{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T12:16:12Z","timestamp":1788178572361,"version":"build-2803163510"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,31]]},"DOI":"10.7759\/cureus.115493","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:33:10Z","timestamp":1788175990000},"source":"Crossref","is-referenced-by-count":0,"title":["Undocumented Anxiolytic and Sedative Use and Its Association With Depressive and Anxiety Symptoms in Primary Care Patients Without Registered Mental Disorders"],"prefix":"10.7759","author":[{"given":"Sabina","family":"Ademovic Dzambic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danijel","family":"Gajic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emina","family":"Bajric Custo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Branislav","family":"Milic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senada","family":"Selmanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dzana","family":"Nuhanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lejla","family":"Hodzic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inela","family":"Kadric","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Cemalovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanda","family":"Kreitmayer Pestic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"World mental health report. transforming mental health for all. Geneva: World Health Organization. (2026). Accessed: July 6, 2026: https:\/\/www.who.int\/publications\/i\/item\/9789240049338."},{"key":"ref2","unstructured":"Mental disorders. Geneva. World Health Organization. (2026). Accessed: July 6, 2026: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/mental-disorders."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1037\/fsh0000229","article-title":"You can't treat what you don't diagnose: an analysis of the recognition of somatic presentations of depression and anxiety in primary care","volume":"34","author":"Gates K","year":"2016","unstructured":"Gates K, Petterson S, Wingrove P, Miller B, Klink K. You can't treat what you don't diagnose: an analysis of the recognition of somatic presentations of depression and anxiety in primary care. Fam Syst Health. 2016, 34:317-329. 10.1037\/fsh0000229","journal-title":"Fam Syst Health"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102507","article-title":"Prescribing and deprescribing guidance for benzodiazepine and benzodiazepine receptor agonist use in adults with depression, anxiety, and insomnia: an international scoping review","volume":"70","author":"Brandt J","year":"2024","unstructured":"Brandt J, Bressi J, L\u00ea ML, et al.. Prescribing and deprescribing guidance for benzodiazepine and benzodiazepine receptor agonist use in adults with depression, anxiety, and insomnia: an international scoping review. EClinMed. 2024, 70:102507. 10.1016\/j.eclinm.2024.102507","journal-title":"EClinMed"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-025-09499-2","article-title":"Joint Clinical Practice guideline on benzodiazepine tapering: Considerations when risks outweigh benefits","volume":"40","author":"Brunner E","year":"2025","unstructured":"Brunner E, Chen CA, Klein T, et al.. Joint Clinical Practice guideline on benzodiazepine tapering: Considerations when risks outweigh benefits. J Gen Intern Med. 2025, 40:2814-2859. 10.1007\/s11606-025-09499-2","journal-title":"J Gen Intern Med"},{"key":"ref6","unstructured":"gencija za lijekove i medicinska sredstva Bosne i Hercegovine. Izvje\u0161taj o prometu i potro\u0161nji lijekova u Bosni i Hercegovini za 2024. godinu. (2026). Accessed. July 6, 2026: https:\/\/almbih.gov.ba\/wp-content\/uploads\/2025\/07\/IZVJESTAJpromet2024-14072025.pdf."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14537","article-title":"Non-medical use of benzodiazepines and GABA analogues in Europe","volume":"87","author":"Hockenhull J","year":"2021","unstructured":"Hockenhull J, Amioka E, Black JC, et al.. Non-medical use of benzodiazepines and GABA analogues in Europe. Br J Clin Pharmacol. 2021, 87:1684-1694. 10.1111\/bcp.14537","journal-title":"Br J Clin Pharmacol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14397","article-title":"Nonmedical use of benzodiazepines and Z-drugs in the UK","volume":"87","author":"Hockenhull J","year":"2021","unstructured":"Hockenhull J, Black JC, Haynes CM, Rockhill K, Dargan PI, Dart RC, Wood DM. Nonmedical use of benzodiazepines and Z-drugs in the UK. Br J Clin Pharmacol. 2021, 87:1676-1683. 10.1111\/bcp.14397","journal-title":"Br J Clin Pharmacol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-024-01153-1","article-title":"Self-medication among general population in the European Union: prevalence and associated factors","volume":"39","author":"Yeamans S","year":"2024","unstructured":"Yeamans S, Gil-de-Miguel \u00c1, Hern\u00e1ndez-Barrera V, Carrasco-Garrido P. Self-medication among general population in the European Union: prevalence and associated factors. Eur J Epidemiol. 2024, 39:977-990. 