development of a mycotic aneurysm of the intracranial artery secondary to Scedosporium apiospermum sinusitis","volume":"14","author":"Ogawa Y","year":"2016","unstructured":"Ogawa Y, Sato M, Tashiro M, et al.. Rapid development of a mycotic aneurysm of the intracranial artery secondary to Scedosporium apiospermum sinusitis. Med Mycol Case Rep. 2016, 14:30-2. 10.1016\/j.mmcr.2016.11.001","journal-title":"Med Mycol Case Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1080\/13693780600752507","article-title":"Scedosporium apiospermum: changing clinical spectrum of a therapy-refractory opportunist","volume":"44","author":"Guarro J","year":"2006","unstructured":"Guarro J, Kantarcioglu AS, Horr\u00e9 R, Rodriguez-Tudela JL, Cuenca Estrella M, Berenguer J, de Hoog GS. Scedosporium apiospermum: changing clinical spectrum of a therapy-refractory opportunist. Med Mycol. 2006, 44:295-327. 10.1080\/13693780600752507","journal-title":"Med Mycol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01122-07","article-title":"Molecular and phenotypic data supporting distinct species statuses for Scedosporium apiospermum and Pseudallescheria boydii and the proposed new species Scedosporium dehoogii","volume":"46","author":"Gilgado F","year":"2008","unstructured":"Gilgado F, Cano J, Gen\u00e9 J, Sutton DA, Guarro J. Molecular and phenotypic data supporting distinct species statuses for Scedosporium apiospermum and Pseudallescheria boydii and the proposed new species Scedosporium dehoogii. J Clin Microbiol. 2008, 46:766-71. 10.1128\/JCM.01122-07","journal-title":"J Clin Microbiol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.resinv.2013.07.001","article-title":"Scedosporium aurantiacum brain abscess after near-drowning in a survivor of a tsunami in Japan","volume":"51","author":"Nakamura Y","year":"2013","unstructured":"Nakamura Y, Suzuki N, Nakajima Y, et al.. Scedosporium aurantiacum brain abscess after near-drowning in a survivor of a tsunami in Japan. Respir Investig. 2013, 51:207-11. 10.1016\/j.resinv.2013.07.001","journal-title":"Respir Investig"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00039-07","article-title":"Infections caused by Scedosporium spp","volume":"21","author":"Cortez KJ","year":"2008","unstructured":"Cortez KJ, Roilides E, Quiroz-Telles F, et al.. Infections caused by Scedosporium spp. Clin Microbiol Rev. 2008, 21:157-97. 10.1128\/CMR.00039-07","journal-title":"Clin Microbiol Rev"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s100960050011","article-title":"Clinical significance of Scedosporium apiospermum in patients with cystic fibrosis","volume":"19","author":"Cimon B","year":"2000","unstructured":"Cimon B, Carr\u00e8re J, Vinatier JF, Chazalette JP, Chabasse D, Bouchara JP. Clinical significance of Scedosporium apiospermum in patients with cystic fibrosis. Eur J Clin Microbiol Infect Dis. 2000, 19:53-6. 10.1007\/s100960050011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myx113","article-title":"Scedosporium and Lomentospora: an updated overview of underrated opportunists","volume":"56","author":"Ramirez-Garcia A","year":"2018","unstructured":"Ramirez-Garcia A, Pellon A, Rementeria A, et al.. Scedosporium and Lomentospora: an updated overview of underrated opportunists. Med Mycol. 2018, 56:102-25. 10.1093\/mmy\/myx113","journal-title":"Med Mycol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.841286","article-title":"Performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Scedosporium, Acremonium-like, Scopulariopsis, and Microascus species","volume":"13","author":"Wei L","year":"2022","unstructured":"Wei L, Shao J, Song Y, Wan Z, Yao L, Wang H, Yu J. Performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Scedosporium, Acremonium-like, Scopulariopsis, and Microascus species. Front Microbiol. 2022, 13:841286. 10.3389\/fmicb.2022.841286","journal-title":"Front Microbiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.1.62-68.2002","article-title":"In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates","volume":"46","author":"Meletiadis J","year":"2002","unstructured":"Meletiadis J, Meis JF, Mouton JW, Rodriquez-Tudela JL, Donnelly JP, Verweij PE. In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates. Antimicrob Agents Chemother. 2002, 46:62-8. 