{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T06:33:33Z","timestamp":1786516413435,"version":"build-2736575974"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,11]]},"DOI":"10.7759\/cureus.114387","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T06:16:12Z","timestamp":1786515372000},"source":"Crossref","is-referenced-by-count":0,"title":["Enterococcus faecalis Aortic Valve Endocarditis Masquerading As Urinary Tract Infection: Diagnostic Delay, Septic Embolic Strokes, and a Fatal Therapeutic Impasse"],"prefix":"10.7759","author":[{"given":"Muhammad  A","family":"Tariq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayesha","family":"Munir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Hamza","family":"Waheed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannay E","family":"Bellamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01098-5","article-title":"Infective endocarditis","volume":"404","author":"Li M","year":"2024","unstructured":"Li M, Kim JB, Sastry BKS, Chen M. Infective endocarditis. Lancet. 2024, 404:377-92. 10.1016\/S0140-6736(24)01098-5","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-025-22100-z","article-title":"Global, regional, and national burden of infective endocarditis from 2010 to 2021 and predictions for the next five years: results from the Global Burden of Disease Study 2021","volume":"25","author":"Lin L","year":"2025","unstructured":"Lin L, Xu J, Chai Y, Wu W. Global, regional, and national burden of infective endocarditis from 2010 to 2021 and predictions for the next five years: results from the Global Burden of Disease Study 2021. BMC Public Health. 2025, 25:1115. 10.1186\/s12889-025-22100-z","journal-title":"BMC Public Health"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2026.134449","article-title":"Variables associated with diagnostic delay and mortality in infective endocarditis: an observational retrospective study","volume":"454","author":"Brioschi G","year":"2026","unstructured":"Brioschi G, Mariani S, Occhino G, et al.. Variables associated with diagnostic delay and mortality in infective endocarditis: an observational retrospective study. Int J Cardiol. 2026, 454:134449. 10.1016\/j.ijcard.2026.134449","journal-title":"Int J Cardiol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.04.059","article-title":"Prevalence of infective endocarditis in Enterococcus faecalis bacteremia","volume":"74","author":"Dahl A","year":"2019","unstructured":"Dahl A, Iversen K, Tonder N, et al.. Prevalence of infective endocarditis in Enterococcus faecalis bacteremia. J Am Coll Cardiol. 2019, 74:193-201. 10.1016\/j.jacc.2019.04.059","journal-title":"J Am Coll Cardiol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac181","article-title":"Sign of the times: updating infective endocarditis diagnostic criteria to recognize Enterococcus faecalis as a typical endocarditis bacterium","volume":"75","author":"Dahl A","year":"2022","unstructured":"Dahl A, Fowler VG, Miro JM, Bruun NE. Sign of the times: updating infective endocarditis diagnostic criteria to recognize Enterococcus faecalis as a typical endocarditis bacterium. Clin Infect Dis. 2022, 75:1097-102. 10.1093\/cid\/ciac181","journal-title":"Clin Infect Dis"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.10.015","article-title":"Staphylococcus aureus infective endocarditis: JACC patient pathways","volume":"79","author":"Grapsa J","year":"2022","unstructured":"Grapsa J, Blauth C, Chandrashekhar YS, Prendergast B, Erb B Jr, Mack M, Fuster V. Staphylococcus aureus infective endocarditis: JACC patient pathways. J Am Coll Cardiol. 2022, 79:88-99. 10.1016\/j.jacc.2021.10.015","journal-title":"J Am Coll Cardiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000296","article-title":"Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association","volume":"132","author":"Baddour LM","year":"2015","unstructured":"Baddour LM, Wilson WR, Bayer AS, et al.. Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association. Circulation. 2015, 132:1435-86. 10.1161\/CIR.0000000000000296","journal-title":"Circulation"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4109358","article-title":"Cerebrovascular complications and infective endocarditis: impact of available evidence on clinical outcome","volume":"2018","author":"Schirone L","year":"2018","unstructured":"Schirone L, Iaccarino A, Saade W, et al.. Cerebrovascular complications and infective endocarditis: impact of available evidence on clinical outcome. Biomed Res Int. 2018, 2018:4109358. 