10.1007\/s10654-024-01153-1","journal-title":"Eur J Epidemiol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3325\/cmj.2012.53.53","article-title":"Pharmacy network and access to medicines in selected eastern European countries: comparative analysis","volume":"53","author":"Laki\u0107 D","year":"2012","unstructured":"Laki\u0107 D, Tasi\u0107 L, Kos M, Petrova G, Stoimenova A, Krajnovi\u0107 D. Pharmacy network and access to medicines in selected eastern European countries: comparative analysis. Croat Med J. 2012, 53:53-59. 10.3325\/cmj.2012.53.53","journal-title":"Croat Med J"},{"key":"ref11","unstructured":"Ministry of Security of Bosnia and Herzegovina. General population survey on substance use in Bosnia and Herzegovina 2018. (2026). Accessed. July 7, 2026: https:\/\/www.euda.europa.eu."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"16","author":"Kroenke K","year":"2001","unstructured":"Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001, 16:606-613. 10.1046\/j.1525-1497.2001.016009606.x","journal-title":"J Gen Intern Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"Spitzer RL","year":"2006","unstructured":"Spitzer RL, Kroenke K, Williams JB, L\u00f6we B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006, 166:1092-1097. 10.1001\/archinte.166.10.1092","journal-title":"Arch Intern Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.09.131","article-title":"Screening for depression in primary care with Patient Health Questionnaire-9 (PHQ-9): a systematic review","volume":"279","author":"Costantini L","year":"2021","unstructured":"Costantini L, Pasquarella C, Odone A, et al.. Screening for depression in primary care with Patient Health Questionnaire-9 (PHQ-9): a systematic review. J Affect Disord. 2021, 279:473-483. 10.1016\/j.jad.2020.09.131","journal-title":"J Affect Disord"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n2183","article-title":"Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression: updated systematic review and individual participant data meta-analysis","volume":"375","author":"Negeri ZF","year":"2021","unstructured":"Negeri ZF, Levis B, Sun Y, et al.. Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression: updated systematic review and individual participant data meta-analysis. BMJ. 2021, 375:n2183. 10.1136\/bmj.n2183","journal-title":"BMJ"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.6369","article-title":"Anxiety screening: evidence report and systematic review for the US Preventive Services Task Force","volume":"329","author":"O'Connor EA","year":"2023","unstructured":"O'Connor EA, Henninger ML, Perdue LA, Coppola EL, Thomas RG, Gaynes BN. Anxiety screening: evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2023, 329:2171-2184. 10.1001\/jama.2023.6369","journal-title":"JAMA"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1177\/00368504221135469","article-title":"Factors associated with gender and sex differences in anxiety prevalence and comorbidity: a systematic review","volume":"105","author":"Farhane-Medina NZ","year":"2022","unstructured":"Farhane-Medina NZ, Luque B, Tabernero C, Castillo-May\u00e9n R. Factors associated with gender and sex differences in anxiety prevalence and comorbidity: a systematic review. Sci Prog. 2022, 105:368504221135469. 10.1177\/00368504221135469","journal-title":"Sci Prog"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.06.090","article-title":"Socioeconomic status and depressive symptoms: an individual-participant data meta-analysis on range restriction and measurement in the United States","volume":"314","author":"Korous KM","year":"2022","unstructured":"Korous KM, Bradley RH, Luthar SS, Li L, Levy R, Cahill KM, Rogers CR. Socioeconomic status and depressive symptoms: an individual-participant data meta-analysis on range restriction and measurement in the United States. J Affect Disord. 2022, 314:50-58. 10.1016\/j.jad.2022.06.090","journal-title":"J Affect Disord"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159\/000533263","article-title":"Depression and anxiety trajectories in chronic disease: a systematic review and meta-analysis","volume":"92","author":"Scott AJ","year":"2023","unstructured":"Scott AJ, Correa AB, Bisby MA, Dear BF. Depression and anxiety trajectories in chronic disease: a systematic review and meta-analysis. Psychother Psychosom. 2023, 92:227-242. 10.1159\/000533263","journal-title":"Psychother Psychosom"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/528737-undocumented-anxiolytic-and-sedative-use-and-its-association-with-depressive-and-anxiety-symptoms-in-primary-care-patients-without-registered-mental-disorders","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:33:12Z","timestamp":1788175992000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/528737-undocumented-anxiolytic-and-sedative-use-and-its-association-with-depressive-and-anxiety-symptoms-in-primary-care-patients-without-registered-mental-disorders"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.115493","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,31]]}}}