10.1128\/AAC.46.1.62-68.2002","journal-title":"Antimicrob Agents Chemother"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2020.115007","article-title":"In vitro activity of isavuconazole versus opportunistic filamentous fungal pathogens from the SENTRY Antifungal Surveillance Program, 2017-2018","volume":"97","author":"Messer SA","year":"2020","unstructured":"Messer SA, Carvalhaes CG, Castanheira M, Pfaller MA. In vitro activity of isavuconazole versus opportunistic filamentous fungal pathogens from the SENTRY Antifungal Surveillance Program, 2017-2018. Diagn Microbiol Infect Dis. 2020, 97:115007. 10.1016\/j.diagmicrobio.2020.115007","journal-title":"Diagn Microbiol Infect Dis"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1080\/1040841X.2018.1514366","article-title":"Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope(\u00ae)","volume":"45","author":"Seidel D","year":"2019","unstructured":"Seidel D, Mei\u00dfner A, Lackner M, et al.. Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope(\u00ae). Crit Rev Microbiol. 2019, 45:1-21. 10.1080\/1040841X.2018.1514366","journal-title":"Crit Rev Microbiol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.mmcr.2016.04.005","article-title":"Scedosporium apiospermum infections and the role of combination antifungal therapy and GM-CSF: a case report and review of the literature","volume":"11","author":"Goldman C","year":"2016","unstructured":"Goldman C, Akiyama MJ, Torres J, Louie E, Meehan SA. Scedosporium apiospermum infections and the role of combination antifungal therapy and GM-CSF: a case report and review of the literature. Med Mycol Case Rep. 2016, 11:40-3. 10.1016\/j.mmcr.2016.04.005","journal-title":"Med Mycol Case Rep"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14580","article-title":"Salvage therapy with topical posaconazole in lung transplant recipients with invasive Scedosporium infection","volume":"18","author":"Sol\u00e9 A","year":"2018","unstructured":"Sol\u00e9 A, Garc\u00eda-Robles AA, Jord\u00e1 C, et al.. Salvage therapy with topical posaconazole in lung transplant recipients with invasive Scedosporium infection. Am J Transplant. 2018, 18:504-9. 10.1111\/ajt.14580","journal-title":"Am J Transplant"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111000415","article-title":"Fungal malignant otitis externa due to Scedosporium apiospermum","volume":"110","author":"Yao M","year":"2001","unstructured":"Yao M, Messner AH. Fungal malignant otitis externa due to Scedosporium apiospermum. Ann Otol Rhinol Laryngol. 2001, 110:377-80. 10.1177\/000348940111000415","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2004.02.013","article-title":"Otitis caused by Scedosporium apiospermum in an immunocompetent child","volume":"68","author":"Bhally HS","year":"2004","unstructured":"Bhally HS, Shields C, Lin SY, Merz WG. Otitis caused by Scedosporium apiospermum in an immunocompetent child. Int J Pediatr Otorhinolaryngol. 2004, 68:975-8. 10.1016\/j.ijporl.2004.02.013","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0255-0857(21)02359-8","article-title":"Brain abscess due to Scedosporium apiospermum in a non immunocompromised child","volume":"24","author":"Acharya A","year":"2006","unstructured":"Acharya A, Ghimire A, Khanal B, Bhattacharya S, Kumari N, Kanungo R. Brain abscess due to Scedosporium apiospermum in a non immunocompromised child. Indian J Med Microbiol. 2006, 24:231-2. 10.1016\/S0255-0857(21)02359-8","journal-title":"Indian J Med Microbiol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2006.08.017","article-title":"Scedosporium apiospermum otomycosis","volume":"28","author":"Baumgartner BJ","year":"2007","unstructured":"Baumgartner BJ, Rakita RM, Backous DD. Scedosporium apiospermum otomycosis. Am J Otolaryngol. 2007, 28:254-6. 10.1016\/j.amjoto.2006.08.017","journal-title":"Am J Otolaryngol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2007.03.003","article-title":"Eumycetoma presenting as a cerebellopontine angle mass lesion","volume":"109","author":"Sai Kiran NA","year":"2007","unstructured":"Sai Kiran NA, Kasliwal MK, Suri A, et al.. Eumycetoma presenting as a cerebellopontine angle mass lesion. Clin Neurol Neurosurg. 2007, 109:516-9. 