{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:28:49Z","timestamp":1786120129976,"version":"build-2736575974"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,6]]},"DOI":"10.7759\/cureus.114074","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T19:51:17Z","timestamp":1786045877000},"source":"Crossref","is-referenced-by-count":0,"title":["Optic Nerve Head Cotton Wool Spots Mimicking Inflammatory Optic Neuropathy in Central Retinal Vein Occlusion"],"prefix":"10.7759","author":[{"given":"Carolina A","family":"Jimenez Soto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ninel L","family":"Gregori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byron L","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam","family":"Vila-Delgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luma","family":"Al-Attar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31559-2","article-title":"Retinal vascular occlusions","volume":"396","author":"Scott IU","year":"2020","unstructured":"Scott IU, Campochiaro PA, Newman NJ, Biousse V. Retinal vascular occlusions. Lancet. 2020, 396:1927-40. 10.1016\/S0140-6736(20)31559-2","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.04.019","article-title":"Natural history of visual outcome in central retinal vein occlusion","volume":"118","author":"Hayreh SS","year":"2011","unstructured":"Hayreh SS, Podhajsky PA, Zimmerman MB. Natural history of visual outcome in central retinal vein occlusion. Ophthalmology. 2011, 118:119-133.e1-2. 10.1016\/j.ophtha.2010.04.019","journal-title":"Ophthalmology"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.07.080","article-title":"A longitudinal analysis of risk factors associated with central retinal vein occlusion","volume":"120","author":"Stem MS","year":"2013","unstructured":"Stem MS, Talwar N, Comer GM, Stein JD. A longitudinal analysis of risk factors associated with central retinal vein occlusion. Ophthalmology. 2013, 120:362-70. 10.1016\/j.ophtha.2012.07.080","journal-title":"Ophthalmology"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.61.3.177","article-title":"The role of axoplasmic transport in the pathogenesis of retinal cotton-wool spots","volume":"61","author":"McLeod D","year":"1977","unstructured":"McLeod D, Marshall J, Kohner EM, Bird AC. The role of axoplasmic transport in the pathogenesis of retinal cotton-wool spots. Br J Ophthalmol. 1977, 61:177-91. 10.1136\/bjo.61.3.177","journal-title":"Br J Ophthalmol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000256","article-title":"Fundus changes in central retinal vein occlusion","volume":"35","author":"Hayreh SS","year":"2015","unstructured":"Hayreh SS, Zimmerman MB. Fundus changes in central retinal vein occlusion. Retina. 2015, 35:29-42. 10.1097\/IAE.0000000000000256","journal-title":"Retina"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.058347","article-title":"Why cotton wool spots should not be regarded as retinal nerve fibre layer infarcts","volume":"89","author":"McLeod D","year":"2005","unstructured":"McLeod D. Why cotton wool spots should not be regarded as retinal nerve fibre layer infarcts. Br J Ophthalmol. 2005, 89:229-37. 10.1136\/bjo.2004.058347","journal-title":"Br J Ophthalmol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.06.054","article-title":"Hyperreflective sign in resolved cotton wool spots using high-resolution optical coherence tomography and optical coherence tomography ophthalmoscopy","volume":"114","author":"Kozak I","year":"2007","unstructured":"Kozak I, Bartsch DU, Cheng L, Freeman WR. Hyperreflective sign in resolved cotton wool spots using high-resolution optical coherence tomography and optical coherence tomography ophthalmoscopy. Ophthalmology. 2007, 114:537-43. 10.1016\/j.ophtha.2006.06.054","journal-title":"Ophthalmology"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-304900","article-title":"Spectral domain optical coherence tomography findings in eyes with acute ischaemic retinal whitening","volume":"99","author":"Coady PA","year":"2015","unstructured":"Coady PA, Cunningham ET Jr, Vora RA, et al.. Spectral domain optical coherence tomography findings in eyes with acute ischaemic retinal whitening. Br J Ophthalmol. 2015, 99:586-92. 10.1136\/bjophthalmol-2014-304900","journal-title":"Br J Ophthalmol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(16)30237-X","article-title":"Diagnosis and clinical features of common optic neuropathies","volume":"15","author":"Biousse V","year":"2016","unstructured":"Biousse V, Newman NJ. Diagnosis and clinical features of common optic neuropathies. Lancet Neurol. 2016, 15:1355-67. 10.1016\/S1474-4422(16)30237-X","journal-title":"Lancet Neurol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17554-5","article-title":"The eye in systemic inflammatory diseases","volume":"364","author":"McCluskey P","year":"2004","unstructured":"McCluskey P, Powell RJ. The eye in systemic inflammatory diseases. Lancet. 2004, 364:2125-33. 10.1016\/S0140-6736(04)17554-5","journal-title":"Lancet"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.62.14.1","article-title":"Collateral vessel development in central and branch retinal vein occlusions are associated with worse visual and anatomic outcomes","volume":"62","author":"Arrigo A","year":"2021","unstructured":"Arrigo A, Aragona E, Lattanzio R, Scalia G, Bandello F, Parodi MB. Collateral vessel development in central and branch retinal vein occlusions are associated with worse visual and anatomic outcomes. Invest Ophthalmol Vis Sci. 2021, 62:1. 10.1167\/iovs.62.14.1","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(22)00173-9","article-title":"Imaging of the optic nerve: technological advances and future prospects","volume":"21","author":"Biousse V","year":"2022","unstructured":"Biousse V, Danesh-Meyer HV, Saindane AM, Lamirel C, Newman NJ. Imaging of the optic nerve: technological advances and future prospects. Lancet Neurol. 2022, 21:1135-50. 10.1016\/S1474-4422(22)00173-9","journal-title":"Lancet Neurol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/508400-optic-nerve-head-cotton-wool-spots-mimicking-inflammatory-optic-neuropathy-in-central-retinal-vein-occlusion","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T19:51:17Z","timestamp":1786045877000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/508400-optic-nerve-head-cotton-wool-spots-mimicking-inflammatory-optic-neuropathy-in-central-retinal-vein-occlusion"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,6]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.114074","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,6]]}}}