10.1155\/2018\/4109358","journal-title":"Biomed Res Int"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5646348","article-title":"Neurocardiology: Cardiovascular changes and specific brain region Infarcts","volume":"2017","author":"Zou R","year":"2017","unstructured":"Zou R, Shi W, Tao J, Li H, Lin X, Yang S, Hua P. Neurocardiology: Cardiovascular changes and specific brain region Infarcts. Biomed Res Int. 2017, 2017:5646348. 10.1155\/2017\/5646348","journal-title":"Biomed Res Int"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11185275","article-title":"Optimal timing for cardiac surgery in infective endocarditis with neurological complications: a narrative review","volume":"18","author":"Siquier-Padilla J","year":"2022","unstructured":"Siquier-Padilla J, Cuervo G, Urra X, et al.. Optimal timing for cardiac surgery in infective endocarditis with neurological complications: a narrative review. J Clin Med. 2022, 18:5475. 10.3390\/jcm11185275","journal-title":"J Clin Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2023.12.043","article-title":"Recent insights into native valve infective endocarditis: JACC focus seminar 4\/4","volume":"83","author":"Dayer MJ","year":"2024","unstructured":"Dayer MJ, Quintero-Martinez JA, Thornhill MH, Chambers JB, Pettersson GB, Baddour LM. Recent insights into native valve infective endocarditis: JACC focus seminar 4\/4. J Am Coll Cardiol. 2024, 83:1431-43. 10.1016\/j.jacc.2023.12.043","journal-title":"J Am Coll Cardiol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.10.066","article-title":"Challenges in infective endocarditis","volume":"69","author":"Cahill TJ","year":"2017","unstructured":"Cahill TJ, Baddour LM, Habib G, et al.. Challenges in infective endocarditis. J Am Coll Cardiol. 2017, 69:325-44. 10.1016\/j.jacc.2016.10.066","journal-title":"J Am Coll Cardiol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12166","article-title":"Enterococcal endocarditis in the beginning of the 21st century: analysis from the international collaboration on endocarditis-prospective cohort study","volume":"19","author":"Chirouze C","year":"2013","unstructured":"Chirouze C, Athan E, Alla F, et al.. Enterococcal endocarditis in the beginning of the 21st century: analysis from the international collaboration on endocarditis-prospective cohort study. Clin Microbiol Infect. 2013, 19:1140-7. 10.1111\/1469-0691.12166","journal-title":"Clin Microbiol Infect"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz320","article-title":"Increased risk of ischemic stroke after treatment of infective endocarditis: a Danish, nationwide, propensity score-matched cohort study","volume":"70","author":"Klein CF","year":"2020","unstructured":"Klein CF, G\u00f8rtz S, Wohlfahrt J, N\u00f8rgaard Munch T, Melbye M, Bundgaard H, Iversen KK. Increased risk of ischemic stroke after treatment of infective endocarditis: a Danish, nationwide, propensity score-matched cohort study. Clin Infect Dis. 2020, 70:1186-92. 10.1093\/cid\/ciz320","journal-title":"Clin Infect Dis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.11.018","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines","volume":"77","author":"Otto CM","year":"2021","unstructured":"Otto CM, Nishimura RA, Bonow RO, et al.. 2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines. J Am Coll Cardiol. 2021, 77:e25-e197. 10.1016\/j.jacc.2020.11.018","journal-title":"J Am Coll Cardiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.01.077","article-title":"Multislice computed tomography in infective endocarditis: comparison with transesophageal echocardiography and intraoperative findings","volume":"53","author":"Feuchtner GM","year":"2009","unstructured":"Feuchtner GM, Stolzmann P, Dichtl W, et al.. Multislice computed tomography in infective endocarditis: comparison with transesophageal echocardiography and intraoperative findings. J Am Coll Cardiol. 2009, 53:436-44. 10.1016\/j.jacc.2008.01.077","journal-title":"J Am Coll Cardiol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/487829-enterococcus-faecalis-aortic-valve-endocarditis-masquerading-as-urinary-tract-infection-diagnostic-delay-septic-embolic-strokes-and-a-fatal-therapeutic-impasse","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T06:16:13Z","timestamp":1786515373000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/487829-enterococcus-faecalis-aortic-valve-endocarditis-masquerading-as-urinary-tract-infection-diagnostic-delay-septic-embolic-strokes-and-a-fatal-therapeutic-impasse"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,11]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.114387","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,11]]}}}