{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T03:42:32Z","timestamp":1786246952586,"version":"build-2736575974"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,8]]},"DOI":"10.7759\/cureus.114184","type":"journal-article","created":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T03:09:03Z","timestamp":1786244943000},"source":"Crossref","is-referenced-by-count":0,"title":["The Unfolding Mystery of Hemophagocytic Lymphohistiocytosis in Pregnancy: A Case Report"],"prefix":"10.7759","author":[{"given":"Sebastian","family":"Asteguieta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Torselli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Diaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13432","article-title":"Incidence and survival of haemophagocytic lymphohistiocytosis: a population-based cohort study from England","volume":"291","author":"West J","year":"2022","unstructured":"West J, Card TR, Bishton MJ, et al.. Incidence and survival of haemophagocytic lymphohistiocytosis: a population-based cohort study from England. J Intern Med. 2022, 291:493-504. 10.1111\/joim.13432","journal-title":"J Intern Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-021-01790-9","article-title":"Hemophagocytic lymphohistiocytosis during pregnancy: a review of the literature in epidemiology, pathogenesis, diagnosis and treatment","volume":"16","author":"Liu L","year":"2021","unstructured":"Liu L, Cui Y, Zhou Q, Zhao H, Li X. Hemophagocytic lymphohistiocytosis during pregnancy: a review of the literature in epidemiology, pathogenesis, diagnosis and treatment. Orphanet J Rare Dis. 2021, 16:281. 10.1186\/s13023-021-01790-9","journal-title":"Orphanet J Rare Dis"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/jog.15133","article-title":"Management of hemophagocytic lymphohistiocytosis in pregnancy: case series study and literature review","volume":"48","author":"Liu C","year":"2022","unstructured":"Liu C, Gao J, Liu J. Management of hemophagocytic lymphohistiocytosis in pregnancy: case series study and literature review. J Obstet Gynaecol Res. 2022, 48:610-20. 10.1111\/jog.15133","journal-title":"J Obstet Gynaecol Res"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.70013","article-title":"Hemophagocytic lymphohistiocytosis in pregnancy: a systematic review of case reports and case series","volume":"100","author":"Abdelhay A","year":"2025","unstructured":"Abdelhay A, Eltaher B, Reghis M, et al.. Hemophagocytic lymphohistiocytosis in pregnancy: a systematic review of case reports and case series. Am J Hematol. 2025, 100:1828-38. 10.1002\/ajh.70013","journal-title":"Am J Hematol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/art.42636","article-title":"The 2022 EULAR\/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis\/macrophage activation syndrome (HLH\/MAS)","volume":"75","author":"Shakoory B","year":"2023","unstructured":"Shakoory B, Geerlinks A, Wilejto M, et al.. The 2022 EULAR\/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis\/macrophage activation syndrome (HLH\/MAS). Arthritis Rheumatol. 2023, 75:1714-32. 10.1002\/art.42636","journal-title":"Arthritis Rheumatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1189236","article-title":"Clinical characteristics and outcomes of pregnancy-associated hemophagocytic lymphohistiocytosis: A systematic review","volume":"14","author":"Wang Y","year":"2023","unstructured":"Wang Y, Wang Z, Zhang J, et al.. Clinical characteristics and outcomes of pregnancy-associated hemophagocytic lymphohistiocytosis: A systematic review. Front Immunol. 2023, 14:1189236. 10.3389\/fimmu.2023.1189236","journal-title":"Front Immunol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9695367","article-title":"Hemophagocytic lymphohistiocytosis in pregnancy: a case series and review of the current literature","volume":"2019","author":"Parrott J","year":"2019","unstructured":"Parrott J, Shilling A, Male HJ, Holland M, Clark-Ganheart CA. Hemophagocytic lymphohistiocytosis in pregnancy: a case series and review of the current literature. Case Rep Obstet Gynecol. 2019, 2019:9695367. 10.1155\/2019\/9695367","journal-title":"Case Rep Obstet Gynecol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2020.101515","article-title":"Hemophagocytic lymphohistiocytosis: An update on pathogenesis, diagnosis, and therapy","volume":"34","author":"Griffin G","year":"2020","unstructured":"Griffin G, Shenoi S, Hughes GC. Hemophagocytic lymphohistiocytosis: An update on pathogenesis, diagnosis, and therapy. Best Pract Res Clin Rheumatol. 2020, 34:101515. 10.1016\/j.berh.2020.101515","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13779","article-title":"Validation of the HScore and the HLH-2004 diagnostic criteria for the diagnosis of hemophagocytic lymphohistiocytosis in a multicenter cohort","volume":"109","author":"Bilston L","year":"2022","unstructured":"Bilston L, Croden J, Taparia M, Karkhaneh M, Grossman J, Sun HL. Validation of the HScore and the HLH-2004 diagnostic criteria for the diagnosis of hemophagocytic lymphohistiocytosis in a multicenter cohort. Eur J Haematol. 2022, 109:129-37. 10.1111\/ejh.13779","journal-title":"Eur J Haematol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1210041","article-title":"Approaching hemophagocytic lymphohistiocytosis","volume":"14","author":"Chinnici A","year":"2023","unstructured":"Chinnici A, Beneforti L, Pegoraro F, et al.. Approaching hemophagocytic lymphohistiocytosis. Front Immunol. 2023, 14:1210041. 10.3389\/fimmu.2023.1210041","journal-title":"Front Immunol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2016.05.001","article-title":"Hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) in adults: a systematic scoping review","volume":"30","author":"Hayden A","year":"2016","unstructured":"Hayden A, Park S, Giustini D, Lee AY, Chen LY. Hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) in adults: a systematic scoping review. Blood Rev. 2016, 30:411-20. 10.1016\/j.blre.2016.05.001","journal-title":"Blood Rev"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/516067-the-unfolding-mystery-of-hemophagocytic-lymphohistiocytosis-in-pregnancy-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T03:09:06Z","timestamp":1786244946000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/516067-the-unfolding-mystery-of-hemophagocytic-lymphohistiocytosis-in-pregnancy-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,8]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.114184","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,8]]}}}