{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:18:54Z","timestamp":1787800734600,"version":"build-2784847793"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,26]]},"DOI":"10.7759\/cureus.115261","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:42:51Z","timestamp":1787798571000},"source":"Crossref","is-referenced-by-count":0,"title":["Delayed Adverse Reactions Following Whole-Blood and Plateletpheresis Donation: A Prospective Observational Study From a Tertiary-Care Blood Center"],"prefix":"10.7759","author":[{"given":"Sunil","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tulika","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Solanki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelam","family":"Kumari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4103\/ajts.ajts_195_20","article-title":"National blood donor vigilance programme of India: analysis of donor adverse reactions reported during initial 2 years of implementation (2016 and 2017)","volume":"15","author":"Bisht A","year":"2021","unstructured":"Bisht A, Marwaha N, Arora S, Patidar GK, Chhabra R. National blood donor vigilance programme of India: analysis of donor adverse reactions reported during initial 2 years of implementation (2016 and 2017). Asian J Transfus Sci. 2021, 15:1-11. 10.4103\/ajts.ajts_195_20","journal-title":"Asian J Transfus Sci"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4103\/0973-6247.175384","article-title":"National blood donor vigilance programme: India","volume":"10","author":"Bisht A","year":"2016","unstructured":"Bisht A, Singh S, Marwaha N. National blood donor vigilance programme: India. Asian J Transfus Sci. 2016, 10:1-2. 10.4103\/0973-6247.175384","journal-title":"Asian J Transfus Sci"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12323","article-title":"Development of standard definitions for surveillance of complications related to blood donation","volume":"110","author":"Goldman M","year":"2016","unstructured":"Goldman M, Land K, Robillard P, Wiersum-Osselton J. Development of standard definitions for surveillance of complications related to blood donation. Vox Sang. 2016, 110:185-8. 10.1111\/vox.12323","journal-title":"Vox Sang"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2021.11.003","article-title":"Reporting of delayed adverse donor reactions in whole blood donors: just the tip of an iceberg!","volume":"29","author":"Kaur S","year":"2022","unstructured":"Kaur S, Mittal K, Kaur R, Kaur G, Kaur P, Sood T. Reporting of delayed adverse donor reactions in whole blood donors: just the tip of an iceberg!. Transfus Clin Biol. 2022, 29:141-6. 10.1016\/j.tracli.2021.11.003","journal-title":"Transfus Clin Biol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2013.06.003","article-title":"Frequency of adverse events in plateletpheresis donors in regional transfusion centre in North India","volume":"49","author":"Patidar GK","year":"2013","unstructured":"Patidar GK, Sharma RR, Marwaha N. Frequency of adverse events in plateletpheresis donors in regional transfusion centre in North India. Transfus Apher Sci. 2013, 49:244-8. 10.1016\/j.transci.2013.06.003","journal-title":"Transfus Apher Sci"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2450\/2013.0262-12","article-title":"Risk factors for complications in donors at first and repeat whole blood donation: a cohort study with assessment of the impact on donor return","volume":"12","author":"Wiersum-Osselton JC","year":"2014","unstructured":"Wiersum-Osselton JC, Kreek TM, Brand A, Veldhuizen I, van der Bom JG, de Kort W. Risk factors for complications in donors at first and repeat whole blood donation: a cohort study with assessment of the impact on donor return. Blood Transfus. 2014, 12:28-36. 10.2450\/2013.0262-12","journal-title":"Blood Transfus"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02397.x","article-title":"Blood donors and blood collection: delayed adverse reactions to blood donation","volume":"50","author":"Kamel H","year":"2010","unstructured":"Kamel H, Tomasulo P, Bravo M, Wiltbank T, Cusick R, James RC, Custer B. Blood donors and blood collection: delayed adverse reactions to blood donation. Transfusion. 2010, 50:556-65. 10.1111\/j.1537-2995.2009.02397.x","journal-title":"Transfusion"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2006.00905.x","article-title":"The effect of whole-blood donor adverse events on blood donor return rates","volume":"46","author":"Newman BH","year":"2006","unstructured":"Newman BH, Newman DT, Ahmad R, Roth AJ. The effect of whole-blood donor adverse events on blood donor return rates. Transfusion. 2006, 46:1374-9. 10.1111\/j.1537-2995.2006.00905.x","journal-title":"Transfusion"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.19.2279","article-title":"Adverse reactions to allogeneic whole blood donation by 16- and 17-year-olds","volume":"299","author":"Eder AF","year":"2008","unstructured":"Eder AF, Hillyer CD, Dy BA, Notari EP, Benjamin RJ. Adverse reactions to allogeneic whole blood donation by 16- and 17-year-olds. JAMA. 2008, 299:2279-86. 