{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T01:24:07Z","timestamp":1787275447666,"version":"build-2736575974"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,20]]},"DOI":"10.7759\/cureus.114890","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:53:00Z","timestamp":1787273580000},"source":"Crossref","is-referenced-by-count":0,"title":["Improvement of Post-inflammatory Hyperpigmentation in a Second-Degree Burn Scar Following the NewMelan Depigmentation Protocol: A Case Report"],"prefix":"10.7759","author":[{"given":"Maribel  C","family":"Sanchez Meza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2022.04.017","article-title":"Treatment of hyperpigmentation after burn: a literature review","volume":"48","author":"Lupon E","year":"2022","unstructured":"Lupon E, Laloze J, Chaput B, et al.. Treatment of hyperpigmentation after burn: a literature review. Burns. 2022, 48:1055-68. 10.1016\/j.burns.2022.04.017","journal-title":"Burns"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/burnst\/tkad006","article-title":"Sustained induction of IP-10 by MRP8\/14 via the IFN\u03b2-IRF7 axis in macrophages exaggerates lung injury in endotoxemic mice","volume":"11","author":"Wang J","year":"2023","unstructured":"Wang J, Chen G, Li L, et al.. Sustained induction of IP-10 by MRP8\/14 via the IFN\u03b2-IRF7 axis in macrophages exaggerates lung injury in endotoxemic mice. Burns Trauma. 2023, 11:tkad006. 10.1093\/burnst\/tkad006","journal-title":"Burns Trauma"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.2020.4887","article-title":"Post-inflammatory hyperpigmentation: a review of treatment strategies","volume":"19","author":"Shenoy A","year":"2020","unstructured":"Shenoy A, Madan R. Post-inflammatory hyperpigmentation: a review of treatment strategies. J Drugs Dermatol. 2020, 19:763-8. 10.36849\/JDD.2020.4887","journal-title":"J Drugs Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-017-0333-6","article-title":"Postinflammatory hyperpigmentation: epidemiology, clinical presentation, pathogenesis and treatment","volume":"19","author":"Kaufman BP","year":"2018","unstructured":"Kaufman BP, Aman T, Alexis AF. Postinflammatory hyperpigmentation: epidemiology, clinical presentation, pathogenesis and treatment. Am J Clin Dermatol. 2018, 19:489-503. 10.1007\/s40257-017-0333-6","journal-title":"Am J Clin Dermatol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.19566","article-title":"Post-inflammatory hyperpigmentation: a systematic review of treatment outcomes","volume":"38","author":"Kashetsky N","year":"2024","unstructured":"Kashetsky N, Feschuk A, Pratt ME. Post-inflammatory hyperpigmentation: a systematic review of treatment outcomes. J Eur Acad Dermatol Venereol. 2024, 38:470-9. 10.1111\/jdv.19566","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/12034754241265716","article-title":"Treatment of post-inflammatory hyperpigmentation in skin of colour: a systematic review","volume":"28","author":"Mar K","year":"2024","unstructured":"Mar K, Khalid B, Maazi M, Ahmed R, Wang OJ, Khosravi-Hafshejani T. Treatment of post-inflammatory hyperpigmentation in skin of colour: a systematic review. J Cutan Med Surg. 2024, 28:473-80. 10.1177\/12034754241265716","journal-title":"J Cutan Med Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.13038","article-title":"A focused review on the pathophysiology of post-inflammatory hyperpigmentation","volume":"35","author":"Maghfour J","year":"2022","unstructured":"Maghfour J, Olayinka J, Hamzavi IH, Mohammad TF. A focused review on the pathophysiology of post-inflammatory hyperpigmentation. Pigment Cell Melanoma Res. 2022, 35:320-7. 10.1111\/pcmr.13038","journal-title":"Pigment Cell Melanoma Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0151-9638(18)30079-6","article-title":"L\u2019hyperpigmentation post-inflammatoire [Post-inflammatory hyperpigmentation]","volume":"143","author":"Passeron T","year":"2016","unstructured":"Passeron T. L\u2019hyperpigmentation post-inflammatoire [Post-inflammatory hyperpigmentation]. Ann Dermatol Venereol. 2016, 143:2. 10.1016\/S0151-9638(18)30079-6","journal-title":"Ann Dermatol Venereol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/1203475420957633","article-title":"Prophylaxis of post-inflammatory hyperpigmentation from energy-based device treatments: a review","volume":"25","author":"Wong IT","year":"2021","unstructured":"Wong IT, Richer V. Prophylaxis of post-inflammatory hyperpigmentation from energy-based device treatments: a review. J Cutan Med Surg. 2021, 25:77-86. 