10.1016\/j.clineuro.2007.03.003","journal-title":"Clin Neurol Neurosurg"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2007.10.011","article-title":"Efficacy of voriconazole for Scedosporium apiospermum skull base osteomyelitis: case report and literature review","volume":"31","author":"Vasoo S","year":"2008","unstructured":"Vasoo S, Yeo SB, Lim PL, Ang BS, Lye DC. Efficacy of voriconazole for Scedosporium apiospermum skull base osteomyelitis: case report and literature review. Int J Antimicrob Agents. 2008, 31:184-5. 10.1016\/j.ijantimicag.2007.10.011","journal-title":"Int J Antimicrob Agents"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60699-1","article-title":"Fatal consequences of an ear infection","volume":"373","author":"Stalpers XL","year":"2009","unstructured":"Stalpers XL, Smink-Bol M, Verweij PE, Wesseling P, van Dijk GW. Fatal consequences of an ear infection. Lancet. 2009, 373:1658. 10.1016\/S0140-6736(09)60699-1","journal-title":"Lancet"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2009.01.005","article-title":"A case report of an otitis externa with osteolysis caused by Scedosporium apiospermum","volume":"2","author":"Bienvenu AL","year":"2009","unstructured":"Bienvenu AL, Rigollet L, Martins-Carvalho C, Truy E, Picot S. A case report of an otitis externa with osteolysis caused by Scedosporium apiospermum. Surg Case Rep. 2009, 2:129-33. 10.1016\/j.mycmed.2009.01.005","journal-title":"Surg Case Rep"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2015.07.045","article-title":"Scedosporium apiospermum causing otomycosis in an immunocompetent child with tympanostomy tubes: management of this rare entity","volume":"79","author":"Salamat AA","year":"2015","unstructured":"Salamat AA, Archer C, Basarab A, et al.. Scedosporium apiospermum causing otomycosis in an immunocompetent child with tympanostomy tubes: management of this rare entity. Int J Pediatr Otorhinolaryngol. 2015, 79:1785-7. 10.1016\/j.ijporl.2015.07.045","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000651","article-title":"A rare case of Scedosporium otitis in an immunocompetent child with tympanostomy tubes","volume":"34","author":"Koay WL","year":"2015","unstructured":"Koay WL, Johnson CB, Patel J, Aigbivbalu LO. A rare case of Scedosporium otitis in an immunocompetent child with tympanostomy tubes. Pediatr Infect Dis J. 2015, 34:799. 10.1097\/INF.0000000000000651","journal-title":"Pediatr Infect Dis J"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001291","article-title":"Scedosporium prolificans otitis externa","volume":"35","author":"Wen SC","year":"2016","unstructured":"Wen SC, Phillips D, Gwee A. Scedosporium prolificans otitis externa. Pediatr Infect Dis J. 2016, 35:1277. 10.1097\/INF.0000000000001291","journal-title":"Pediatr Infect Dis J"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.riam.2019.04.003","article-title":"Otomastoiditis due to Scedosporium apiospermum. Hallucinations as an adverse reaction to voriconazole (Article in Spanish)","volume":"36","author":"Fuster-Escriv\u00e1 B","year":"2019","unstructured":"Fuster-Escriv\u00e1 B, Chanz\u00e1-Avi\u00f1\u00f3 M, Concepci\u00f3n Gimeno-Cardona. Otomastoiditis due to Scedosporium apiospermum. Hallucinations as an adverse reaction to voriconazole (Article in Spanish). Rev Iberoam Micol. 2019, 36:165-6. 10.1016\/j.riam.2019.04.003","journal-title":"Rev Iberoam Micol"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.45838","article-title":"Rare cause of skull base osteomyelitis: a challenging diagnosis and management with a literature review","volume":"15","author":"Hussain SZ","year":"2023","unstructured":"Hussain SZ, Haq II, Arshad Z, Ekunola A, Das S. Rare cause of skull base osteomyelitis: a challenging diagnosis and management with a literature review. Cureus. 2023, 15:45838. 10.7759\/cureus.45838","journal-title":"Cureus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/503544-necrotizing-otitis-externa-due-to-scedosporium-sp-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:18:16Z","timestamp":1784305096000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/503544-necrotizing-otitis-externa-due-to-scedosporium-sp-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,17]]},"references-count":28,"URL":"https:\/\/doi.org\/10.7759\/cureus.112867","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,17]]}}}