10.1001\/jama.299.19.2279","journal-title":"JAMA"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2450\/2015.0139-14","article-title":"Factors associated with psychological and physiological stress reactions to blood donation: a systematic review of the literature","volume":"13","author":"Hoogerwerf MD","year":"2015","unstructured":"Hoogerwerf MD, Veldhuizen IJ, De Kort WL, Frings-Dresen MH, Sluiter JK. Factors associated with psychological and physiological stress reactions to blood donation: a systematic review of the literature. Blood Transfus. 2015, 13:354-62. 10.2450\/2015.0139-14","journal-title":"Blood Transfus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4103\/0973-6247.98922","article-title":"Analysis of adverse events and predisposing factors in voluntary and replacement whole blood donors: a study from North India","volume":"6","author":"Agnihotri N","year":"2012","unstructured":"Agnihotri N, Marwaha N, Sharma RR. Analysis of adverse events and predisposing factors in voluntary and replacement whole blood donors: a study from North India. Asian J Transfus Sci. 2012, 6:155-60. 10.4103\/0973-6247.98922","journal-title":"Asian J Transfus Sci"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2016.10.009","article-title":"Post-donation telephonic interview of blood donors providing an insight into delayed adverse reactions: first attempt in India","volume":"56","author":"Tiwari AK","year":"2017","unstructured":"Tiwari AK, Aggarwal G, Dara RC, Arora D, Srivastava K, Raina V. Post-donation telephonic interview of blood donors providing an insight into delayed adverse reactions: first attempt in India. Transfus Apher Sci. 2017, 56:141-6. 10.1016\/j.transci.2016.10.009","journal-title":"Transfus Apher Sci"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2005.00595.x","article-title":"Estimating the probability of a blood donation adverse event based on 1000 interviewed whole-blood donors","volume":"45","author":"Newman BH","year":"2005","unstructured":"Newman BH, Roth AJ. Estimating the probability of a blood donation adverse event based on 1000 interviewed whole-blood donors. Transfusion. 2005, 45:1715-21. 10.1111\/j.1537-2995.2005.00595.x","journal-title":"Transfusion"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159\/000516049","article-title":"Blood donation-related adverse reactions: results of an online survey among donors in Germany (2018)","volume":"48","author":"Orru S","year":"2021","unstructured":"Orru S, Poetzsch K, Hoffelner M, Heiden M, Funk MB, Keller-Stanislawski B, Oberle D. Blood donation-related adverse reactions: results of an online survey among donors in Germany (2018). Transfus Med Hemother. 2021, 48:272-83. 10.1159\/000516049","journal-title":"Transfus Med Hemother"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_1273_19","article-title":"Delayed adverse reactions in whole blood donors: importance of active surveillance in identifying the missing gaps in the donor safety","volume":"157","author":"Gupta AM","year":"2023","unstructured":"Gupta AM, Bajpai M. Delayed adverse reactions in whole blood donors: importance of active surveillance in identifying the missing gaps in the donor safety. Indian J Med Res. 2023, 157:30-6. 10.4103\/ijmr.IJMR_1273_19","journal-title":"Indian J Med Res"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01745.x","article-title":"Faint and prefaint reactions in whole-blood donors: an analysis of predonation measurements and their predictive value","volume":"48","author":"Wiltbank TB","year":"2008","unstructured":"Wiltbank TB, Giordano GF, Kamel H, Tomasulo P, Custer B. Faint and prefaint reactions in whole-blood donors: an analysis of predonation measurements and their predictive value. Transfusion. 2008, 48:1799-808. 10.1111\/j.1537-2995.2008.01745.x","journal-title":"Transfusion"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02574.x","article-title":"Predonation hydration and applied muscle tension combine to reduce presyncopal reactions to blood donation","volume":"50","author":"France CR","year":"2010","unstructured":"France CR, Ditto B, Wissel ME, et al.. Predonation hydration and applied muscle tension combine to reduce presyncopal reactions to blood donation. Transfusion. 2010, 50:1257-64. 10.1111\/j.1537-2995.2009.02574.x","journal-title":"Transfusion"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3148.2000.00240.x","article-title":"Bruising following blood donation, its management and the response and subsequent return rates of affected donors","volume":"10","author":"Ranasinghe E","year":"2000","unstructured":"Ranasinghe E, Harrison JF. Bruising following blood donation, its management and the response and subsequent return rates of affected donors. Transfus Med. 2000, 10:113-6. 10.1046\/j.1365-3148.2000.00240.x","journal-title":"Transfus Med"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21902","article-title":"The impact of delayed and immediate adverse events on the intention of future donations in whole blood and plateletpheresis donors","volume":"36","author":"Gupta AM","year":"2021","unstructured":"Gupta AM, Bajpai M. The impact of delayed and immediate adverse events on the intention of future donations in whole blood and plateletpheresis donors. J Clin Apher. 2021, 36:621-7. 