{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:38:31Z","timestamp":1786117111931,"version":"build-2736575974"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,6]]},"DOI":"10.7759\/cureus.114059","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T13:20:36Z","timestamp":1786022436000},"source":"Crossref","is-referenced-by-count":0,"title":["Radiation Monotherapy for Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type: A Case Report"],"prefix":"10.7759","author":[{"given":"Maudood","family":"Rana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Jamison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Jeffrey","family":"Medeiros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Taher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haleigh","family":"Mistry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.70053","article-title":"Primary cutaneous B-cell lymphomas: an updated portrait of classification, biology, and clinical management","volume":"116","author":"Bernardelli A","year":"2026","unstructured":"Bernardelli A, Carazzai E, Bugnotto B, Bellinato F, Krampera M, Visco C. Primary cutaneous B-cell lymphomas: an updated portrait of classification, biology, and clinical management. Eur J Haematol. 2026, 116:116-28. 10.1111\/ejh.70053","journal-title":"Eur J Haematol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.8651","article-title":"Primary cutaneous diffuse large B-cell lymphoma, leg type: A case report","volume":"12","author":"Al-Obaidi A","year":"2020","unstructured":"Al-Obaidi A, Parker NA, Choucair K, Lalich D, Truong P. Primary cutaneous diffuse large B-cell lymphoma, leg type: A case report. Cureus. 2020, 12:e8651. 10.7759\/cureus.8651","journal-title":"Cureus"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2018.08.006","article-title":"Cutaneous B-cell lymphoma","volume":"33","author":"Goyal A","year":"2019","unstructured":"Goyal A, LeBlanc RE, Carter JB. Cutaneous B-cell lymphoma. Hematol Oncol Clin North Am. 2019, 33:149-61. 10.1016\/j.hoc.2018.08.006","journal-title":"Hematol Oncol Clin North Am"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17071202","article-title":"Unveiling primary cutaneous B-cell lymphomas: new insights into diagnosis and treatment strategies","volume":"17","author":"Barbati ZR","year":"2025","unstructured":"Barbati ZR, Charli-Joseph Y. Unveiling primary cutaneous B-cell lymphomas: new insights into diagnosis and treatment strategies. Cancers (Basel). 2025, 17:1202. 10.3390\/cancers17071202","journal-title":"Cancers (Basel)"},{"key":"ref5","article-title":"Primary cutaneous diffuse large B-cell lymphoma, leg type, with multiple local relapses: case presentation and brief review of literature","volume":"17","author":"Patsatsi A","year":"2013","unstructured":"Patsatsi A, Kyriakou A, Karavasilis V, Panteliadou K, Sotiriadis D. Primary cutaneous diffuse large B-cell lymphoma, leg type, with multiple local relapses: case presentation and brief review of literature. Hippokratia. 2013, 17:174-6.","journal-title":"Hippokratia"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2021.279992","article-title":"A case series of primary cutaneous B-cell lymphomas with atypical presentations: diagnostic and therapeutic challenges","volume":"107","author":"Correia E","year":"2022","unstructured":"Correia E, Cha J, Krishnasamy S, O'Donnell M, Shi W, Porcu P, Nikbakht N. A case series of primary cutaneous B-cell lymphomas with atypical presentations: diagnostic and therapeutic challenges. Haematologica. 2022, 107:1014-6. 10.3324\/haematol.2021.279992","journal-title":"Haematologica"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00651","article-title":"Primary cutaneous B-cell lymphomas: an update","volume":"10","author":"Vitiello P","year":"2020","unstructured":"Vitiello P, Sica A, Ronchi A, Caccavale S, Franco R, Argenziano G. Primary cutaneous B-cell lymphomas: an update. Front Oncol. 2020, 10:651. 10.3389\/fonc.2020.00651","journal-title":"Front Oncol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_74_17","article-title":"A literature revision in primary cutaneous B-cell lymphoma","volume":"62","author":"Selva R","year":"2017","unstructured":"Selva R, Violetti SA, Delfino C, et al.. A literature revision in primary cutaneous B-cell lymphoma. Indian J Dermatol. 2017, 62:146-57. 10.4103\/ijd.IJD_74_17","journal-title":"Indian J Dermatol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.9.1144","article-title":"Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases","volume":"143","author":"Grange F","year":"2007","unstructured":"Grange F, Beylot-Barry M, Courville P, et al.. Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases. Arch Dermatol. 2007, 143:1144-50. 10.1001\/archderm.143.9.1144","journal-title":"Arch Dermatol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502","article-title":"WHO-EORTC classification for cutaneous lymphomas","volume":"105","author":"Willemze R","year":"2005","unstructured":"Willemze R, Jaffe ES, Burg G, et al.. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005, 105:3768-85. 10.1182\/blood-2004-09-3502","journal-title":"Blood"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022015851","article-title":"The International Consensus Classification of mature lymphoid neoplasms: a report from the clinical advisory council","volume":"140","author":"Campo E","year":"2022","unstructured":"Campo E, Jaffe ES, Cook JR, et al.. The International Consensus Classification of mature lymphoid neoplasms: a report from the clinical advisory council. Blood. 2022, 140:1229-53. 10.1182\/blood.2022015851","journal-title":"Blood"},{"key":"ref12","unstructured":"B-cell lymphomas. (2025). Accessed. July 23, 2026: https:\/\/www.nccn.org\/guidelines\/guidelines-detail?category=1&id=1480."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000522053","article-title":"Radiotherapy as a treatment option for local disease control in primary cutaneous diffuse large B-cell lymphoma, leg type","volume":"238","author":"Zehnder M","year":"2022","unstructured":"Zehnder M, Amarov B, Abrunhosa-Branquinho AN, et al.. Radiotherapy as a treatment option for local disease control in primary cutaneous diffuse large B-cell lymphoma, leg type. Dermatology. 2022, 238:967-76. 10.1159\/000522053","journal-title":"Dermatology"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2024.42.16_suppl.e19074","article-title":"Survival outcomes in primary cutaneous diffuse large B-cell lymphoma, leg type","volume":"42","author":"Baidoun F","year":"2024","unstructured":"Baidoun F, Hoppe B, Tun H, Moustafa M. Survival outcomes in primary cutaneous diffuse large B-cell lymphoma, leg type. J Clin Oncol. 2024, 42:19074. 10.1200\/JCO.2024.42.16_suppl.e19074","journal-title":"J Clin Oncol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2025.2506503","article-title":"A current view of the pathogenesis and treatment of primary cutaneous diffuse large B cell lymphoma - leg type","volume":"66","author":"Robak E","year":"2025","unstructured":"Robak E, Braun M, Robak T. A current view of the pathogenesis and treatment of primary cutaneous diffuse large B cell lymphoma - leg type. Leuk Lymphoma. 2025, 66:1603-14. 10.1080\/10428194.2025.2506503","journal-title":"Leuk Lymphoma"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007110.pub4","article-title":"Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early-stage Hodgkin's lymphoma","volume":"12","author":"Goldkuhle M","year":"2024","unstructured":"Goldkuhle M, Kreuzberger N, von Tresckow B, Eichenauer DA, Specht L, Monsef I, Skoetz N. Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early-stage Hodgkin's lymphoma. Cochrane Database Syst Rev. 2024, 12:CD007110. 10.1002\/14651858.CD007110.pub4","journal-title":"Cochrane Database Syst Rev"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_83_17","article-title":"Primary cutaneous B-cell lymphomas: case report of two cases","volume":"62","author":"Mishra S","year":"2017","unstructured":"Mishra S, Shelly D, Vinu Balraam KV, Bharadwaj R. Primary cutaneous B-cell lymphomas: case report of two cases. Indian J Dermatol. 2017, 62:675. 10.4103\/ijd.IJD_83_17","journal-title":"Indian J Dermatol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/ced\/llac044","article-title":"Bone involvement in primary cutaneous diffuse large B-cell lymphoma, leg-type","volume":"48","author":"Laurent C","year":"2023","unstructured":"Laurent C, Ram-Wolff C, Ingen-Housz-Oro S, et al.. Bone involvement in primary cutaneous diffuse large B-cell lymphoma, leg-type. Clin Exp Dermatol. 2023, 48:116-20. 10.1093\/ced\/llac044","journal-title":"Clin Exp Dermatol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/459666-radiation-monotherapy-for-primary-cutaneous-diffuse-large-b-cell-lymphoma-leg-type-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T13:20:38Z","timestamp":1786022438000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/459666-radiation-monotherapy-for-primary-cutaneous-diffuse-large-b-cell-lymphoma-leg-type-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,6]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.114059","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,6]]}}}