10.1177\/1203475420957633","journal-title":"J Cutan Med Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14916","article-title":"Management of post-inflammatory hyperpigmentation in skin of color: a short review","volume":"21","author":"Anvery N","year":"2022","unstructured":"Anvery N, Christensen RE, Dirr MA. Management of post-inflammatory hyperpigmentation in skin of color: a short review. J Cosmet Dermatol. 2022, 21:1837-40. 10.1111\/jocd.14916","journal-title":"J Cosmet Dermatol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.6485","article-title":"Getting to the core of contemporary therapies for post-inflammatory hyperpigmentation","volume":"21","author":"Naik P","year":"2022","unstructured":"Naik P. Getting to the core of contemporary therapies for post-inflammatory hyperpigmentation. J Drugs Dermatol. 2022, 21:276-83. 10.36849\/JDD.6485","journal-title":"J Drugs Dermatol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13823","article-title":"Treating hypertrophic scar, post-inflammatory hyperpigmentation, and post-inflammatory hypopigmentation with intense pulsed light","volume":"30","author":"Chan LK","year":"2024","unstructured":"Chan LK, Lee KW, Hung LC, et al.. Treating hypertrophic scar, post-inflammatory hyperpigmentation, and post-inflammatory hypopigmentation with intense pulsed light. Skin Res Technol. 2024, 30:e13823. 10.1111\/srt.13823","journal-title":"Skin Res Technol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/PSN.0000000000000563","article-title":"Evidence review: topical approaches to treating post-inflammatory hyperpigmentation","volume":"44","author":"Van Wicklin SA","year":"2024","unstructured":"Van Wicklin SA. Evidence review: topical approaches to treating post-inflammatory hyperpigmentation. Plast Aesthet Nurs (Phila). 2024, 44:93-5. 10.1097\/PSN.0000000000000563","journal-title":"Plast Aesthet Nurs (Phila)"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23173","article-title":"Treatment of post-inflammatory hyperpigmentation in patients with darker skin types using a low energy 1,927 nm non-ablative fractional laser: a retrospective photographic review analysis","volume":"52","author":"Bae YC","year":"2020","unstructured":"Bae YC, Rettig S, Weiss E, Bernstein L, Geronemus R. Treatment of post-inflammatory hyperpigmentation in patients with darker skin types using a low energy 1,927 nm non-ablative fractional laser: a retrospective photographic review analysis. Lasers Surg Med. 2020, 52:7-12. 10.1002\/lsm.23173","journal-title":"Lasers Surg Med"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2011.06.004","article-title":"Treatment of hyperpigmentation","volume":"30","author":"Woolery-Lloyd H","year":"2011","unstructured":"Woolery-Lloyd H, Kammer JN. Treatment of hyperpigmentation. Semin Cutan Med Surg. 2011, 30:171-5. 10.1016\/j.sder.2011.06.004","journal-title":"Semin Cutan Med Surg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.112167","article-title":"Diffuse facial melasma and lentigines treated with the NewMelan multimodal depigmentation protocol: a case report","volume":"18","author":"Krulig E","year":"2026","unstructured":"Krulig E. Diffuse facial melasma and lentigines treated with the NewMelan multimodal depigmentation protocol: a case report. Cureus. 2026, 18:e112167. 10.7759\/cureus.112167","journal-title":"Cureus"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.124.6.869","article-title":"The validity and practicality of sun-reactive skin types I through VI","volume":"124","author":"Fitzpatrick TB","year":"1988","unstructured":"Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol. 1988, 124:869-71. 10.1001\/archderm.124.6.869","journal-title":"Arch Dermatol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/502728-improvement-of-post-inflammatory-hyperpigmentation-in-a-second-degree-burn-scar-following-the-newmelan-depigmentation-protocol-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:53:01Z","timestamp":1787273581000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/502728-improvement-of-post-inflammatory-hyperpigmentation-in-a-second-degree-burn-scar-following-the-newmelan-depigmentation-protocol-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.114890","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,20]]}}}