10.1002\/jca.21902","journal-title":"J Clin Apher"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2007.01000.x","article-title":"Complications related to blood donation: a population-based study","volume":"94","author":"Sorensen BS","year":"2008","unstructured":"Sorensen BS, Johnsen SP, Jorgensen J. Complications related to blood donation: a population-based study. Vox Sang. 2008, 94:132-7. 10.1111\/j.1423-0410.2007.01000.x","journal-title":"Vox Sang"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2007.01224.x","article-title":"The safety profile of automated collections: an analysis of more than 1 million collections","volume":"47","author":"Wiltbank TB","year":"2007","unstructured":"Wiltbank TB, Giordano GF. The safety profile of automated collections: an analysis of more than 1 million collections. Transfusion. 2007, 47:1002-5. 10.1111\/j.1537-2995.2007.01224.x","journal-title":"Transfusion"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s12288-016-0681-z","article-title":"Adverse events during apheresis procedures: audit at a tertiary hospital","volume":"33","author":"Dogra K","year":"2017","unstructured":"Dogra K, Fulzele P, Rout D, Chaurasia R, Coshic P, Chatterjee K. Adverse events during apheresis procedures: audit at a tertiary hospital. Indian J Hematol Blood Transfus. 2017, 33:106-8. 10.1007\/s12288-016-0681-z","journal-title":"Indian J Hematol Blood Transfus"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41091165.x","article-title":"Comprehensive analysis of citrate effects during plateletpheresis in normal donors","volume":"41","author":"Bolan CD","year":"2001","unstructured":"Bolan CD, Greer SE, Cecco SA, Oblitas JM, Rehak NN, Leitman SF. Comprehensive analysis of citrate effects during plateletpheresis in normal donors. Transfusion. 2001, 41:1165-71. 10.1046\/j.1537-2995.2001.41091165.x","journal-title":"Transfusion"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2005.00576.x","article-title":"Calcium and magnesium levels during automated plateletpheresis in normal donors","volume":"15","author":"Das SS","year":"2005","unstructured":"Das SS, Chaudhary R, Khetan D, Shukla JS, Agarwal P, Mishra RB. Calcium and magnesium levels during automated plateletpheresis in normal donors. Transfus Med. 2005, 15:233-6. 10.1111\/j.1365-3148.2005.00576.x","journal-title":"Transfus Med"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.2450\/2007.0005-07","article-title":"Adverse reactions during voluntary donation of blood and\/or blood components. A statistical-epidemiological study","volume":"5","author":"Crocco A","year":"2007","unstructured":"Crocco A, D'Elia D. Adverse reactions during voluntary donation of blood and\/or blood components. A statistical-epidemiological study. Blood Transfus. 2007, 5:143-52. 10.2450\/2007.0005-07","journal-title":"Blood Transfus"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.2450\/2010.0002-10","article-title":"Adverse reactions in whole blood donors: an Indian scenario","volume":"9","author":"Pathak C","year":"2011","unstructured":"Pathak C, Pujani M, Pahuja S, Jain M. Adverse reactions in whole blood donors: an Indian scenario. Blood Transfus. 2011, 9:46-9. 10.2450\/2010.0002-10","journal-title":"Blood Transfus"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21753","article-title":"Delayed adverse events in male plateletpheresis donors: initial insights on donor safety","volume":"35","author":"Gupta AM","year":"2020","unstructured":"Gupta AM, Bajpai M. Delayed adverse events in male plateletpheresis donors: initial insights on donor safety. J Clin Apher. 2020, 35:18-24. 10.1002\/jca.21753","journal-title":"J Clin Apher"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01674.x","article-title":"Risk factors for acute, moderate to severe donor reactions associated with multicomponent apheresis collections","volume":"48","author":"Yuan S","year":"2008","unstructured":"Yuan S, Gornbein J, Smeltzer B, Ziman AF, Lu Q, Goldfinger D. Risk factors for acute, moderate to severe donor reactions associated with multicomponent apheresis collections. Transfusion. 2008, 48:1213-9. 10.1111\/j.1537-2995.2008.01674.x","journal-title":"Transfusion"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13694","article-title":"A national surveillance system for continuous monitoring of blood transfusion safety: German haemovigilance data","volume":"119","author":"Berg P","year":"2024","unstructured":"Berg P, Heiden M, M\u00fcller S, et al.. A national surveillance system for continuous monitoring of blood transfusion safety: German haemovigilance data. Vox Sang. 2024, 119:953-62. 10.1111\/vox.13694","journal-title":"Vox Sang"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/509786-delayed-adverse-reactions-following-whole-blood-and-plateletpheresis-donation-a-prospective-observational-study-from-a-tertiary-care-blood-center","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:42:53Z","timestamp":1787798573000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/509786-delayed-adverse-reactions-following-whole-blood-and-plateletpheresis-donation-a-prospective-observational-study-from-a-tertiary-care-blood-center"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":29,"URL":"https:\/\/doi.org\/10.7759\/cureus.115261","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,26]]}}}